dantrolene has been researched along with Catatonic Rigidity in 27 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Experimental rabbits treated with haloperidol (1 mg/kg) by intramuscular injection, were studied for the diagnostic symptoms of increased muscle rigidity, elevated body temperature, and high serum creatine phosphokinase (CPK) level." | 7.69 | Development of an animal model for neuroleptic malignant syndrome: heat-exposed rabbits with haloperidol and atropine administration exhibit increased muscle activity, hyperthermia, and high serum creatine phosphokinase level. ( Hosono, T; Ikura, Y; Kudo, T; Niigawa, H; Nishimura, T; Sakamoto, S; Takeda, M; Taniguchi, N; Tanii, H, 1996) |
| "Clozapine is an atypical neuroleptic drug that was initially thought not to cause neuroleptic malignant syndrome (NMS)." | 7.68 | Neuroleptic malignant syndrome and clozapine. ( Minnema, AM; Reddig, S; Tandon, R, 1993) |
| "The use of dantrolene to reverse severe unexplained postanaesthetic muscle rigidity in a previously "healthy" 13-year-old male is described." | 7.67 | Reversal of prolonged postoperative muscle rigidity by dantrolene: a case report. ( Dhandha, SK, 1988) |
| " Experimental rabbits treated with haloperidol (1 mg/kg) by intramuscular injection, were studied for the diagnostic symptoms of increased muscle rigidity, elevated body temperature, and high serum creatine phosphokinase (CPK) level." | 3.69 | Development of an animal model for neuroleptic malignant syndrome: heat-exposed rabbits with haloperidol and atropine administration exhibit increased muscle activity, hyperthermia, and high serum creatine phosphokinase level. ( Hosono, T; Ikura, Y; Kudo, T; Niigawa, H; Nishimura, T; Sakamoto, S; Takeda, M; Taniguchi, N; Tanii, H, 1996) |
| "Clozapine is an atypical neuroleptic drug that was initially thought not to cause neuroleptic malignant syndrome (NMS)." | 3.68 | Neuroleptic malignant syndrome and clozapine. ( Minnema, AM; Reddig, S; Tandon, R, 1993) |
| "The use of dantrolene to reverse severe unexplained postanaesthetic muscle rigidity in a previously "healthy" 13-year-old male is described." | 3.67 | Reversal of prolonged postoperative muscle rigidity by dantrolene: a case report. ( Dhandha, SK, 1988) |
| " Muscle rigidity was not affected by etybenzatropine or diazepam, but dantrolene, a direct-acting skeletal muscle relaxant, provided muscle relaxation with a concomitant decrease of fever and serum creatine kinase." | 3.66 | Beneficial effects of dantrolene in the treatment of neuroleptic malignant syndrome: a report of two cases. ( Bismuth, C; Conso, F; de Rohan-Chabot, P; Elkharrat, D; Gajdos, P; Goulon, M, 1983) |
| "A 38-year-old man diagnosed as esophageal achalasia developed masseter muscle rigidity after intravenous suxamethonium during anesthetic induction." | 1.32 | [Masseter muscle rigidity after suxamethonium during induction and postoperative abortive malignant hyperthermia in a patient with esophageal achalasia]. ( Anzai, T; Arakawa, Y; Hoka, S; Kanai, A; Kuroiwa, M; Okamoto, H, 2004) |
| "The true incidence of malignant hyperthermia is unknown, but the frequency has been estimated as high as 1/14,000 anesthetic events." | 1.26 | Malignant hyperthermia. ( Nissen, RL; Yonkers, AJ, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (70.37) | 18.7374 |
