Page last updated: 2024-10-22

dan 2163 and Hyperprolactinaemia

dan 2163 has been researched along with Hyperprolactinaemia in 30 studies

Research Excerpts

ExcerptRelevanceReference
"Risperidone and amisulpride caused hyperprolactinemia and macroprolactinemia; thus, detection of MPRL in the clinical setting should be performed as this phenomenon appears early in treatment (the second week) and continues, that can avoid unnecessary examination and treatment for asymptomatic patients with macroprolactinemia."8.12Occurrence of macroprolactinemia in schizophrenia patients treated with risperidone or amisulpride. ( Haiying, J; Haizhi, C; Jianhua, L; Jianjun, L; Jing, L; Lilei, L; Xiaocong, F; Zhenhua, W, 2022)
" We conducted this 6-month, parallel-group study to prospectively investigate the effects of the dopamine agonist cabergoline on sexual dysfunction in clinically stable patients with schizophrenia (DSM-IV, AP 194) and hyperprolactinemia (PRL > 20 ng/ml for men and PRL > 25 ng/ml for women)."7.79Effects of cabergoline on hyperprolactinemia, psychopathology, and sexual functioning in schizophrenic patients. ( Arvanitakis, P; Dimopoulou, K; Kalkavoura, CS; Lykouras, L; Michopoulos, I; Theodoropoulou, P; Tzebelikos, E, 2013)
"Relapse was determined by assessing changes in Positive and Negative Syndrome Scale (PANSS) total scores from baseline to 6 months (increased over 20% or 10% reaching 70)."5.91Relapse in patients with schizophrenia and amisulpride-induced hyperprolactinemia or olanzapine-induced metabolic disturbance after switching to other antipsychotics. ( Cai, J; Gao, M; Huang, J; Huang, Y; Kang, D; Li, L; Liu, F; Long, Y; Ou, J; Peng, X; Shao, P; Shao, T; Shen, Y; Song, C; Su, Y; Sun, M; Wang, W; Wang, X; Wu, Q; Wu, R; Xiao, J; Xie, P; Yang, Y, 2023)
" Furthermore, this case suggests that changing the regimen to aripiprazole with propranolol may be a potential option for amisulpride withdrawal akathisia superimposed on pre-existing hyperprolactinemia."4.12Amisulpride withdrawal akathisia responding to aripiprazole with propranolol in first-onset psychosis: a case report. ( Kim, SG; Seo, EH; Yang, HJ; Yoon, HJ, 2022)
"Risperidone and amisulpride caused hyperprolactinemia and macroprolactinemia; thus, detection of MPRL in the clinical setting should be performed as this phenomenon appears early in treatment (the second week) and continues, that can avoid unnecessary examination and treatment for asymptomatic patients with macroprolactinemia."4.12Occurrence of macroprolactinemia in schizophrenia patients treated with risperidone or amisulpride. ( Haiying, J; Haizhi, C; Jianhua, L; Jianjun, L; Jing, L; Lilei, L; Xiaocong, F; Zhenhua, W, 2022)
" We conducted this 6-month, parallel-group study to prospectively investigate the effects of the dopamine agonist cabergoline on sexual dysfunction in clinically stable patients with schizophrenia (DSM-IV, AP 194) and hyperprolactinemia (PRL > 20 ng/ml for men and PRL > 25 ng/ml for women)."3.79Effects of cabergoline on hyperprolactinemia, psychopathology, and sexual functioning in schizophrenic patients. ( Arvanitakis, P; Dimopoulou, K; Kalkavoura, CS; Lykouras, L; Michopoulos, I; Theodoropoulou, P; Tzebelikos, E, 2013)
