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dan 2163 and Weight Gain

dan 2163 has been researched along with Weight Gain in 20 studies

Weight Gain: Increase in BODY WEIGHT over existing weight.

Research Excerpts

ExcerptRelevanceReference
"Amisulpride was more efficacious than aripiprazole or olanzapine for reducing the PANSS total scores in adults with schizophrenia-spectrum disorders."9.34Amisulpride, aripiprazole, and olanzapine in patients with schizophrenia-spectrum disorders (BeSt InTro): a pragmatic, rater-blind, semi-randomised trial. ( Alisauskiene, R; Anda, LG; Bartz-Johannessen, C; Berle, JØ; Bjarke, J; Fathian, F; Fleischhacker, WW; Hugdahl, K; Joa, I; Johnsen, E; Kjelby, E; Kroken, RA; Larsen, TK; Løberg, EM; Reitan, SK; Rettenbacher, M; Sinkeviciute, I; Skrede, S; Stabell, L; Steen, VM; Walla, B, 2020)
"We compared the efficacy of ziprasidone and amisulpride in the treatment of negative symptoms and overall psychopathology in subjects who had chronic schizophrenia with predominantly negative symptoms."9.12Ziprasidone and amisulpride effectively treat negative symptoms of schizophrenia: results of a 12-week, double-blind study. ( Murray, S; Olié, JP; Spina, E; Yang, R, 2006)
"To compare the efficacy and safety of amisulpride and olanzapine in subjects with schizophrenia and comorbid depression in a randomised double-blind trial."9.12A double-blind randomised comparative trial of amisulpride versus olanzapine for 2 months in the treatment of subjects with schizophrenia and comorbid depression. ( Douki, S; Vanelle, JM, 2006)
"Between 40% and 70% of people with treatment-resistant schizophrenia do not respond to clozapine, despite adequate blood levels."8.95Clozapine combined with different antipsychotic drugs for treatment-resistant schizophrenia. ( Barber, S; Cipriani, A; Corsi, M; Olotu, U, 2017)
"We compared stable patients with schizophrenia who were treated with either amisulpride or olanzapine in terms of symptomatic outcome, neurocognitive functioning, functionality, and subjective outcome."7.74Outcomes in schizophrenia outpatients treated with amisulpride or olanzapine. ( Bodner, T; Edlinger, M; Fleischhacker, WW; Hofer, A; Huber, R; Kemmler, G; Rettenbacher, MA; Sachs, G, 2007)
"Tremor and insomnia were more frequent with amisulpride, while olanzapine caused more weight gain and sedation."6.75Amisulpride versus olanzapine in the treatment of schizophrenia in Indian patients: randomized controlled trial. ( Bhowmick, S; Ghosh, M; Hazra, A, 2010)
"Amisulpride was more efficacious than aripiprazole or olanzapine for reducing the PANSS total scores in adults with schizophrenia-spectrum disorders."5.34Amisulpride, aripiprazole, and olanzapine in patients with schizophrenia-spectrum disorders (BeSt InTro): a pragmatic, rater-blind, semi-randomised trial. ( Alisauskiene, R; Anda, LG; Bartz-Johannessen, C; Berle, JØ; Bjarke, J; Fathian, F; Fleischhacker, WW; Hugdahl, K; Joa, I; Johnsen, E; Kjelby, E; Kroken, RA; Larsen, TK; Løberg, EM; Reitan, SK; Rettenbacher, M; Sinkeviciute, I; Skrede, S; Stabell, L; Steen, VM; Walla, B, 2020)
"We compared the efficacy of ziprasidone and amisulpride in the treatment of negative symptoms and overall psychopathology in subjects who had chronic schizophrenia with predominantly negative symptoms."5.12Ziprasidone and amisulpride effectively treat negative symptoms of schizophrenia: results of a 12-week, double-blind study. ( Murray, S; Olié, JP; Spina, E; Yang, R, 2006)
