dalteparin has been researched along with Injuries, Spinal Cord in 20 studies
Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Similar compliance, health status, deep venous thrombosis, and bleeding rates were found between dalteparin and enoxaparin." | 9.10 | Comparison of dalteparin and enoxaparin for deep venous thrombosis prophylaxis in patients with spinal cord injury. ( Chan, KT; Chiou-Tan, FY; Donovan, WH; Garza, H; Graves, DE; Holmes, SA; Parsons, KC; Rintala, DH; Robertson, CS, 2003) |
| "Paraplegia (as opposed to tetraplegia) was the only risk factor identified for VTE." | 5.35 | Dalteparin vs low-dose unfractionated heparin for prophylaxis against clinically evident venous thromboembolism in acute traumatic spinal cord injury: a retrospective cohort study. ( Anderson, D; Douglas, JA; Pike, J; Short, C; Thompson, K; Worley, S, 2008) |
| "Similar compliance, health status, deep venous thrombosis, and bleeding rates were found between dalteparin and enoxaparin." | 5.10 | Comparison of dalteparin and enoxaparin for deep venous thrombosis prophylaxis in patients with spinal cord injury. ( Chan, KT; Chiou-Tan, FY; Donovan, WH; Garza, H; Graves, DE; Holmes, SA; Parsons, KC; Rintala, DH; Robertson, CS, 2003) |
| "The risk of venous thromboembolism is high after spinal cord injury (SCI)." | 2.71 | Prevention of venous thromboembolism in the acute treatment phase after spinal cord injury: a randomized, multicenter trial comparing low-dose heparin plus intermittent pneumatic compression with enoxaparin. ( , 2003) |
| " Multiple drugs and dosing regimens have been suggested for pharmacoprophylaxis." | 1.36 | Gold Medal Forum Winner. Unfractionated heparin three times a day versus enoxaparin in the prevention of deep vein thrombosis in trauma patients. ( Arnold, JD; Barker, DE; Burkholder, HC; Dart, BW; Longley, JM; Maxwell, RA; Mejia, VA; Smith, PW, 2010) |
| "Paraplegia (as opposed to tetraplegia) was the only risk factor identified for VTE." | 1.35 | Dalteparin vs low-dose unfractionated heparin for prophylaxis against clinically evident venous thromboembolism in acute traumatic spinal cord injury: a retrospective cohort study. ( Anderson, D; Douglas, JA; Pike, J; Short, C; Thompson, K; Worley, S, 2008) |
| "Clinically symptomatic proximal deep vein thrombosis (DVT) or pulmonary embolism (PE) rates were 1." | 1.34 | Dalteparin versus enoxaparin for venous thromboembolism prophylaxis in acute spinal cord injury and major orthopedic trauma patients: 'DETECT' trial. ( Chan, E; Chittock, D; de Lemos, J; Gorman, SK; Ho, SG; Simons, RK; Slavik, RS; Wing, PC, 2007) |
| " However, emerging evidence suggests that different dosing strategies may be equivalent." | 1.32 | Daily vs twice daily enoxaparin in the prevention of venous thromboembolic disorders during rehabilitation following acute spinal cord injury. ( Chen, D; Crandall, S; Hebbeler, SL; Marciniak, CM; Mendelewski, S; Nussbaum, S, 2004) |
| "Enoxaparin and MPA can be used in the treatment of spinal cord injuries." | 1.31 | Medroxyprogesterone acetate, enoxaparin and pentoxyfylline cause alterations in lipid peroxidation, paraoxonase (PON1) activities and homocysteine levels in the acute oxidative stress in an experimental model of spinal cord injury. ( Akdemir, I; Erol, FS; Gursu, F; Kaplan, M; Kilic, N; Tiftikci, M; Topsakal, C, 2002) |
| "Patients with clinical suspicion of deep venous thrombosis or pulmonary embolism were investigated as appropriate." | 1.31 | Prophylaxis of thromboembolism in spinal injuries--results of enoxaparin used in 276 patients. ( Deep, K; Fraser, MH; Jigajinni, MV; McLean, AN, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 11 (55.00) | 29.6817 |
| 2010's | 6 (30.00) | 24.3611 |
| 2020's | 2 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Godat, LN | 1 |
| Haut, ER | 1 |
| Moore, EE | 1 |
| Knudson, MM | 1 |
| Costantini, TW | 1 |
| Ito, S | 1 |
| Ozaki, T | 1 |
