dantrolene has been researched along with Central Nervous System Diseases in 3 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Central Nervous System Diseases: Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mean dantrolene dose was 582 mg/d in fatal cases and 263 mg/d in the nonfatal group." | 1.28 | Dantrolene sodium and hepatic injury. ( Chan, CH, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Daoudai, P | 1 |
| Delacour, JL | 1 |
| Chan, CH | 1 |
| Young, RR | 1 |
3 other studies available for dantrolene and Central Nervous System Diseases
| Article | Year |
|---|---|
Treatment of neuroleptic malignant syndrome with dantrolene.
Topics: Central Nervous System Diseases; Dantrolene; Diagnosis, Differential; Humans; Malignant Hyperthermia | 1982 |
Dantrolene sodium and hepatic injury.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biopsy; Central Nervous System Diseases; Chemical and Dr | 1990 |
The physiology of spasticity and its response to therapy.
Topics: Animals; Baclofen; Central Nervous System Diseases; Dantrolene; Diazepam; Humans; Motor Neurons; Mus | 1988 |