dalteparin has been researched along with Pain in 20 studies
Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dalteparin is superior to the NSAID ibuprofen in preventing extension of superficial thrombophlebitis during the 14-day treatment period with similar relief of pain and no increase in bleeding." | 9.16 | A randomized trial of dalteparin compared with ibuprofen for the treatment of superficial thrombophlebitis. ( Aston, CE; Rathbun, SW; Whitsett, TL, 2012) |
| "Dalteparin is superior to the NSAID ibuprofen in preventing extension of superficial thrombophlebitis during the 14-day treatment period with similar relief of pain and no increase in bleeding." | 5.16 | A randomized trial of dalteparin compared with ibuprofen for the treatment of superficial thrombophlebitis. ( Aston, CE; Rathbun, SW; Whitsett, TL, 2012) |
| "Suspecting typhoid fever with ciprofloxacin was started." | 3.71 | [Fever and calf tenderness after travel in Thailand: murine typhus and deep vein thrombosis]. ( Döller, PC; Slesak, G, 2001) |
| "Pain was assessed using visual analogue scale at inclusion, one and six weeks." | 2.90 | Effect of anticoagulant treatment on pain in distal deep vein thrombosis: an ancillary analysis from the cactus trial. ( Blondon, M; Diamand, JM; Frappe, P; Galanaud, JP; Glauser, F; Kahn, SR; Le Gal, G; Ouvry, P; Quere, I; Righini, M; Robert-Ebadi, H; Tissot, A, 2019) |
| "Pain was assessed with a 10-unit numeric scale." | 2.70 | Comparison of two needle sizes for subcutaneous administration of enoxaparin: effects on size of hematomas and pain on injection. ( Kanji, Z; Robb, DM, 2002) |
| "Pain was assessed by visual analogue and verbal category scales." | 2.67 | Clinical evaluation of pain during subcutaneous injections of low molecular weight heparins in healthy volunteers. ( Billon, N; Funck-Brentano, C; Gloaguen, F; Jaillon, P, 1994) |
| "Pain is the most prominent symptom of vasoocclusion, and hypercoagulability is a well-established pathogenic phenomenon in people with sickle cell disease." | 2.50 | Low-molecular-weight heparins for managing vasoocclusive crises in people with sickle cell disease: a summary of a cochrane systematic review. ( Fedorowicz, Z; van Zuuren, EJ, 2014) |
| "Infective endocarditis is associated with significant morbidity and mortality, despite advances in diagnosis and treatment strategies." | 1.51 | No Fever, No Murmur, No Problem? A Concealed Case of Infective Endocarditis. ( Gorman, M; McCann, M; McKeown, B, 2019) |
| "Antiphospholipid syndrome is an autoimmune disease characterized by vascular thrombosis involving both the arterial and venous systems that can lead to tissue ischemia or end-organ damage." | 1.51 | The Solitary Blue Toe: A Unique Presentation of Antiphospholipid Syndrome. ( Dimond, DG; Driscoll, K; Kiser, C; Lam, JK; Razzante, M; Wurster, L, 2019) |
| "With patients in whom it is indicated, the home therapy ankle pathway has proved to be a safe and resource sparing method of managing ankle fractures prior to surgery." | 1.39 | Home therapy pathway - safe and streamlined method of initial management of ankle fractures. ( Baraza, N; Dhukaram, V; Lever, S, 2013) |
| "Venous thrombosis is a very rare occurrence in patients with haemophilia A." | 1.31 | Thrombosis in a duplicated superficial femoral vein in a patient with haemophilia A. ( Allan, PL; Dennis, R; Ludlam, CA; Manson, LM; Stewart, AJ, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 9 (45.00) | 29.6817 |
| 2010's | 10 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Righini, M | 1 |
| Robert-Ebadi, H | 1 |
| Glauser, F | 1 |
| Blondon, M | 1 |
| Ouvry, P | 1 |
| Diamand, JM | 1 |
| Tissot, A | 1 |
| Frappe, P | 1 |
| Quere, I | 1 |
| Kahn, SR | 1 |
| Galanaud, JP | 1 |
| Le Gal, G | 1 |
| Uncu, H | 1 |
| Billon, N | 1 |
| Gloaguen, F | 1 |
| Funck-Brentano, C | 1 |
| Jaillon, P | 1 |
