Page last updated: 2024-10-18

dalteparin and Necrosis

dalteparin has been researched along with Necrosis in 34 studies

Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"Although congenital afibrinogenemia is a rare autosomal recessive bleeding disorder, it can be more frequently encountered in countries where consanguineous marriages are common."7.81A case of congenital afibrinogenemia complicated with thromboembolic events that required repeated amputations. ( Işik, B; Karakukcu, M; Mutlu, FT; Ozdemir, MA; Patiroglu, T; Unal, E; Yilmaz, E, 2015)
"Warfarin-induced skin necrosis is a rare complication associated with the use of oral anticoagulants."7.72A case of warfarin skin necrosis despite enoxaparin anticoagulation in a patient with protein S deficiency. ( Alexander, JB; Ierardi, R; Tai, CY, 2004)
"An uncommon case of delayed-onset dalteparin-induced skin necrosis in an 83-year-old Caucasian female patient associated with heparin-induced thrombocytopaenia (HIT) presenting on day 30 following dalteparin therapy is reported."3.85Delayed-onset heparin-induced skin necrosis: a rare complication of perioperative heparin therapy. ( Gan, WK, 2017)
"Although congenital afibrinogenemia is a rare autosomal recessive bleeding disorder, it can be more frequently encountered in countries where consanguineous marriages are common."3.81A case of congenital afibrinogenemia complicated with thromboembolic events that required repeated amputations. ( Işik, B; Karakukcu, M; Mutlu, FT; Ozdemir, MA; Patiroglu, T; Unal, E; Yilmaz, E, 2015)
"Histopathological examination of the enoxaparin and rivaroxaban groups revealed that the skin was mostly normal or intact with minimal inflammation."3.80Effects of enoxaparin and rivaroxaban on tissue survival in skin degloving injury: an experimental study. ( Alabalik, U; Alemdar, C; Azboy, I; Bulut, M; Demirtaş, A; Uçar, Y, 2014)
" Coumarin-induced skin necrosis was a recurrent feature during oral anticoagulation therapy, forcing her physicians to treat her with nadroparin (Fraxiparin) for only a few months."3.72Late onset of clinical symptoms and recurrent ecchymotic skin lesions in a 12-year-old girl with a severe double heterozygous protein C deficiency. ( Alhenc-Gelas, M; Corazza, F; Demulder, A; Ferster, A; Loop, M, 2004)
"Warfarin-induced skin necrosis is a rare complication associated with the use of oral anticoagulants."3.72A case of warfarin skin necrosis despite enoxaparin anticoagulation in a patient with protein S deficiency. ( Alexander, JB; Ierardi, R; Tai, CY, 2004)
" The relationship between warfarin induced skin necrosis and level of anticoagulation was investigated."3.70Homozygous protein C deficiency: description of a new mutation and successful treatment with low molecular weight heparin. ( Andrew, M; Halton, J; Jardine, L; Johnston, M; Marlar, R; Massicotte, MP; Monagle, P; Vegh, P; Webber, C, 1998)
"Skin necrosis is a rare complication in intensive care unit."1.34[Nadroparin-induced skin necrosis then thrombocytosis in intensive care unit: difficulty in diagnosis]. ( Denninger, MH; Mantz, J; Paugam-Burtz, C; Perbet, S; Trouiller, P, 2007)
"Heparin necrosis is characterised by widespread life-threatening cutaneous necrosis and systemic thrombosis, in which fatal progression of disease can only be halted by stopping heparin therapy."1.33Generalised cutaneous necrosis: a complication of low-molecular-weight heparin. ( Knight, AG; Patel, GK, 2005)
"A 43-year-old white woman with adult respiratory distress syndrome developed localized dermal necrosis and thrombocytopenia secondary to subcutaneous administration of unfractionated heparin."1.30Enoxaparin-associated dermal necrosis: a consequence of cross-reactivity with heparin-mediated antibodies. ( Kollef, MH; Schaiff, RA; Tonn, ME, 1997)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (11.76)18.2507
2000's14 (41.18)29.6817
2010's14 (41.18)24.3611
2020's2 (5.88)2.80

