Page last updated: 2024-10-18

dalteparin and Thrombocytopenia

dalteparin has been researched along with Thrombocytopenia in 140 studies

Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)

Thrombocytopenia: A subnormal level of BLOOD PLATELETS.

Research Excerpts

ExcerptRelevanceReference
" A multicenter blinded, randomized trial compared the effectiveness of the most common pharmocoprevention strategies, unfractionated heparin (UFH) and the low-molecular-weight heparin (LMWH) dalteparin, finding no difference in the primary end point of leg deep-vein thrombosis but a reduced rate of pulmonary embolus and heparin-induced thrombocytopenia among critically ill medical-surgical patients who received dalteparin."7.80Cost-effectiveness of dalteparin vs unfractionated heparin for the prevention of venous thromboembolism in critically ill patients. ( Arabi, Y; Cade, JF; Chan, B; Cook, D; Cooper, J; Dodek, P; Doig, CJ; Ferguson, ND; Finfer, S; Fowler, RA; Geerts, W; Gould, MK; Guyatt, G; Hall, R; Heels-Ansdell, D; Jacka, MJ; Klinger, JR; Krahn, M; Marshall, JC; McIntyre, L; Mehta, S; Mittmann, N; Muscedere, J; Orford, N; Ormanidhi, O; Pinto, R; Qushmaq, I; Rocha, MG; Seppelt, I; Skrobik, YK; Sud, S; Vlahakis, N, 2014)
" dalteparin is associated with a low risk of major side effects and is as safe as the combination of abciximab and UFH."6.70Safety and efficacy of abciximab combined with dalteparin in treatment of acute coronary syndromes. ( Armstrong, P; Califf, R; Husted, S; James, S; Kontny, F; Niemminen, M; Pfisterer, M; Simoons, ML; Wallentin, L, 2002)
"Heparin-induced thrombocytopenia (HIT) is a serious adverse drug reaction due to its related risk of life- and limb-threatening thrombosis."5.72An Open-Label, Single-Arm, Pilot Intervention Study to Assess the Efficacy and Safety of Apixaban in Heparin-Induced Thrombocytopenia. ( Ansarinejad, N; Balouchzehi, S; Farasatinasab, M; Moghaddam, OM; Mohammadi, M; Nasiripour, S, 2022)
"Rivaroxaban is an oral, direct activated Factor Xa (FXa) inhibitor in advanced clinical development for the prevention and treatment of thromboembolic disorders."5.35Rivaroxaban--an oral, direct Factor Xa inhibitor--has potential for the management of patients with heparin-induced thrombocytopenia. ( Bakhos, M; Hoppensteadt, D; Iqbal, O; Jeske, WP; Maddineni, J; Messmore, HL; Prechel, M; Walenga, JM, 2008)
" Our case report suggests that antithrombotic treatment by targeting of the activated platelets with a potent platelet inhibitor during the acute phase of type II HIT syndrome followed by long-term administration of oral anticoagulation may be an additional, safe and effective therapeutic alternative that merits to be systematically studied."5.33Recurrent arterial thromboses in a woman with heparin induced thrombocytopenia, successfully managed with iloprost followed by clopidogrel. An alternative therapeutic option for heparin induced thrombocytopenia type II syndrome. ( Alexandridou, S; Betsis, D; Blouhos, K; Megalopoulos, A; Tsachalis, T; Tsalis, K; Vasiliadis, K, 2006)
"Dalteparin therapy was discontinued immediately, and anticoagulation was maintained with warfarin."5.32Cutaneous dalteparin reactions associated with antibodies of heparin-induced thrombocytopenia. ( Kovacs, MJ; Payne, SM, 2003)
"To determine whether low molecular weight heparin (LMWH) plus low-dose aspirin (LDA) is comparable in efficacy and safety to unfractionated heparin (UFH) plus LDA in the management of pregnant women with a history of recurrent spontaneous abortion secondary to antiphospholipid syndrome (APS)."5.15Enoxaparin versus unfractionated heparin in the management of recurrent abortion secondary to antiphospholipid syndrome. ( Abdou, AM; Fouda, IM; Fouda, UM; Ramadan, DI; Sayed, AM; Zaki, MM, 2011)
"An uncommon case of delayed-onset dalteparin-induced skin necrosis in an 83-year-old Caucasian female patient associated with heparin-induced thrombocytopaenia (HIT) presenting on day 30 following dalteparin therapy is reported."3.85Delayed-onset heparin-induced skin necrosis: a rare complication of perioperative heparin therapy. ( Gan, WK, 2017)
" A multicenter blinded, randomized trial compared the effectiveness of the most common pharmocoprevention strategies, unfractionated heparin (UFH) and the low-molecular-weight heparin (LMWH) dalteparin, finding no difference in the primary end point of leg deep-vein thrombosis but a reduced rate of pulmonary embolus and heparin-induced thrombocytopenia among critically ill medical-surgical patients who received dalteparin."3.80Cost-effectiveness of dalteparin vs unfractionated heparin for the prevention of venous thromboembolism in critically ill patients. ( Arabi, Y; Cade, JF; Chan, B; Cook, D; Cooper, J; Dodek, P; Doig, CJ; Ferguson, ND; Finfer, S; Fowler, RA; Geerts, W; Gould, MK; Guyatt, G; Hall, R; Heels-Ansdell, D; Jacka, MJ; Klinger, JR; Krahn, M; Marshall, JC; McIntyre, L; Mehta, S; Mittmann, N; Muscedere, J; Orford, N; Ormanidhi, O; Pinto, R; Qushmaq, I; Rocha, MG; Seppelt, I; Skrobik, YK; Sud, S; Vlahakis, N, 2014)
"Recurrent venous thromboembolism (VTE) occurs in some patients despite treatment with the standard drugs, warfarin and low-molecular-weight heparin (LMWH)."3.80Fondaparinux as alternative anticoagulant to warfarin or low-molecular-weight heparin for recurrent venous thrombosis. ( Thachil, J, 2014)
" We report a case of HIT in a postoperative orthopedic 75-year-old woman in treatment with LMWH (nadroparin) complicated by pulmonary embolism and treated successfully with recombinant hirudin."3.76Heparin-induced thrombocytopenia associated with pulmonary embolism. ( Cei, M; Mumoli, N, 2010)
" Within the treatment group, patients who received dalteparin, enoxaparin, and UFH were significantly more likely to experience coded thrombocytopenia than those in the no treatment group."3.74Cost and occurrence of thrombocytopenia in patients receiving venous thromboembolism prophylaxis following major orthopaedic surgeries. ( Farrelly, EM; Happe, LE; Sarnes, MW; Stanford, RH, 2008)
"Fixed dose 10,000 IU subcutaneous dalteparin once daily for 3 months was not associated with more complications in patients with liver or brain metastases."3.72Fixed-dose low-molecular-weight heparin for secondary prevention of venous thromboembolism in patients with disseminated cancer: a prospective cohort study. ( Jiménez, JA; Monreal, M; Roncales, J; Vilaseca, B; Zacharski, L, 2004)
"Dalteparin was associated with fewer study drug-attributable HIT-related events (P = ."2.78Heparin-induced thrombocytopenia in medical surgical critical illness. ( Bersten, AD; Cook, DJ; Crowther, MA; Crozier, TM; Davies, AR; Ernest, D; Hall, RI; Heels-Ansdell, D; Marshall, JC; McIntyre, L; Mehta, S; Poirier, G; Rocha, MG; Sheppard, JI; Vlahakis, NE; Warkentin, TE; Wood, GG, 2013)
"Internal carotid artery stenosis was asymptomatic in 55% and symptomatic in 45%."2.73Safety and efficacy of intravenous enoxaparin for carotid endarterectomy: a prospective randomized pilot trial. ( Assadian, A; Hagmüller, GW; Hübl, W; Klingler, A; Knöbl, P; Pfaffelmeyer, N; Senekowitsch, C, 2008)
"Thrombocytopenia is associated with an increased risk for adverse cardiac events and bleeding in patients presenting with acute coronary syndromes (ACS) treated with unfractionated heparin (UFH)."2.73Effect of thrombocytopenia on outcomes following treatment with either enoxaparin or unfractionated heparin in patients presenting with acute coronary syndromes. ( Antman, EM; Bradner, JE; Gibson, CM; Giugliano, RP; Jang, IK; Morrow, DA; Qin, J; Scirica, B; Shui, A; Wiviott, SD; Yeh, RW, 2007)
"Clivarin was administered subcutaneously at a fixed daily dosage of 1750 U without any adjustment or loading dosage."2.71Investigations of the immunoglobulin subtype transformation of anti-heparin-platelet factor 4 antibodies during treatment with a low-molecular-weight heparin (clivarin) in orthopedic patients. ( Ahmad, S; Bacher, HP; Fareed, J; Hoppensteadt, DA; Lassen, MR; Leitz, H; Misselwitz, F; Walenga, JM, 2003)
"Low-molecular-weight heparins are frequently used to treat venous thromboembolism, but optimal dosing regimens and clinical outcomes need further definition."2.70Effects of a low-molecular-weight heparin on thrombus regression and recurrent thromboembolism in patients with deep-vein thrombosis. ( Breddin, HK; Hach-Wunderle, V; Kakkar, VV; Nakov, R, 2001)
" dalteparin is associated with a low risk of major side effects and is as safe as the combination of abciximab and UFH."2.70Safety and efficacy of abciximab combined with dalteparin in treatment of acute coronary syndromes. ( Armstrong, P; Califf, R; Husted, S; James, S; Kontny, F; Niemminen, M; Pfisterer, M; Simoons, ML; Wallentin, L, 2002)
"Patients with unstable angina pectoris (UAP) or non-ST-segment elevation acute myocardial infarction (AMI) are at risk of death or recurrent ischemic events, despite receiving aspirin and unfractionated heparin (UFH)."2.70Prospective comparison of hemorrhagic complications after treatment with enoxaparin versus unfractionated heparin for unstable angina pectoris or non-ST-segment elevation acute myocardial infarction. ( Berkowitz, SD; Bigonzi, F; Cohen, M; Fromell, GJ; Stinnett, S, 2001)
"Deep vein thrombosis was assessed by routine bilateral contrast venography performed between postoperative day 5 and 9, or earlier if clinically suspected."2.70Subcutaneous heparin versus low-molecular-weight heparin as thromboprophylaxis in patients undergoing colorectal surgery: results of the canadian colorectal DVT prophylaxis trial: a randomized, double-blind trial. ( Anderson, DR; Atkinson, KG; Barton, P; Burnstein, M; Burul, CJ; Geerts, WH; Greenwood, C; Gregoire, RC; Marshall, JC; McLeod, RS; Ross, T; Silverman, RE; Sniderman, KW; Taylor, BM; Wilson, SR, 2001)