| Tan, XC | 1 |
| Nalavenkata, S | 1 |
| Yunaev, M | 1 |
| McCann, M | 1 |
| Gorman, M | 1 |
| McKeown, B | 1 |
| Dimond, DG | 1 |
| Lam, JK | 1 |
| Wurster, L | 1 |
| Kiser, C | 1 |
| Driscoll, K | 1 |
| Razzante, M | 1 |
| Baraza, N | 1 |
| Lever, S | 1 |
| Dhukaram, V | 1 |
| Sauer, S | 1 |
| Goltz, JP | 1 |
| Gassenmaier, T | 1 |
| Kunz, AS | 1 |
| Bley, TA | 1 |
| Klein, D | 1 |
| Petritsch, B | 1 |
| Duncan, SM | 1 |
| Massicotte, MP | 1 |
| Ray, L | 1 |
| Kuhle, S | 1 |
| Bauman, ME | 1 |
| DeDea, L | 1 |
| Robb, DM | 1 |
| Kanji, Z | 1 |
| Kavanagh, D | 1 |
| Hill, AD | 1 |
| Martin, S | 1 |
| Power, C | 1 |
| McDermott, EW | 1 |
| O'Higgins, N | 1 |
| Murphy, K | 1 |
| Bleckner, LL | 1 |
| Buckenmaier, CC | 1 |
| Fazel, R | 1 |
| Froehlich, JB | 1 |
| Williams, DM | 1 |
| Saint, S | 1 |
| Nallamothu, BK | 1 |
| Kuzu, N | 1 |
| Ucar, H | 1 |
| Rathbun, SW | 1 |
| Aston, CE | 1 |
| Whitsett, TL | 1 |
| van Zuuren, EJ | 1 |
| Fedorowicz, Z | 1 |
| Qari, MH | 1 |
| Aljaouni, SK | 1 |
| Alardawi, MS | 1 |
| Fatani, H | 1 |
| Alsayes, FM | 1 |
| Zografos, P | 1 |
| Alsaigh, M | 1 |
| Alalfi, A | 1 |
| Alamin, M | 1 |
| Gadi, A | 1 |
| Mousa, SA | 1 |
| Stewart, AJ | 1 |
| Manson, LM | 1 |
| Dennis, R | 1 |
| Allan, PL | 1 |
| Ludlam, CA | 1 |
| Slesak, G | 1 |
| Döller, PC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Contention Alone Versus Anticoagulation for Symptomatic Calf Vein Thrombosis Diagnosed by Ultrasonography[NCT00421538] | Phase 3 | 260 participants (Actual) | Interventional | 2008-01-31 | Completed | ||
| The Effect of Three Different Local Cold Applications on Pain and Ecchymosis in Subcutaneous Heparin Injections[NCT04235244] | 54 participants (Actual) | Interventional | 2020-06-01 | Completed | |||
| Management of Superficial Thrombophlebitis[NCT00264381] | Phase 4 | 72 participants (Actual) | Interventional | 2002-10-31 | Completed | ||
| A Prospective, Randomized, Double-blind, Placebo Controlled, Multi-national Study of Therapeutic Anticoagulation Strategy for Acute Chest Syndrome in Adults[NCT02580773] | Phase 3 | 200 participants (Anticipated) | Interventional | 2016-12-16 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Change in pain at day 14 as measured by 11-point Box Pain Scale, 0 being the least amount of pain, and 10 the most amount of pain (NCT00264381)
Timeframe: Day 1, Day 14
| Intervention | units on a scale (Mean) |
|---|---|
| Ibuprofen 800 mg Tid | -2.28 |
| Dalteparin 200 U/kg Then 10,000 U Daily | -2.23 |
Number of participants with bleeding events related to treatment (NCT00264381)
Timeframe: 3 months
| Intervention | participants (Number) |
|---|---|
| Ibuprofen 800 mg Tid | 0 |
| Dalteparin 200 U/kg Then 10,000 U Daily | 0 |
Thrombosis progression and deep vein thrombosis at day 14 by ultrasound testing (NCT00264381)
Timeframe: Day 14
| Intervention | participants (Number) | |
|---|---|---|
| Thrombosis progression | VTE | |
| Dalteparin 200 U/kg Then 10,000 U Daily | 0 | 0 |
| Ibuprofen 800 mg Tid | 4 | 0 |
Symptomatic thrombosis extension (DVT) or pulmonary embolism at 3 months documented by radiologic testing. (NCT00264381)
Timeframe: 3 months
| Intervention | participants (Number) | |
|---|---|---|
| Thrombosis progression | VTE | |
| Dalteparin 200 U/kg Then 10,000 U Daily | 4 | 1 |
| Ibuprofen 800 mg Tid | 6 | 0 |
1 review available for dalteparin and Pain
| Article | Year |
|---|---|
Low-molecular-weight heparins for managing vasoocclusive crises in people with sickle cell disease: a summary of a cochrane systematic review.
Topics: Anemia, Sickle Cell; Female; Fibrinolytic Agents; Hemolysis; Heparin, Low-Molecular-Weight; Humans; | 2014 |
7 trials available for dalteparin and Pain
| Article | Year |
|---|---|
Effect of anticoagulant treatment on pain in distal deep vein thrombosis: an ancillary analysis from the cactus trial.
