Page last updated: 2024-10-18

dalteparin and Vascular Diseases

dalteparin has been researched along with Vascular Diseases in 9 studies

Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)

Vascular Diseases: Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.

Research Excerpts

ExcerptRelevanceReference
" We have previously reported an improved outcome of chronic diabetic foot ulcers during treatment with dalteparin."9.12Beneficial effects of dalteparin on haemostatic function and local tissue oxygenation in patients with diabetes, severe vascular disease and foot ulcers. ( Apelqvist, J; Blombäck, M; Eliasson, B; Eriksson, JW; Fagrell, B; Hamsten, A; Jörneskog, G; Kalani, M; Silveira, A; Torffvit, O, 2007)
" We have previously reported an improved outcome of chronic diabetic foot ulcers during treatment with dalteparin."5.12Beneficial effects of dalteparin on haemostatic function and local tissue oxygenation in patients with diabetes, severe vascular disease and foot ulcers. ( Apelqvist, J; Blombäck, M; Eliasson, B; Eriksson, JW; Fagrell, B; Hamsten, A; Jörneskog, G; Kalani, M; Silveira, A; Torffvit, O, 2007)
"This study was designed to assess whether use of enoxaparin during percutaneous coronary intervention (PCI) increased bleeding compared with unfractionated heparin, in addition to background therapy with eptifibatide."5.10Safety of concomitant therapy with eptifibatide and enoxaparin in patients undergoing percutaneous coronary intervention: results of the Coronary Revascularization Using Integrilin and Single bolus Enoxaparin Study. ( Bhatt, DL; Breall, JA; Casterella, PJ; Cohen, M; Corrigan, VE; Eaton, GM; Lee, BI; Lincoff, AM; Moses, JW; Pulsipher, M; Rogers, M; Ryan, TJ; Sklar, MA, 2003)
"Pain is the most prominent symptom of vasoocclusion, and hypercoagulability is a well-established pathogenic phenomenon in people with sickle cell disease."2.50Low-molecular-weight heparins for managing vasoocclusive crises in people with sickle cell disease: a summary of a cochrane systematic review. ( Fedorowicz, Z; van Zuuren, EJ, 2014)
" Moreover, subcutaneous parnaparin has a greater bioavailability and longer half-life than heparin, permitting once-daily administration for the prophylaxis of deep venous thrombosis (DVT) or the treatment of established vascular disorders."2.39Parnaparin. A review of its pharmacology, and clinical application in the prevention and treatment of thromboembolic and other vascular disorders. ( Faulds, D; Frampton, JE, 1994)
"Background: Severe progression of coronavirus disease 2019 (COVID-19) causes respiratory failure and critical illness."1.72HIGH HEPARANASE LEVEL IN SURVIVORS OF COVID-19 - INDICATOR OF VASCULAR AND PULMONARY RECOVERY? ( Adam, EH; Brkic, D; Heinicke, U; Neb, H; Ruskowski, K; Sonntagbauer, M; Talbot, SR; von Knethen, A; Zacharowski, K, 2022)
" Subtherapeutic doses of tinzaparin combined with abciximab or roxifiban resulted in a distinct synergy that improved anticoagulant and antiplatelet efficacy mediated by TF, fXa, or thrombin."1.31Comparative efficacy of different low-molecular-weight heparins (LMWHs) and drug interactions with LMWH: implications for management of vascular disorders. ( Mousa, SA, 2000)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's5 (55.56)29.6817
2010's2 (22.22)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Frampton, JE1
Faulds, D1
Neb, H1
Talbot, SR1
Ruskowski, K1
Brkic, D1
Sonntagbauer, M1
Adam, EH1
von Knethen, A1
Zacharowski, K1
Heinicke, U1
Ghaffarian, K1
Furin, M1
Bassett, R1
Bhatt, DL1
Lee, BI1
Casterella, PJ1
Pulsipher, M1
Rogers, M1
Cohen, M1
Corrigan, VE1
Ryan, TJ1
Breall, JA1
Moses, JW1
Eaton, GM1
Sklar, MA1
Lincoff, AM1
Brieger, D1
Solanki, V1
Gaynor, M1
Booth, V1
MacDonald, R1
Freedman, SB1
Kalani, M1
Silveira, A1
Blombäck, M1
Apelqvist, J1
Eliasson, B1
Eriksson, JW1
Fagrell, B1
Torffvit, O1
Hamsten, A1
Jörneskog, G1
van Zuuren, EJ1
Fedorowicz, Z1
Qari, MH1
Aljaouni, SK1
Alardawi, MS1
Fatani, H1
Alsayes, FM1
Zografos, P1
Alsaigh, M1
Alalfi, A1
Alamin, M1
Gadi, A1
Mousa, SA2

