Page last updated: 2024-10-18

dalteparin and Right Ventricular Dysfunction

dalteparin has been researched along with Right Ventricular Dysfunction in 4 studies

Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)

Research Excerpts

ExcerptRelevanceReference
"Tirofiban was administered for 24 h and the IABP was withdrawn after 60 h."5.35Reversible clopidogrel resistance due to right ventricular myocardial infarction: risk factor of recurrent stent thrombosis? ( Braun-Dullaeus, RC; Hass, N; Ibrahim, K; Kolschmann, S; Strasser, RH, 2008)
"There were not differences on pulmonary embolism extension, (P 0."2.74Improving adjunctive treatment in pulmonary embolism and fibrinolytic therapy. The role of enoxaparin and weight-adjusted unfractionated heparin. ( Archondo, T; Arriaga, R; Bermudez, M; Castillo, F; Comparan-Nuñez, A; Garcia, H; Garcia, J; Garcia-Sosa, A; Garza, A; Gutierrez, J; Hernandez, JM; Jasso, O; Jerjes-Sánchez, C; Martinez, P; Miguel-Canseco, L; Ramírez-Rivera, A; Rangel, F; Reyes, E; Villarreal-Umaña, S, 2009)
"Acute pulmonary embolism (APE) causes right ventricular dysfunction (RVD)."2.73Value of transthoracic echocardiography in therapy regimens evaluation in pulmonary embolism. ( Dai, H; Pang, B; Tong, Z; Wang, C; Wu, Y; Yang, Y; Zhai, Z; Zhu, L, 2008)
"We randomized 60 symptomatic pulmonary embolism patients in a 2:1 ratio to 90 days of enoxaparin as monotherapy without warfarin (N=40) or to intravenous unfractionated heparin as a "bridge" to warfarin, target INR 2."2.71Enoxaparin monotherapy without oral anticoagulation to treat acute symptomatic pulmonary embolism. ( Beckman, JA; Dunn, K; Goldhaber, SZ; Sasahara, AA, 2003)
"Tirofiban was administered for 24 h and the IABP was withdrawn after 60 h."1.35Reversible clopidogrel resistance due to right ventricular myocardial infarction: risk factor of recurrent stent thrombosis? ( Braun-Dullaeus, RC; Hass, N; Ibrahim, K; Kolschmann, S; Strasser, RH, 2008)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhu, L1
Wang, C1
Yang, Y1
Wu, Y1
Zhai, Z1
Dai, H1
Pang, B1
Tong, Z1
Ibrahim, K1
Hass, N1
Kolschmann, S1
Strasser, RH1
Braun-Dullaeus, RC1
Beckman, JA1
Dunn, K1
Sasahara, AA1
Goldhaber, SZ1
Jerjes-Sánchez, C1
Villarreal-Umaña, S1
Ramírez-Rivera, A1
Garcia-Sosa, A1
Miguel-Canseco, L1
Archondo, T1
Reyes, E1
Garza, A1
Arriaga, R1
Castillo, F1
Jasso, O1
Garcia, H1
Bermudez, M1
Hernandez, JM1
Garcia, J1
Martinez, P1
Rangel, F1
Gutierrez, J1
Comparan-Nuñez, A1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy and Safety Evaluation of Recombinant Streptokinase and Urokinase in the Treatment of Pulmonary Embolism: A Multi-Center, Randomized Controlled Trial in China[NCT00968929]Phase 483 participants (Actual)Interventional2006-06-30Completed
Efficacy and Safety Evaluation of Low Dosage of Recombinant Tissue Plasminogen Activator (rt-PA) in the Treatment of Pulmonary Thromboembolism: A Multi-Center, Randomized Controlled Trial in China[NCT00781378]Phase 4118 participants (Actual)Interventional2002-06-30Completed
Efficacy and Safety of Body Weight Adjusted Nadroparin vs Standard Unfractionated Heparin for the Initial Treatment of Pulmonary Thromboembolism:a Multi-Centre, Randomised Controlled Trial in China[NCT00796692]Phase 4274 participants (Actual)Interventional2002-06-30Completed
Efficacy and Safety Evaluation of 12-h and 2-h Urokinase Regimes in the Treatment of Pulmonary Thromboembolism: A Multi-Center, Randomized Controlled Trial in China[NCT00799968]Phase 4129 participants (Actual)Interventional2002-06-30Completed
Once Daily Enoxaparin for Outpatient Treatment of Acute Deep Venous Thrombosis and/or Pulmonary Embolism[NCT00413374]40 participants (Actual)Interventional2006-05-31Completed
[NCT01956955]Phase 4150 participants (Anticipated)Interventional2011-01-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Death

All-cause mortality (NCT00413374)
Timeframe: 30 Days

InterventionParticipants (Count of Participants)
Enoxaparin 1.5 mg/kg Once Daily0
Enoxaparin 1 mg/kg Twice Daily0

Major Bleeding Complication

Major bleeding complication as defined as spinal, retroperitoneal, or intracranial bleeding; drop in hemoglobin ≥2g/dl or transfusion ≥2U or surgical or medical intervention, death related to bleeding. (NCT00413374)
Timeframe: 30 Days

Interventionparticipants (Number)
Enoxaparin 1.5 mg/kg Daily0
Enoxaparin 1 mg/kg Twice Daily3

Recurrent VTE

Major clotting complication (recurrent VTE) as defined as recurrent acute pulmonary embolism confirmed on chest CT or recurrent deep vein thrombosis in the contralateral extremity confirmed with venous ultrasound or CT scan while on once daily enoxaparin therapy. (NCT00413374)
Timeframe: 30 Days