"To compare the efficacy and safety of amisulpride and olanzapine in subjects with schizophrenia and comorbid depression in a randomised double-blind trial."5.12A double-blind randomised comparative trial of amisulpride versus olanzapine for 2 months in the treatment of subjects with schizophrenia and comorbid depression. ( Douki, S; Vanelle, JM, 2006)
" The study evaluated the efficacy of amisulpride, fluoxetine and clomipramine at the beginning of the re-feeding phase of the treatment of restricting anorexia nervosa according to DSM-IV criteria."5.09A single blind comparison of amisulpride, fluoxetine and clomipramine in the treatment of restricting anorectics. ( Cavagnini, F; Clemente, A; Ferrari, VM; Laini, V; Lugo, F; Mantero, M; Mauri, MC; Redaelli, G; Ruggiero, GM; Zappulli, D, 2001)
"Between 40% and 70% of people with treatment-resistant schizophrenia do not respond to clozapine, despite adequate blood levels."4.95Clozapine combined with different antipsychotic drugs for treatment-resistant schizophrenia. ( Barber, S; Cipriani, A; Corsi, M; Olotu, U, 2017)
" Olanzapine produced more weight gain than all other second-generation antipsychotics except for clozapine where no difference was found."4.86Head-to-head comparisons of metabolic side effects of second generation antipsychotics in the treatment of schizophrenia: a systematic review and meta-analysis. ( Davis, JM; Hunger, H; Kissling, W; Komossa, K; Leucht, S; Lobos, CA; Rummel-Kluge, C; Schmid, F; Schwarz, S, 2010)
" This reveals that the atypical antipsychotics are most likely to induce weight gain, in particular clozapine and olanzapine."4.82[Psychotropics and weight gain]. ( Bryois, Ch; Sahli, Ch, 2004)
" Clozapine seems to have the highest risk of weight gain, followed by olanzapine and quetiapine."4.80Atypical antipsychotics and weight gain--a systematic review. ( McAskill, R; Taylor, DM, 2000)
"We compared stable patients with schizophrenia who were treated with either amisulpride or olanzapine in terms of symptomatic outcome, neurocognitive functioning, functionality, and subjective outcome."3.74Outcomes in schizophrenia outpatients treated with amisulpride or olanzapine. ( Bodner, T; Edlinger, M; Fleischhacker, WW; Hofer, A; Huber, R; Kemmler, G; Rettenbacher, MA; Sachs, G, 2007)
"Weight gain is a frequent side effect of treatment with SGAs (second-generation antipsychotics) and a leading cause for nonadherence."3.30Genetic association of the rs17782313 polymorphism with antipsychotic-induced weight gain. ( Heres, S; Leucht, S; Schreyer, KF; Steimer, W, 2023)
"Tremor and insomnia were more frequent with amisulpride, while olanzapine caused more weight gain and sedation."2.75Amisulpride versus olanzapine in the treatment of schizophrenia in Indian patients: randomized controlled trial. ( Bhowmick, S; Ghosh, M; Hazra, A, 2010)
"Six weeks of individually dosed amisulpride treatment."1.43Striatal Reward Activity and Antipsychotic-Associated Weight Change in Patients With Schizophrenia Undergoing Initial Treatment. ( Ebdrup, BH; Glenthøj, B; Nielsen, MØ; Rostrup, E; Wulff, S, 2016)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (55.00)29.6817
2010's6 (30.00)24.3611
2020's3 (15.00)2.80

