dantrolene has been researched along with Alloxan Diabetes in 2 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dose-response curves for the 5-HT-induced contraction (from 0." | 1.62 | The combination of dantrolene and nimodipine effectively reduces 5-HT-induced vasospasms in diabetic rats. ( Crespo, MJ; García, L; Morales, M; Román, M, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Román, M | 2 |
| Ramírez, JM | 1 |
| Morales, M | 2 |
| Crespo, MJ | 2 |
| García, L | 1 |
2 other studies available for dantrolene and Alloxan Diabetes
| Article | Year |
|---|---|
Significant reduction of vascular reactivity with dantrolene and nimodipine in diabetic rats: a potential approach to cerebral vasospasm management in diabetes.
Topics: Acetylcholine; Animals; Dantrolene; Diabetes Mellitus, Experimental; Dose-Response Relationship, Dru | 2020 |
The combination of dantrolene and nimodipine effectively reduces 5-HT-induced vasospasms in diabetic rats.
Topics: Animals; Calcium Channel Blockers; Dantrolene; Diabetes Mellitus, Experimental; Drug Therapy, Combin | 2021 |