Topics: Anticoagulants; Canada; France; Humans; Nadroparin; Pain; Pain Measurement; Stockings, Compression; | 2019 |
A comparison of low-molecular-weight heparin and combined therapy of low-molecular-weight heparin with an anti-inflammatory agent in the treatment of superficial vein thrombosis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Drug Therapy, Combination; | 2009 |
Clinical evaluation of pain during subcutaneous injections of low molecular weight heparins in healthy volunteers.
Topics: Adult; Double-Blind Method; Enoxaparin; Humans; Injections, Subcutaneous; Male; Nadroparin; Pain; Pa | 1994 |
Comparison of two needle sizes for subcutaneous administration of enoxaparin: effects on size of hematomas and pain on injection.
Topics: Adult; Aged; Aged, 80 and over; Angina, Unstable; Anticoagulants; Enoxaparin; Female; Hematoma; Huma | 2002 |
The effect of cold on the occurrence of bruising, haematoma and pain at the injection site in subcutaneous low molecular weight heparin.
Topics: Anticoagulants; Clinical Nursing Research; Contusions; Cryotherapy; Enoxaparin; Female; Hematoma; Hu | 2001 |
A randomized trial of dalteparin compared with ibuprofen for the treatment of superficial thrombophlebitis.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dalte | 2012 |
Reduction of painful vaso-occlusive crisis of sickle cell anaemia by tinzaparin in a double-blind randomized trial.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Antisickling Agents; Double-Blind Method; Female; Fibrinolyt | 2007 |
12 other studies available for dalteparin and Pain
| Article | Year |
|---|---|
Spigelian hernia and pitfalls of postoperative anticoagulation.
Topics: Aged, 80 and over; Anticoagulants; Diagnosis, Differential; Enoxaparin; Fatal Outcome; Female; Hemat | 2017 |
No Fever, No Murmur, No Problem? A Concealed Case of Infective Endocarditis.
Topics: Adult; Amphetamine; Analgesics, Opioid; Anti-Bacterial Agents; C-Reactive Protein; Endocarditis; Eno | 2019 |
The Solitary Blue Toe: A Unique Presentation of Antiphospholipid Syndrome.
Topics: Antibodies, Antiphospholipid; Anticoagulants; Antiphospholipid Syndrome; Blue Toe Syndrome; Computed | 2019 |
Home therapy pathway - safe and streamlined method of initial management of ankle fractures.
Topics: Adult; Aged; Aged, 80 and over; Ankle Injuries; Anticoagulants; Case-Control Studies; Casts, Surgica | 2013 |
Partial segmental thrombosis of the corpus cavernosum (PSTCC) diagnosed by contrast-enhanced ultrasound: a case report.
Topics: Adult; Anticoagulants; Aspirin; Contrast Media; Edema; Enoxaparin; Humans; Male; Pain; Penile Diseas | 2014 |
Topical lidocaine and the effect on enoxaparin absorption in children: a pilot study.
Topics: Absorption; Administration, Topical; Anesthetics, Local; Child; Child, Preschool; Clinical Protocols | 2010 |
Tapentadol for pain; enoxaparin after prosthetic valve replacement.
Topics: Anticoagulants; Enoxaparin; Heart Valve Prosthesis Implantation; Humans; Pain; Phenols; Tapentadol; | 2011 |
Life threatening haemorrhagic events associated with the administration of low-molecular-weight-heparin.
Topics: Adult; Aged; Aged, 80 and over; Critical Illness; Enoxaparin; Female; Hemorrhage; Heparin, Low-Molec | 2004 |
Continuous peripheral nerve catheters in patients receiving low molecular weight heparin.
Topics: Anticoagulants; Catheters, Indwelling; Device Removal; Drug Administration Schedule; Enoxaparin; Fem | 2007 |
Clinical problem-solving. A sinister development--a 35-year-old woman presented to the emergency department with a 2-day history of progressive swelling and pain in her left leg, without antecedent trauma.
Topics: Adult; Anticoagulants; Constriction, Pathologic; Contraceptives, Oral; Edema; Enoxaparin; Female; Fi | 2007 |
Thrombosis in a duplicated superficial femoral vein in a patient with haemophilia A.
Topics: Adult; Factor VIII; Femoral Vein; Fibrinolytic Agents; Hemophilia A; Heparin, Low-Molecular-Weight; | 2000 |
[Fever and calf tenderness after travel in Thailand: murine typhus and deep vein thrombosis].
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Dehydration; Fever; Fibrinolytic Agents; Germany; Hepar | 2001 |