Page last updated: 2024-10-18

dalteparin and Hip Fractures

dalteparin has been researched along with Hip Fractures in 39 studies

Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)

Hip Fractures: Fractures of the FEMUR HEAD; the FEMUR NECK; (FEMORAL NECK FRACTURES); the trochanters; or the inter- or subtrochanteric region. Excludes fractures of the acetabulum and fractures of the femoral shaft below the subtrochanteric region (FEMORAL FRACTURES).

Research Excerpts

ExcerptRelevanceReference
"In patients undergoing surgery for hip fracture, fondaparinux was more effective than enoxaparin in preventing venous thromboembolism and equally safe."9.09Fondaparinux compared with enoxaparin for the prevention of venous thromboembolism after hip-fracture surgery. ( Bauer, KA; Eriksson, BI; Lassen, MR; Turpie, AG, 2001)
"To compare the efficacy and safety of aspirin with rivaroxaban following treatment with enoxaparin for prevention of venous thromboembolism (VTE) after hip fracture surgery (HFS)."7.91Comparison of the Efficacy and Safety of Aspirin and Rivaroxaban Following Enoxaparin Treatment for Prevention of Venous Thromboembolism after Hip Fracture Surgery. ( Huang, Q; Shen, B; Si, HB; Xing, SX; Zeng, Y; Zhou, ZK, 2019)
"The selective antithrombotic fondaparinux is more effective than the low-molecular-weight heparin enoxaparin for prevention of venous thromboembolism (deep-vein thrombosis [DVT] or pulmonary embolism) in patients undergoing major orthopedic surgery, but its cost-effectiveness is undetermined."7.72The cost-effectiveness of fondaparinux compared with enoxaparin as prophylaxis against thromboembolism following major orthopedic surgery. ( Borris, L; Bossuyt, P; de Pouvourville, G; Gordois, A; Jönsson, B; Levy, E; Posnett, J, 2003)
"The aim of the EXTEND study was to assess safety and efficacy of extended administration (35 days) of ximelagatran or enoxaparin for the prevention of venous thromboembolism after elective hip replacement and hip fracture surgery."5.14Safety assessment of new antithrombotic agents: lessons from the EXTEND study on ximelagatran. ( Agnelli, G; Andersson, M; Bergqvist, D; Boberg, B; Bylock, A; Cohen, AT; Dahl, OE; Eriksson, BI; Jensen, E; Lassen, MR; Mouret, P; Rosencher, N, 2009)
"In patients undergoing surgery for hip fracture, fondaparinux was more effective than enoxaparin in preventing venous thromboembolism and equally safe."5.09Fondaparinux compared with enoxaparin for the prevention of venous thromboembolism after hip-fracture surgery. ( Bauer, KA; Eriksson, BI; Lassen, MR; Turpie, AG, 2001)
" The incidence of VTE and hematoma formation was evaluated and compared between patients who received aspirin versus enoxaparin or heparin."4.12Does Aspirin Provide Adequate Chemoprophylaxis for Venous Thromboembolic Events in Operative Pelvic and Acetabular Fractures? ( Du, JY; Metcalf, KB; Ochenjele, G, 2022)
"To compare the efficacy and safety of aspirin with rivaroxaban following treatment with enoxaparin for prevention of venous thromboembolism (VTE) after hip fracture surgery (HFS)."3.91Comparison of the Efficacy and Safety of Aspirin and Rivaroxaban Following Enoxaparin Treatment for Prevention of Venous Thromboembolism after Hip Fracture Surgery. ( Huang, Q; Shen, B; Si, HB; Xing, SX; Zeng, Y; Zhou, ZK, 2019)
"The selective antithrombotic fondaparinux is more effective than the low-molecular-weight heparin enoxaparin for prevention of venous thromboembolism (deep-vein thrombosis [DVT] or pulmonary embolism) in patients undergoing major orthopedic surgery, but its cost-effectiveness is undetermined."3.72The cost-effectiveness of fondaparinux compared with enoxaparin as prophylaxis against thromboembolism following major orthopedic surgery. ( Borris, L; Bossuyt, P; de Pouvourville, G; Gordois, A; Jönsson, B; Levy, E; Posnett, J, 2003)
"Edoxaban is an oral, direct, once-daily factor Xa inhibitor."2.79Safety and efficacy of edoxaban in patients undergoing hip fracture surgery. ( Abe, K; Fuji, T; Fujita, S; Kawai, Y; Kimura, T; Kiuchi, Y; Nakamura, M; Tachibana, S, 2014)
" The purpose of this study was to assess the impact of the route of administration and dosage regimen on the compliance to the prescription."1.56Extended thromboprophylaxis for hip or knee arthroplasty. Does the administration route and dosage regimen affect adherence? A cohort study. ( Bautista, M; Bonilla, G; Castro, J; Llinás, A; Moreno, JP, 2020)
"To evaluate the rates of deep vein thrombosis (DVT) and pulmonary embolism (PE) in hip fracture patients receiving mechanical thromboprophylaxis."1.36Mechanical thromboprophylaxis for patients undergoing hip fracture surgery. ( Lee, HC; Loh, JS; Mehta, KV, 2010)
"Fondaparinux sodium is a new antithrombotic agent that is indicated for prophylaxis of VTE after major orthopedic surgery."1.33Fondaparinux sodium compared with enoxaparin sodium: a cost-effectiveness analysis. ( Bjorvatn, A; Kristiansen, F, 2005)
" The rates of minor bleeding complications in the aspirin group, the < 12-hour postoperative dosing of the enoxaparin group, and the 12 to 24-hour postoperative dosing of the enoxaparin group were 3."1.32Postoperative deep vein thrombosis prophylaxis: a retrospective analysis in 1000 consecutive hip fracture patients treated in a community hospital setting. ( Ennis, RS, 2003)
" Incremental cost-effectiveness ratio calculations demonstrate that warfarin dosed to an international normalized ratio of 2-2."1.31Cost effectiveness of deep venous thrombosis prophylaxis after hip fracture. ( Chisholm, MA; Wade, WE, 2000)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (5.13)18.2507
2000's18 (46.15)29.6817
2010's13 (33.33)24.3611
2020's6 (15.38)2.80