" Therefore, tinzaparin administered in a dosage of 75 U anti-Xa/kg BW 12 hours before surgery is significantly more protective against proximal DVT and safer than the standard regimen of 50 U anti-Xa/kg BW started 2 hours before surgery in patients undergoing primary elective hip arthroplasty."2.69Dose relation in the prevention of proximal vein thrombosis with a low molecular weight heparin (tinzaparin) in elective hip arthroplasty. ( Andersen, BS; Borris, LC; Ejstrud, P; Jensen, HP; Lassen, MR; Poulsen, KA, 2000)
" In standard clinical practice laboratory monitoring is not routinely performed, with drug dosing assessed by clinical inspection of the extracorporeal circuit, and the time for fistula needle sites to stop bleeding."2.45Review article: Low-molecular-weight heparin as an alternative anticoagulant to unfractionated heparin for routine outpatient haemodialysis treatments. ( Davenport, A, 2009)
" Due to a longer plasma half life together with high bioavailability and a linear dose-response relationship, the drugs can be safely and effectively administered in the hospital or ambulatory settings without the need to monitor the anticoagulant effect."2.42Clinical application of enoxaparin. ( Hofmann, T, 2004)
" Future issues that need to be addressed include refinement of indications for administration and patient selection, comparison between existing agents, evaluation of newer agents, and optimization of dosing to maximize benefit and safety in the use of these powerful new classes of drugs."2.41Glycoprotein IIb/IIIa antagonists and low-molecular weight heparin in acute coronary syndromes. ( Vernon, SM, 2001)
" The enhanced bioavailability of these drugs, in conjunction with their prolonged half-life, makes subcutaneous therapy, in one to two daily doses, possible."2.39Low molecular weight heparins and their use in obstetrics and gynecology. ( Fejgin, MD; Lourwood, DL, 1994)
" Studies have shown that weight-based dosing influences significantly both the time to reach a therapeutic intensity of anticoagulation and the incidence of thromboembolic recurrence."2.39Contemporary use of and future roles for heparin in antithrombotic therapy. ( Gibaldi, M; Wittkowsky, AK, 1995)
"Heparin-induced thrombocytopenia (HIT) is a serious adverse drug reaction due to its related risk of life- and limb-threatening thrombosis."1.72An Open-Label, Single-Arm, Pilot Intervention Study to Assess the Efficacy and Safety of Apixaban in Heparin-Induced Thrombocytopenia. ( Ansarinejad, N; Balouchzehi, S; Farasatinasab, M; Moghaddam, OM; Mohammadi, M; Nasiripour, S, 2022)
"Appropriate dosing of therapeutic anticoagulation during periods of thrombocytopenia remains uncertain for patients undergoing hematopoietic stem cell transplants (HSCT)."1.62Outcomes with enoxaparin dose reductions during thrombocytopenia in patients with hematopoietic stem cell transplantation (HSCT). ( Lam, J; Luk, SO; Tavares, E, 2021)
"In 2011, Memorial Sloan Kettering Cancer Center (MSKCC) implemented the following guidelines in this setting: administer full dose enoxaparin for a platelet count > 50,000/mcL, half-dose enoxaparin for a platelet count of 25,000-50,000/mcL, and hold anticoagulation for a platelet count < 25,000/mcL."1.46Enoxaparin dose reduction for thrombocytopenia in patients with cancer: a quality assessment study. ( Mantha, S; Miao, Y; Parameswaran, R; Soff, GA; Wills, J, 2017)
"We describe a patient with a giant thrombus on the apical wall of the left ventricle that occurred due to HIT syndrome after anterior myocardial infarction."1.40Giant thrombus on apical wall of left ventricle due to HIT syndrome after anterior MI. ( Balaban Kocas, B; Coskun, U; Gultekin, N; Gurmen, T; Kucukoglu, S; Sinan, UY, 2014)
"The pregnancy was carried to term and she delivered a healthy boy at 38 weeks of gestation."1.36Successful surgical management of massive pulmonary embolism during the second trimester in a parturient with heparin-induced thrombocytopenia. ( Corbi, P; Hajj-Chahine, J; Jayle, C; Tomasi, J, 2010)
"Heparin-induced thrombocytopenia is an antibody-mediated disorder exhibiting variable frequency in different clinical settings."1.36Anti-PF4/heparin antibody formation postorthopedic surgery thromboprophylaxis: the role of non-drug risk factors and evidence for a stoichiometry-based model of immunization. ( Cook, RJ; Greinacher, A; Marder, VJ; Warkentin, TE, 2010)
" While patients with renal impairment have a higher risk of bleeding and dosing of heparins is more difficult, there are no specific recommendations for bridging the latter patients."1.35Bridging of oral anticoagulation with low-molecular-weight heparin: experience in 373 patients with renal insufficiency undergoing invasive procedures. ( Hammerstingl, C; Omran, H, 2009)
"Rivaroxaban is an oral, direct activated Factor Xa (FXa) inhibitor in advanced clinical development for the prevention and treatment of thromboembolic disorders."1.35Rivaroxaban--an oral, direct Factor Xa inhibitor--has potential for the management of patients with heparin-induced thrombocytopenia. ( Bakhos, M; Hoppensteadt, D; Iqbal, O; Jeske, WP; Maddineni, J; Messmore, HL; Prechel, M; Walenga, JM, 2008)
"0% for surgical patients receiving prophylactic dosing of either dalteparin or nadroparin, and 41."1.35Compliance with platelet count monitoring recommendations and management of possible heparin-induced thrombocytopenia in hospitalized patients receiving low-molecular-weight heparin. ( Egberts, TC; Huisman, A; Schobben, AF; ten Berg, MJ; van den Bemt, PM; van Solinge, WW, 2009)
" They analyzed rates of documented symptomatic venous thromboembolism (VTE) (deep vein thrombosis and pulmonary embolism) confirmed by objective methods, major bleeding, death, thrombocytopenia, and other adverse events."1.35Evaluation of the effectiveness and safety of bemiparin in a large population of orthopedic patients in a normal clinical practice. ( Fontcuberta, J; Gómez-Outes, A; Martínez-González, J; Otero-Fernández, R; Rocha, E, 2008)
" We analysed rates of documented symptomatic venous thromboembolism (VTE) [deep-vein thrombosis (DVT) and pulmonary embolism (PE)] confirmed by objective methods, major bleeding, death, thrombocytopaenia and other adverse events up to 6 weeks."1.34A prospective observational study on the effectiveness and safety of bemiparin, first dose administered 6 h after knee or hip replacement surgery. ( Abad, JI; Gómez-Outes, A; Martínez-González, J; Rocha, E, 2007)
"Using the B16 melanoma mouse model of metastasis, subcutaneous (s."1.33Anti-metastatic effect of a non-anticoagulant low-molecular-weight heparin versus the standard low-molecular-weight heparin, enoxaparin. ( Amirkhosravi, A; Francis, JL; Linhardt, R; Mousa, SA, 2006)
"Leptospirosis is an acute generalized infectious disease, caused by spirochaetes, Leptospira interrogans."1.33Three cases of anicteric leptospirosis from Turkey: mild to severe complications. ( Demiroz, AP; Erdinc, FS; Hatipoglu, CA; Kinikli, S; Koruk, ST, 2006)
" Our case report suggests that antithrombotic treatment by targeting of the activated platelets with a potent platelet inhibitor during the acute phase of type II HIT syndrome followed by long-term administration of oral anticoagulation may be an additional, safe and effective therapeutic alternative that merits to be systematically studied."1.33Recurrent arterial thromboses in a woman with heparin induced thrombocytopenia, successfully managed with iloprost followed by clopidogrel. An alternative therapeutic option for heparin induced thrombocytopenia type II syndrome. ( Alexandridou, S; Betsis, D; Blouhos, K; Megalopoulos, A; Tsachalis, T; Tsalis, K; Vasiliadis, K, 2006)
"Dalteparin therapy was discontinued immediately, and anticoagulation was maintained with warfarin."1.32Cutaneous dalteparin reactions associated with antibodies of heparin-induced thrombocytopenia. ( Kovacs, MJ; Payne, SM, 2003)
" Today we know that the real advantage of LMWHs is due to their high bioavailability which makes safe and reliable their subcutaneous administration without laboratory monitoring."1.31[State of the art: low-molecular-weight heparin and beyond]. ( Casali, G; Cimminiello, C; Vitali, L, 2000)
"The incidence of adverse events reported could be explained by the high risk profile of the study population."1.31Venous thromboembolism during pregnancy: a retrospective study of enoxaparin safety in 624 pregnancies. ( Borel-Derlon, A; Borg, JY; Boudignat, O; Cohen, C; Conard, J; Darmon, JY; Francoual, C; Lepercq, J; Priollet, P; Schved, JF; Tournaire, M; Yvelin, N, 2001)
"We report a pregnant woman with systemic lupus erythematosus and recurrent venous thromboembolism who suffered from heparin-induced thrombocytopenia type II while treated with dalteparin sodium."1.31Management of heparin-associated thrombocytopenia in pregnancy with subcutaneous r-hirudin. ( Geberth, M; Harenberg, J; Heene, DL; Hoffmann, U; Huhle, G, 2000)
"A 43-year-old white woman with adult respiratory distress syndrome developed localized dermal necrosis and thrombocytopenia secondary to subcutaneous administration of unfractionated heparin."1.30Enoxaparin-associated dermal necrosis: a consequence of cross-reactivity with heparin-mediated antibodies. ( Kollef, MH; Schaiff, RA; Tonn, ME, 1997)
" This agent also showed sustained activity and better bioavailability characteristics than heparin."1.29Biochemical and pharmacologic profile of low molecular weight heparin (LU 47311, Clivarin). ( Ahsan, A; Fareed, J; Hoppensteadt, D; Jeske, W; Lojewski, B; Walenga, JM, 1993)