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Randomized, Double-blind, Placebo Controlled, Multi-national Study of Therapeutic Anticoagulation Strategy for Acute Chest Syndrome in Adults[NCT02580773]Phase 3200 participants (Anticipated)Interventional2016-12-16Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for dalteparin and Vascular Diseases

ArticleYear
Parnaparin. A review of its pharmacology, and clinical application in the prevention and treatment of thromboembolic and other vascular disorders.
    Drugs, 1994, Volume: 47, Issue:4

    Topics: Absorption; Animals; Biological Availability; Blood Coagulation; Half-Life; Heparin; Heparin, Low-Mo

1994
Low-molecular-weight heparins for managing vasoocclusive crises in people with sickle cell disease: a summary of a cochrane systematic review.
    Hemoglobin, 2014, Volume: 38, Issue:3

    Topics: Anemia, Sickle Cell; Female; Fibrinolytic Agents; Hemolysis; Heparin, Low-Molecular-Weight; Humans;

2014

Trials

3 trials available for dalteparin and Vascular Diseases

ArticleYear
Safety of concomitant therapy with eptifibatide and enoxaparin in patients undergoing percutaneous coronary intervention: results of the Coronary Revascularization Using Integrilin and Single bolus Enoxaparin Study.
    Journal of the American College of Cardiology, 2003, Jan-01, Volume: 41, Issue:1

    Topics: Adult; Angioplasty, Balloon, Coronary; Anticoagulants; Coronary Angiography; Drug Therapy, Combinati

2003
Beneficial effects of dalteparin on haemostatic function and local tissue oxygenation in patients with diabetes, severe vascular disease and foot ulcers.
    Thrombosis research, 2007, Volume: 120, Issue:5

    Topics: Aged; Dalteparin; Diabetes Mellitus; Double-Blind Method; Female; Fibrinolytic Agents; Foot Ulcer; H

2007
Reduction of painful vaso-occlusive crisis of sickle cell anaemia by tinzaparin in a double-blind randomized trial.
    Thrombosis and haemostasis, 2007, Volume: 98, Issue:2

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Antisickling Agents; Double-Blind Method; Female; Fibrinolyt

2007

Other Studies

4 other studies available for dalteparin and Vascular Diseases

ArticleYear
HIGH HEPARANASE LEVEL IN SURVIVORS OF COVID-19 - INDICATOR OF VASCULAR AND PULMONARY RECOVERY?
    Shock (Augusta, Ga.), 2022, 12-01, Volume: 58, Issue:6

    Topics: Cohort Studies; COVID-19; COVID-19 Drug Treatment; Endothelium, Vascular; Enoxaparin; Glucuronidase;

2022
STEMI in a young female? Consider spontaneous peripartum coronary artery dissection.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:2

    Topics: Adult; Anticoagulants; Coronary Angiography; Coronary Vessel Anomalies; Diagnosis, Differential; Eno

2017
Optimal strategy for administering enoxaparin to patients undergoing coronary angiography without angioplasty for acute coronary syndromes.
    The American journal of cardiology, 2002, May-15, Volume: 89, Issue:10

    Topics: Acute Disease; Aged; Anticoagulants; Cardiac Catheterization; Coronary Angiography; Coronary Disease

2002
Comparative efficacy of different low-molecular-weight heparins (LMWHs) and drug interactions with LMWH: implications for management of vascular disorders.
    Seminars in thrombosis and hemostasis, 2000, Volume: 26 Suppl 1

    Topics: Amidines; Antifibrinolytic Agents; Blood Coagulation; Clot Retraction; Dose-Response Relationship, D

2000