| 1990's | 5 (18.52) | 18.2507 |
| 2000's | 2 (7.41) | 29.6817 |
| 2010's | 1 (3.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Migita, T | 1 |
| Mukaida, K | 1 |
| Kobayashi, M | 1 |
| Hamada, H | 1 |
| Kawamoto, M | 1 |
| Arakawa, Y | 1 |
| Kuroiwa, M | 1 |
| Anzai, T | 1 |
| Kanai, A | 1 |
| Okamoto, H | 1 |
| Hoka, S | 1 |
| Brvar, M | 1 |
| Bunc, M | 1 |
| Goekoop, JG | 1 |
| Carbaat, PA | 1 |
| Daoudai, P | 1 |
| Delacour, JL | 1 |
| Neppe, VM | 1 |
| Lazarus, A | 1 |
| Nissen, RL | 1 |
| Yonkers, AJ | 1 |
| Byrd, JP | 1 |
| Goulon, M | 2 |
| de Rohan-Chabot, P | 1 |
| Elkharrat, D | 2 |
| Gajdos, P | 1 |
| Bismuth, C | 2 |
| Conso, F | 2 |
| Kawajiri, S | 1 |
| Kojima, H | 1 |
| Akashi, A | 1 |
| May, DC | 1 |
| Morris, SW | 1 |
| Stewart, RM | 1 |
| Fenton, BJ | 1 |
| Gaffney, FA | 1 |
| de Rohan Chabot, P | 1 |
| Reddig, S | 1 |
| Minnema, AM | 1 |
| Tandon, R | 1 |
| Tanii, H | 1 |
| Taniguchi, N | 1 |
| Niigawa, H | 1 |
| Hosono, T | 1 |
| Ikura, Y | 1 |
| Sakamoto, S | 1 |
| Kudo, T | 1 |
| Nishimura, T | 1 |
| Takeda, M | 1 |
| Shi, Y | 1 |
| Storella, RJ | 1 |
| Keykhah, MM | 1 |
| Rosenberg, H | 1 |
| Hall, GM | 1 |
| Lucke, JN | 1 |
| Lister, D | 1 |
| Imoto, Y | 1 |
| Fukuda, Y | 1 |
| Yokoyama, H | 1 |
| Miyake, T | 1 |
| Larner, AJ | 1 |
| Greenberg, MS | 1 |
| Gorelick, PB | 1 |
| ten Holter, JB | 1 |
| Schellens, RL | 1 |
| Dhandha, SK | 1 |
| Abbott, RJ | 1 |
| Loizou, LA | 1 |
| da Camara, CC | 1 |
| Lane, TW | 1 |
| Gross, MH | 1 |
| Fulkerson, WJ | 1 |
| Moore, JO | 1 |
3 reviews available for dantrolene and Catatonic Rigidity
| Article | Year |
|---|---|
Malignant hyperthermia.
Topics: Adult; Arrhythmias, Cardiac; Biopsy; Calcium; Child; Child, Preschool; Creatine Kinase; Dantrolene; | 1983 |
Treatment of porcine malignant hyperthermia. A review based on experimental studies.
Topics: Animals; Blood Glucose; Body Temperature; Carbon Dioxide; Catecholamines; Chlorpromazine; Dantrolene | 1975 |
Neuroleptic malignant syndrome.
Topics: Adult; Amantadine; Animals; Body Temperature; Bromocriptine; Dantrolene; Diagnosis, Differential; Fe | 1986 |
24 other studies available for dantrolene and Catatonic Rigidity
| Article | Year |
|---|---|
The severity of sevoflurane-induced malignant hyperthermia.
Topics: Adolescent; Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Body Temperature; Child, Prescho | 2012 |
[Masseter muscle rigidity after suxamethonium during induction and postoperative abortive malignant hyperthermia in a patient with esophageal achalasia].
Topics: Adult; Anesthesia, Epidural; Anesthesia, Intravenous; Dantrolene; Esophageal Achalasia; Humans; Infu | 2004 |
Video of dantrolene effectiveness on neuroleptic malignant syndrome associated muscular rigidity and tremor.
Topics: Aged; Dantrolene; Humans; Muscle Relaxants, Central; Muscle Rigidity; Neuroleptic Malignant Syndrome | 2007 |
Treatment of neuroleptic malignant syndrome with dantrolene.
Topics: Adult; Bipolar Disorder; Dantrolene; Haloperidol; Humans; Male; Malignant Hyperthermia; Muscle Rigid | 1982 |
Treatment of neuroleptic malignant syndrome with dantrolene.
Topics: Central Nervous System Diseases; Dantrolene; Diagnosis, Differential; Humans; Malignant Hyperthermia | 1982 |
Neuroleptic malignant syndrome.
