dantrolene has been researched along with Batten Turner Congenital Myopathy in 2 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 3 year, 10 month old male with myotonia congenita (Thomsen's disease) was placed on dantrolene sodium, which successfully abolished the myotonic phenomenon." | 1.28 | Successful dantrolene sodium treatment of a patient with myotonia congenita (Thomsen's disease). ( Komori, H; Matsuishi, T; Ohtaki, E; Yamaguchi, Y, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Magyar, ZÉ | 1 |
| Hevesi, J | 1 |
| Groom, L | 1 |
| Dirksen, RT | 1 |
| Almássy, J | 1 |
| Ohtaki, E | 1 |
| Komori, H | 1 |
| Yamaguchi, Y | 1 |
| Matsuishi, T | 1 |
2 other studies available for dantrolene and Batten Turner Congenital Myopathy
| Article | Year |
|---|---|
Function of a mutant ryanodine receptor (T4709M) linked to congenital myopathy.
Topics: Adenosine Triphosphate; Animals; Cytoplasm; Dantrolene; Mice; Muscular Diseases; Myotonia Congenita; | 2023 |
Successful dantrolene sodium treatment of a patient with myotonia congenita (Thomsen's disease).
Topics: Child, Preschool; Dantrolene; Electromyography; Humans; Male; Muscles; Myotonia Congenita; Remission | 1991 |