"The mean dosage of amisulpride was 195."2.77Hyperprolactinemia induced by low-dosage amisulpride in Korean psychiatric patients. ( Kang, SG; Kim, TW; Lee, BH; Lee, HJ; Park, YM; Yoon, HK, 2012)
"We have investigated the categorical prevalence of hyperprolactinemia and examined the relationship between prolactin levels and subjective endocrine-related adverse effects in schizophrenia patients treated with amisulpride during a 1-year period."2.77Relationship between prolactin levels and subjective endocrine-related adverse effects in patients with schizophrenia receiving long-term treatment with amisulpride. ( Ahn, YM; Jung, DC; Kim, EY; Kim, SH; Kim, YS; Lee, NY, 2012)
"The trial was a prospective, open-label, single-center one with a flexible dosing of SGAs."2.73Differences in the effect of second-generation antipsychotics on prolactinaemia: six weeks open-label trial in female in-patients. ( Cejpková, A; Rodáková, I; Svestka, J; Synek, O; Tomanová, J, 2007)
"Relapse was determined by assessing changes in Positive and Negative Syndrome Scale (PANSS) total scores from baseline to 6 months (increased over 20% or 10% reaching 70)."1.91Relapse in patients with schizophrenia and amisulpride-induced hyperprolactinemia or olanzapine-induced metabolic disturbance after switching to other antipsychotics. ( Cai, J; Gao, M; Huang, J; Huang, Y; Kang, D; Li, L; Liu, F; Long, Y; Ou, J; Peng, X; Shao, P; Shao, T; Shen, Y; Song, C; Su, Y; Sun, M; Wang, W; Wang, X; Wu, Q; Wu, R; Xiao, J; Xie, P; Yang, Y, 2023)
"Antipsychotic drugs are the mainstay of treatment in schizophrenia."1.35Hyperprolactinemia and possibly related development of prolactinoma during amisulpride treatment; three cases. ( Akkaya, C; Ersoy, C; Kaya, B; Kirli, S; Kotan, Z; Sarandol, A, 2009)
" No significant correlation was detected between prolactin levels and either amisulpride dosage or duration of administration."1.34Amisulpride-induced hyperprolactinemia is reversible following discontinuation. ( Liappas, J; Mourikis, I; Paparrigopoulos, T; Soldatos, C; Tzavellas, E, 2007)
"Risperidone monotherapy treatment was associated with hyperprolactinaemia in 69% of patients ( n = 35) and in 100% of female patients (n = 16) and amisulpride monotherapy in 100% (n = 7)."1.34Prevalence of hyperprolactinaemia in a naturalistic cohort of schizophrenia and bipolar outpatients during treatment with typical and atypical antipsychotics. ( Bushe, C; Shaw, M, 2007)
" However, no correlation between prolactin levels and dosage could be found."1.32[Plasma prolactin level and incidence of adverse endocrinologic effects during therapy with atypical neuroleptics]. ( Fric, M; Laux, G, 2003)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's17 (56.67)29.6817
2010's9 (30.00)24.3611
2020's4 (13.33)2.80

