Page last updated: 2024-10-18

dalteparin and Injury, Ischemia-Reperfusion

dalteparin has been researched along with Injury, Ischemia-Reperfusion in 14 studies

Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)

Research Excerpts

ExcerptRelevanceReference
"Since low molecular weight heparin has greater bioavailability and sustained serum levels in vivo than unfractionated heparin, it has been used to supplant unfractionated heparin to achieve therapeutic anticoagulation in humans."1.35Enoxaparin does not ameliorate limb ischemia-reperfusion injury. ( Abbruzzese, TA; Albadawi, H; Kang, J; Lamuraglia, GM; Patel, VI; Watkins, MT; Yoo, JH, 2008)
"Pretreatment with indomethacin completely reversed both of the therapeutic effects of dalteparin, whereas pretreatment with NS-398, a selective inhibitor of cyclooxygenase-2, did not."1.33Dalteparin, a low molecular weight heparin, attenuates inflammatory responses and reduces ischemia-reperfusion-induced liver injury in rats. ( Harada, N; Okajima, K; Uchiba, M, 2006)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (42.86)29.6817
2010's5 (35.71)24.3611
2020's3 (21.43)2.80

Authors

AuthorsStudies
Yan, X1
Liang, J1
Li, X1
Hu, Z1
Chen, J1
Zheng, J1
Li, R1
Demirtas, S1
Karahan, O1
Yazıcı, S1
Guclu, O1
Calıskan, A1
Tezcan, O1
Kaplan, I1
Yavuz, C1
Dogan Ozcil, M1
Ozcan, O1
Hakverdi, S1
Bayraktar, HS1
Dirican, E1
Kacmaz, F1
Bostancı, MS1
Budak, O1
Çakiroğlu, H1
Köse, O1
Durmaz, Ö1
Cokluk, E1
Fındık, O1
Yılmaz, MY1
Yazır, Y1
Rençber, SF1
Sarıhan, KK1
Kunt, AT1
Kaya, C1
Turgut, H1
Cengiz, H1
Turan, A1
Ekin, M1
Yaşar, L1
Cavusoglu, T1
Ozcan, N1
Ogus, E1
Ozcan, A1
Kaymak, C1
Sahin, S1
Yilmaz, FM1
Tezel, S1
Walensi, M1
de Groot, H1
Schulz, R1
Hartmann, M1
Petrat, F1
Uzan, A1
Welsh, RC1
Armstrong, PW1
Abbruzzese, TA1
Albadawi, H1
Kang, J1
Patel, VI1
Yoo, JH1
Lamuraglia, GM1
Watkins, MT1
Gottmann, U1
Mueller-Falcke, A1
Schnuelle, P1
Birck, R1
Nickeleit, V1
van der Woude, FJ1
Yard, BA1
Braun, C1
Harada, N1
Okajima, K1
Uchiba, M1
Menger, MD1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Influence of Ovarian Torsion and Surgical De-torsion on Ovarian Reserve[NCT03852615]100 participants (Anticipated)Interventional2019-03-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for dalteparin and Injury, Ischemia-Reperfusion

ArticleYear
[Thrombosis and ischemia: experimental data].
    Archives des maladies du coeur et des vaisseaux, 2002, Volume: 95 Spec No 7

    Topics: Animals; Apoptosis; Coronary Thrombosis; Disease Models, Animal; Dogs; Enoxaparin; Fibrinolytic Agen

2002
A marriage of enhancement: fibrinolysis and conjunctive therapy.
    Thrombosis and haemostasis, 2004, Volume: 92, Issue:6

    Topics: Animals; Antithrombins; Aspirin; Blood Platelets; Cell Adhesion; Clinical Trials as Topic; Dose-Resp

2004

Trials

2 trials available for dalteparin and Injury, Ischemia-Reperfusion

ArticleYear
Enoxaparin effect on malondialdehyde levels in laparoscopic cholecystectomy.
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2011, Volume: 24, Issue:5

    Topics: Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Cholecystectomy, Laparoscopic; Enoxa

