dantrolene has been researched along with 2019 Novel Coronavirus Disease in 6 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dantrolene is a ryanodine receptor antagonist and is used as an anti-inflammatory agent." | 5.62 | Beneficial effects of dantrolene in the treatment of rhabdomyolysis as a potential late complication associated with COVID-19: a case report. ( Chiba, N; Kinoshita, K; Matsuzaki, M; Mawatari, T; Mizuochi, M; Sakurai, A, 2021) |
| "BACKGROUND Considering the ongoing coronavirus disease 2019 (COVID-19) pandemic, sufficient information about common and serious adverse events is needed to rapidly distribute COVID-19 vaccines worldwide." | 1.72 | Neuroleptic Malignant Syndrome with Adrenal Insufficiency After BNT162b2 COVID-19 Vaccination in a Man Taking Valproate: A Case Report. ( Kamiyama, T; Mizuno, T; Suzuki, A; Suzuki, M; Takahashi, R, 2022) |
| "Dantrolene is a ryanodine receptor antagonist and is used as an anti-inflammatory agent." | 1.62 | Beneficial effects of dantrolene in the treatment of rhabdomyolysis as a potential late complication associated with COVID-19: a case report. ( Chiba, N; Kinoshita, K; Matsuzaki, M; Mawatari, T; Mizuochi, M; Sakurai, A, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 6 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mizuno, T | 1 |
| Takahashi, R | 1 |
| Kamiyama, T | 1 |
| Suzuki, A | 1 |
| Suzuki, M | 1 |
| Alkazmi, L | 1 |
| Al-Kuraishy, HM | 1 |
| Al-Gareeb, AI | 1 |
| El-Bouseary, MM | 1 |
| Ahmed, EA | 1 |
| Batiha, GE | 1 |
| Kajani, R | 1 |
| Apramian, A | 1 |
| Vega, A | 1 |
| Ubhayakar, N | 1 |
| Xu, P | 1 |
| Liu, A | 1 |
| Jiang, B | 1 |
| Liang, S | 1 |
| Liang, G | 2 |
| Wei, H | 2 |
| Chiba, N | 1 |
| Matsuzaki, M | 1 |
| Mawatari, T | 1 |
| Mizuochi, M | 1 |
| Sakurai, A | 1 |
| Kinoshita, K | 1 |
| Vera, RM | 1 |
2 reviews available for dantrolene and 2019 Novel Coronavirus Disease
| Article | Year |
|---|---|
Dantrolene and ryanodine receptors in COVID-19: The daunting task and neglected warden.
Topics: COVID-19; Dantrolene; Humans; Receptors, N-Methyl-D-Aspartate; Ryanodine Receptor Calcium Release Ch | 2023 |
Dantrolene repurposed to treat sepsis or septic shock and COVID-19 patients.
Topics: Calcium; Calcium Channel Blockers; COVID-19; COVID-19 Drug Treatment; Dantrolene; Drug Repositioning | 2021 |
4 other studies available for dantrolene and 2019 Novel Coronavirus Disease
| Article | Year |
|---|---|
Neuroleptic Malignant Syndrome with Adrenal Insufficiency After BNT162b2 COVID-19 Vaccination in a Man Taking Valproate: A Case Report.
Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; BNT162 Vaccine; Bromocriptine; COVID-19; Dantrol | 2022 |
Neuroleptic malignant syndrome in a COVID-19 patient.
Topics: Acute Kidney Injury; Antipsychotic Agents; Betacoronavirus; Bromocriptine; C-Reactive Protein; Coron | 2020 |
Could dantrolene be explored as a repurposed drug to treat COVID-19 patients by restoring intracellular calcium homeostasis?
Topics: Calcium; COVID-19; COVID-19 Drug Treatment; Dantrolene; Drug Repositioning; Homeostasis; Humans; Mus | 2020 |
Beneficial effects of dantrolene in the treatment of rhabdomyolysis as a potential late complication associated with COVID-19: a case report.
Topics: Adult; COVID-19; Dantrolene; Humans; Male; Malignant Hyperthermia; Muscle Relaxants, Central; Rhabdo | 2021 |