dantrolene has been researched along with Chagas Disease in 1 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Chagas Disease: Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The treatment with dantrolene restored the dystrophin and calpain levels near control levels." | 1.46 | Dantrolene improves in vitro structural changes induced by serum from Trypanosoma cruzi-infected mice. ( Celes, MR; Jelicks, LA; Malvestio, LM; Prado, CM; Tanowitz, HB, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Malvestio, LM | 1 |
| Celes, MR | 1 |
| Jelicks, LA | 1 |
| Tanowitz, HB | 1 |
| Prado, CM | 1 |
1 other study available for dantrolene and Chagas Disease
| Article | Year |
|---|---|
Dantrolene improves in vitro structural changes induced by serum from Trypanosoma cruzi-infected mice.
Topics: Animals; Animals, Newborn; Cells, Cultured; Chagas Disease; Dantrolene; Dystrophin; Fluorescent Anti | 2017 |