Authors

AuthorsStudies
Lange, JH1
Reinders, JH1
Tolboom, JT1
Glennon, JC1
Coolen, HK1
Kruse, CG1
Schreyer, KF1
Leucht, S3
Heres, S1
Steimer, W1
Ter Hark, SE2
Jamain, S1
Schijven, D1
Lin, BD1
Bakker, MK1
Boland-Auge, A1
Deleuze, JF1
Troudet, R1
Malhotra, AK1
Gülöksüz, S2
Vinkers, CH2
Ebdrup, BH3
Kahn, RS2
Leboyer, M1
Luykx, JJ2
Johnsen, E1
Kroken, RA1
Løberg, EM1
Rettenbacher, M1
Joa, I1
Larsen, TK1
Reitan, SK1
Walla, B1
Alisauskiene, R1
Anda, LG1
Bartz-Johannessen, C1
Berle, JØ1
Bjarke, J1
Fathian, F1
Hugdahl, K1
Kjelby, E1
Sinkeviciute, I1
Skrede, S1
Stabell, L1
Steen, VM1
Fleischhacker, WW2
Barber, S1
Olotu, U1
Corsi, M1
Cipriani, A1
Pandit, R1
Cianci, D1
Winter-van Rossum, I1
Broberg, BV1
Garcia-Portilla, MP1
Bobes, J1
Huitema, ADR1
Nielsen, MØ1
Rostrup, E1
Wulff, S1
Glenthøj, B1
Bhowmick, S1
Hazra, A1
Ghosh, M1
Rummel-Kluge, C1
Komossa, K1
Schwarz, S1
Hunger, H1
Schmid, F1
Lobos, CA1
Kissling, W2
Davis, JM1
Lee, SJ1
Lee, JH1
Jung, SW1
Koo, BH1
Choi, TY1
Lee, KH1
Wagenpfeil, S1
Hamann, J1
Mortimer, AM1
Sahli, Ch1
Bryois, Ch1
Olié, JP1
Spina, E1
Murray, S1
Yang, R1
Papadimitriou, GN1
Theleritis, CG1
Dikeos, DG1
Psarros, CJ1
Soldatos, CR1
Vanelle, JM1
Douki, S1
Hofer, A1
Rettenbacher, MA1
Edlinger, M1
Huber, R1
Bodner, T1
Kemmler, G1
Sachs, G1
Linden, M1
Eich, FX1
Pyrkosch, L1
Taylor, DM1
McAskill, R1
Ruggiero, GM1
Laini, V1
Mauri, MC1
Ferrari, VM1
Clemente, A1
Lugo, F1
Mantero, M1
Redaelli, G1
Zappulli, D1
Cavagnini, F1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Bergen Psychosis Project 2 - The Bergen-Stavanger-Innsbruck-Trondheim Study[NCT01446328]Phase 4151 participants (Actual)Interventional2011-10-31Completed
Efficacy and Safety of Add-on Topiramate vs Metformin on Cardio-Metabolic Profile in Patients With Schizophrenia on Atypical Antipsychotics With Metabolic Syndrome: a Randomized Controlled Trial[NCT05663749]Phase 460 participants (Actual)Interventional2022-09-20Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for dan 2163 and Weight Gain

ArticleYear
Clozapine combined with different antipsychotic drugs for treatment-resistant schizophrenia.
    The Cochrane database of systematic reviews, 2017, 03-23, Volume: 3

    Topics: Adult; Amisulpride; Antipsychotic Agents; Aripiprazole; Clozapine; Dibenzothiazepines; Drug Resistan

2017
Head-to-head comparisons of metabolic side effects of second generation antipsychotics in the treatment of schizophrenia: a systematic review and meta-analysis.
    Schizophrenia research, 2010, Volume: 123, Issue:2-3

    Topics: Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Blood Glucose; Cholesterol; Clinic

2010
How do we choose between atypical antipsychotics? The advantages of amisulpride.
    The international journal of neuropsychopharmacology, 2004, Volume: 7 Suppl 1

    Topics: Adverse Drug Reaction Reporting Systems; Amisulpride; Antipsychotic Agents; Clinical Trials as Topic

2004
[Psychotropics and weight gain].
    Praxis, 2004, Aug-25, Volume: 93, Issue:35

    Topics: Adolescent; Adult; Amisulpride; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Aripi

2004
Atypical antipsychotics and weight gain--a systematic review.
    Acta psychiatrica Scandinavica, 2000, Volume: 101, Issue:6

    Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Dibenzothiepins;

2000

Trials

9 trials available for dan 2163 and Weight Gain

ArticleYear
Genetic association of the rs17782313 polymorphism with antipsychotic-induced weight gain.
    Psychopharmacology, 2023, Volume: 240, Issue:4

    Topics: Amisulpride; Antipsychotic Agents; Genome-Wide Association Study; Humans; Olanzapine; Polymorphism,

2023
Amisulpride, aripiprazole, and olanzapine in patients with schizophrenia-spectrum disorders (BeSt InTro): a pragmatic, rater-blind, semi-randomised trial.
    The lancet. Psychiatry, 2020, Volume: 7, Issue:11

    Topics: Adolescent; Adult; Aged; Amisulpride; Antipsychotic Agents; Aripiprazole; Female; Humans; Male; Midd

2020
Phenotypic factors associated with amisulpride-induced weight gain in first-episode psychosis patients (from the OPTiMiSE cohort).
    Acta psychiatrica Scandinavica, 2019, Volume: 140, Issue:3