Research

Studies (140)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's25 (17.86)18.2507
2000's63 (45.00)29.6817
2010's42 (30.00)24.3611
2020's10 (7.14)2.80

Authors

AuthorsStudies
Kim, HS1
Kim, H1
Jeong, YJ1
Lee, H1
Yim, HW1
Kim, JI1
Moon, IS1
Kim, JY1
Pérez, DL1
Peña-Romero, AG1
Díaz-González, JM1
Domínguez-Cherit, J1
Righini, M1
Galanaud, JP1
Guenneguez, H1
Brisot, D1
Diard, A1
Faisse, P1
Barrellier, MT1
Hamel-Desnos, C1
Jurus, C1
Pichot, O1
Martin, M1
Mazzolai, L1
Choquenet, C1
Accassat, S1
Robert-Ebadi, H1
Carrier, M1
Le Gal, G1
Mermilllod, B1
Laroche, JP1
Bounameaux, H1
Perrier, A1
Kahn, SR1
Quere, I1
ten Berg, MJ1
van den Bemt, PM1
Huisman, A1
Schobben, AF1
Egberts, TC1
van Solinge, WW1
Mumoli, N2
Cei, M1
Betrosian, AP1
Theodossiades, G1
Lambroulis, G1
Kostantonis, D1
Balla, M1
Papanikolaou, M1
Georgiades, G1
Ng, HJ1
Lee, LH1
Stojanovich, L1
Mikovic, Z1
Mandic, V1
Popovich-Kuzmanovich, D1
Perunicic, J1
Antonijevic, NM1
Miljic, P1
Djordjevic, V1
Mikovic, D1
Kovac, M1
Djokic, M1
Mrdovic, I1
Nikolic, A1
Vasiljevic, Z1
Forette, B1
Wolmark, Y1
Barkagan, ZS1
Luzzatto, G2
Cordiano, I2
Patrassi, G2
Fabris, F2
Szücs, G1
Mikó, I1
Ajzner, E1
Póti, L1
Szepesi, K1
Furka, I1
Martineau, P1
Tawil, N1
Breuer, HW1
Müller, R1
Greinacher, A5
Cimminiello, C1
Casali, G1
Vitali, L1
Vernon, SM1
Wang, XK1
Zhang, Y1
Yang, CM1
Wang, Y1
Liu, GY1
Lozano, R1
Franco, ME1
Abad, JI1
Gómez-Outes, A2
Martínez-González, J2
Rocha, E2
Otero-Fernández, R1
Fontcuberta, J2
Pasha, AK1
McBane Ii, RD1
Byrne, EM1
Khattab, A1
Chen, F1
Bhagavatula, R1
Farasatinasab, M1
Balouchzehi, S1
Moghaddam, OM1
Ansarinejad, N1
Mohammadi, M1
Nasiripour, S1
Shen, L1
Liu, X1
Chen, L1
Gao, X1
Xu, Y1
Shi, D1
Zhao, H1
Bu, C1
Fraser, K1
Wang, H1
Dordick, JS1
Linhardt, RJ1
Zhang, F1
Shi, F1
Chi, L1
Singh, N1
Singh Lubana, S1
Tsai, HM1
Lam, J1
Tavares, E1
Luk, SO1
Demir, NA1
Basturk, A1
Ural, O1
Sumer, S1
Erdogdu, B1
Kiratli, HE1
Celik, JB1
Koplay, M1
Vatansev, H1
Sadeghipour, P2
Talasaz, AH2
Rashidi, F1
Sharif-Kashani, B1
Beigmohammadi, MT1
Farrokhpour, M1
Sezavar, SH1
Payandemehr, P1
Dabbagh, A1
Moghadam, KG1
Jamalkhani, S1
Khalili, H2
Yadollahzadeh, M1
Riahi, T1
Rezaeifar, P1
Tahamtan, O1
Matin, S1
Abedini, A1
Lookzadeh, S1
Rahmani, H1
Zoghi, E1
Mohammadi, K1
Abri, H1
Tabrizi, S1
Mousavian, SM1
Shahmirzaei, S1
Bakhshandeh, H1
Amin, A1
Rafiee, F1
Baghizadeh, E1
Mohebbi, B1
Parhizgar, SE1
Aliannejad, R1
Eslami, V1
Kashefizadeh, A1
Kakavand, H1
Hosseini, SH1
Shafaghi, S1
Ghazi, SF1
Najafi, A1
Jimenez, D1
Gupta, A1
Madhavan, MV1
Sethi, SS1
Parikh, SA1
Monreal, M2
Hadavand, N1
Hajighasemi, A1
Maleki, M1
Sadeghian, S1
Piazza, G1
Kirtane, AJ1
Van Tassell, BW1
Dobesh, PP1
Stone, GW1
Lip, GYH1
Krumholz, HM1
Goldhaber, SZ2
Bikdeli, B1
Haughton, B1
Haughton, J1
George Norman, J1
Navid, A1
Allport, K1
Andrews, M1
Mannan, K1
Livesey, J1
Voudris, V1
Georgiadou, P1
Kalogris, P1
Kostelidou, T1
Karabinis, A1
Gerotziafas, G1
Brouwers, JRBJ1
Roeters van Lennep, JE1
Beinema, MJ1
Sinan, UY1
Coskun, U1
Balaban Kocas, B1
Gultekin, N1
Gurmen, T1
Kucukoglu, S1
Loidi Pascual, L1
Valcayo Peñalba, A1
Yerani Ruiz de Azúa Ciria, A1
Yanguas Bayona, I1
Grampp, G1
Bonafede, M1
Felix, T1
Li, E1
Malecki, M1
Sprafka, JM1
Dang, JD1
Davis, LE1
Giuliani, E1
Melegari, G1
Farinetti, A1
Barbieri, A1
Mattioli, AV1
Campbell, PM1
Ippoliti, C1
Parmar, S1
Mantha, S1
Miao, Y1
Wills, J1
Parameswaran, R1
Soff, GA1
Walenga, JM4
Prechel, M1
Jeske, WP2
Hoppensteadt, D2
Maddineni, J1
Iqbal, O1
Messmore, HL2
Bakhos, M1
Kim, GH1
Hahn, DK1
Kellner, CP1
Komotar, RJ1
Starke, R1
Garrett, MC1
Yao, J1
Cleveland, J1
Mayer, SA1
Connolly, ES1
Hacobian, M1
Shetty, R1
Niles, CM1
Gerhard-Herman, M1
Vallurupalli, N1
Baroletti, S1
McKean, SC1
Sonis, J1
Parasuraman, S1
Kosowsky, JM1
Hammerstingl, C3
Omran, H3
Davenport, A1
Petit, JS1
Murat, O1
Perrier, S1
Lepouse, C1
Jaussaud, M1
Léon, A1
Famularo, G1
Gasbarrone, L1
Minisola, G1
De Simone, C1
Iturbe, T1
Español, I1
Sánchez, A1
Rivera, J1
Warkentin, TE5
Cook, RJ2
Marder, VJ2
Hajj-Chahine, J1
Jayle, C1
Tomasi, J1
Corbi, P1
Illes, M1
Klaus, S1
Simon, JC1
Treudler, R1
Sachithanandan, A1
Fouda, UM1
Sayed, AM1
Abdou, AM1
Ramadan, DI1
Fouda, IM1
Zaki, MM1
Dashti-Khavidaki, S1
Najmedin, F1
Hosseinpoor, R1
Rosenberger, LH1
Smith, PW1
Sawyer, RG1
Olah, Z2
Bereczky, Z1
Szarvas, M1
Boda, Z2
Montero Ruiz, E1
Baldominos Utrilla, G1
López Álvarez, J1
Santolaya Perrin, R1
Leroux, D1
Canépa, S1
Viskov, C1
Mourier, P1
Herman, F1
Rollin, J1
Gruel, Y1
Pouplard, C1
Kerenyi, A1
Kappelmayer, J1
Schlammadinger, A1
Razso, K1
Cakmak, HA1
Değirmenci, E1
Ikizceli, I1
Ibrahim, RB2
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Hirsh, J2
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Fejgin, MD1
Lourwood, DL1
Colwell, CW1
Spiro, TE2
Trowbridge, AA3
Morris, BA1
Kwaan, HC1
Blaha, JD1
Comerota, AJ1
Skoutakis, VA1
Grozovski, ES1
Cohen, JD1
Grunberg, G1
Keslin, J1
Gassner, S1
Macklon, NS1
Greer, IA1
Reid, AW1
Walker, ID1
Gibaldi, M1
Wittkowsky, AK1
Slocum, MM1
Adams, JG1
Teel, R1
Spadone, DP1
Silver, D2
Ganjoo, AK1
Harloff, MG1
Johnson, WD1
Watters, M1
Tonn, ME1
Schaiff, RA1
Kollef, MH1
James, JK1
Peters, FP1
Barratt, SM1
Ruff, SJ1
Edwards, RC1
Merli, G1
Olsson, CG1
Abildgaard, U1
Davidson, BL1
Elias, D1
Grigg, A1
Musset, D1
Rodgers, GM1
Yusen, RD1
Zawilska, K1
McLeod, RS1
Geerts, WH1
Sniderman, KW1
Greenwood, C1
Gregoire, RC1
Taylor, BM1
Silverman, RE1
Atkinson, KG1
Burnstein, M1
Marshall, JC3
Burul, CJ1
Anderson, DR1
Ross, T1
Wilson, SR1
Barton, P1
Berkowitz, SD1
Stinnett, S1
Cohen, M1
Fromell, GJ1
Bigonzi, F1
Lepercq, J1
Conard, J1
Borel-Derlon, A1
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Boudignat, O1
Francoual, C1
Priollet, P1
Cohen, C1
Yvelin, N1
Schved, JF1
Tournaire, M1
Borg, JY1
Kormanová, K1
Krska, Z1
Trca, S1
Pesková, M1
Korínková, P1
Lindhoff-Last, E1
Nakov, R2
Misselwitz, F3
Breddin, HK3
Bauersachs, R1
Ahmad, S2
Haas, S2
Hoppensteadt, DA2
Lietz, H1
Reid, U1
Bender, N1
Bacher, P1
Gaikwad, BS1
Fareed, J3
Bacher, HP1
Lassen, MR2
Leitz, H1
Jeske, W1
Lojewski, B1
Ahsan, A1
Hach-Wunderle, V1
Kakkar, VV1
Riess, H1
Koppenhagen, K1
Tolle, A1
Kemkes-Matthes, B1
Gräve, M1
Patek, F1
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Gan, WK1
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Hassell, KL1
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Geerts, W2
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Guyatt, G2
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Clinical Trials (12)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Contention Alone Versus Anticoagulation for Symptomatic Calf Vein Thrombosis Diagnosed by Ultrasonography[NCT00421538]Phase 3260 participants (Actual)Interventional2008-01-31Completed
The API-CALF Study: Apixaban to Treat Calf Vein Thrombosis[NCT04981327]Phase 31,300 participants (Anticipated)Interventional2022-09-01Not yet recruiting
Intermediate-dose Versus Standard Prophylactic Anticoagulation In cRitically-ill pATIents With COVID-19: An opeN Label Randomized Controlled Trial---A Randomized Trial of Atorvastatin vs. Placebo In Critically-ill Patients With COVID-19[NCT04486508]Phase 3600 participants (Actual)Interventional2020-07-30Completed
Evaluation of the Effect of Exogenous Surfactant Through Nebulizer Mask on Clinical Outcomes in Covid-19 Patients[NCT04847375]60 participants (Anticipated)Interventional2021-04-20Not yet recruiting
Low-molecular-weight Heparin Versus Unfractionated Heparin in Pregnant Women With History of Recurrent Abortion Secondary to Antiphospholipid Syndrome. A Randomized Controlled Trial[NCT01051778]Phase 260 participants (Actual)Interventional2006-06-30Completed
A Hemodynamic Comparison of Stationary and Portable Pneumatic Compression Devices[NCT02345642]20 participants (Actual)Interventional2015-02-28Completed
Once Daily Enoxaparin for Outpatient Treatment of Acute Deep Venous Thrombosis and/or Pulmonary Embolism[NCT00413374]40 participants (Actual)Interventional2006-05-31Completed
Low-molecular-weight Heparin to Prevent Recurrent VTE in Pregnancy: a Randomized Controlled Trial of Two Doses[NCT01828697]Phase 41,110 participants (Actual)Interventional2013-04-24Completed
An Efficacy and Safety Study of New Oral Anticoagulants and Vitamin K Antagonists for the Anticoagulation for the Implantation of Vena Cava Filters: A Prospective Randomized Controlled Trial[NCT04066764]Phase 3200 participants (Anticipated)Interventional2020-05-08Recruiting
PROphylaxis for ThromboEmbolism in Critical Care Trial (PROTECT)[NCT00182143]Phase 33,659 participants (Actual)Interventional2006-05-31Completed
Study of the Bioaccumulation of Tinzaparin in Renally Impaired Patients When Given at Prophylactic Doses[NCT02719418]28 participants (Actual)Observational2016-02-01Completed
Incidence and Characteristics of Pulmonary Embolism in COVID-19 Patients Hospitalized for Acute Respiratory Syndrome[NCT04420312]1,024 participants (Actual)Observational2020-03-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Live Birth Rate = (Number of Live Births / Total Number of Pregnancies)

