dantrolene has been researched along with Allodynia in 3 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Paclitaxel treatment resulted in a peripheral neuropathy that affected the two hindpaws." | 1.35 | Different antinociceptive effects of botulinum toxin type A in inflammatory and peripheral polyneuropathic rat models. ( Auguet, M; Chabrier, PE; Favre-Guilmard, C, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Favre-Guilmard, C | 1 |
| Auguet, M | 1 |
| Chabrier, PE | 1 |
| Gemes, G | 1 |
| Rigaud, M | 1 |
| Weyker, PD | 1 |
| Abram, SE | 1 |
| Weihrauch, D | 1 |
| Poroli, M | 1 |
| Zoga, V | 1 |
| Hogan, QH | 2 |
| Tang, Q | 1 |
| Bangaru, ML | 1 |
| Kostic, S | 1 |
| Pan, B | 1 |
| Wu, HE | 1 |
| Koopmeiners, AS | 1 |
| Yu, H | 1 |
| Fischer, GJ | 1 |
| McCallum, JB | 1 |
| Kwok, WM | 1 |
| Hudmon, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Botulinum Toxin A for the Treatment of Chemotherapy Induced Peripheral Neuropathy[NCT03571334] | Phase 2 | 40 participants (Anticipated) | Interventional | 2020-07-08 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for dantrolene and Allodynia
| Article | Year |
|---|---|
Different antinociceptive effects of botulinum toxin type A in inflammatory and peripheral polyneuropathic rat models.
Topics: Analgesics; Animals; Botulinum Toxins, Type A; Carrageenan; Dantrolene; Disease Models, Animal; Edem | 2009 |
Depletion of calcium stores in injured sensory neurons: anatomic and functional correlates.
Topics: Animals; Boron Compounds; Calbindin 2; Calcium; Calcium Signaling; Cytoplasm; Dantrolene; Electrophy | 2009 |
Ca²⁺-dependent regulation of Ca²⁺ currents in rat primary afferent neurons: role of CaMKII and the effect of injury.
Topics: Analysis of Variance; Animals; Biophysical Phenomena; Biophysics; Calcium; Calcium Channel Blockers; | 2012 |