Authors

AuthorsStudies
Pérez, DL1
Peña-Romero, AG1
Díaz-González, JM1
Domínguez-Cherit, J1
Askar, I1
Erbas, MK1
Gurlek, A1
Loop, M1
Ferster, A1
Corazza, F1
Alhenc-Gelas, M1
Demulder, A1
Perbet, S1
Trouiller, P1
Paugam-Burtz, C1
Denninger, MH1
Mantz, J1
Pasha, AK1
McBane Ii, RD1
Byrne, EM1
Khattab, A1
Chen, F1
Bhagavatula, R1
Li, J1
Inwald, G1
Thomas, M1
Gucalp, A1
Parameswaran, R1
Lacouture, M1
Abou-Alfa, G1
Soff, G1
Azboy, I1
Demirtaş, A1
Bulut, M1
Alabalik, U1
Uçar, Y1
Alemdar, C1
Senel, S1
Zorlu, P1
Dogan, B1
Acar, M1
Ozdemir, MA1
Işik, B1
Patiroglu, T1
Karakukcu, M1
Mutlu, FT1
Yilmaz, E1
Unal, E1
Schleich, C1
Hansen, TJ1
Kirby, JS1
Neloska, L1
Damevska, K1
Pavleska, L1
Vargas-Hitos, JA1
Sabio, JM1
Navarrete-Navarrete, N1
Zamora-Pasadas, M1
Jiménez-Alonso, J1
Olah, Z1
Bereczky, Z1
Szarvas, M1
Boda, Z1
Karmegam, A1
Desai, A1
Peter, V1
Raut, V1
Yurttutan, S1
Ozdemir, R1
Erdeve, O1
Calisici, E1
Oncel, MY1
Oguz, SS1
Dilmen, U1
Yazbek, MA1
Velho, P1
Nadruz, W1
Mahayri, N1
Appenzeller, S1
Costallat, LT1
Miguélez, A1
Barrientos, N1
López-Ríos, F1
Vanaclocha, F1
Iglesias, L1
Scharf, Y1
Hershkoviz, R1
Tai, CY1
Ierardi, R1
Alexander, JB1
Toll, A1
Gallardo, F1
Abella, ME1
Fontcuberta, J1
Barranco, C1
Pujol, RM1
Nadir, Y1
Mazor, Y1
Reuven, B1
Sarig, G1
Brenner, B1
Krivoy, N1
Criado, PR1
Bernardelli, IM1
Rivitti, EA1
Sotto, MN1
Vilella, MA1
Valente, NY1
Martins, JE1
Daniels, AH1
Wilson, CL1
Harrison, RA1
Fried, M1
Kahanovich, S1
Dagan, R1
Tonn, ME1
Schaiff, RA1
Kollef, MH1
Monagle, P1
Andrew, M1
Halton, J1
Marlar, R1
Jardine, L1
Vegh, P1
Johnston, M1
Webber, C1
Massicotte, MP1
Lefebvre, I1
Delaporte, E1
Dejobert, Y1
Catteau, B1
Piette, F1
Bergoend, H1
Gan, WK1
Peitsch, WK1
Glorer, E1
Dempfle, CE1
Back, W1
Bayerl, C1
Goerdt, S1
Moore, A1
Lau, E1
Yang, C1
Mackool, B1
Kuter, DJ1
Roth, B1
Debarbieux, S1
Causeret, AS1
Trzeciak, MC1
Claudy, A1
Patel, GK1
Knight, AG1

Other Studies

34 other studies available for dalteparin and Necrosis

ArticleYear
Nadroparin-induced skin necrosis: clinical manifestation of HIT-2 even in the absence of thrombocytopaenia.
    BMJ case reports, 2016, Apr-26, Volume: 2016

    Topics: Adult; Humans; Male; Nadroparin; Necrosis; Skin Diseases; Thrombocytopenia

2016
Effects of heparin fractions on the prevention of skin necrosis resulting from adriamycin extravasation: an experimental study.
    Annals of plastic surgery, 2002, Volume: 49, Issue:3

    Topics: Animals; Antineoplastic Agents; Dalteparin; Doxorubicin; Extravasation of Diagnostic and Therapeutic

2002
Late onset of clinical symptoms and recurrent ecchymotic skin lesions in a 12-year-old girl with a severe double heterozygous protein C deficiency.
    Journal of pediatric hematology/oncology, 2004, Volume: 26, Issue:1

    Topics: Age of Onset; Anticoagulants; Child; Coumarins; DNA Mutational Analysis; Ecchymosis; Family Health;

2004
[Nadroparin-induced skin necrosis then thrombocytosis in intensive care unit: difficulty in diagnosis].
    Annales francaises d'anesthesie et de reanimation, 2007, Volume: 26, Issue:9

    Topics: Adult; Anticoagulants; Humans; Intensive Care Units; Male; Nadroparin; Necrosis; Skin; Thrombocytosi