Authors

AuthorsStudies
Haentjens, P1
San Juan Alvarez, M1
Márquez Garrido, G1
Rodríguez Bertos, C1
González Pérez, L1
Abatzis-Papadopoulos, M1
Tigkiropoulos, K1
Nikas, S1
Papoutsis, I1
Kostopoulou, O1
Stavridis, K1
Karamanos, D1
Lazaridis, I1
Saratzis, N1
Metcalf, KB1
Du, JY1
Ochenjele, G1
Joo, PY1
Modrak, M1
Park, N1
Brand, J1
Rubin, LE1
Grauer, JN1
Bernstein, JA1
Sivro, M1
Omerović, Đ1
Lazović, F1
Papović, A1
Huang, Q1
Xing, SX1
Zeng, Y1
Si, HB1
Zhou, ZK1
Shen, B1
Moreno, JP1
Bautista, M1
Castro, J1
Bonilla, G1
Llinás, A1
Mula, V1
Parikh, S1
Suresh, S1
Bottle, A1
Loeffler, M1
Alam, M1
Tang, Y1
Wang, K1
Shi, Z1
Yang, P1
Dang, X1
Campbell, ST1
Bala, A1
Jiang, SY1
Gardner, MJ1
Bishop, JA1
Zhang, Z1
Li, Z1
Li, J1
Liu, L1
Feldinger, LE1
Fuji, T1
Fujita, S1
Kawai, Y1
Nakamura, M1
Kimura, T1
Kiuchi, Y1
Abe, K1
Tachibana, S1
Comp, P1
Happe, LE1
Sarnes, M1
Farrelly, E1
Granero Xiberta, J1
Soler Minoves, JM1
Garcia Nuño, L1
Knesek, MJ1
Litinas, E1
Adiguzel, C1
Hopkinson, W1
Hoppensteadt, D1
Lassen, M1
Fareed, J1
Oztürk, A1
Ozkan, Y1
Akgöz, S1
Yalçin, N1
Aykut, S1
Ozdemir, MR1
Mehta, KV1
Lee, HC1
Loh, JS1
Willard, RN1
Muñiz, AE1
Chuidian, F1
Lassen, MR5
Fisher, W1
Mouret, P3
Agnelli, G3
George, D1
Kakkar, A1
Mismetti, P2
Turpie, AG4
Bauer, KA2
Eriksson, BI5
Ennis, RS1
Gordois, A1
Posnett, J1
Borris, L1
Bossuyt, P1
Jönsson, B1
Levy, E1
de Pouvourville, G1
Sullivan, SD1
Davidson, BL1
Kahn, SR2
Muntz, JE1
Oster, G1
Raskob, G1
DeWitt, E1
Adams, J1
Bostwick, C1
O'Dell, M1
Bjorvatn, A1
Kristiansen, F1
Schiff, RL1
Shrier, I1
Strulovitch, C1
Hammouda, W1
Cohen, E1
Zukor, D1
Jeong, GK1
Gruson, KI1
Egol, KA1
Aharonoff, GB1
Karp, AH1
Zuckerman, JD1
Koval, KJ1
Cohen, AT1
Bergqvist, D1
Dahl, OE1
Rosencher, N1
Andersson, M1
Bylock, A1
Jensen, E1
Boberg, B1
Finsen, V2
Murashige, N1
Kami, M1
Tvito, A1
Bakchoul, T1
Rowe, JM1
Greinacher, A1
Ganzel, C1
Magnusson, M1
Kälebo, P1
Sivertsson, R1
Wade, WE1
Chisholm, MA1
Fisher, WD1
George, DJ1
Kakkar, AK1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase 3, Randomized, Open Label, Safety and Efficacy Study of the Oral Factor Xa Inhibitor DU-176b Compared With Enoxaparin Sodium for Prevention of Venous Thromboembolism in Patients After Hip Fracture Surgery (STARS J-4 Trial)[NCT01181141]Phase 392 participants (Actual)Interventional2008-10-31Completed
A Multinational, Multicenter, Randomized, Double-Blind Study Comparing the Efficacy and Safety of AVE5026 With Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Elective Total Hip Replacement Surgery[NCT00697099]Phase 32,326 participants (Actual)Interventional2008-06-30Completed
