dalteparin has been researched along with Subarachnoid Hemorrhage in 14 studies
Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)
Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nimodipine (Nimotop), HMG Co-A reductase inhibitor (statins) and enoxaparin (Lovenox) were the only drugs with level-1 evidence available for the treatment of vasospasm from aneurysmal subarachnoid hemorrhage as defined by the US Preventative Services Task Force." | 4.85 | Evidence-based pharmacotherapy for cerebral vasospasm. ( Boulos, AS; Deshaies, EM; Drazin, D; Popp, AJ, 2009) |
| "After undergoing surgery for a ruptured aneurysm, 170 patients were randomized in a prospective, double-blind, placebo-controlled trial to test the effect of enoxaparin on the occurrence of ischemic lesions, which were demonstrated on follow-up CT scans available for 156 patients." | 2.71 | Risk factors for ischemic lesions following aneurysmal subarachnoid hemorrhage. ( Juvela, S; Porras, M; Poussa, K; Siironen, J; Varis, J, 2005) |
| "It presents as an acute spinal cord compression and usually requires emergency surgical decompression." | 2.48 | [Spontaneous resolution of a paraparesis due to a dorsolumbar epidural haematoma associated with subarachnoid anaesthesia and postoperative analgesia using an epidural catheter]. ( Alemán Martín, A; Coronado Hijón, V; Jiménez Delgado, P; Sánchez Gutiérrez, C, 2012) |
| "Delayed cerebral ischemia (DCI) is one of the major causes of delayed morbidity and mortality in patients with aneurysmal subarachnoid hemorrhage (aSAH)." | 1.48 | High-Dose Nadroparin Following Endovascular Aneurysm Treatment Benefits Outcome After Aneurysmal Subarachnoid Hemorrhage. ( Berg, RVD; Coert, BA; Post, R; Vandertop, WP; Verbaan, D; Zijlstra, IAJ, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 9 (64.29) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Post, R | 1 |
| Zijlstra, IAJ | 1 |
| Berg, RVD | 1 |
| Coert, BA | 1 |
| Verbaan, D | 1 |
| Vandertop, WP | 1 |
| Llau, JV | 1 |
| Hoyas, L | 1 |
| Ezpeleta, J | 1 |
| García-Polit, J | 1 |
| Kim, GH | 1 |
| Hahn, DK | 1 |
| Kellner, CP | 1 |
| Komotar, RJ | 1 |
| Starke, R | 1 |
| Garrett, MC | 1 |
| Yao, J | 1 |
| Cleveland, J | 1 |
| Mayer, SA | 1 |
| Connolly, ES | 1 |
| Deshaies, EM | 1 |
| Boulos, AS | 1 |
| Drazin, D | 1 |
| Popp, AJ | 1 |
| Kim, KS | 1 |
| Brophy, GM | 1 |
| Hegazi, MO | 1 |
| Ahmed, S | 1 |
| Sakr, MG | 1 |
| Hassanien, OA | 1 |
| Sánchez Gutiérrez, C | 1 |
| Alemán Martín, A | 1 |
| Coronado Hijón, V | 1 |
| Jiménez Delgado, P | 1 |
| Siironen, J | 4 |
| Juvela, S | 4 |
| Varis, J | 3 |
| Porras, M | 3 |
| Poussa, K | 2 |
| Ilveskero, S | 2 |
| Hernesniemi, J | 1 |
| Lassila, R | 2 |
| Wurm, G | 1 |
| Tomancok, B | 1 |
| Nussbaumer, K | 1 |
| Adelwöhrer, C | 1 |
| Holl, K | 1 |
| Vilkki, JS | 1 |
| Ilvonen, T | 1 |
| Hans, GA | 1 |
| Senard, M | 1 |
| Ledoux, D | 1 |
| Grayet, B | 1 |
| Scholtes, F | 1 |
| Creemers, E | 1 |
| Lamy, ML | 1 |
| Sternlo, JE | 1 |
| Hybbinette, CH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Improving Outcome in Subarachnoid Hemorrhage wIth Nadroparine[NCT04507178] | Phase 2 | 100 participants (Anticipated) | Interventional | 2022-02-02 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for dalteparin and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
Evidence-based pharmacotherapy for cerebral vasospasm.
