dantrolene has been researched along with Basal Ganglia Diseases in 20 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Basal Ganglia Diseases: Diseases of the BASAL GANGLIA including the PUTAMEN; GLOBUS PALLIDUS; claustrum; AMYGDALA; and CAUDATE NUCLEUS. DYSKINESIAS (most notably involuntary movements and alterations of the rate of movement) represent the primary clinical manifestations of these disorders. Common etiologies include CEREBROVASCULAR DISORDERS; NEURODEGENERATIVE DISEASES; and CRANIOCEREBRAL TRAUMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Malignant syndrome is a disease characterized by high fever, extrapyramidal syndrome and dysautonomia recognized during or at the time of stopping administration of antipsychotic medication and it is the most severe and lethal side effect of antipsychotic medication." | 5.30 | [A case of malignant syndrome triggered by the use of haloperidol and chrorpromazine]. ( Fujimoto, K; Konishi, K; Kubota, M; Ogawa, H, 1997) |
| "A case of neuroleptic malignant syndrome (NMS) with an abrupt onset was terminated quickly with i." | 5.27 | Resolution of neuroleptic malignant syndrome with dantrolene sodium: case report. ( Jaffe, JH; Khan, A; Morrison, B; Nelson, WH, 1985) |
| "We present the case of a 35-year-old man who developed symptoms of the neuroleptic malignant syndrome (NMS) after taking prescribed, moderately high, therapeutic doses of haloperidol." | 3.67 | Neuroleptic malignant syndrome. ( Lucid, EJ; Martin, ML; Walker, RW, 1985) |
| "A patient with chronic schizophrenia treated with fluphenazine developed neuroleptic malignant syndrome, characterized by fever, obtundation, rigidity, and tremulousness." | 3.66 | Neuroleptic malignant syndrome: successful treatment with dantrolene and bromocriptine. ( Adler, S; Coyle, J; Granato, JE; Karim, AH; Krumholz, A; Ringel, A; Stern, BJ, 1983) |
| " Muscle rigidity was not affected by etybenzatropine or diazepam, but dantrolene, a direct-acting skeletal muscle relaxant, provided muscle relaxation with a concomitant decrease of fever and serum creatine kinase." | 3.66 | Beneficial effects of dantrolene in the treatment of neuroleptic malignant syndrome: a report of two cases. ( Bismuth, C; Conso, F; de Rohan-Chabot, P; Elkharrat, D; Gajdos, P; Goulon, M, 1983) |
| " switching to a low-potency or an atypical antipsychotic, lowering the dosage or discontinuing the NL, and adding a drug effective in treating EPS." | 2.40 | Algorithms for the treatment of acute side effects induced by neuroleptics. ( Koyama, T; Kusumi, I, 1999) |
| "Neuroleptic malignant syndrome is a rare but serious adverse effect of antipsychotic medication." | 2.37 | Neuroleptic malignant syndrome. ( Levenson, JL, 1985) |
| "On arrival, the Japan coma scale, pulse, respiratory rate, body temperature, and Sp(O2) were 300, 114 beats x min(-1), 26 breaths x min(-1), 39." | 1.38 | [Comatose patient with neuroleptic malignant syndrome brought by ambulance]. ( Kuroda, Y; Takinami, Y, 2012) |
| "Malignant syndrome is a disease characterized by high fever, extrapyramidal syndrome and dysautonomia recognized during or at the time of stopping administration of antipsychotic medication and it is the most severe and lethal side effect of antipsychotic medication." | 1.30 | [A case of malignant syndrome triggered by the use of haloperidol and chrorpromazine]. ( Fujimoto, K; Konishi, K; Kubota, M; Ogawa, H, 1997) |
| "Dantrolene also has been utilized successfully in NMS on the hypothesis that the syndrome is similar to anesthetic-induced malignant hyperthermia." | 1.27 | Therapy of syndrome malin. ( Conner, CS, 1983) |
| "A case of neuroleptic malignant syndrome (NMS) with an abrupt onset was terminated quickly with i." | 1.27 | Resolution of neuroleptic malignant syndrome with dantrolene sodium: case report. ( Jaffe, JH; Khan, A; Morrison, B; Nelson, WH, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (85.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takinami, Y | 1 |
| Kuroda, Y | 1 |
| Henderson, VW | 1 |
| Conner, CS | 1 |
| Neppe, VM | 1 |
| Bismuth, C | 3 |
| de Rohan-Chabot, P | 2 |
| Goulon, M | 3 |
| Raphael, JC | 1 |
| Konikoff, F | 1 |
| Kuritzky, A | 1 |
| Jerushalmi, Y | 1 |
| Theodor, E | 1 |
| Gómez, EA | 1 |
| Granato, JE | 1 |
| Stern, BJ | 1 |
| Ringel, A | 1 |
| Karim, AH | 1 |
| Krumholz, A | 1 |
| Coyle, J | 1 |
| Adler, S | 1 |
| Elkharrat, D | 2 |
| Gajdos, P | 1 |
| Conso, F | 2 |
| de Rohan Chabot, P | 1 |
| Konishi, K | 1 |
| Fujimoto, K | 1 |
| Kubota, M | 1 |
| Ogawa, H | 1 |
| Kusumi, I | 1 |
| Koyama, T | 1 |
| Fricchione, GL | 1 |
| Levenson, JL | 1 |
| Knight, ME | 1 |
| Roberts, RJ | 1 |
| Guzé, BH | 1 |
| Baxter, LR | 1 |
| Khan, A | 1 |
| Jaffe, JH | 1 |
| Nelson, WH | 1 |
| Morrison, B | 1 |
| Rosse, R | 1 |
| Ciolino, C | 1 |
| Schulte-Sasse, U | 1 |
| Komar, K | 1 |
| Eberlein, HJ | 1 |
| Martin, ML | 1 |
| Lucid, EJ | 1 |
| Walker, RW | 1 |
4 reviews available for dantrolene and Basal Ganglia Diseases
| Article | Year |
|---|---|
Algorithms for the treatment of acute side effects induced by neuroleptics.
