Page last updated: 2024-10-25

dantrolene and Allodynia

dantrolene has been researched along with Allodynia in 3 studies

Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.

Research Excerpts

ExcerptRelevanceReference
"Paclitaxel treatment resulted in a peripheral neuropathy that affected the two hindpaws."1.35Different antinociceptive effects of botulinum toxin type A in inflammatory and peripheral polyneuropathic rat models. ( Auguet, M; Chabrier, PE; Favre-Guilmard, C, 2009)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Favre-Guilmard, C1
Auguet, M1
Chabrier, PE1
Gemes, G1
Rigaud, M1
Weyker, PD1
Abram, SE1
Weihrauch, D1
Poroli, M1
Zoga, V1
Hogan, QH2
Tang, Q1
Bangaru, ML1
Kostic, S1
Pan, B1
Wu, HE1
Koopmeiners, AS1
Yu, H1
Fischer, GJ1
McCallum, JB1
Kwok, WM1
Hudmon, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Botulinum Toxin A for the Treatment of Chemotherapy Induced Peripheral Neuropathy[NCT03571334]Phase 240 participants (Anticipated)Interventional2020-07-08Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

3 other studies available for dantrolene and Allodynia

ArticleYear
Different antinociceptive effects of botulinum toxin type A in inflammatory and peripheral polyneuropathic rat models.
    European journal of pharmacology, 2009, Sep-01, Volume: 617, Issue:1-3

    Topics: Analgesics; Animals; Botulinum Toxins, Type A; Carrageenan; Dantrolene; Disease Models, Animal; Edem

2009
Depletion of calcium stores in injured sensory neurons: anatomic and functional correlates.
    Anesthesiology, 2009, Volume: 111, Issue:2

    Topics: Animals; Boron Compounds; Calbindin 2; Calcium; Calcium Signaling; Cytoplasm; Dantrolene; Electrophy

2009
Ca²⁺-dependent regulation of Ca²⁺ currents in rat primary afferent neurons: role of CaMKII and the effect of injury.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Aug-22, Volume: 32, Issue:34

    Topics: Analysis of Variance; Animals; Biophysical Phenomena; Biophysics; Calcium; Calcium Channel Blockers;

2012