2007
Heparin Skin Necrosis in Heparin-Induced Thrombocytopenia.
    Mayo Clinic proceedings, 2021, Volume: 96, Issue:9

    Topics: Aged; Anticoagulants; Enoxaparin; Female; Humans; Injections; Necrosis; Skin Diseases; Thrombocytope

2021
Rare presentation of enoxaparin-induced skin necrosis in a postoperative patient.
    BMJ case reports, 2022, Apr-13, Volume: 15, Issue:4

    Topics: Anticoagulants; Enoxaparin; Female; Heparin; Heparin, Low-Molecular-Weight; Humans; Necrosis; Postop

2022
A Rare Case of Enoxaparin-Induced Skin Necrosis Without Thrombocytopenia.
    American journal of physical medicine & rehabilitation, 2019, Volume: 98, Issue:5

    Topics: Abdomen; Adult; Anticoagulants; Drug Eruptions; Enoxaparin; Female; Humans; Necrosis; Skin Diseases

2019
Skin necrosis induced by generic enoxaparin.
    American journal of hematology, 2013, Volume: 88, Issue:4

    Topics: Aged; Anticoagulants; Drugs, Generic; Enoxaparin; Female; Humans; Male; Middle Aged; Necrosis; Skin;

2013
Effects of enoxaparin and rivaroxaban on tissue survival in skin degloving injury: an experimental study.
    Acta orthopaedica et traumatologica turcica, 2014, Volume: 48, Issue:2

    Topics: Animals; Disease Models, Animal; Enoxaparin; Fibrinolytic Agents; Inflammation; Male; Morpholines; N

2014
Successfully treated fingertip necrosis in an infant with primary Raynaud phenomenon.
    Indian journal of pediatrics, 2014, Volume: 81, Issue:12

    Topics: Anticoagulants; Drug Therapy, Combination; Enoxaparin; Fingers; Humans; Infant; Male; Necrosis; Nife

2014
A case of congenital afibrinogenemia complicated with thromboembolic events that required repeated amputations.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2015, Volume: 26, Issue:3

    Topics: Afibrinogenemia; Amputation, Surgical; Anemia; Anticoagulants; Blood Coagulation Tests; Disease Prog

2015
JAAD grand rounds quiz. Dusky bullae on the abdomen.
    Journal of the American Academy of Dermatology, 2014, Volume: 71, Issue:5

    Topics: Abdominal Wall; Anticoagulants; Blister; Drug Eruptions; Enoxaparin; Female; Humans; Middle Aged; Ne

2014
Enoxaparin-induced Skin Necrosis.
    Acta dermatovenerologica Croatica : ADC, 2015, Volume: 23, Issue:3

    Topics: Aged; Anticoagulants; Comorbidity; Diagnosis, Differential; Enoxaparin; Fatal Outcome; Female; Human

2015
Severe digital necrosis as the clinical onset of antiphospholipid syndrome.
    Internal and emergency medicine, 2016, Volume: 11, Issue:5

    Topics: Aged; Antiphospholipid Syndrome; Enoxaparin; Fibrinolytic Agents; Humans; Male; Necrosis

2016
Coagulation: cascade!
    Lancet (London, England), 2011, Aug-20, Volume: 378, Issue:9792

    Topics: Aged; Anticoagulants; Coumarins; Enoxaparin; Gangrene; Heparin; Humans; International Normalized Rat

2011
Tissue necrosis after use of enoxaparin in total knee arthroplasty: a case report.
    American journal of orthopedics (Belle Mead, N.J.), 2011, Volume: 40, Issue:8

    Topics: Anticoagulants; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Debridement; Enoxaparin; Fem

2011
Intrauterine upper extremity thrombosis successfully treated with recombinant tissue plasminogen activator, enoxaparin and collagenase.
    Acta haematologica, 2012, Volume: 127, Issue:3

    Topics: Collagenases; Enoxaparin; Fetal Diseases; Fibrinolytic Agents; Humans; Infant, Newborn; Male; Necros

2012
Extensive skin necrosis induced by low-molecular-weight heparin in a patient with systemic lupus erythematosus and antiphospholipid syndrome.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2012, Volume: 18, Issue:4

    Topics: Antiphospholipid Syndrome; Aspirin; Drug Eruptions; Drug Therapy, Combination; Enoxaparin; Female; F

2012
Necrotic livedo reticularis, multiple cholesterol emboli and ANCA.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2003, Volume: 17, Issue:3

