Page last updated: 2024-10-18

dalteparin and Tibial Fractures

dalteparin has been researched along with Tibial Fractures in 7 studies

Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)

Tibial Fractures: Fractures of the TIBIA.

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's4 (57.14)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tsukanov, IuT1
Noskov, VK1
Dziuba, GG1
Epanchintsev, PM1
Latacz, P1
Rostoff, P1
Wyderka, R1
Rudnik, A1
Kondys, M1
Marut, A1
Buszman, P1
Piwowarska, W1
Suto, Y1
Nagata, K1
Ahmed, SM1
Jacovides, C1
Browne, KD1
Cognetti, J1
Weber, MT1
Johnson, VE1
Leone, R1
Kaplan, LJ1
Smith, DH1
Pascual, JL1
Sems, SA1
Levy, BA1
Dajani, K1
Herrera, DA1
Templeman, DC1
McLaughlin, JA1
Paulson, MM1
Rosenthal, RE1
Selby, R1
Geerts, WH1
Kreder, HJ1
Crowther, MA1
Kaus, L1
Sealey, F1
Goel, DP1
Buckley, R1
deVries, G1
Abelseth, G1
Ni, A1
Gray, R1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Clinically-Important Venous Thromboembolism Following Lower Extremity Fractures: Epidemiology & Prevention[NCT00187408]Phase 4700 participants Interventional2002-08-31Completed
A Different Approach to Preventing Thrombosis (ADAPT): A Randomized Controlled Trial Comparing Low Molecular Weight Heparin to Acetylsalicylic Acid in Orthopedic Trauma Patients[NCT02774265]Phase 3329 participants (Actual)Interventional2016-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Deep Venous Thromboembolism

DVT and how the diagnosis was made will be recorded. The number of events in participants in each arm will be compared to evaluate efficacy. (NCT02774265)
Timeframe: 90 days

InterventionParticipants (Count of Participants)
VTE Prophylaxis With Enoxaparin 30mg BID5
VTE Prophylaxis With Aspirin 81mg BID9

Number of Participants With Pulmonary Embolism Events

Bases on imaging obtained for symptoms. (NCT02774265)
Timeframe: 90 days

InterventionParticipants (Count of Participants)
VTE Prophylaxis With Enoxaparin 30mg BID6
VTE Prophylaxis With Aspirin 81mg BID2

Number of Participants With Treatment-related Bleeding Events as Assessed by the Need for Blood Transfusions and Procedures for Bleeding Complications After Initiation of the Study Medication.

Includes a greater than 2g/dL drop in hemoglobin, blood transfusion, hematoma evacuation, re-operation for a deep surgical site infection or minor procedure for bleeding and GI bleed (NCT02774265)
Timeframe: 90 days

InterventionParticipants (Count of Participants)
VTE Prophylaxis With Enoxaparin 30mg BID52
VTE Prophylaxis With Aspirin 81mg BID53

Trials

2 trials available for dalteparin and Tibial Fractures

ArticleYear
A double-blind, randomized controlled trial of the prevention of clinically important venous thromboembolism after isolated lower leg fractures.
    Journal of orthopaedic trauma, 2015, Volume: 29, Issue:5

    Topics: Adult; Aged; Ankle Fractures; Anticoagulants; Dalteparin; Double-Blind Method; Female; Fibula; Fract

2015
A double-blind, randomized controlled trial of the prevention of clinically important venous thromboembolism after isolated lower leg fractures.
    Journal of orthopaedic trauma, 2015, Volume: 29, Issue:5

    Topics: Adult; Aged; Ankle Fractures; Anticoagulants; Dalteparin; Double-Blind Method; Female; Fibula; Fract

2015
A double-blind, randomized controlled trial of the prevention of clinically important venous thromboembolism after isolated lower leg fractures.
    Journal of orthopaedic trauma, 2015, Volume: 29, Issue:5

    Topics: Adult; Aged; Ankle Fractures; Anticoagulants; Dalteparin; Double-Blind Method; Female; Fibula; Fract

2015
A double-blind, randomized controlled trial of the prevention of clinically important venous thromboembolism after isolated lower leg fractures.
    Journal of orthopaedic trauma, 2015, Volume: 29, Issue:5

    Topics: Adult; Aged; Ankle Fractures; Anticoagulants; Dalteparin; Double-Blind Method; Female; Fibula; Fract

2015
Prophylaxis of deep-vein thrombosis in fractures below the knee: a prospective randomised controlled trial.
    The Journal of bone and joint surgery. British volume, 2009, Volume: 91, Issue:3

    Topics: Adult; Aged; Ankle Injuries; Anticoagulants; Dalteparin; Double-Blind Method; Female; Fractures, Bon

2009

Other Studies

5 other studies available for dalteparin and Tibial Fractures

ArticleYear
[Outcomes of prolonged anticoagulant prevention of thrombosis of deep veins of the crus in closed comminuted fractures of tibial bones].
    Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery, 2009, Volume: 15, Issue:1

    Topics: Anticoagulants; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Fractures, Closed; Frac

2009
[Massive pulmonary embolism mimicking ST-elevation acute coronary syndrome successfully treated with hybrid therapy in a trauma patient receiving nadroparin: diagnostic and therapeutic dilemmas].
    Kardiologia polska, 2007, Volume: 65, Issue:10

    Topics: Acute Coronary Syndrome; Angiocardiography; Angioplasty, Balloon; Diagnosis, Differential; Drug Ther

2007
A concomitant bone fracture delays cognitive recovery from traumatic brain injury.
    The journal of trauma and acute care surgery, 2018, Volume: 85, Issue:2

    Topics: Animals; Behavior, Animal; Brain; Brain Injuries, Traumatic; Cognition; Disease Models, Animal; Enox

2018
Incidence of deep venous thrombosis after temporary joint spanning external fixation for complex lower extremity injuries.
    The Journal of trauma, 2009, Volume: 66, Issue:4

    Topics: Adult; Anticoagulants; Clinical Protocols; Enoxaparin; External Fixators; Female; Fibula; Fracture F

2009
Delayed onset of anterior tibial compartment syndrome in a patient receiving low-molecular-weight heparin. A case report.
    The Journal of bone and joint surgery. American volume, 1998, Volume: 80, Issue:12

    Topics: Adult; Anterior Compartment Syndrome; Anticoagulants; Enoxaparin; Femoral Fractures; Humans; Male; P

1998