A Multinational, Multicenter, Randomized, Double-Blind Study Comparing the Efficacy and Safety of AVE5026 With Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Hip Fracture Surgery[NCT00721760]Phase 31,003 participants (Actual)Interventional2008-07-31Completed
A Multinational, Multicenter, Randomized, Double-blind Study Comparing the Efficacy and Safety of Semuloparin (AVE5026) With Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Elective Knee Replacement Surgery[NCT00718224]Phase 31,150 participants (Actual)Interventional2008-07-31Completed
"The EXTEND Study: A Randomized, Double-blind, Parallel-group, Phase III b, Multi-centre Study Evaluating Extended Prophylactic Treatment With Melagatran/Ximelagatran Versus Enoxaparin for the Prevention of Venous Thromboembolic Events in Patients Undergo[NCT00206089]Phase 33,300 participants Interventional2005-09-30Terminated (stopped due to Melagatran/ximelagatran was withdrawn from the market and clinical development in February 2006 in the interest of patient safety.)
The Use of Fondaparinux in Preventing Thromboembolism in High Risk Trauma Patients[NCT00531843]Phase 2/Phase 3105 participants (Actual)Interventional2007-12-31Completed
A Multinational, Multicenter, Randomized, Double-Blind Study Comparing the Efficacy and Safety of AVE5026 With Placebo for the Extended Prevention of Venous Thromboembolism in Patients Having Undergone Hip Fracture Surgery[NCT00709904]Phase 3469 participants (Actual)Interventional2008-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

The Incidence of Major or Clinically Relevant Non-major Bleeding

Bleeding events during the period from the start of treatment with the study drug (study treatment) to the day of the follow-up examination were assessed as the primary endpoints. (NCT01181141)
Timeframe: 2 weeks

Interventionpercentage of subjects with bleeds (Number)
DU-176b3.4
Enoxaparin Sodium6.9

Increased Bleeding Attributed to Fondaparinux

Coagulopathic bleeding due to fondaparinux was suspected in patients requiring packed red cell transfusions after initiation of fondaparinux therapy only if the change in hematocrit prompting transfusion was not clinically commensurate with the degree of injuries that the patient had sustained (primarily orthopaedic) and/or the hematocrit did not respond appropriately post-transfusion. (NCT00531843)
Timeframe: 3 weeks post injury