| Morozumi, M | 1 |
| Imagama, S | 1 |
| Kadomatsu, K | 1 |
| Sakamoto, K | 1 |
| de Almeida, RL | 2 |
| Rodrigues, CC | 1 |
| Melo E Silva, CA | 1 |
| Beraldo, PSS | 2 |
| Amado, VM | 2 |
| Gonzaga, BPM | 1 |
| Yeung, V | 1 |
| Formal, C | 1 |
| Lau, E | 1 |
| Margolis, RU | 1 |
| Arnold, JD | 1 |
| Dart, BW | 1 |
| Barker, DE | 1 |
| Maxwell, RA | 1 |
| Burkholder, HC | 1 |
| Mejia, VA | 1 |
| Smith, PW | 1 |
| Longley, JM | 1 |
| Marciniak, CM | 2 |
| Kaplan, J | 1 |
| Welty, L | 1 |
| Chen, D | 2 |
| Thumbikat, P | 1 |
| Poonnoose, PM | 1 |
| Balasubrahmaniam, P | 1 |
| Ravichandran, G | 1 |
| McClelland, MR | 1 |
| Topsakal, C | 1 |
| Kilic, N | 1 |
| Erol, FS | 1 |
| Kaplan, M | 1 |
| Akdemir, I | 1 |
| Tiftikci, M | 1 |
| Gursu, F | 1 |
| Chiou-Tan, FY | 1 |
| Garza, H | 1 |
| Chan, KT | 1 |
| Parsons, KC | 1 |
| Donovan, WH | 1 |
| Robertson, CS | 1 |
| Holmes, SA | 1 |
| Graves, DE | 1 |
| Rintala, DH | 1 |
| Hebbeler, SL | 1 |
| Crandall, S | 1 |
| Nussbaum, S | 1 |
| Mendelewski, S | 1 |
| Slavik, RS | 1 |
| Chan, E | 1 |
| Gorman, SK | 1 |
| de Lemos, J | 1 |
| Chittock, D | 1 |
| Simons, RK | 1 |
| Wing, PC | 1 |
| Ho, SG | 1 |
| Tomaio, A | 1 |
| Kirshblum, SC | 1 |
| O'Connor, KC | 1 |
| Johnston, M | 1 |
| Deep, K | 1 |
| Jigajinni, MV | 1 |
| McLean, AN | 1 |
| Fraser, MH | 1 |
| Wade, WE | 1 |
| Spruill, WJ | 1 |
| Vanderbeke, I | 1 |
| Boll, D | 1 |
| Verguts, JK | 1 |
| Worley, S | 1 |
| Short, C | 1 |
| Pike, J | 1 |
| Anderson, D | 1 |
| Douglas, JA | 1 |
| Thompson, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Different Approach to Preventing Thrombosis (ADAPT): A Randomized Controlled Trial Comparing Low Molecular Weight Heparin to Acetylsalicylic Acid in Orthopedic Trauma Patients[NCT02774265] | Phase 3 | 329 participants (Actual) | Interventional | 2016-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
DVT and how the diagnosis was made will be recorded. The number of events in participants in each arm will be compared to evaluate efficacy. (NCT02774265)
Timeframe: 90 days
| Intervention | Participants (Count of Participants) |
|---|---|
| VTE Prophylaxis With Enoxaparin 30mg BID | 5 |
| VTE Prophylaxis With Aspirin 81mg BID | 9 |
Bases on imaging obtained for symptoms. (NCT02774265)
Timeframe: 90 days
| Intervention | Participants (Count of Participants) |
|---|---|
| VTE Prophylaxis With Enoxaparin 30mg BID | 6 |
| VTE Prophylaxis With Aspirin 81mg BID | 2 |
Includes a greater than 2g/dL drop in hemoglobin, blood transfusion, hematoma evacuation, re-operation for a deep surgical site infection or minor procedure for bleeding and GI bleed (NCT02774265)
Timeframe: 90 days
| Intervention | Participants (Count of Participants) |
|---|---|
| VTE Prophylaxis With Enoxaparin 30mg BID | 52 |
| VTE Prophylaxis With Aspirin 81mg BID | 53 |
3 trials available for dalteparin and Injuries, Spinal Cord
| Article | Year |
|---|---|
Prevention of venous thromboembolism in the rehabilitation phase after spinal cord injury: prophylaxis with low-dose heparin or enoxaparin.
Topics: Adult; Anticoagulants; Enoxaparin; Female; Hemorrhage; Heparin; Humans; Male; Prospective Studies; R | 2003 |
Prevention of venous thromboembolism in the acute treatment phase after spinal cord injury: a randomized, multicenter trial comparing low-dose heparin plus intermittent pneumatic compression with enoxaparin.
Topics: Acute Disease; Adult; Anticoagulants; Bandages; Combined Modality Therapy; Enoxaparin; Female; Hemor | 2003 |
Comparison of dalteparin and enoxaparin for deep venous thrombosis prophylaxis in patients with spinal cord injury.
Topics: Adolescent; Adult; Aged; Dalteparin; Enoxaparin; Female; Fibrinolytic Agents; Health Status Indicato | 2003 |
17 other studies available for dalteparin and Injuries, Spinal Cord
| Article | Year |
|---|---|
Venous thromboembolism risk after spinal cord injury: A secondary analysis of the CLOTT study.