Topics: Antipsychotic Agents; Dantrolene; Fever; Humans; Muscle Rigidity; Syndrome | 1984 |
The neuroleptic malignant syndrome. A priority system.
Topics: Amantadine; Antipsychotic Agents; Basal Ganglia Diseases; Bromocriptine; Consciousness Disorders; Da | 1984 |
Treating neuroleptic malignant syndrome.
Topics: Amantadine; Antipsychotic Agents; Bromocriptine; Dantrolene; Fever; Humans; Muscle Rigidity | 1984 |
Malignant hyperthermia.
Topics: Acidosis; Bicarbonates; Calcium; Creatine Kinase; Dantrolene; Diuretics; Fever; Humans; Malignant Hy | 1982 |
Beneficial effects of dantrolene in the treatment of neuroleptic malignant syndrome: a report of two cases.
Topics: Adolescent; Adult; Basal Ganglia Diseases; Dantrolene; Fever; Haloperidol; Humans; Male; Muscle Rigi | 1983 |
[A comparison of the effects of baclofen and some other muscle relaxants on alpha-rigidity in rats].
Topics: Animals; Baclofen; Brain Ischemia; Chlordiazepoxide; Dantrolene; Decerebrate State; Diazepam; Male; | 1984 |
Neuroleptic malignant syndrome: response to dantrolene sodium.
Topics: Dantrolene; Fever; Haloperidol; Humans; Male; Middle Aged; Muscle Rigidity; Syndrome | 1983 |
[Neuroleptic malignant syndrome. Beneficial effects of dantrolene on hyperthermia and hypertonia (author's transl)].
Topics: Adolescent; Basal Ganglia Diseases; Calcium; Dantrolene; Fever; Haloperidol; Humans; Male; Malignant | 1982 |
Neuroleptic malignant syndrome and clozapine.
Topics: Adult; Antipsychotic Agents; Bromocriptine; Clozapine; Dantrolene; Diagnosis, Differential; Fever; H | 1993 |
Development of an animal model for neuroleptic malignant syndrome: heat-exposed rabbits with haloperidol and atropine administration exhibit increased muscle activity, hyperthermia, and high serum creatine phosphokinase level.
Topics: Animals; Antipsychotic Agents; Atropine; Body Temperature Regulation; Cholinergic Antagonists; Creat | 1996 |
Antagonism of suxamethonium-induced jaw muscle contracture in rats.
Topics: Animals; Dantrolene; Male; Malignant Hyperthermia; Masseter Muscle; Muscle Relaxants, Central; Muscl | 1997 |
[Rigidity abolished by intravenous dantrolene in a patient with Parkinson's disease under spinal anesthesia].
Topics: Aged; Anesthesia, Spinal; Dantrolene; Female; Femoral Fractures; Humans; Muscle Rigidity; Parkinson | 1992 |
Neuroleptic malignant syndrome.
Topics: Biomarkers; Dantrolene; Female; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Muscle Ri | 1992 |
Diagnosing and treating neuroleptic malignant syndrome.
Topics: Antipsychotic Agents; Bromocriptine; Creatine Kinase; Dantrolene; Humans; Muscle Rigidity; Neurolept | 1986 |
Rigidity and fever in two psychotic patients.
Topics: Adult; Antipsychotic Agents; Bromocriptine; Dantrolene; Fever; Humans; Male; Muscle Rigidity; Neurol | 1986 |
Dantrolene sodium for treatment of carbon monoxide poisoning.
Topics: Adult; Carbon Monoxide Poisoning; Dantrolene; Female; Humans; Muscle Rigidity | 1988 |
Reversal of prolonged postoperative muscle rigidity by dantrolene: a case report.
Topics: Adolescent; Anesthesia, General; Anesthesia, Inhalation; Dantrolene; Halothane; Humans; Male; Muscle | 1988 |
Dantrolene for amphotericin B-induced rigors.
Topics: Adult; Amphotericin B; Dantrolene; Humans; Male; Muscle Rigidity | 1987 |
Prevention of amphotericin B-induced rigors by dantrolene.
Topics: Adult; Amphotericin B; Dantrolene; Female; Humans; Male; Middle Aged; Muscle Rigidity | 1986 |