Topics: Algorithms; Antiparkinson Agents; Antipsychotic Agents; Basal Ganglia Diseases; Bromocriptine; Dantr | 1999 |
Neuroleptic malignant syndrome.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Bromocriptine; Child; Dantrol | 1985 |
Phenothiazine and butyrophenone intoxication in children.
Topics: Absorption; Adolescent; Basal Ganglia Diseases; Benztropine; Butyrophenones; Cardiovascular System; | 1986 |
Current concepts. Neuroleptic malignant syndrome.
Topics: Amantadine; Basal Ganglia Diseases; Bromocriptine; Catatonia; Dantrolene; Diagnosis, Differential; D | 1985 |
16 other studies available for dantrolene and Basal Ganglia Diseases
| Article | Year |
|---|---|
[Comatose patient with neuroleptic malignant syndrome brought by ambulance].
Topics: Adult; Ambulances; Basal Ganglia Diseases; Chlorpromazine; Coma; Dantrolene; Drug Overdose; Female; | 2012 |
Questions about dantrolene for neuroleptic malignant syndrome.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Dantrolene; Fever; Humans; Malignant Hyperthermia | 1983 |
Therapy of syndrome malin.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Dantrolene; Fever; Humans; Syndrome | 1983 |
The neuroleptic malignant syndrome. A priority system.
Topics: Amantadine; Antipsychotic Agents; Basal Ganglia Diseases; Bromocriptine; Consciousness Disorders; Da | 1984 |
Dantrolene--a new therapeutic approach to the neuroleptic malignant syndrome.
Topics: Adolescent; Adult; Basal Ganglia Diseases; Dantrolene; Haloperidol; Heat Exhaustion; Humans; Hyperte | 1984 |
Neuroleptic malignant syndrome induced by a single injection of haloperidol.
Topics: Basal Ganglia Diseases; Dantrolene; Female; Haloperidol; Humans; Middle Aged; Neuroleptic Malignant | 1984 |
[Extrapyramidal reactions and neuroleptic malignant syndrome].
Topics: Adult; Amantadine; Basal Ganglia Diseases; Dantrolene; Haloperidol; Humans; Male; Neuroleptic Malign | 1984 |
Neuroleptic malignant syndrome: successful treatment with dantrolene and bromocriptine.
Topics: Adult; Basal Ganglia Diseases; Bromocriptine; Dantrolene; Drug Therapy, Combination; Fluphenazine; H | 1983 |
Beneficial effects of dantrolene in the treatment of neuroleptic malignant syndrome: a report of two cases.
Topics: Adolescent; Adult; Basal Ganglia Diseases; Dantrolene; Fever; Haloperidol; Humans; Male; Muscle Rigi | 1983 |
[Neuroleptic malignant syndrome. Beneficial effects of dantrolene on hyperthermia and hypertonia (author's transl)].
Topics: Adolescent; Basal Ganglia Diseases; Calcium; Dantrolene; Fever; Haloperidol; Humans; Male; Malignant | 1982 |
[A case of malignant syndrome triggered by the use of haloperidol and chrorpromazine].
Topics: Adult; Antipsychotic Agents; Anxiety; Autonomic Nervous System Diseases; Basal Ganglia Diseases; Chl | 1997 |
Neuroleptic catatonia and its relationship to psychogenic catatonia.
Topics: Anti-Anxiety Agents; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Brain; Catatonia | 1985 |
Resolution of neuroleptic malignant syndrome with dantrolene sodium: case report.
Topics: Basal Ganglia Diseases; Bipolar Disorder; Dantrolene; Drug Therapy, Combination; Haloperidol; Humans | 1985 |
Dopamine agonists and neuroleptic malignant syndrome.
Topics: Alzheimer Disease; Amantadine; Basal Ganglia Diseases; Bromocriptine; Dantrolene; Humans; Male; Midd | 1985 |
[Dantrolene in the treatment of life-threatening psychiatric disease pictures. A contribution to the therapy of the malignant neuroleptic syndrome and acute febrile catatonia].
Topics: Adult; Basal Ganglia Diseases; Dantrolene; Diagnosis, Differential; Fever; Humans; Male; Malignant H | 1985 |
Neuroleptic malignant syndrome.
Topics: Adult; Basal Ganglia Diseases; Bromocriptine; Dantrolene; Diagnosis, Differential; Haloperidol; Heat | 1985 |