Interventionparticipants (Number)
Fondaparinux Sodium0

Normal Trough and Peak Fondaparinux Concentration

Serum samples were collected 30 minutes before (trough) and 2 hours after (peak) the third dose of fondaparinux. Normative data plots comparing study participants with healthy volunteers were supplied by the company outsourced to analyze samples. (NCT00531843)
Timeframe: Day 3

InterventionParticipants (Number)
Trough values outside normative rangePeak values outside normative range
Fondaparinux Sodium00

Presence of Deep Vein Thrombosis (DVT) or Pulmonary Embolus (PE)

Color-flow duplex venous ultrasonography examinations of upper and lower extremities were performed within 48 hours of injury, and then weekly until discharge or 3 weeks. DVT was defined as any clot occurring in the subclavian, iliac, femoral, or popliteal location. Patients were examined daily for clinical signs and symptoms of venous thromboembolism (VTE) and PE. Small, nonocclusive clots discovered in other locations were observed for progression on sequential ultrasonography examinations. (NCT00531843)
Timeframe: within 3 weeks post injury

,
Interventionparticipants (Number)
DVTDVT after fondaparinuxPE
Fondaparinux Sodium210
No Fondaparinux2NA0

Reviews

3 reviews available for dalteparin and Hip Fractures

ArticleYear
The effectiveness and safety of direct oral anticoagulants compared to conventional pharmacologic thromboprophylaxis in hip fracture patients: A systematic review and meta-analysis of randomized controlled trials.
    Orthopaedics & traumatology, surgery & research : OTSR, 2023, Volume: 109, Issue:2

    Topics: Anticoagulants; Enoxaparin; Hemorrhage; Heparin, Low-Molecular-Weight; Hip Fractures; Humans; Random

2023
Fondaparinux vs enoxaparin for the prevention of venous thromboembolism in major orthopedic surgery: a meta-analysis of 4 randomized double-blind studies.
    Archives of internal medicine, 2002, Sep-09, Volume: 162, Issue:16

    Topics: Aged; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Confidence In

2002
Improvements in the prevention of postoperative venous thromboembolism in hip fracture patients.
    Orthopedics, 2003, Volume: 26, Issue:8 Suppl

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anticoagulants; Clinical Trials, Phase III

2003

Trials

8 trials available for dalteparin and Hip Fractures

ArticleYear
Thromboembolic prophylaxis in orthopaedic trauma patients: a comparison between a fixed dose and an individually adjusted dose of a low molecular weight heparin (nadroparin calcium)
    Injury, 1996, Volume: 27, Issue:6

    Topics: Aged; Anticoagulants; Drug Administration Schedule; Female; Hip Fractures; Humans; Leg Injuries; Mal

1996
A RCT study of Rivaroxaban, low-molecular-weight heparin, and sequential medication regimens for the prevention of venous thrombosis after internal fixation of hip fracture.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 92

    Topics: Aged; Aged, 80 and over; China; Cost-Benefit Analysis; Double-Blind Method; Drug Administration Sche

2017
Safety and efficacy of edoxaban in patients undergoing hip fracture surgery.
    Thrombosis research, 2014, Volume: 133, Issue:6

    Topics: Aged; Blood Loss, Surgical; Drug Administration Schedule; Enoxaparin; Factor Xa Inhibitors; Female;

2014
Inflammatory biomarker profiling in elderly patients with acute hip fracture treated with heparins.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2010, Volume: 16, Issue:1

    Topics: Acute Disease; Acute-Phase Proteins; Aged; Aged, 80 and over; Anticoagulants; Arthroplasty, Replacem

2010
Semuloparin for prevention of venous thromboembolism after major orthopedic surgery: results from three randomized clinical trials, SAVE-HIP1, SAVE-HIP2 and SAVE-KNEE.
    Journal of thrombosis and haemostasis : JTH, 2012, Volume: 10, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Dou

2012
Semuloparin for prevention of venous thromboembolism after major orthopedic surgery: results from three randomized clinical trials, SAVE-HIP1, SAVE-HIP2 and SAVE-KNEE.
    Journal of thrombosis and haemostasis : JTH, 2012, Volume: 10, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Dou

2012
Semuloparin for prevention of venous thromboembolism after major orthopedic surgery: results from three randomized clinical trials, SAVE-HIP1, SAVE-HIP2 and SAVE-KNEE.
    Journal of thrombosis and haemostasis : JTH, 2012, Volume: 10, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Dou