Authors

AuthorsStudies
Lange, JH1
Reinders, JH1
Tolboom, JT1
Glennon, JC1
Coolen, HK1
Kruse, CG1
Yang, HJ1
Kim, SG1
Seo, EH1
Yoon, HJ1
Prasannakumar, A1
Suhas, S1
Kumar, V1
Cai, J1
Li, L1
Shao, T1
Sun, M1
Wang, W1
Xie, P1
Wang, X1
Yang, Y1
Long, Y1
Kang, D1
Xiao, J1
Su, Y1
Peng, X1
Huang, Y1
Gao, M1
Wu, Q1
Song, C1
Liu, F1
Shao, P1
Ou, J1
Shen, Y1
Huang, J1
Wu, R1
Zhenhua, W1
Haizhi, C1
Jing, L1
Xiaocong, F1
Jianhua, L1
Jianjun, L1
Lilei, L1
Haiying, J1
Düring, SW1
Nielsen, MØ1
Bak, N1
Glenthøj, BY1
Ebdrup, BH1
Voicu, V1
Medvedovici, A1
Ranetti, AE1
Rădulescu, FŞ1
Kalkavoura, CS1
Michopoulos, I1
Arvanitakis, P1
Theodoropoulou, P1
Dimopoulou, K1
Tzebelikos, E1
Lykouras, L1
Pasquini, M1
Berardelli, I1
Calabrò, F1
Roselli, V1
Hefner, S1
Biondi, M1
Akkaya, C1
Kaya, B1
Kotan, Z1
Sarandol, A1
Ersoy, C1
Kirli, S1
Chen, YY1
Huang, MC1
Wu, KC1
Saitis, M1
Papazisis, G1
Katsigiannopoulos, K1
Kouvelas, D1
Tschoner, A1
Engl, J1
Rettenbacher, MA1
Kaser, S1
Ott, HW1
Fleischhacker, WW1
Patsch, JR1
Ebenbichler, CF1
Höfer, P1
Friedrich, F1
Vyssoki, B1
Spindelegger, C1
Schmook, M1
Barnas, C1
Lesch, OM1
Walter, H1
Ružić, K1
Grahovac, T1
Graovac, M1
Dadić-Hero, E1
Sepić-Grahovac, D1
Sabljić, V1
Lee, BH1
Kang, SG1
Kim, TW1
Lee, HJ1
Yoon, HK1
Park, YM1
Kim, EY1
Kim, SH1
Lee, NY1
Jung, DC1
Kim, YS1
Ahn, YM1
Lee, SJ1
Lee, JH1
Jung, SW1
Koo, BH1
Choi, TY1
Lee, KH1
Marchese, G2
Ruiu, S2
Casti, P2
Saba, P2
Gessa, GL2
Pani, L2
Fric, M1
Laux, G1
Bressan, RA1
Erlandsson, K1
Spencer, EP1
Ell, PJ1
Pilowsky, LS1
Bliesener, N1
Yokusoglu, H1
Quednow, BB1
Klingmüller, D1
Kühn, KU1
Kopecek, M2
Bares, M2
Svarc, J1
Dockery, C1
Horácek, J2
Paparrigopoulos, T1
Liappas, J1
Tzavellas, E1
Mourikis, I1
Soldatos, C1
Paulzen, M1
Gründer, G1
Peritogiannis, V1
Goulia, P1
Pappas, D1
Hyphantis, T1
Mavreas, V1
Bushe, C1
Shaw, M1
Svestka, J1
Synek, O1
Tomanová, J1
Rodáková, I1
Cejpková, A1
Bartholini, F1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Therapy With Bromocriptine in Patients With Symptomatic Risperidone-Induced Hyperprolactinemia[NCT00315081]Phase 320 participants Interventional2006-05-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for dan 2163 and Hyperprolactinaemia

ArticleYear
Drug-induced hypo- and hyperprolactinemia: mechanisms, clinical and therapeutic consequences.
    Expert opinion on drug metabolism & toxicology, 2013, Volume: 9, Issue:8

    Topics: Amisulpride; Antipsychotic Agents; Aripiprazole; Blood-Brain Barrier; Humans; Hyperprolactinemia; Is

2013
Is amisulpride safe when prescribed to breast and prostate cancer patients?
    Medical hypotheses, 2013, Volume: 81, Issue:6

    Topics: Amisulpride; Antidepressive Agents; Breast Neoplasms; Depression; Female; Humans; Hyperprolactinemia

2013

Trials

6 trials available for dan 2163 and Hyperprolactinaemia

ArticleYear
Hyperprolactinemia induced by low-dosage amisulpride in Korean psychiatric patients.
    Psychiatry and clinical neurosciences, 2012, Volume: 66, Issue:1

    Topics: Adult; Amisulpride; Asian People; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Hu

2012
Relationship between prolactin levels and subjective endocrine-related adverse effects in patients with schizophrenia receiving long-term treatment with amisulpride.
    Pharmacopsychiatry, 2012, Volume: 45, Issue:2

    Topics: Adult; Amisulpride; Antipsychotic Agents; Drug Tolerance; Female; Humans; Hyperprolactinemia; Male;