Live birth occurs when a fetus (> 24 weeks ) , exits the maternal body and subsequently shows signs of life, such as voluntary movement, heartbeat, or pulsation of the umbilical cord. (NCT01051778)
Timeframe: pregnancy > 24weeks gestation

InterventionPercentage of pregnancies (Number)
Enoxaparin 40 mg /Day Plus Low Dose Aspirin24
Heparin Calcium 5,000 U Twice Daily Plus Low Dose Aspirin20

Peak Venous Velocity

Ultrasound of the venous system just below the saphenofemoral junction to assess the venous velocity will be taken before and after application the VenaFlow and the ActiveCare+S.F.T pneumatic compression devices. Change from Baseline in Peak Venous Velocity 30 minutes after Device is applied is recorded. (NCT02345642)
Timeframe: Change from Baseline in Peak Venous Velocity 30 minutes after Device is Applied

,
Interventioncm/s (Mean)
Delta PVV from before to after Venaflow (Standing)Delta PVV from before to after Venaflow (Supine)delta PVV from before to after Activeca (Standing)delta PVV from before to after Activecare (supine)
10 Healthy Patients Without THA127.987.132.640.5
10 Patients With THA on Post-Op Day 2155.786.841.937.8

Death

All-cause mortality (NCT00413374)
Timeframe: 30 Days

InterventionParticipants (Count of Participants)
Enoxaparin 1.5 mg/kg Once Daily0
Enoxaparin 1 mg/kg Twice Daily0

Major Bleeding Complication

Major bleeding complication as defined as spinal, retroperitoneal, or intracranial bleeding; drop in hemoglobin ≥2g/dl or transfusion ≥2U or surgical or medical intervention, death related to bleeding. (NCT00413374)
Timeframe: 30 Days

Interventionparticipants (Number)
Enoxaparin 1.5 mg/kg Daily0
Enoxaparin 1 mg/kg Twice Daily3

Recurrent VTE

Major clotting complication (recurrent VTE) as defined as recurrent acute pulmonary embolism confirmed on chest CT or recurrent deep vein thrombosis in the contralateral extremity confirmed with venous ultrasound or CT scan while on once daily enoxaparin therapy. (NCT00413374)
Timeframe: 30 Days

Interventionparticipants (Number)
Enoxaparin 1.5 mg/kg Daily1
Enoxaparin 1 mg/kg Twice Daily3

Reviews

11 reviews available for dalteparin and Thrombocytopenia

ArticleYear
Low-molecular-weight heparins in the treatment of deep-vein thrombosis.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:5

    Topics: Blood Platelets; Capillary Permeability; Dalteparin; Enoxaparin; Fibrinolytic Agents; Hemorrhage; He

1998
Glycoprotein IIb/IIIa antagonists and low-molecular weight heparin in acute coronary syndromes.
    Cardiology clinics, 2001, Volume: 19, Issue:2

    Topics: Abciximab; Angina, Unstable; Antibodies, Monoclonal; Coronary Artery Bypass; Dalteparin; Enoxaparin;

2001
Biosimilars of low molecular weight heparins: Relevant background information for your drug formulary.
    British journal of clinical pharmacology, 2019, Volume: 85, Issue:11

    Topics: Anticoagulants; Biosimilar Pharmaceuticals; Drug Approval; Enoxaparin; Europe; Humans; Practice Guid

2019
Review article: Low-molecular-weight heparin as an alternative anticoagulant to unfractionated heparin for routine outpatient haemodialysis treatments.
    Nephrology (Carlton, Vic.), 2009, Volume: 14, Issue:5

    Topics: Anticoagulants; Drug Costs; Enoxaparin; Hemodiafiltration; Heparin, Low-Molecular-Weight; Humans; Re

2009
Clinical application of enoxaparin.
    Expert review of cardiovascular therapy, 2004, Volume: 2, Issue:3

    Topics: Anticoagulants; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Enoxaparin; Fibrinolytic Ag

2004
Enoxaparin can be used safely in patients with severe thrombocytopenia due to intensive chemotherapy regimens.
    Leukemia & lymphoma, 2004, Volume: 45, Issue:7

    Topics: Adult; Aged; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Catheterization, Centra

2004
[Thrombosis prophylaxis with heparins in intensive care patients].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2005, Volume: 40, Issue:3

    Topics: Age Factors; Anticoagulants; APACHE; Critical Care; Enoxaparin; Heparin; Heparin Antagonists; Hepari

2005
Gestational thrombocythaemia associated with intrauterine death: case report and a review of the literature.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2006, Volume: 26, Issue:1

    Topics: Anticoagulants; Enoxaparin; Female; Fetal Death; Humans; Placenta; Placenta Diseases; Pregnancy; Pre

2006
Low molecular weight heparins and their use in obstetrics and gynecology.
    Obstetrical & gynecological survey, 1994, Volume: 49, Issue:6

    Topics: Clinical Trials as Topic; Enoxaparin; Female; Fetus; Gynecology; Hemorrhage; Heparin, Low-Molecular-

1994
Contemporary use of and future roles for heparin in antithrombotic therapy.
    Journal of clinical pharmacology, 1995, Volume: 35, Issue:11

    Topics: Anticoagulants; Antithrombins; Enoxaparin; Heparin; Heparin, Low-Molecular-Weight; Hirudins; Humans;

1995
Reviparin sodium - a new low molecular weight heparin.
    Expert opinion on pharmacotherapy, 2002, Volume: 3, Issue:2

    Topics: Absorption; Anticoagulants; Child; Drug Evaluation; Factor Xa Inhibitors; Female; Heparin, Low-Molec

2002

Trials

23 trials available for dalteparin and Thrombocytopenia

ArticleYear
Anticoagulant therapy for symptomatic calf deep vein thrombosis (CACTUS): a randomised, double-blind, placebo-controlled trial.
    The Lancet. Haematology, 2016, Volume: 3, Issue:12

    Topics: Adult; Aged; Anticoagulants; Canada; Double-Blind Method; Early Termination of Clinical Trials; Exan

2016
Anticoagulant therapy for symptomatic calf deep vein thrombosis (CACTUS): a randomised, double-blind, placebo-controlled trial.
    The Lancet. Haematology, 2016, Volume: 3, Issue:12

    Topics: Adult; Aged; Anticoagulants; Canada; Double-Blind Method; Early Termination of Clinical Trials; Exan

2016
Anticoagulant therapy for symptomatic calf deep vein thrombosis (CACTUS): a randomised, double-blind, placebo-controlled trial.
    The Lancet. Haematology, 2016, Volume: 3, Issue:12

    Topics: Adult; Aged; Anticoagulants; Canada; Double-Blind Method; Early Termination of Clinical Trials; Exan

2016
Anticoagulant therapy for symptomatic calf deep vein thrombosis (CACTUS): a randomised, double-blind, placebo-controlled trial.
    The Lancet. Haematology, 2016, Volume: 3, Issue:12

    Topics: Adult; Aged; Anticoagulants; Canada; Double-Blind Method; Early Termination of Clinical Trials; Exan

2016
[Calcium nadroparin in the prevention of thromboembolic disease in elderly subjects. Study of tolerance].
    Presse medicale (Paris, France : 1983), 1995, Mar-25, Volume: 24, Issue:12

    Topics: Aged; Aged, 80 and over; Female; Hemorrhage; Heparin; Humans; Injections, Subcutaneous; Male; Nadrop

1995
Use of unfractionated heparin and a low-molecular-weight heparin following thrombolytic therapy for acute ST-segment elevation myocardial infarction.
    Clinical drug investigation, 2006, Volume: 26, Issue:6

    Topics: Aged; Aspirin; Blood Coagulation; Drug Administration Schedule; Drug Therapy, Combination; Electroca

2006
Effect of Intermediate-Dose vs Standard-Dose Prophylactic Anticoagulation on Thrombotic Events, Extracorporeal Membrane Oxygenation Treatment, or Mortality Among Patients With COVID-19 Admitted to the Intensive Care Unit: The INSPIRATION Randomized Clinic
    JAMA, 2021, 04-27, Volume: 325, Issue:16

    Topics: Aged; Anticoagulants; COVID-19; Drug Administration Schedule; Enoxaparin; Extracorporeal Membrane Ox

2021
Effect of Intermediate-Dose vs Standard-Dose Prophylactic Anticoagulation on Thrombotic Events, Extracorporeal Membrane Oxygenation Treatment, or Mortality Among Patients With COVID-19 Admitted to the Intensive Care Unit: The INSPIRATION Randomized Clinic
    JAMA, 2021, 04-27, Volume: 325, Issue:16

    Topics: Aged; Anticoagulants; COVID-19; Drug Administration Schedule; Enoxaparin; Extracorporeal Membrane Ox

2021
Effect of Intermediate-Dose vs Standard-Dose Prophylactic Anticoagulation on Thrombotic Events, Extracorporeal Membrane Oxygenation Treatment, or Mortality Among Patients With COVID-19 Admitted to the Intensive Care Unit: The INSPIRATION Randomized Clinic
    JAMA, 2021, 04-27, Volume: 325, Issue:16

