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dantrolene and Alcoholism

dantrolene has been researched along with Alcoholism in 5 studies

Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.

Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)

Research Excerpts

ExcerptRelevanceReference
"In the alcohol dependence group, median duration of baclofen treatment was 143."1.40Baclofen for alcohol dependence in France: incidence of treated patients and prescription patterns--a cohort study. ( Dupouy, J; Fournier, JP; Jouanjus, É; Lapeyre-Mestre, M; Oustric, S; Palmaro, A; Poutrain, JC, 2014)
"Alcohol abuse is a leading cause of pancreatitis, accounting for 30% of acute cases and 70-90% of chronic cases, yet the mechanisms leading to alcohol-associated pancreatic injury are unclear."1.37Ethanol enhances carbachol-induced protease activation and accelerates Ca2+ waves in isolated rat pancreatic acini. ( Ahmad, A; Husain, SZ; Luo, Y; Mahmood, SM; Muili, K; Orabi, AI; Reed, A; Shah, AU, 2011)
"Ever since, the concept of catatonia has been the focus of debate, a major point of discussion being its nosological status."1.34Catatonia and neuroleptic malignant syndrome: two sides of a coin? ( Santens, P; Vancaester, E, 2007)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dupouy, J1
Fournier, JP1
Jouanjus, É1
Palmaro, A1
Poutrain, JC1
Oustric, S1
Lapeyre-Mestre, M1
Orabi, AI1
Shah, AU1
Muili, K1
Luo, Y1
Mahmood, SM1
Ahmad, A1
Reed, A1
Husain, SZ1
Kurokawa, K1
Mizuno, K1
Ohkuma, S1
Vancaester, E1
Santens, P1
Materson, BJ1
Preston, RA1

Other Studies

5 other studies available for dantrolene and Alcoholism

ArticleYear
Baclofen for alcohol dependence in France: incidence of treated patients and prescription patterns--a cohort study.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:2

    Topics: Alcoholism; Baclofen; Dantrolene; Europe; Female; France; Hospitalization; Humans; Incidence; Male;

2014
Ethanol enhances carbachol-induced protease activation and accelerates Ca2+ waves in isolated rat pancreatic acini.
    The Journal of biological chemistry, 2011, Apr-22, Volume: 286, Issue:16

    Topics: Alcoholism; Animals; Calcium; Carbachol; Chymotrypsin; Dantrolene; Disease Models, Animal; Ethanol;

2011
Dopamine D1 receptor signaling system regulates ryanodine receptor expression in ethanol physical dependence.
    Alcoholism, clinical and experimental research, 2013, Volume: 37, Issue:5

    Topics: Alcoholism; Animals; Benzazepines; Blotting, Western; Brain; Central Nervous System Depressants; Dan

2013
Catatonia and neuroleptic malignant syndrome: two sides of a coin?
    Acta neurologica Belgica, 2007, Volume: 107, Issue:2

    Topics: Adult; Aged; Alcoholism; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Brain Injuries; Br

2007
Myoglobinuria versus hemoglobinuria.
    Hospital practice (Office ed.), 1988, Oct-30, Volume: 23, Issue:10A

    Topics: Acute Kidney Injury; Alcoholism; Biopsy; Creatine Kinase; Dantrolene; Diagnosis, Differential; Hemog

1988