2012
A 6-week, randomized, multicentre, open-label study comparing efficacy and tolerability of amisulpride at a starting dose of 400 mg/day versus 800 mg/day in patients with acute exacerbations of schizophrenia.
    Clinical drug investigation, 2012, Volume: 32, Issue:11

    Topics: Adult; Aged; Amisulpride; Analysis of Variance; Antipsychotic Agents; Chi-Square Distribution; Disea

2012
Usefulness of bromocriptine in the treatment of amisulpride-induced hyperprolactinemia: a case report.
    Pharmacopsychiatry, 2004, Volume: 37, Issue:4

    Topics: Adult; Amisulpride; Antipsychotic Agents; Bromocriptine; Estradiol; Female; Follicle Stimulating Hor

2004
Hyperprolactinemia after low dose of amisulpride.
    Neuro endocrinology letters, 2004, Volume: 25, Issue:6

    Topics: Adult; Amisulpride; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Depression; Dr

2004
Differences in the effect of second-generation antipsychotics on prolactinaemia: six weeks open-label trial in female in-patients.
    Neuro endocrinology letters, 2007, Volume: 28, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amisulpride; Antipsychotic Agents; Benzodiazepines; Dibe

2007

Other Studies

22 other studies available for dan 2163 and Hyperprolactinaemia

ArticleYear
Principal component analysis differentiates the receptor binding profiles of three antipsychotic drug candidates from current antipsychotic drugs.
    Journal of medicinal chemistry, 2007, Oct-18, Volume: 50, Issue:21

    Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benzoxazines; Biogenic Monoamines; Humans; Hyperprolac

2007
Amisulpride withdrawal akathisia responding to aripiprazole with propranolol in first-onset psychosis: a case report.
    BMC psychiatry, 2022, 01-29, Volume: 22, Issue:1

    Topics: Adult; Amisulpride; Antipsychotic Agents; Aripiprazole; Benztropine; Female; Humans; Hyperprolactine

2022
Amisulpride-Induced High Elevation in Prolactin Levels.
    The primary care companion for CNS disorders, 2023, 01-12, Volume: 25, Issue:1

    Topics: Amisulpride; Antipsychotic Agents; Humans; Hyperprolactinemia; Prolactin

2023
Relapse in patients with schizophrenia and amisulpride-induced hyperprolactinemia or olanzapine-induced metabolic disturbance after switching to other antipsychotics.
    Psychiatry research, 2023, Volume: 322

    Topics: Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Chronic Disease; Humans; Hyperprol

2023
Occurrence of macroprolactinemia in schizophrenia patients treated with risperidone or amisulpride.
    Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists, 2022, Volume: 14, Issue:1

    Topics: Amisulpride; Antipsychotic Agents; Humans; Hyperprolactinemia; Prolactin; Risperidone; Schizophrenia

2022
Sexual dysfunction and hyperprolactinemia in schizophrenia before and after six weeks of D
    Psychiatry research, 2019, Volume: 274

    Topics: Adult; Amisulpride; Antipsychotic Agents; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Fe

2019
Effects of cabergoline on hyperprolactinemia, psychopathology, and sexual functioning in schizophrenic patients.
    Experimental and clinical psychopharmacology, 2013, Volume: 21, Issue:4

    Topics: Adult; Amisulpride; Antipsychotic Agents; Cabergoline; Diagnostic and Statistical Manual of Mental D

2013
Hyperprolactinemia and possibly related development of prolactinoma during amisulpride treatment; three cases.
    Journal of psychopharmacology (Oxford, England), 2009, Volume: 23, Issue:6

    Topics: Adult; Amisulpride; Antipsychotic Agents; Brain; Female; Humans; Hyperprolactinemia; Magnetic Resona

2009
Weight gain in a patient with schizophrenia switched from quetiapine to amisulpride.
    Psychiatry and clinical neurosciences, 2008, Volume: 62, Issue:5

    Topics: Adult; Amisulpride; Antipsychotic Agents; Appetite; Dibenzothiazepines; Dose-Response Relationship,