    Topics: Aged; Anticoagulants; COVID-19; Drug Administration Schedule; Enoxaparin; Extracorporeal Membrane Ox

2021
Effect of Intermediate-Dose vs Standard-Dose Prophylactic Anticoagulation on Thrombotic Events, Extracorporeal Membrane Oxygenation Treatment, or Mortality Among Patients With COVID-19 Admitted to the Intensive Care Unit: The INSPIRATION Randomized Clinic
    JAMA, 2021, 04-27, Volume: 325, Issue:16

    Topics: Aged; Anticoagulants; COVID-19; Drug Administration Schedule; Enoxaparin; Extracorporeal Membrane Ox

2021
Enoxaparin versus unfractionated heparin in the management of recurrent abortion secondary to antiphospholipid syndrome.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2011, Volume: 112, Issue:3

    Topics: Abortion, Habitual; Adult; Antibodies, Antiphospholipid; Anticoagulants; Antiphospholipid Syndrome;

2011
Anti-platelet factor 4/heparin antibodies in orthopedic surgery patients receiving antithrombotic prophylaxis with fondaparinux or enoxaparin.
    Blood, 2005, Dec-01, Volume: 106, Issue:12

    Topics: Anticoagulants; Cross Reactions; Double-Blind Method; Enoxaparin; Fondaparinux; Hip; Humans; Immunoe

2005
Effect of thrombocytopenia on outcomes following treatment with either enoxaparin or unfractionated heparin in patients presenting with acute coronary syndromes.
    The American journal of cardiology, 2007, Dec-15, Volume: 100, Issue:12

    Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Comorbidity; Enoxaparin; Female; Heparin; Humans; Inc

2007
Safety and efficacy of intravenous enoxaparin for carotid endarterectomy: a prospective randomized pilot trial.
    Journal of vascular surgery, 2008, Volume: 47, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Blood Loss, Surgical; Blood Transfusion; Brain Ische

2008
Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin.
    The New England journal of medicine, 1995, May-18, Volume: 332, Issue:20

    Topics: Confidence Intervals; Double-Blind Method; Enoxaparin; Female; Heparin; Humans; Immunoglobulin G; Od

1995
Use of enoxaparin, a low-molecular-weight heparin, and unfractionated heparin for the prevention of deep venous thrombosis after elective hip replacement. A clinical trial comparing efficacy and safety. Enoxaparin Clinical Trial Group.
    The Journal of bone and joint surgery. American volume, 1994, Volume: 76, Issue:1

    Topics: Aged; Alanine Transaminase; Drug Administration Schedule; Enoxaparin; Female; Hemoglobins; Hemorrhag

1994
Subcutaneous enoxaparin once or twice daily compared with intravenous unfractionated heparin for treatment of venous thromboembolic disease.
    Annals of internal medicine, 2001, Feb-06, Volume: 134, Issue:3

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Drug Administ

2001
Subcutaneous heparin versus low-molecular-weight heparin as thromboprophylaxis in patients undergoing colorectal surgery: results of the canadian colorectal DVT prophylaxis trial: a randomized, double-blind trial.
    Annals of surgery, 2001, Volume: 233, Issue:3

    Topics: Anticoagulants; Blood Loss, Surgical; Canada; Colectomy; Double-Blind Method; Enoxaparin; Female; He

2001
Prospective comparison of hemorrhagic complications after treatment with enoxaparin versus unfractionated heparin for unstable angina pectoris or non-ST-segment elevation acute myocardial infarction.
    The American journal of cardiology, 2001, Dec-01, Volume: 88, Issue:11

    Topics: Aged; Angina, Unstable; Antifibrinolytic Agents; Double-Blind Method; Electrocardiography; Enoxapari

2001
Incidence and clinical relevance of heparin-induced antibodies in patients with deep vein thrombosis treated with unfractionated or low-molecular-weight heparin.
    British journal of haematology, 2002, Volume: 118, Issue:4

    Topics: Anticoagulants; Autoantibodies; Drug Administration Schedule; Female; Heparin; Heparin, Low-Molecula

2002
Differential effects of clivarin and heparin in patients undergoing hip and knee surgery for the generation of anti-heparin-platelet factor 4 antibodies.
    Thrombosis research, 2002, Oct-01, Volume: 108, Issue:1

    Topics: Adult; Aged; Anticoagulants; Autoantibodies; Double-Blind Method; Female; Heparin; Heparin, Low-Mole

2002
Investigations of the immunoglobulin subtype transformation of anti-heparin-platelet factor 4 antibodies during treatment with a low-molecular-weight heparin (clivarin) in orthopedic patients.
    Archives of pathology & laboratory medicine, 2003, Volume: 127, Issue:5

    Topics: Adolescent; Antibodies, Anti-Idiotypic; Antibody Specificity; Enzyme-Linked Immunosorbent Assay; Fib

2003
Effects of a low-molecular-weight heparin on thrombus regression and recurrent thromboembolism in patients with deep-vein thrombosis.
    The New England journal of medicine, 2001, Mar-01, Volume: 344, Issue:9

    Topics: Acute Disease; Anticoagulants; Drug Administration Schedule; Female; Hemorrhage; Heparin; Heparin, L

2001
Fixed-dose, body weight-independent subcutaneous low molecular weight heparin Certoparin compared with adjusted-dose intravenous unfractionated heparin in patients with proximal deep venous thrombosis.
    Thrombosis and haemostasis, 2003, Volume: 90, Issue:2

    Topics: Aged; Body Weight; Dose-Response Relationship, Drug; Female; Hemorrhage; Heparin; Heparin, Low-Molec

2003
Heparin-induced thrombocytopenia in medical surgical critical illness.
    Chest, 2013, Volume: 144, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Blood Platelets; Critical Illness; Dalteparin; Dose-

2013
Dalteparin versus unfractionated heparin in critically ill patients.
    The New England journal of medicine, 2011, Apr-07, Volume: 364, Issue:14

    Topics: Anticoagulants; Critical Illness; Dalteparin; Female; Hemorrhage; Heparin; Humans; Incidence; Inject

2011
Dalteparin versus unfractionated heparin in critically ill patients.
    The New England journal of medicine, 2011, Apr-07, Volume: 364, Issue:14

    Topics: Anticoagulants; Critical Illness; Dalteparin; Female; Hemorrhage; Heparin; Humans; Incidence; Inject

2011
Dalteparin versus unfractionated heparin in critically ill patients.
    The New England journal of medicine, 2011, Apr-07, Volume: 364, Issue:14

    Topics: Anticoagulants; Critical Illness; Dalteparin; Female; Hemorrhage; Heparin; Humans; Incidence; Inject

2011
Dalteparin versus unfractionated heparin in critically ill patients.
    The New England journal of medicine, 2011, Apr-07, Volume: 364, Issue:14

    Topics: Anticoagulants; Critical Illness; Dalteparin; Female; Hemorrhage; Heparin; Humans; Incidence; Inject

2011
Dalteparin versus unfractionated heparin in critically ill patients.
    The New England journal of medicine, 2011, Apr-07, Volume: 364, Issue:14

    Topics: Anticoagulants; Critical Illness; Dalteparin; Female; Hemorrhage; Heparin; Humans; Incidence; Inject

2011
Dalteparin versus unfractionated heparin in critically ill patients.
    The New England journal of medicine, 2011, Apr-07, Volume: 364, Issue:14

    Topics: Anticoagulants; Critical Illness; Dalteparin; Female; Hemorrhage; Heparin; Humans; Incidence; Inject

2011
Dalteparin versus unfractionated heparin in critically ill patients.
    The New England journal of medicine, 2011, Apr-07, Volume: 364, Issue:14

    Topics: Anticoagulants; Critical Illness; Dalteparin; Female; Hemorrhage; Heparin; Humans; Incidence; Inject

2011
Dalteparin versus unfractionated heparin in critically ill patients.
    The New England journal of medicine, 2011, Apr-07, Volume: 364, Issue:14

    Topics: Anticoagulants; Critical Illness; Dalteparin; Female; Hemorrhage; Heparin; Humans; Incidence; Inject

2011
Dalteparin versus unfractionated heparin in critically ill patients.
    The New England journal of medicine, 2011, Apr-07, Volume: 364, Issue:14

    Topics: Anticoagulants; Critical Illness; Dalteparin; Female; Hemorrhage; Heparin; Humans; Incidence; Inject

2011
Safety and efficacy of abciximab combined with dalteparin in treatment of acute coronary syndromes.
    European heart journal, 2002, Volume: 23, Issue:19

    Topics: Abciximab; Acute Disease; Aged; Antibodies, Monoclonal; Anticoagulants; Cohort Studies; Coronary Dis

2002
Dose relation in the prevention of proximal vein thrombosis with a low molecular weight heparin (tinzaparin) in elective hip arthroplasty.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2000, Volume: 6, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Blood Transfusion; Double-Blind Meth

2000
Ardeparin sodium for extended out-of-hospital prophylaxis against venous thromboembolism after total hip or knee replacement. A randomized, double-blind, placebo-controlled trial.
    Annals of internal medicine, 2000, Jun-06, Volume: 132, Issue:11

    Topics: Adult; Aged; Ambulatory Care; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Cause

2000

Other Studies

106 other studies available for dalteparin and Thrombocytopenia

ArticleYear
Comparative Analysis of the Suspected Heparin-Induced Thrombocytopenia Level in Korea.
    Basic & clinical pharmacology & toxicology, 2017, Volume: 121, Issue:4

    Topics: Aged; Anticoagulants; Dalteparin; Drug Compounding; Drug Monitoring; Enoxaparin; Female; Humans; Inc

2017
Nadroparin-induced skin necrosis: clinical manifestation of HIT-2 even in the absence of thrombocytopaenia.
    BMJ case reports, 2016, Apr-26, Volume: 2016

    Topics: Adult; Humans; Male; Nadroparin; Necrosis; Skin Diseases; Thrombocytopenia

2016
Compliance with platelet count monitoring recommendations and management of possible heparin-induced thrombocytopenia in hospitalized patients receiving low-molecular-weight heparin.
    The Annals of pharmacotherapy, 2009, Volume: 43, Issue:9

    Topics: Adult; Aged; Anticoagulants; Cohort Studies; Dalteparin; Databases, Factual; Drug Monitoring; Female

2009
Heparin-induced thrombocytopenia associated with pulmonary embolism.
    Clinical cardiology, 2010, Volume: 33, Issue:2

    Topics: Aged; Antibodies; Female; Fibrinolytic Agents; Fractures, Bone; Hirudins; Humans; Nadroparin; Orthop