Topics: Anticoagulants; Enoxaparin; Female; Heparin; Humans; Male; Prospective Studies; Pulmonary Embolism; | 2023 |
Enoxaparin promotes functional recovery after spinal cord injury by antagonizing PTPRĪ.
Topics: Animals; Anticoagulants; Enoxaparin; Evoked Potentials, Motor; Female; HEK293 Cells; Humans; Rats; R | 2021 |
Comparison of two pharmacological prophylaxis strategies for venous thromboembolism in spinal cord injury patients: a retrospective study.
Topics: Adult; Anticoagulants; Brazil; Enoxaparin; Female; Humans; Incidence; Male; Retrospective Studies; R | 2019 |
Case report - Gluteal hematoma in two spinal cord patients on enoxaparin for venous thromboembolism prophylaxis: evidence needed for a wiser choice.
Topics: Adult; Anticoagulants; Buttocks; Enoxaparin; Hematoma; Humans; Male; Spinal Cord Injuries; Venous Th | 2019 |
Lower extremity hemorrhage in patients with spinal cord injury receiving enoxaparin therapy.
Topics: Adult; Aged; Anticoagulants; Enoxaparin; Hemorrhage; Humans; Lower Extremity; Male; Middle Aged; Spi | 2015 |
Inhibitors of slit protein interactions with the heparan sulphate proteoglycan glypican-1: potential agents for the treatment of spinal cord injury.
Topics: Anticoagulants; Dalteparin; Dextran Sulfate; Drug Design; Enoxaparin; Fondaparinux; Glycoproteins; G | 2010 |
Gold Medal Forum Winner. Unfractionated heparin three times a day versus enoxaparin in the prevention of deep vein thrombosis in trauma patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Cost Savings; Enoxaparin; Female; Head I | 2010 |
Enoxaparin versus tinzaparin for venous thromboembolic prophylaxis during rehabilitation after acute spinal cord injury: a retrospective cohort study comparing safety and efficacy.
Topics: Adult; Dose-Response Relationship, Drug; Drug Administration Schedule; Enoxaparin; Female; Fibrinoly | 2012 |
A comparison of heparin/warfarin and enoxaparin thromboprophylaxis in spinal cord injury: the Sheffield experience.
Topics: Acute Disease; Adolescent; Adult; Anticoagulants; Child; Cohort Studies; Comorbidity; Drug Therapy, | 2002 |
Medroxyprogesterone acetate, enoxaparin and pentoxyfylline cause alterations in lipid peroxidation, paraoxonase (PON1) activities and homocysteine levels in the acute oxidative stress in an experimental model of spinal cord injury.
Topics: Animals; Antioxidants; Enoxaparin; Homocysteine; Lipid Peroxidation; Male; Medroxyprogesterone Aceta | 2002 |
Daily vs twice daily enoxaparin in the prevention of venous thromboembolic disorders during rehabilitation following acute spinal cord injury.
Topics: Drug Administration Schedule; Enoxaparin; Female; Fibrinolytic Agents; Gastrointestinal Hemorrhage; | 2004 |
Dalteparin versus enoxaparin for venous thromboembolism prophylaxis in acute spinal cord injury and major orthopedic trauma patients: 'DETECT' trial.
Topics: Adult; Cohort Studies; Dalteparin; Drug Administration Schedule; Enoxaparin; Female; Fibrinolytic Ag | 2007 |
Treatment of acute deep vein thrombosis in spinal cord injured patients with enoxaparin: a cost analysis.
Topics: Adult; Anticoagulants; Cost-Benefit Analysis; Costs and Cost Analysis; Enoxaparin; Female; Heparin; | 1998 |
Prophylaxis of thromboembolism in spinal injuries--results of enoxaparin used in 276 patients.
Topics: Acute Disease; Adult; Anticoagulants; Enoxaparin; Female; Humans; Male; Middle Aged; Pulmonary Embol | 2001 |
Cost comparison of tinzaparin versus enoxaparin as deep venous thrombosis prophylaxis in spinal cord injury: preliminary data.
Topics: Cost-Benefit Analysis; Data Collection; Drug Administration Schedule; Enoxaparin; Fibrinolytic Agent | 2001 |
[Pregnancy and childbirth in a patient with a spinal cord lesion].
Topics: Adult; Dalteparin; Delivery, Obstetric; Female; Humans; Infant, Newborn; Labor, Obstetric; Male; Pre | 2008 |
Dalteparin vs low-dose unfractionated heparin for prophylaxis against clinically evident venous thromboembolism in acute traumatic spinal cord injury: a retrospective cohort study.
Topics: Acute Disease; Adult; Aged; Anticoagulants; Cohort Studies; Dalteparin; Female; Heparin; Humans; Inc | 2008 |