2011
Influence of hypersulfated and low molecular weight heparins on ischemia/reperfusion: injury and allograft rejection in rat kidneys.
    Transplant international : official journal of the European Society for Organ Transplantation, 2007, Volume: 20, Issue:6

    Topics: Albuminuria; Animals; Anticoagulants; Graft Rejection; Heparin; Heparin, Low-Molecular-Weight; Human

2007

Other Studies

10 other studies available for dalteparin and Injury, Ischemia-Reperfusion

ArticleYear
Identify Key Genes Correlated to Ischemia-Reperfusion Injury in Aging Livers.
    Disease markers, 2023, Volume: 2023

    Topics: Aging; Animals; ARNTL Transcription Factors; Humans; Immediate-Early Proteins; Liver; Mice; Nadropar

2023
Investigation of possible prophylactic, renoprotective, and cardioprotective effects of thromboprophylactic drugs against ischemia-reperfusion injury.
    The Kaohsiung journal of medical sciences, 2015, Volume: 31, Issue:3

    Topics: Animals; Anticoagulants; Aryldialkylphosphatase; Aspirin; Cardiotonic Agents; Clopidogrel; Dipeptida

2015
Impact of Enoxaparin +α Lipoic acid combination on oxidative stress, follicle development and apoptotic damage in ovarian ischemia reperfusion model.
    European review for medical and pharmacological sciences, 2022, Volume: 26, Issue:18

    Topics: Animals; Antioxidants; Biomarkers; Catalase; Enoxaparin; Female; Follicle Stimulating Hormone; Gluta

2022
Effect of protection of enoxaparin against experimental ischemia/reperfusion injury in the rat ovary on in vitro fertilization outcomes.
    Revista da Associacao Medica Brasileira (1992), 2023, Volume: 69, Issue:3

    Topics: Animals; Anti-Mullerian Hormone; Antioxidants; Enoxaparin; Female; Fertilization in Vitro; Humans; I

2023
Investigation of the protective effect of enoxaparin and ticagrelor pretreatment against ischemia-reperfusion injury in rat lung tissue.
    Revista da Associacao Medica Brasileira (1992), 2019, Volume: 65, Issue:9

    Topics: Animals; Aorta, Abdominal; Apoptosis; Caspase 3; Disease Models, Animal; Enoxaparin; Lung; Lung Inju

2019
Effect of detorsion alone and in combination with enoxaparin therapy on ovarian reserve and serum antimüllerian hormone levels in a rat ovarian torsion model.
    Fertility and sterility, 2014, Volume: 102, Issue:3

    Topics: Animals; Anti-Mullerian Hormone; Cell Count; Combined Modality Therapy; Disease Models, Animal; Enox

2014
Mesenteric ischemia-reperfusion injury: clearly improved hemodynamics but only minor protection of the rat small intestine by (sub)therapeutic heparin sodium and enoxaparin doses.
    The Journal of surgical research, 2013, Volume: 179, Issue:1

    Topics: Animals; Anticoagulants; Blood Pressure; Dose-Response Relationship, Drug; Enoxaparin; Heart Rate; H

2013
Enoxaparin does not ameliorate limb ischemia-reperfusion injury.
    The Journal of surgical research, 2008, Jun-15, Volume: 147, Issue:2

    Topics: Animals; Anticoagulants; Biomarkers; Enoxaparin; Hindlimb; Inflammation; Male; Mice; Mice, Inbred C5

2008
Dalteparin, a low molecular weight heparin, attenuates inflammatory responses and reduces ischemia-reperfusion-induced liver injury in rats.
    Critical care medicine, 2006, Volume: 34, Issue:7

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anticoagulants; Calcium; Cyclooxygenase 2 Inhibitors; Daltepa

2006
Dalteparin: only protective in hepatic ischemia-reperfusion or also capable of preventing injury in liver hyperperfusion syndrome?
    Critical care medicine, 2006, Volume: 34, Issue:7

    Topics: Animals; Anticoagulants; Dalteparin; Fibrinolytic Agents; Liver; Liver Diseases; Rats; Reperfusion I

2006