2010
Heparin-induced thrombocytopenia with pulmonary embolism and disseminated intravascular coagulation associated with low-molecular-weight heparin.
    The American journal of the medical sciences, 2003, Volume: 325, Issue:1

    Topics: Arthroplasty, Replacement, Hip; Disseminated Intravascular Coagulation; Female; Humans; Immunoglobul

2003
Heparin-induced thrombocytopenia: acknowledging its presence in low-molecular weight heparin therapy.
    International journal of hematology, 2003, Volume: 77, Issue:2

    Topics: Aged; Anticoagulants; Female; Heparin, Low-Molecular-Weight; Humans; Nadroparin; Thrombocytopenia; T

2003
Treatment of antiphospholipid syndrome in pregnancy with low doses of intravenous immunoglobulin.
    The Israel Medical Association journal : IMAJ, 2007, Volume: 9, Issue:7

    Topics: Adult; Anti-Inflammatory Agents; Antiphospholipid Syndrome; Autoantibodies; Dexamethasone; Dose-Resp

2007
Clinical challenge: heparin-induced thrombocytopenia type II (HIT II) or pseudo-HIT in a patient with antiphospholipid syndrome.
    Journal of thrombosis and thrombolysis, 2008, Volume: 26, Issue:2

    Topics: Administration, Oral; Adult; Antibodies; Anticoagulants; Antiphospholipid Syndrome; Diagnosis, Diffe

2008
[The use of fraxiparin for the prevention and treatment of thromboembolism in patients with heparin-induced thrombocytopenia].
    Terapevticheskii arkhiv, 1993, Volume: 65, Issue:10

    Topics: Adult; Disseminated Intravascular Coagulation; Drug Evaluation; Female; Heparin; Humans; Male; Middl

1993
Heparin-induced thrombocytopenia: discrepancy between the presence of IgG cross-reacting in vitro with fraxiparine and its successful clinical use.
    Thrombosis and haemostasis, 1996, Volume: 75, Issue:1

    Topics: Anticoagulants; Cross Reactions; Heparin; Humans; Immunoglobulin G; Nadroparin; Thrombocytopenia

1996
Heparin-induced thrombocytopenia: discrepancy between the presence of IgG cross-reacting in vitro with fraxiparine and its successful clinical use.
    Thrombosis and haemostasis, 1995, Volume: 74, Issue:6

    Topics: Cross Reactions; Heparin; Humans; Immunoglobulin G; Nadroparin; Thrombocytopenia; Treatment Outcome

1995
Efficacy of prevention of thromboembolic complications with LMW-heparin in experiment.
    Acta chirurgica Hungarica, 1997, Volume: 36, Issue:1-4

    Topics: Animals; Anticoagulants; Arthroplasty, Replacement, Hip; Disease Models, Animal; Dogs; Factor Xa Inh

1997
[Heparin-induced thrombocytopenia type II].
    Deutsche medizinische Wochenschrift (1946), 1999, Jan-22, Volume: 124, Issue:3

    Topics: Aged; Anticoagulants; Appendectomy; Female; Fibrinolytic Agents; Hirudin Therapy; Hirudins; Humans;

1999
[State of the art: low-molecular-weight heparin and beyond].
    Minerva cardioangiologica, 2000, Volume: 48, Issue:12 Suppl 1

    Topics: Anticoagulants; Biological Availability; Blood Coagulation Factors; Clinical Trials as Topic; Fibrin

2000
[Incidence of heparin-induced thrombocytopenia in patients with 2019 coronavirus disease].
    Medicina clinica, 2020, 11-13, Volume: 155, Issue:9

    Topics: Aged; Aged, 80 and over; Anticoagulants; Betacoronavirus; Coronavirus Infections; COVID-19; Female;

2020
A prospective observational study on the effectiveness and safety of bemiparin, first dose administered 6 h after knee or hip replacement surgery.
    Archives of orthopaedic and trauma surgery, 2007, Volume: 127, Issue:8

    Topics: Aged; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Drug Administ

2007
Evaluation of the effectiveness and safety of bemiparin in a large population of orthopedic patients in a normal clinical practice.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2008, Volume: 14, Issue:1

    Topics: Adult; Aged; Chemoprevention; Dose-Response Relationship, Drug; Drug Evaluation; Female; Hemorrhage;

2008
Heparin Skin Necrosis in Heparin-Induced Thrombocytopenia.
    Mayo Clinic proceedings, 2021, Volume: 96, Issue:9

    Topics: Aged; Anticoagulants; Enoxaparin; Female; Humans; Injections; Necrosis; Skin Diseases; Thrombocytope

2021
Rare presentation of enoxaparin-induced skin necrosis in a postoperative patient.
    BMJ case reports, 2022, Apr-13, Volume: 15, Issue:4

    Topics: Anticoagulants; Enoxaparin; Female; Heparin; Heparin, Low-Molecular-Weight; Humans; Necrosis; Postop

2022
An Open-Label, Single-Arm, Pilot Intervention Study to Assess the Efficacy and Safety of Apixaban in Heparin-Induced Thrombocytopenia.
    Journal of clinical pharmacology, 2022, Volume: 62, Issue:11

    Topics: Anticoagulants; Enoxaparin; Factor Xa Inhibitors; Hemorrhage; Heparin; Humans; Pilot Projects; Pyraz

2022
Heparin-induced thrombocytopenia post-cardiovascular interventional therapy: a case report.
    BMC cardiovascular disorders, 2022, 08-03, Volume: 22, Issue:1

    Topics: Aged; Anticoagulants; Enoxaparin; Heparin; Humans; Male; Platelet Count; Thrombocytopenia

2022
New insights into the binding of PF4 to long heparin oligosaccharides in ultralarge complexes using mass spectrometry.
    Journal of thrombosis and haemostasis : JTH, 2023, Volume: 21, Issue:12

    Topics: Enoxaparin; Heparin; Heparin, Low-Molecular-Weight; Humans; Immunologic Factors; Mass Spectrometry;

2023
Myocardial Infarction with Limb Arterial and Venous Thrombosis in a Patient with Enoxaparin-Induced Thrombocytopenia.
    The American journal of case reports, 2020, May-29, Volume: 21

    Topics: Aged; Antithrombins; Arginine; Enoxaparin; Factor Xa Inhibitors; Female; Humans; Pipecolic Acids; Py

2020
Outcomes with enoxaparin dose reductions during thrombocytopenia in patients with hematopoietic stem cell transplantation (HSCT).
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:6

    Topics: Anticoagulants; Drug Tapering; Enoxaparin; Hematopoietic Stem Cell Transplantation; Humans; Retrospe

2021
A case of Evans syndrome secondary to COVID-19.
    Blood transfusion = Trasfusione del sangue, 2021, Volume: 19, Issue:1

    Topics: Adult; Anemia, Hemolytic, Autoimmune; Anticoagulants; COVID-19; Enoxaparin; Humans; Immunoglobulins,

2021
Routine monitoring for heparin-induced thrombocytopenia following lower limb arthroplasty: Is it necessary? A prospective study in a UK district general hospital.
    Orthopaedics & traumatology, surgery & research : OTSR, 2019, Volume: 105, Issue:3

    Topics: Aged; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Enoxaparin; F

2019
Missed Heparin-Induced Thrombocytopenia (HIT) Diagnosis in a Patient with Acute Stent Thrombosis.
    The American journal of case reports, 2019, May-28, Volume: 20

    Topics: Aged; Anticoagulants; Coronary Artery Disease; Enoxaparin; Heparin; Humans; Male; Percutaneous Coron

2019
Giant thrombus on apical wall of left ventricle due to HIT syndrome after anterior MI.
    Herz, 2014, Volume: 39, Issue:7

    Topics: Anticoagulants; Enoxaparin; Heart Ventricles; Humans; Male; Middle Aged; Myocardial Infarction; Thro

2014
[Bullous hemorrhagic dermatosis induced by heparin: description of 2 new cases].
    Medicina clinica, 2014, Dec-09, Volume: 143, Issue:11

    Topics: Aged; Anticoagulants; Aspirin; Brain Ischemia; Cerebral Hemorrhage; Drug Eruptions; Enoxaparin; Hemo

2014
Active and passive surveillance of enoxaparin generics: a case study relevant to biosimilars.
    Expert opinion on drug safety, 2015, Volume: 14, Issue:3

    Topics: Adverse Drug Reaction Reporting Systems; Anticoagulants; Biosimilar Pharmaceuticals; Drugs, Generic;

2015
Should patients with chronic liver disease receive venous thromboembolism prophylaxis?
    JAAPA : official journal of the American Academy of Physician Assistants, 2015, Volume: 28, Issue:6

    Topics: Anticoagulants; Blood Coagulation Disorders; Enoxaparin; Hemorrhage; Heparin; Hospitalization; Human

2015
An unusual case of enoxaparin induced thrombocytopenia in intensive care unit.
    Annali italiani di chirurgia, 2015, Volume: 86

    Topics: Anticoagulants; Autoantibodies; Drug Substitution; Duodenal Neoplasms; Enoxaparin; Female; Fondapari

2015
Safety of anticoagulation in thrombocytopenic patients with hematologic malignancies: A case series.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2017, Volume: 23, Issue:3

    Topics: Aged; Anticoagulants; Enoxaparin; Female; Hematologic Neoplasms; Hemorrhage; Heparin, Low-Molecular-

2017
Enoxaparin dose reduction for thrombocytopenia in patients with cancer: a quality assessment study.
    Journal of thrombosis and thrombolysis, 2017, Volume: 43, Issue:4

    Topics: Adult; Anticoagulants; Enoxaparin; Female; Guideline Adherence; Hemorrhage; Humans; Male; Neoplasms;

2017
Rivaroxaban--an oral, direct Factor Xa inhibitor--has potential for the management of patients with heparin-induced thrombocytopenia.
    British journal of haematology, 2008, Volume: 143, Issue:1

    Topics: Analysis of Variance; Anticoagulants; Antithrombin III; Arginine; Autoantibodies; Enoxaparin; Flow C

2008
The incidence of heparin-induced thrombocytopenia Type II in patients with subarachnoid hemorrhage treated with heparin versus enoxaparin.
    Journal of neurosurgery, 2009, Volume: 110, Issue:1

    Topics: Aged; Anticoagulants; Cerebral Angiography; Cohort Studies; Enoxaparin; Female; Heparin; Humans; Mal

2009
Once daily enoxaparin for outpatient treatment of acute venous thromboembolism: a case-control study.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2010, Volume: 16, Issue:1

    Topics: Acute Disease; Adult; Aged; Anticoagulants; Case-Control Studies; Enoxaparin; Female; Follow-Up Stud

2010
Bridging of oral anticoagulation with low-molecular-weight heparin: experience in 373 patients with renal insufficiency undergoing invasive procedures.
    Thrombosis and haemostasis, 2009, Volume: 101, Issue:6