Interventionparticipants (Number)
Enoxaparin 1.5 mg/kg Daily1
Enoxaparin 1 mg/kg Twice Daily3

Trials

3 trials available for dalteparin and Right Ventricular Dysfunction

ArticleYear
Value of transthoracic echocardiography in therapy regimens evaluation in pulmonary embolism.
    Journal of thrombosis and thrombolysis, 2008, Volume: 26, Issue:3

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Echocardiography; Female; Fibrinolytic Agents; Humans

2008
Value of transthoracic echocardiography in therapy regimens evaluation in pulmonary embolism.
    Journal of thrombosis and thrombolysis, 2008, Volume: 26, Issue:3

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Echocardiography; Female; Fibrinolytic Agents; Humans

2008
Value of transthoracic echocardiography in therapy regimens evaluation in pulmonary embolism.
    Journal of thrombosis and thrombolysis, 2008, Volume: 26, Issue:3

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Echocardiography; Female; Fibrinolytic Agents; Humans

2008
Value of transthoracic echocardiography in therapy regimens evaluation in pulmonary embolism.
    Journal of thrombosis and thrombolysis, 2008, Volume: 26, Issue:3

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Echocardiography; Female; Fibrinolytic Agents; Humans

2008
Value of transthoracic echocardiography in therapy regimens evaluation in pulmonary embolism.
    Journal of thrombosis and thrombolysis, 2008, Volume: 26, Issue:3

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Echocardiography; Female; Fibrinolytic Agents; Humans

2008
Value of transthoracic echocardiography in therapy regimens evaluation in pulmonary embolism.
    Journal of thrombosis and thrombolysis, 2008, Volume: 26, Issue:3

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Echocardiography; Female; Fibrinolytic Agents; Humans

2008
Value of transthoracic echocardiography in therapy regimens evaluation in pulmonary embolism.
    Journal of thrombosis and thrombolysis, 2008, Volume: 26, Issue:3

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Echocardiography; Female; Fibrinolytic Agents; Humans

2008
Value of transthoracic echocardiography in therapy regimens evaluation in pulmonary embolism.
    Journal of thrombosis and thrombolysis, 2008, Volume: 26, Issue:3

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Echocardiography; Female; Fibrinolytic Agents; Humans

2008
Value of transthoracic echocardiography in therapy regimens evaluation in pulmonary embolism.
    Journal of thrombosis and thrombolysis, 2008, Volume: 26, Issue:3

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Echocardiography; Female; Fibrinolytic Agents; Humans

2008
Value of transthoracic echocardiography in therapy regimens evaluation in pulmonary embolism.
    Journal of thrombosis and thrombolysis, 2008, Volume: 26, Issue:3

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Echocardiography; Female; Fibrinolytic Agents; Humans

2008
Value of transthoracic echocardiography in therapy regimens evaluation in pulmonary embolism.
    Journal of thrombosis and thrombolysis, 2008, Volume: 26, Issue:3

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Echocardiography; Female; Fibrinolytic Agents; Humans

2008
Value of transthoracic echocardiography in therapy regimens evaluation in pulmonary embolism.
    Journal of thrombosis and thrombolysis, 2008, Volume: 26, Issue:3

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Echocardiography; Female; Fibrinolytic Agents; Humans

2008
Value of transthoracic echocardiography in therapy regimens evaluation in pulmonary embolism.
    Journal of thrombosis and thrombolysis, 2008, Volume: 26, Issue:3

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Echocardiography; Female; Fibrinolytic Agents; Humans

2008
Value of transthoracic echocardiography in therapy regimens evaluation in pulmonary embolism.
    Journal of thrombosis and thrombolysis, 2008, Volume: 26, Issue:3

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Echocardiography; Female; Fibrinolytic Agents; Humans

2008
Value of transthoracic echocardiography in therapy regimens evaluation in pulmonary embolism.
    Journal of thrombosis and thrombolysis, 2008, Volume: 26, Issue:3

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Echocardiography; Female; Fibrinolytic Agents; Humans

2008
Value of transthoracic echocardiography in therapy regimens evaluation in pulmonary embolism.
    Journal of thrombosis and thrombolysis, 2008, Volume: 26, Issue:3

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Echocardiography; Female; Fibrinolytic Agents; Humans

2008
Enoxaparin monotherapy without oral anticoagulation to treat acute symptomatic pulmonary embolism.
    Thrombosis and haemostasis, 2003, Volume: 89, Issue:6

    Topics: Acute Disease; Adult; Aged; Enoxaparin; Feasibility Studies; Female; Hemorrhage; Heparin; Humans; Le

2003
Improving adjunctive treatment in pulmonary embolism and fibrinolytic therapy. The role of enoxaparin and weight-adjusted unfractionated heparin.
    Journal of thrombosis and thrombolysis, 2009, Volume: 27, Issue:2

    Topics: Adult; Aged; Anticoagulants; Drug Therapy, Combination; Enoxaparin; Female; Heparin; Hospital Mortal

2009

Other Studies

1 other study available for dalteparin and Right Ventricular Dysfunction

ArticleYear
Reversible clopidogrel resistance due to right ventricular myocardial infarction: risk factor of recurrent stent thrombosis?
    Clinical research in cardiology : official journal of the German Cardiac Society, 2008, Volume: 97, Issue:11

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Stenosis; Coronary Thrombosis; Drug R

2008