2008
Aripiprazole resolves amisulpride and ziprasidone-induced hyperprolactinemia.
    Psychiatry and clinical neurosciences, 2008, Volume: 62, Issue:5

    Topics: Amisulpride; Antipsychotic Agents; Aripiprazole; Female; Humans; Hyperprolactinemia; Long-Term Care;

2008
Is second-generation antipsychotic-induced hyperprolactinemia due to biologically active prolactin or to biologically inactive macroprolactin? Results from a prospective study.
    The Journal of clinical psychiatry, 2009, Volume: 70, Issue:2

    Topics: Adolescent; Adult; Amisulpride; Antipsychotic Agents; Diagnosis, Differential; Female; Humans; Hyper

2009
Hyperprolactinaemia and acute psychosis: prolactinoma or medication-induced phenomenon?
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2010, Volume: 11, Issue:5

    Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Female; Follow-Up Studies; Humans; Hyperprolacti

2010
Hyperprolactinaemia with amisulpride.
    Psychiatria Danubina, 2011, Volume: 23, Issue:1

    Topics: Amisulpride; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Anxiety Disorders; Bo

2011
Effect of the amisulpride isomers on rat prolactinemia.
    European journal of pharmacology, 2002, Jul-19, Volume: 448, Issue:2-3

    Topics: Amisulpride; Animals; Dose-Response Relationship, Drug; Hyperprolactinemia; Male; Pituitary Gland; P

2002
[Plasma prolactin level and incidence of adverse endocrinologic effects during therapy with atypical neuroleptics].
    Psychiatrische Praxis, 2003, Volume: 30 Suppl 2

    Topics: Adult; Amisulpride; Antipsychotic Agents; Benzodiazepines; Depressive Disorder, Major; Dibenzothiaze

2003
Prolactinemia is uncoupled from central D2/D3 dopamine receptor occupancy in amisulpride treated patients.
    Psychopharmacology, 2004, Volume: 175, Issue:3

    Topics: Adult; Amisulpride; Antipsychotic Agents; Brain; Contrast Media; Dopamine D2 Receptor Antagonists; D

2004
Normalization of hyperprolactinaemia after withdrawal of a low dose of amisulpride.
    Neuro endocrinology letters, 2005, Volume: 26, Issue:4

    Topics: Adult; Amisulpride; Antipsychotic Agents; Depressive Disorder; Female; Humans; Hyperprolactinemia; M

2005
Amisulpride-induced hyperprolactinemia is reversible following discontinuation.
    Progress in neuro-psychopharmacology & biological psychiatry, 2007, Jan-30, Volume: 31, Issue:1

    Topics: Adult; Aged; Amisulpride; Antipsychotic Agents; Dose-Response Relationship, Drug; Female; Humans; Hy

2007
Amisulpride-induced hyperprolactinaemia is not reversed by addition of aripiprazole.
    The international journal of neuropsychopharmacology, 2007, Volume: 10, Issue:1

    Topics: Amisulpride; Antipsychotic Agents; Aripiprazole; Dopamine Agonists; Dopamine Antagonists; Drug Thera

2007
Amenorrhea after sertraline introduction in an amisulpride-treated patient with undiagnosed polycystic ovary disease.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:2

    Topics: Adult; Amenorrhea; Amisulpride; Antipsychotic Agents; Depression; Drug Interactions; Female; Humans;

2007
Prevalence of hyperprolactinaemia in a naturalistic cohort of schizophrenia and bipolar outpatients during treatment with typical and atypical antipsychotics.
    Journal of psychopharmacology (Oxford, England), 2007, Volume: 21, Issue:7

    Topics: Adult; Amisulpride; Antipsychotic Agents; Bipolar Disorder; Cohort Studies; Cross-Sectional Studies;

2007
Carmoxirole is able to reduce amisulpride-induced hyperprolactinemia without affecting its central effect.
    European journal of pharmacology, 2002, Jun-28, Volume: 447, Issue:1

    Topics: Amisulpride; Animals; Antipsychotic Agents; Binding, Competitive; Bromocriptine; Dopamine Agonists;

2002