    Topics: Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Creatinine; Drug Dosage Calculations;

2009
[Headaches in a 21-year-old man with Goodpasture disease].
    Annales francaises d'anesthesie et de reanimation, 2009, Volume: 28, Issue:9

    Topics: Anti-Glomerular Basement Membrane Disease; Anticoagulants; Chondroitin Sulfates; Combined Modality T

2009
Systemic bleeding in a patient with enoxaparin-induced thrombocytopenia.
    The American journal of emergency medicine, 2009, Volume: 27, Issue:6

    Topics: Aged, 80 and over; Anticoagulants; Enoxaparin; Fatal Outcome; Hemorrhage; Humans; Male; Thrombocytop

2009
[Enoxaparin-induced thrombocytopenia with associated arterial and venous thrombosis].
    Medicina clinica, 2011, Jan-15, Volume: 136, Issue:1

    Topics: Aged, 80 and over; Anticoagulants; Enoxaparin; Femoral Vein; Humans; Male; Thrombocytopenia; Venous

2011
Anti-PF4/heparin antibody formation postorthopedic surgery thromboprophylaxis: the role of non-drug risk factors and evidence for a stoichiometry-based model of immunization.
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:3

    Topics: Antibodies; Anticoagulants; Body Mass Index; Drug Administration Schedule; Enoxaparin; Evidence-Base

2010
Successful surgical management of massive pulmonary embolism during the second trimester in a parturient with heparin-induced thrombocytopenia.
    Interactive cardiovascular and thoracic surgery, 2010, Volume: 11, Issue:5

    Topics: Adult; Anticoagulants; Cardiopulmonary Bypass; Echocardiography, Transesophageal; Embolectomy; Enoxa

2010
[Dermal necrosis as cutaneous manifestation of heparin-induced thrombocytopenia II?].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2011, Volume: 62, Issue:4

    Topics: Anticoagulants; Chromosome Breakage; Chromosome Disorders; Enoxaparin; Female; Humans; Middle Aged;

2011
Pulmonary embolectomy in heparin-induced thrombocytopenia and thrombosis? Safety of heparin use.
    Interactive cardiovascular and thoracic surgery, 2010, Volume: 11, Issue:5

    Topics: Anticoagulants; Cardiopulmonary Bypass; Embolectomy; Enoxaparin; Female; Fondaparinux; Heart Arrest,

2010
Anticoagulant utilization evaluation in a teaching hospital: a prospective study.
    Journal of pharmacy practice, 2010, Volume: 23, Issue:6

    Topics: Adult; Aged; Anticoagulants; Cross-Sectional Studies; Drug Monitoring; Drug Utilization Review; Enox

2010
Perioperative bridging of chronic oral anticoagulation in patients undergoing pacemaker implantation--a study in 200 patients.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2011, Volume: 13, Issue:9

    Topics: Aged; Aged, 80 and over; Anticoagulants; Cardiac Surgical Procedures; Enoxaparin; Female; Heart Fail

2011
Heparin-induced thrombocytopenia: an increasingly common cause of bilateral adrenal hemorrhage.
    Journal of the American Geriatrics Society, 2011, Volume: 59, Issue:6

    Topics: Adrenal Gland Diseases; Adrenal Glands; Adrenal Insufficiency; Aged; Anticoagulants; Arthroplasty, R

2011
Coagulation: cascade!
    Lancet (London, England), 2011, Aug-20, Volume: 378, Issue:9792

    Topics: Aged; Anticoagulants; Coumarins; Enoxaparin; Gangrene; Heparin; Humans; International Normalized Rat

2011
Effectiveness and safety of thromboprophylaxis with enoxaparin in medical inpatients.
    Thrombosis research, 2011, Volume: 128, Issue:5

    Topics: Aged; Comorbidity; Drug-Related Side Effects and Adverse Reactions; Emergency Medical Services; Enox

2011
Binding of heparin-dependent antibodies to PF4 modified by enoxaparin oligosaccharides: evaluation by surface plasmon resonance and serotonin release assay.
    Journal of thrombosis and haemostasis : JTH, 2012, Volume: 10, Issue:3

    Topics: Antibodies; Anticoagulants; Binding Sites, Antibody; Blood Platelets; Case-Control Studies; Enoxapar

2012
Rapid-onset heparin-induced thrombocytopenia without previous heparin exposure.
    Platelets, 2012, Volume: 23, Issue:6

    Topics: Antibodies, Antiphospholipid; Anticoagulants; Antigen-Antibody Complex; Enoxaparin; Extremities; Fem

2012
A giant tumor thrombi filling right ventricle in a thrombocytopenic patient with renal cell carcinoma.
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2012, Apr-20, Volume: 12, Issue:3

    Topics: Anticoagulants; Carcinoma, Renal Cell; Chest Pain; Dyspnea; Echocardiography; Enoxaparin; Heart Vent

2012
Enoxaparin safety in patients with severe thrombocytopenia.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:9

    Topics: Anticoagulants; Bone Marrow Transplantation; Enoxaparin; Humans; Lymphoma, Non-Hodgkin; Male; Middle

2002
A safety analysis of thromboprophylaxis in acute medical illness.
    Thrombosis and haemostasis, 2003, Volume: 89, Issue:3

    Topics: Acute Disease; Anticoagulants; Enoxaparin; Hemorrhage; Heparin; Humans; Risk Factors; Safety; Thromb

2003
[A puzzling circulatory failure after total hip replacement].
    Annales francaises d'anesthesie et de reanimation, 2003, Volume: 22, Issue:9

    Topics: Acute Disease; Adrenal Insufficiency; Anticoagulants; Arthroplasty, Replacement, Hip; Enoxaparin; Fe

2003
Low-molecular-weight heparin-induced thrombocytopenia in a child.
    The Annals of pharmacotherapy, 2004, Volume: 38, Issue:2

    Topics: Anticoagulants; Child; Enoxaparin; Female; Heparin, Low-Molecular-Weight; Hirudins; Humans; Platelet

2004
Gastrointestinal bleeding in an elderly patient with a recent hip replacement.
    Journal of the Mississippi State Medical Association, 2004, Volume: 45, Issue:12

    Topics: Aged; Aged, 80 and over; Anticoagulants; Arthroplasty, Replacement, Hip; Contraindications; Diagnosi

2004
Safety of low-dose low-molecular-weight-heparins in thrombocytopenic stem cell transplantation patients: a case series and review of the literature.
    Bone marrow transplantation, 2005, Volume: 35, Issue:11

    Topics: Adult; Aged; Anticoagulants; Blood Platelets; Bone Marrow Transplantation; Cohort Studies; Enoxapari

2005
Early-onset heparin-induced thrombocytopenia after a 165-day heparin-free interval: case report and review of the literature.
    Pharmacotherapy, 2005, Volume: 25, Issue:4

    Topics: Aged; Anticoagulants; Enoxaparin; Humans; Male; Thrombocytopenia; Time Factors

2005
Three cases of anicteric leptospirosis from Turkey: mild to severe complications.
    The Journal of infection, 2006, Volume: 52, Issue:2

    Topics: Acute Kidney Injury; Acyclovir; Adult; Aged; Agglutination Tests; Ampicillin; Anti-Bacterial Agents;

2006
Two cases of heparin induced thrombocytopenia type II post cardiopulmonary bypass.
    Anaesthesia and intensive care, 2006, Volume: 34, Issue:1

    Topics: Aged; Angina, Unstable; Cardiopulmonary Bypass; Enoxaparin; Female; Follow-Up Studies; Humans; Male;

2006
Anti-metastatic effect of a non-anticoagulant low-molecular-weight heparin versus the standard low-molecular-weight heparin, enoxaparin.
    Thrombosis and haemostasis, 2006, Volume: 96, Issue:6

    Topics: Animals; Anticoagulants; Antineoplastic Agents; Blood Coagulation; Cell Line, Tumor; Dose-Response R

2006
Unfractionated- versus low-molecular-weight-heparin-associated HIT in hospitalized medical patients.
    Journal of hospital medicine, 2006, Volume: 1, Issue:6

    Topics: Enoxaparin; Heparin, Low-Molecular-Weight; Hospitalization; Humans; Randomized Controlled Trials as

2006
[Perioperative Bridging with Enoxaparin. Results of the Prospective BRAVE Registry with 779 Patients].
    Medizinische Klinik (Munich, Germany : 1983), 2007, Oct-15, Volume: 102, Issue:10

    Topics: Aged; Aged, 80 and over; Anticoagulants; Dose-Response Relationship, Drug; Drug Administration Sched

2007
Cost and occurrence of thrombocytopenia in patients receiving venous thromboembolism prophylaxis following major orthopaedic surgeries.
    Journal of thrombosis and thrombolysis, 2008, Volume: 26, Issue:2

    Topics: Aged; Anticoagulants; Cohort Studies; Dalteparin; Enoxaparin; Female; Fondaparinux; Health Care Cost

2008
Heparin-induced thrombocytopenia in a patient with lung embolism and left-sided pneumonia: a case report.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2007, Volume: 58 Suppl 5, Issue:Pt 1

    Topics: Aged; Antibodies; Anticoagulants; Enoxaparin; Female; Humans; Platelet Factor 4; Pneumonia; Pulmonar

2007
Cutaneous microangiopathic thrombosis complicated by pyoderma gangrenosum in post-cardiac surgery heparin-induced thrombocytopaenia.
    Heart, lung & circulation, 2009, Volume: 18, Issue:4

    Topics: Aged; Aortic Valve Stenosis; Autoantibodies; Cardiopulmonary Bypass; Enoxaparin; Female; Fibrinolyti

2009
Heparin-induced thrombocytopenia and paradoxical venous thromboses.
    Israel journal of medical sciences, 1993, Volume: 29, Issue:8

    Topics: Aged; Axillary Vein; Coronary Disease; Diabetes Mellitus, Type 2; Enoxaparin; Female; Femoral Vein;

1993
Thrombocytopenia, antithrombin deficiency and extensive thromboembolism in pregnancy: treatment with low-molecular-weight heparin.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 1995, Volume: 6, Issue:7

    Topics: Adult; Antithrombin III; Antithrombin III Deficiency; Enoxaparin; Female; Fetal Death; Heparin; Huma

1995
Use of enoxaparin in patients with heparin-induced thrombocytopenia syndrome.
    Journal of vascular surgery, 1996, Volume: 23, Issue:5

    Topics: Aged; Antibodies; Anticoagulants; Blood Platelets; Enoxaparin; Evaluation Studies as Topic; Female;

1996
Cardiopulmonary bypass for heparin-induced thrombocytopenia: management with a heparin-bonded circuit and enoxaparin.
    The Journal of thoracic and cardiovascular surgery, 1996, Volume: 112, Issue:5

