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dantrolene and Cardiovascular Stroke

dantrolene has been researched along with Cardiovascular Stroke in 8 studies

Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.

Research Excerpts

ExcerptRelevanceReference
"Dantrolene was reported to suppress ventricular fibrillation (VF) in failing hearts with acute myocardial infarction, but its antiarrhythmic efficacy in regional ischemia-reperfusion (IR) hearts remains debatable."7.81Effects of dantrolene on arrhythmogenicity in isolated regional ischemia-reperfusion rabbit hearts with or without pacing-induced heart failure. ( Chang, PC; Chou, CC; Lee, HL; Wen, MS; Wo, HT; Yeh, SJ, 2015)
"Dantrolene prevents arrhythmogenic Ca(2+) release during heart failure (HF)."7.80Dantrolene suppresses ventricular ectopy and arrhythmogenicity with acute myocardial infarction in a langendorff-perfused pacing-induced heart failure rabbit model. ( Chang, PC; Chou, CC; Lee, HL; Wen, MS; Wo, HT; Wu, D; Yeh, SJ, 2014)
"Dantrolene was reported to suppress ventricular fibrillation (VF) in failing hearts with acute myocardial infarction, but its antiarrhythmic efficacy in regional ischemia-reperfusion (IR) hearts remains debatable."3.81Effects of dantrolene on arrhythmogenicity in isolated regional ischemia-reperfusion rabbit hearts with or without pacing-induced heart failure. ( Chang, PC; Chou, CC; Lee, HL; Wen, MS; Wo, HT; Yeh, SJ, 2015)
"Dantrolene prevents arrhythmogenic Ca(2+) release during heart failure (HF)."3.80Dantrolene suppresses ventricular ectopy and arrhythmogenicity with acute myocardial infarction in a langendorff-perfused pacing-induced heart failure rabbit model. ( Chang, PC; Chou, CC; Lee, HL; Wen, MS; Wo, HT; Wu, D; Yeh, SJ, 2014)
"Dantrolene-treated rats with myocardial infarction were placed into two different dosage groups."1.32Dantrolene: effects on abnormal intracellular Ca(2+) handling and inotropy in postinfarcted rat myocardium. ( Feng, X; Malek, S; Meissner, A; Min, JY; Morgan, JP; Simon, R; Wang, J; Wang, JF, 2003)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's1 (12.50)18.2507
2000's2 (25.00)29.6817
2010's2 (25.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Fujii, S1
Kobayashi, S1
Chang, Y1
Nawata, J1
Yoshitomi, R1
Tanaka, S1
Kohno, M1
Nakamura, Y1
Ishiguchi, H1
Suetomi, T1
Uchinoumi, H1
Oda, T1
Okuda, S1
Okamura, T1
Yamamoto, T1
Yano, M1
Chou, CC2
Wen, MS2
Lee, HL2
Chang, PC2
Wo, HT2
Yeh, SJ2
Wu, D1
Min, JY1
Meissner, A1
Feng, X1
Wang, J1
Malek, S1
Wang, JF1
Simon, R1
Morgan, JP1
Acikel, M1
Buyukokuroglu, ME1
Erdogan, F1
Aksoy, H1
Bozkurt, E1
Senocak, H1
Parr, MJ1
Craft, TM1
Adnet, P1
Krivosic-Horber, R1
Sahn, SA1

Reviews

2 reviews available for dantrolene and Cardiovascular Stroke

ArticleYear
[Calcium inhibitors and anesthesia].
    Annales francaises d'anesthesie et de reanimation, 1988, Volume: 7, Issue:6

    Topics: Analgesics; Anesthesia, General; Anesthetics; Arrhythmias, Cardiac; Brain Ischemia; Calcium Channel

1988
Immunologic diseases of the pleura.
    Clinics in chest medicine, 1985, Volume: 6, Issue:1

    Topics: Adult; Aged; Bromocriptine; Cardiac Surgical Procedures; Collagen Diseases; Dantrolene; Female; Gran

1985

Other Studies

6 other studies available for dantrolene and Cardiovascular Stroke

ArticleYear
RyR2-targeting therapy prevents left ventricular remodeling and ventricular tachycardia in post-infarction heart failure.
    Journal of molecular and cellular cardiology, 2023, Volume: 178

    Topics: Animals; Arrhythmias, Cardiac; Calmodulin; Dantrolene; Heart Failure; Mice; Myocardial Infarction; M

2023
Dantrolene suppresses ventricular ectopy and arrhythmogenicity with acute myocardial infarction in a langendorff-perfused pacing-induced heart failure rabbit model.
    Journal of cardiovascular electrophysiology, 2014, Volume: 25, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Cardiac Pacing, Artificial; Coronary

2014
Effects of dantrolene on arrhythmogenicity in isolated regional ischemia-reperfusion rabbit hearts with or without pacing-induced heart failure.
    BioMed research international, 2015, Volume: 2015

    Topics: Animals; Anti-Arrhythmia Agents; Dantrolene; Heart; Heart Failure; Heart Ventricles; Myocardial Infa

2015
Dantrolene: effects on abnormal intracellular Ca(2+) handling and inotropy in postinfarcted rat myocardium.
    European journal of pharmacology, 2003, Jun-13, Volume: 471, Issue:1

    Topics: Animals; Blotting, Western; Calcium; Calcium-Binding Proteins; Calcium-Transporting ATPases; Cycloph

2003
Protective effects of dantrolene against myocardial injury induced by isoproterenol in rats: biochemical and histological findings.
    International journal of cardiology, 2005, Feb-28, Volume: 98, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Dantrolene; Disease Models, Animal; Heart; Isoproterenol; Male; M

2005
The management of acute poisoning.
    British journal of anaesthesia, 1993, Volume: 71, Issue:4

    Topics: Dantrolene; Fever; Humans; Myocardial Infarction; Poisoning; Unconsciousness

1993