dantrolene has been researched along with Adverse Drug Event in 3 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dantrolene median dose was 50 (25-400) and 200 (25-400) mg·day -1 in responders and nonresponders, respectively." | 1.91 | Oral Dantrolene for Myopathic Symptoms in Malignant Hyperthermia-Susceptible Patients: A 25-Year Retrospective Cohort Study of Adverse Effects and Tolerability. ( Ibarra Moreno, CA; Jungbluth, H; Kraeva, N; Riazi, S; Voermans, NC; Zvaritch, E, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Ibarra Moreno, CA | 1 |
| Kraeva, N | 2 |
| Zvaritch, E | 1 |
| Jungbluth, H | 1 |
| Voermans, NC | 1 |
| Riazi, S | 2 |
| Timmins, MA | 1 |
| Rosenberg, H | 1 |
| Larach, MG | 1 |
| Sterling, C | 1 |
| James, OF | 1 |
1 review available for dantrolene and Adverse Drug Event
| Article | Year |
|---|---|
Drugs and the ageing liver.
Topics: Aged; Aging; Biotransformation; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Syst | 1985 |
2 other studies available for dantrolene and Adverse Drug Event
| Article | Year |
|---|---|
Oral Dantrolene for Myopathic Symptoms in Malignant Hyperthermia-Susceptible Patients: A 25-Year Retrospective Cohort Study of Adverse Effects and Tolerability.
Topics: Dantrolene; Drug-Related Side Effects and Adverse Reactions; Fatigue; Halothane; Humans; Malignant H | 2023 |
Malignant hyperthermia testing in probands without adverse anesthetic reaction.
Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Caffeine; Dantrolene; Drug-Related Side Effects an | 2015 |