    Topics: Aged; Anticoagulants; Cardiopulmonary Bypass; Coronary Disease; Enoxaparin; Heparin; Humans; Male; T

1996
Enoxaparin (Clexane) HITS.
    Anaesthesia and intensive care, 1996, Volume: 24, Issue:5

    Topics: Antibodies; Anticoagulants; Enoxaparin; Female; Heparin, Low-Molecular-Weight; Humans; Platelet Aggr

1996
Enoxaparin-associated dermal necrosis: a consequence of cross-reactivity with heparin-mediated antibodies.
    The Annals of pharmacotherapy, 1997, Volume: 31, Issue:3

    Topics: Adult; Antibodies; Anticoagulants; Cross Reactions; Drug Eruptions; Enoxaparin; Female; Heparin; Hum

1997
Enoxaparin (Clexane) HITS.
    Anaesthesia and intensive care, 1996, Volume: 24, Issue:2

    Topics: Anticoagulants; Blood Loss, Surgical; Enoxaparin; Female; Humans; Knee Prosthesis; Middle Aged; Post

1996
Treatment of heparin-induced thrombocytopenia.
    The Journal of thoracic and cardiovascular surgery, 1997, Volume: 114, Issue:3

    Topics: Anticoagulants; Chondroitin Sulfates; Dermatan Sulfate; Enoxaparin; Heparin; Heparinoids; Heparitin

1997
Heparin-induced thrombocytopenia presenting after the cessation of low molecular weight heparin prophylaxis with enoxaparin.
    The Medical journal of Australia, 2000, May-01, Volume: 172, Issue:9

    Topics: Anticoagulants; Chondroitin Sulfates; Dermatan Sulfate; Drug Combinations; Enoxaparin; Female; Hepar

2000
Venous thromboembolism during pregnancy: a retrospective study of enoxaparin safety in 624 pregnancies.
    BJOG : an international journal of obstetrics and gynaecology, 2001, Volume: 108, Issue:11

    Topics: Adult; Anticoagulants; Cerebral Hemorrhage; Enoxaparin; Female; Humans; Infant, Newborn; Intracrania

2001
[Heparin-induced thrombocytopenia in patients and prevention with low molecular weight heparin].
    Sbornik lekarsky, 2001, Volume: 102, Issue:3

    Topics: Abdomen; Adult; Aged; Aged, 80 and over; Anticoagulants; Enoxaparin; Female; Heparin; Humans; Male;

2001
Biochemical and pharmacologic profile of low molecular weight heparin (LU 47311, Clivarin).
    Seminars in thrombosis and hemostasis, 1993, Volume: 19 Suppl 1

    Topics: Animals; Bleeding Time; Hemorrhage; Heparin, Low-Molecular-Weight; Humans; Male; Molecular Weight; P

1993
Delayed-onset heparin-induced skin necrosis: a rare complication of perioperative heparin therapy.
    BMJ case reports, 2017, Nov-03, Volume: 2017

    Topics: Aged, 80 and over; Anticoagulants; Arthroplasty, Replacement, Hip; Dalteparin; Diagnosis, Differenti

2017
Heparin-induced thrombocytopenia following hip and knee arthroplasty.
    British journal of haematology, 2013, Volume: 161, Issue:2

    Topics: Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Dalteparin; Female;

2013
Fondaparinux as alternative anticoagulant to warfarin or low-molecular-weight heparin for recurrent venous thrombosis.
    The Annals of pharmacotherapy, 2014, Volume: 48, Issue:3

    Topics: Adult; Anticoagulants; Dalteparin; Fondaparinux; Heparin, Low-Molecular-Weight; Humans; Injections,

2014
Antithrombotic therapy in patients with thrombocytopenic cancer: outcomes associated with reduced-dose, low-molecular-weight heparin during hospitalization.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2014, Volume: 20, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Blood Transfusion; Dalteparin; Female; Fibrinolytic Agents; Hospital

2014
Cost-effectiveness of dalteparin vs unfractionated heparin for the prevention of venous thromboembolism in critically ill patients.
    JAMA, 2014, Nov-26, Volume: 312, Issue:20

    Topics: Anticoagulants; Cost-Benefit Analysis; Critical Illness; Dalteparin; Female; Health Expenditures; He

2014
Severe and persistent heparin-induced thrombocytopenia despite fondaparinux treatment.
    American journal of hematology, 2015, Volume: 90, Issue:7

    Topics: Aged, 80 and over; Antibodies; Anticoagulants; Blood Platelets; Dalteparin; Female; Fondaparinux; Hi

2015
Argatroban for Treatment of Heparin-Induced Thrombocytopenia and Thrombosis in a Patient with Multiple Myeloma Undergoing Hemodialysis.
    Journal of the American Geriatrics Society, 2016, Volume: 64, Issue:8

    Topics: Aged, 80 and over; Anticoagulants; Antithrombins; Arginine; Dalteparin; Female; Humans; Multiple Mye

2016
Dalteparin in critically ill patients.
    The New England journal of medicine, 2011, 07-14, Volume: 365, Issue:2

    Topics: Anticoagulants; Critical Illness; Dalteparin; Heparin; Humans; Thrombocytopenia; Venous Thrombosis

2011
42-year-old man with hemoptysis, dyspnea, and orthopnea.
    Mayo Clinic proceedings, 2012, Volume: 87, Issue:5

    Topics: Adult; Anticoagulants; Dalteparin; Diagnosis, Differential; Dyspnea; Hemoptysis; Humans; Male; Mitra

2012
[Dalteparin induced thrombocytopenia. Study of a case].
    Medicina clinica, 2002, Sep-28, Volume: 119, Issue:10

    Topics: Aged; Aged, 80 and over; Anticoagulants; Dalteparin; Female; Humans; Thrombocytopenia

2002
Cutaneous dalteparin reactions associated with antibodies of heparin-induced thrombocytopenia.
    The Annals of pharmacotherapy, 2003, Volume: 37, Issue:5

    Topics: Antibodies; Dalteparin; Humans; Male; Middle Aged; Skin; Skin Diseases; Thrombocytopenia; Warfarin

2003
Dalteparin compared with an oral anticoagulant for thromboprophylaxis in patients with cancer.
    The New England journal of medicine, 2003, Oct-02, Volume: 349, Issue:14

    Topics: Acenocoumarol; Administration, Oral; Anticoagulants; Bias; Dalteparin; Humans; International Normali

2003
Fixed-dose low-molecular-weight heparin for secondary prevention of venous thromboembolism in patients with disseminated cancer: a prospective cohort study.
    Journal of thrombosis and haemostasis : JTH, 2004, Volume: 2, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Blood Platelets; Body Weight; Brain Neoplasms; Cohor

2004
[Successful therapy of heparin-associated thrombocytopenia with a low sulfated heparinoid].
    Geburtshilfe und Frauenheilkunde, 1995, Volume: 55, Issue:3

    Topics: Adult; Anticoagulants; Cesarean Section; Chondroitin Sulfates; Cross Reactions; Dalteparin; Dermatan

1995
Can low molecular weight heparins and heparinoids be safely given to patients with heparin-induced thrombocytopenia syndrome?
    Surgery, 1993, Volume: 114, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies; Chondroitin Sulfates; Dalteparin; Dermatan S

1993
Heparin-induced thrombocytopenia and heart operation: management with tedelparin.
    The Annals of thoracic surgery, 1995, Volume: 59, Issue:2

    Topics: Cardiopulmonary Bypass; Dalteparin; Female; Heart Valve Prosthesis; Heparin; Humans; Middle Aged; Mi

1995
Heparin-induced thrombocytopenia: cross-reactivity between standard heparin, low molecular weight heparin, dalteparin (Fragmin) and heparinoid, danaparoid (Orgaran).
    British journal of haematology, 1995, Volume: 91, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Chondroitin Sulfates; Dalteparin; Dermatan Sulfate; Drug Interaction

1995
Management of heparin-associated thrombocytopenia in pregnancy with subcutaneous r-hirudin.
    Gynecologic and obstetric investigation, 2000, Volume: 49, Issue:1

    Topics: Adult; Anticoagulants; Antithrombins; Dalteparin; Female; Heparin; Hirudin Therapy; Humans; Lupus Er

2000
Heparin-induced thrombocytopenia type II on hemodialysis: switch to danaparoid.
    Pediatric nephrology (Berlin, Germany), 2000, Volume: 14, Issue:8-9

    Topics: Adolescent; Anticoagulants; Child; Chondroitin Sulfates; Dalteparin; Dermatan Sulfate; Drug Combinat

2000
Recombinant factor VIIa (Novoseven) restores deficient coagulation: experience from an ex vivo model.
    Seminars in hematology, 2001, Volume: 38, Issue:4 Suppl 12

    Topics: Adult; Anticoagulants; Blood Coagulation; Blood Platelets; Coagulants; Dalteparin; Factor VII; Facto

2001
Tinzaparin safety and efficacy in pregnancy.
    Irish journal of medical science, 2014, Volume: 183, Issue:2

    Topics: Abortion, Habitual; Adolescent; Adult; Drug Hypersensitivity; Female; Fibrinolytic Agents; Hemorrhag

2014
[Erythema after subcutaneous heparin treatment].
    Nederlands tijdschrift voor geneeskunde, 2015, Volume: 159

    Topics: Adult; Anticoagulants; Female; Fondaparinux; Heparin, Low-Molecular-Weight; Humans; Platelet Count;

2015
Management dilemma of cardiopulmonary bypass in patients with type II heparin-induced thrombocytopenia.
    British journal of haematology, 2002, Volume: 119, Issue:3

    Topics: Aged; Axillary Vein; Cardiopulmonary Bypass; Female; Fibrinolytic Agents; Heart Atria; Heart Neoplas

2002
Antimetastatic effect of tinzaparin, a low-molecular-weight heparin.
    Journal of thrombosis and haemostasis : JTH, 2003, Volume: 1, Issue:9

    Topics: Animals; Endothelium, Vascular; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Humans; Lipoprot

2003
Recurrent arterial thromboses in a woman with heparin induced thrombocytopenia, successfully managed with iloprost followed by clopidogrel. An alternative therapeutic option for heparin induced thrombocytopenia type II syndrome.
    International angiology : a journal of the International Union of Angiology, 2006, Volume: 25, Issue:1

    Topics: Aged; Arterial Occlusive Diseases; Clopidogrel; Drug Therapy, Combination; Female; Fibrinolytic Agen

2006
Ardeparin and danaparoid for prevention of deep vein thrombosis.
    The Medical letter on drugs and therapeutics, 1997, Oct-10, Volume: 39, Issue:1011

    Topics: Abdomen; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Chondroiti

1997