Compounds > danazol
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danazol and Chemical and Drug Induced Liver Injury

danazol has been researched along with Chemical and Drug Induced Liver Injury in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19908 (32.00)18.7374
1990's4 (16.00)18.2507
2000's2 (8.00)29.6817
2010's11 (44.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Calado, RT; Clé, DV1
Chuhjo, T; Nakao, S; Omine, M; Yamazaki, H1
Kusuda, M; Nagata, Y; Nakamura, G1
Horie, T; Morimoto, K; Sakuma, A; Sawada, U; Tsuboi, I1
Durán Pérez-Navarro, MA; Juarez Ucelay, F; Marcos Sánchez, F1
Alvarez Puebla, MJ; Estrada Rodríguez, JL; Gozalo Reques, F; Jorquera Plaza, F1
Colella, F; Di Virgilio, D; Grandioso, P; Lancia, A; Nicolella, U1
Amor, B; Awada, H; Baetz, A; Chevalier, X1
Fujimori, R; Nishii, O; Okamura, T; Takeuchi, T; Yaginuma, T1
Boue, F; Coffin, B; Delfraissy, JF1
Ikeda, Y; Ishii, H; Kanai, K; Matsuda, H; Matsumoto, M; Mizushima, N; Morioka, S; Nakajima, T; Tamakoshi, K; Terao, T1
Iwashita, S; Ohsawa, T1
Boylen, AL; Kasper, CK1
Dollberg, L; Hershko, C; Nesher, G; Zimran, A1
Ikeda, Y; Kanai, K; Matsuda, H; Matsumoto, M; Mizushima, N; Morioka, S; Nakajima, T; Tamakoshi, K; Terao, T1

Reviews

2 review(s) available for danazol and Chemical and Drug Induced Liver Injury

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Treatment of inherited bone marrow failure syndromes beyond transplantation.
    Hematology. American Society of Hematology. Education Program, 2017, 12-08, Volume: 2017, Issue:1

    Topics: Androgens; Bone Marrow Diseases; Chemical and Drug Induced Liver Injury; Danazol; Female; Genetic Diseases, Inborn; Genetic Therapy; Humans; Leucine; Oxymetholone; Quercetin; Stem Cell Transplantation; Syndrome; Virilism

2017

Trials

1 trial(s) available for danazol and Chemical and Drug Induced Liver Injury

ArticleYear
Danazol therapy for aplastic anemia refractory to immunosuppressive therapy.
    American journal of hematology, 2008, Volume: 83, Issue:5

    Topics: Adult; Aged; Anemia, Aplastic; Blood Transfusion; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Danazol; Drug Resistance; Female; Hemoglobinuria, Paroxysmal; Humans; Immunosuppressive Agents; Male; Middle Aged; Prospective Studies; Treatment Outcome

2008

Other Studies

22 other study(ies) available for danazol and Chemical and Drug Induced Liver Injury

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index

2014
Therapeutic effect and side effects of danazol in endometriosis.
    Asia-Oceania journal of obstetrics and gynaecology, 1982, Volume: 8, Issue:3

    Topics: Adult; Chemical and Drug Induced Liver Injury; Danazol; Endometriosis; Female; Follow-Up Studies; Humans; Infertility, Female; Pregnadienes; Pregnancy; Recurrence

1982
Liver damage after danazol and glucocorticoids for chronic idiopathic thrombocytopenic purpura (ITP)
    Internal medicine (Tokyo, Japan), 1995, Volume: 34, Issue:1

    Topics: Chemical and Drug Induced Liver Injury; Chronic Disease; Danazol; Endometriosis; Female; Glucocorticoids; Humans; Purpura, Thrombocytopenic, Idiopathic

1995
[Danazol and cholestatic hepatitis].
    Anales de medicina interna (Madrid, Spain : 1984), 1996, Volume: 13, Issue:4

    Topics: Anemia, Aplastic; Chemical and Drug Induced Liver Injury; Cholestasis; Danazol; Estrogen Antagonists; Female; Humans; Purpura, Thrombocytopenic

1996
[Danazol-induced hepatitis with functional deficit of the C1 inhibitor].
    Anales de medicina interna (Madrid, Spain : 1984), 2001, Volume: 18, Issue:11

    Topics: Adult; Chemical and Drug Induced Liver Injury; Complement C1 Inactivator Proteins; Complement C1 Inhibitor Protein; Danazol; Estrogen Antagonists; Humans; Male

2001
Hepatic damage after danazol treatment.
    The Italian journal of gastroenterology, 1991, Volume: 23, Issue:1

    Topics: Chemical and Drug Induced Liver Injury; Danazol; Female; Fibrocystic Breast Disease; Humans; Liver Diseases; Liver Function Tests; Middle Aged

1991
Danazol induced pancreatitis and hepatitis.
    Clinical rheumatology, 1990, Volume: 9, Issue:2

    Topics: Acetaminophen; Adult; Chemical and Drug Induced Liver Injury; Cimetidine; Danazol; Female; Humans; Lupus Erythematosus, Systemic; Pancreatitis; Pregnadienes

1990
Preventive effect of traditional herbal medicine, shosaiko-to, on danazol-induced hepatic damage.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1989, Volume: 29, Issue:4

    Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Danazol; Drugs, Chinese Herbal; Endometriosis; Female; Humans; Japan; L-Lactate Dehydrogenase; Liver Diseases; Medicine, East Asian Traditional; Middle Aged; Phytotherapy; Pregnadienes

1989
Danazol and cholestatic hepatitis.
    Annals of internal medicine, 1986, Volume: 105, Issue:1

    Topics: Aged; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Danazol; Female; Humans; Pregnadienes

1986
Fulminant hepatic failure associated with aplastic anaemia after treatment with danazol. Case report.
    British journal of obstetrics and gynaecology, 1986, Volume: 93, Issue:9

    Topics: Acute Disease; Adult; Anemia, Aplastic; Chemical and Drug Induced Liver Injury; Danazol; Dysmenorrhea; Female; Humans; Liver; Liver Diseases; Pregnadienes

1986
Hepatitis associated with danazol.
    Drug intelligence & clinical pharmacy, 1986, Volume: 20, Issue:11

    Topics: Adult; Chemical and Drug Induced Liver Injury; Danazol; Female; Humans; Pregnadienes

1986
Poor response to danazol in hemophilia.
    Blood, 1985, Volume: 65, Issue:1

    Topics: Adult; Chemical and Drug Induced Liver Injury; Danazol; Drug Evaluation; Factor VIII; Hemophilia A; Hemophilia B; Humans; Male; Pregnadienes

1985
Hepatosplenic peliosis after danazol and glucocorticoids for ITP.
    The New England journal of medicine, 1985, Jan-24, Volume: 312, Issue:4

    Topics: Aged; Chemical and Drug Induced Liver Injury; Danazol; Female; Glucocorticoids; Humans; Hydrocortisone; Peliosis Hepatis; Prednisone; Pregnadienes; Purpura; Purpura, Thrombocytopenic; Splenic Diseases

1985
[A case of fulminant hepatic failure followed by fatal aplastic anemia after administration of danazol].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1985, Volume: 82, Issue:9

    Topics: Adult; Anemia, Aplastic; Chemical and Drug Induced Liver Injury; Danazol; Endometriosis; Female; Humans; Pregnadienes

1985