Topics: Animals; Cardiovascular Agents; Enoxaparin; Evidence-Based Medicine; Humans; Hydroxymethylglutaryl-C | 2009 |
[Spontaneous resolution of a paraparesis due to a dorsolumbar epidural haematoma associated with subarachnoid anaesthesia and postoperative analgesia using an epidural catheter].
Topics: Aged; Analgesia, Epidural; Anesthesia, Epidural; Anesthesia, Spinal; Anticoagulants; Arthroplasty, R | 2012 |
5 trials available for dalteparin and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
No effect of enoxaparin on outcome of aneurysmal subarachnoid hemorrhage: a randomized, double-blind, placebo-controlled clinical trial.
Topics: Aneurysm, Ruptured; Anticoagulants; Combined Modality Therapy; Double-Blind Method; Enoxaparin; Fema | 2003 |
Reduction of ischemic sequelae following spontaneous subarachnoid hemorrhage: a double-blind, randomized comparison of enoxaparin versus placebo.
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Brain Ischemia; Cerebral Infarction; Double-Blind Me | 2004 |
Relationship of local infarctions to cognitive and psychosocial impairments after aneurysmal subarachnoid hemorrhage.
Topics: Cerebral Infarction; Double-Blind Method; Enoxaparin; Female; Humans; Male; Middle Aged; Neuropsycho | 2004 |
Risk factors for ischemic lesions following aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Aneurysm, Ruptured; Anticoagulants; Cerebral Infarction; Double-Blind Method; Enoxapari | 2005 |
D-dimer predicts outcome after aneurysmal subarachnoid hemorrhage: no effect of thromboprophylaxis on coagulation activity.
Topics: Blood Coagulation; Blood Coagulation Tests; Enoxaparin; Female; Fibrin Fibrinogen Degradation Produc | 2005 |
7 other studies available for dalteparin and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
High-Dose Nadroparin Following Endovascular Aneurysm Treatment Benefits Outcome After Aneurysmal Subarachnoid Hemorrhage.
Topics: Adult; Aged; Aneurysm, Ruptured; Brain Ischemia; Embolization, Therapeutic; Endovascular Procedures; | 2018 |
[Use of low molecular weight heparins].
Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Anticoagulants; Antithrombin III Deficiency; Cesarean | 1997 |
The incidence of heparin-induced thrombocytopenia Type II in patients with subarachnoid hemorrhage treated with heparin versus enoxaparin.
Topics: Aged; Anticoagulants; Cerebral Angiography; Cohort Studies; Enoxaparin; Female; Heparin; Humans; Mal | 2009 |
Symptomatic venous thromboembolism: incidence and risk factors in patients with spontaneous or traumatic intracranial hemorrhage.
Topics: Adult; Aged; Anticoagulants; Critical Care; Enoxaparin; Female; Humans; Incidence; Length of Stay; M | 2009 |
Anticoagulation for cerebral venous thrombosis with subarachnoid hemorrhage: a case report.
Topics: Adult; Enoxaparin; Female; Fibrinolytic Agents; Humans; Lateral Sinus Thrombosis; Magnetic Resonance | 2010 |
Cerebral subarachnoid blood migration consecutive to a lumbar haematoma after spinal anaesthesia.
Topics: Aged; Anesthesia, Spinal; Anesthetics, Intravenous; Anesthetics, Local; Angioplasty, Balloon; Arteri | 2008 |
Spinal subdural bleeding after attempted epidural and subsequent spinal anaesthesia in a patient on thromboprophylaxis with low molecular weight heparin.
Topics: Aged; Anesthesia, Epidural; Anesthesia, Spinal; Enoxaparin; Female; Hematoma, Epidural, Cranial; Hem | 1995 |