    Topics: Adult; Age Factors; Amisulpride; Antipsychotic Agents; Cohort Studies; Europe; Female; Humans; Male;

2019
Amisulpride versus olanzapine in the treatment of schizophrenia in Indian patients: randomized controlled trial.
    The Australian and New Zealand journal of psychiatry, 2010, Volume: 44, Issue:3

    Topics: Adult; Amisulpride; Antipsychotic Agents; Benzodiazepines; Brief Psychiatric Rating Scale; Drug Admi

2010
A 6-week, randomized, multicentre, open-label study comparing efficacy and tolerability of amisulpride at a starting dose of 400 mg/day versus 800 mg/day in patients with acute exacerbations of schizophrenia.
    Clinical drug investigation, 2012, Volume: 32, Issue:11

    Topics: Adult; Aged; Amisulpride; Analysis of Variance; Antipsychotic Agents; Chi-Square Distribution; Disea

2012
Amisulpride is an "atypical" antipsychotic associated with low weight gain.
    Psychopharmacology, 2004, Volume: 173, Issue:1-2

    Topics: Amisulpride; Antipsychotic Agents; Databases as Topic; Dose-Response Relationship, Drug; Humans; Mal

2004
Ziprasidone and amisulpride effectively treat negative symptoms of schizophrenia: results of a 12-week, double-blind study.
    International clinical psychopharmacology, 2006, Volume: 21, Issue:3

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Amisulpride; Antipsychotic Agents; Behavioral Sympto

2006
A double-blind randomised comparative trial of amisulpride versus olanzapine for 2 months in the treatment of subjects with schizophrenia and comorbid depression.
    European psychiatry : the journal of the Association of European Psychiatrists, 2006, Volume: 21, Issue:8

    Topics: Adult; Amisulpride; Analysis of Variance; Antipsychotic Agents; Benzodiazepines; Comorbidity; Depres

2006
A single blind comparison of amisulpride, fluoxetine and clomipramine in the treatment of restricting anorectics.
    Progress in neuro-psychopharmacology & biological psychiatry, 2001, Volume: 25, Issue:5

    Topics: Adult; Amenorrhea; Amisulpride; Anorexia Nervosa; Antidepressive Agents, Second-Generation; Antidepr

2001

Other Studies

6 other studies available for dan 2163 and Weight Gain

ArticleYear
Principal component analysis differentiates the receptor binding profiles of three antipsychotic drug candidates from current antipsychotic drugs.
    Journal of medicinal chemistry, 2007, Oct-18, Volume: 50, Issue:21

    Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benzoxazines; Biogenic Monoamines; Humans; Hyperprolac

2007
A new genetic locus for antipsychotic-induced weight gain: A genome-wide study of first-episode psychosis patients using amisulpride (from the OPTiMiSE cohort).
    Journal of psychopharmacology (Oxford, England), 2020, Volume: 34, Issue:5

    Topics: Adult; Alleles; Amisulpride; Antipsychotic Agents; Cohort Studies; Female; Genetic Loci; Genome-Wide

2020
Striatal Reward Activity and Antipsychotic-Associated Weight Change in Patients With Schizophrenia Undergoing Initial Treatment.
    JAMA psychiatry, 2016, Volume: 73, Issue:2

    Topics: Adolescent; Adult; Amisulpride; Anticipation, Psychological; Antipsychotic Agents; Dopamine D2 Recep

2016
Acute weight gain induced by amisulpride monotherapy in a first-episode schizophrenic patient.
    International clinical psychopharmacology, 2006, Volume: 21, Issue:3

    Topics: Adult; Amisulpride; Antipsychotic Agents; Female; Humans; Schizophrenia; Sulpiride; Time Factors; We

2006
Outcomes in schizophrenia outpatients treated with amisulpride or olanzapine.
    Pharmacopsychiatry, 2007, Volume: 40, Issue:1

    Topics: Adult; Amisulpride; Antipsychotic Agents; Benzodiazepines; Cross-Sectional Studies; Female; Humans;

2007
Do differences in atypical antipsychotics matter in routine practice? Medication switch from olanzapine and risperidone to amisulpride.
    International clinical psychopharmacology, 2007, Volume: 22, Issue:3

    Topics: Adolescent; Adult; Amisulpride; Antipsychotic Agents; Benzodiazepines; Drug Utilization; Dyskinesia,

2007