    Topics: Abdomen; Aged; Buttocks; Diagnosis, Differential; Embolism, Cholesterol; Enoxaparin; Humans; Hyperch

2003
[Enoxaparin induced skin necrosis].
    Harefuah, 2003, Volume: 142, Issue:11

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Enoxaparin; Female; Humans; Necrosis; Skin; Skin Diseases

2003
A case of warfarin skin necrosis despite enoxaparin anticoagulation in a patient with protein S deficiency.
    Annals of vascular surgery, 2004, Volume: 18, Issue:2

    Topics: Anticoagulants; Arterial Occlusive Diseases; Enoxaparin; Female; Fibrinolytic Agents; Heparin, Low-M

2004
Low-molecular-weight heparin-induced skin necrosis: a potential association with pre-existent hypercoagulable states.
    International journal of dermatology, 2005, Volume: 44, Issue:11

    Topics: Aged; Biopsy, Needle; Dose-Response Relationship, Drug; Drug Administration Schedule; Enoxaparin; Fo

2005
A fatal case of enoxaparin induced skin necrosis and thrombophilia.
    European journal of haematology, 2006, Volume: 77, Issue:2

    Topics: Aged; Anticoagulants; Diagnosis, Differential; Drug Eruptions; Enoxaparin; Factor V; Factor VIII; Fa

2006
Childhood-onset skin necrosis resulting from protein C deficiency.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2007, Volume: 21, Issue:4

    Topics: Blood Component Transfusion; Child, Preschool; Enoxaparin; Fibrinolytic Agents; Follow-Up Studies; H

2007
Hepatitis C-associated leukocytoclastic vasculitis with anticardiolipin antibodies causing penile necrosis and deep venous thrombosis in the absence of cryoglobulinemia.
    Journal of hospital medicine, 2008, Volume: 3, Issue:2

    Topics: Antibodies, Anticardiolipin; Anticoagulants; Cryoglobulinemia; Debridement; Enoxaparin; Hepatitis C;

2008
Enoxaparin-induced skin necrosis.
    Annals of internal medicine, 1996, Sep-15, Volume: 125, Issue:6

    Topics: Adult; Anticoagulants; Enoxaparin; Female; Humans; Middle Aged; Necrosis; Skin

1996
Enoxaparin-associated dermal necrosis: a consequence of cross-reactivity with heparin-mediated antibodies.
    The Annals of pharmacotherapy, 1997, Volume: 31, Issue:3

    Topics: Adult; Antibodies; Anticoagulants; Cross Reactions; Drug Eruptions; Enoxaparin; Female; Heparin; Hum

1997
Homozygous protein C deficiency: description of a new mutation and successful treatment with low molecular weight heparin.
    Thrombosis and haemostasis, 1998, Volume: 79, Issue:4

    Topics: Adult; Anticoagulants; Biomarkers; Bone Density; Child; Drug Eruptions; Enoxaparin; Female; Heparin;

1998
[Enoxaparin-induced cutaneous necrosis localized on insulin lipodystrophies].
    Annales de dermatologie et de venereologie, 1997, Volume: 124, Issue:5

    Topics: Anticoagulants; Enoxaparin; Female; Humans; Injections, Subcutaneous; Insulin; Lipodystrophy; Middle

1997
Delayed-onset heparin-induced skin necrosis: a rare complication of perioperative heparin therapy.
    BMJ case reports, 2017, Nov-03, Volume: 2017

    Topics: Aged, 80 and over; Anticoagulants; Arthroplasty, Replacement, Hip; Dalteparin; Diagnosis, Differenti

2017
[Cutaneous necroses mainly on the extremities].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2004, Volume: 55, Issue:4

    Topics: Aged; Aged, 80 and over; Anticoagulants; Dalteparin; Diagnosis, Differential; Extremities; Female; F

2004
Dalteparin-induced skin necrosis in a patient with metastatic lung adenocarcinoma.
    American journal of clinical oncology, 2007, Volume: 30, Issue:3

    Topics: Adenocarcinoma; Anticoagulants; Dalteparin; Female; Humans; Liver Neoplasms; Lung Neoplasms; Middle

2007
[A necrotic plaque on the thigh].
    Annales de dermatologie et de venereologie, 2003, Volume: 130, Issue:11

    Topics: Adult; Anticoagulants; Drug Eruptions; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Humans; M

2003
Generalised cutaneous necrosis: a complication of low-molecular-weight heparin.
    International wound journal, 2005, Volume: 2, Issue:3

    Topics: Aged; Female; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Humans; Necrosis; Skin; Tinzaparin

2005