2012
Semuloparin for prevention of venous thromboembolism after major orthopedic surgery: results from three randomized clinical trials, SAVE-HIP1, SAVE-HIP2 and SAVE-KNEE.
    Journal of thrombosis and haemostasis : JTH, 2012, Volume: 10, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Dou

2012
Semuloparin for prevention of venous thromboembolism after major orthopedic surgery: results from three randomized clinical trials, SAVE-HIP1, SAVE-HIP2 and SAVE-KNEE.
    Journal of thrombosis and haemostasis : JTH, 2012, Volume: 10, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Dou

2012
Semuloparin for prevention of venous thromboembolism after major orthopedic surgery: results from three randomized clinical trials, SAVE-HIP1, SAVE-HIP2 and SAVE-KNEE.
    Journal of thrombosis and haemostasis : JTH, 2012, Volume: 10, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Dou

2012
Semuloparin for prevention of venous thromboembolism after major orthopedic surgery: results from three randomized clinical trials, SAVE-HIP1, SAVE-HIP2 and SAVE-KNEE.
    Journal of thrombosis and haemostasis : JTH, 2012, Volume: 10, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Dou

2012
Semuloparin for prevention of venous thromboembolism after major orthopedic surgery: results from three randomized clinical trials, SAVE-HIP1, SAVE-HIP2 and SAVE-KNEE.
    Journal of thrombosis and haemostasis : JTH, 2012, Volume: 10, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Dou

2012
Semuloparin for prevention of venous thromboembolism after major orthopedic surgery: results from three randomized clinical trials, SAVE-HIP1, SAVE-HIP2 and SAVE-KNEE.
    Journal of thrombosis and haemostasis : JTH, 2012, Volume: 10, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Dou

2012
Safety assessment of new antithrombotic agents: lessons from the EXTEND study on ximelagatran.
    Thrombosis research, 2009, Volume: 123, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alanine Transaminase; Anticoagulants; Arthroplasty, Replacement, Hip

2009
Fondaparinux compared with enoxaparin for the prevention of venous thromboembolism after hip-fracture surgery.
    The New England journal of medicine, 2001, Nov-01, Volume: 345, Issue:18

    Topics: Aged; Double-Blind Method; Enoxaparin; Female; Fibrinolytic Agents; Fondaparinux; Hemorrhage; Hip Fr

2001
Extended venous thromboembolism prophylaxis in patients undergoing hip fracture surgery - the SAVE-HIP3 study.
    The bone & joint journal, 2013, Volume: 95-B, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Fibrinolytic Agents; Hepari

2013

Other Studies

28 other studies available for dalteparin and Hip Fractures

ArticleYear
[Hip fracture during pregancy in a woman with transient osteporosis].
    Revista espanola de anestesiologia y reanimacion, 2010, Volume: 57, Issue:5

    Topics: Accidental Falls; Adult; Anticoagulants; Bone Screws; Cesarean Section; Female; Fracture Fixation, I

2010
Does Aspirin Provide Adequate Chemoprophylaxis for Venous Thromboembolic Events in Operative Pelvic and Acetabular Fractures?
    The Iowa orthopaedic journal, 2022, Volume: 42, Issue:1

    Topics: Anticoagulants; Aspirin; Chemoprevention; Enoxaparin; Hematoma; Heparin; Hip Fractures; Humans; Pelv

2022
Comparing Venous Thromboembolism Prophylactic Agents After Hip Fracture Surgery: A National Database Study.
    Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 2022, 12-01, Volume: 6, Issue:12

    Topics: Anticoagulants; Enoxaparin; Hip Fractures; Humans; Venous Thromboembolism; Warfarin

2022
The effects of three different low-molecular-weight heparins on blood loss after intramedullary nailing of trochanteric fractures.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2023, Volume: 33, Issue:8

    Topics: Anticoagulants; Blood Loss, Surgical; Bone Nails; Dalteparin; Enoxaparin; Fracture Fixation, Intrame

2023
Comparison of the Efficacy and Safety of Aspirin and Rivaroxaban Following Enoxaparin Treatment for Prevention of Venous Thromboembolism after Hip Fracture Surgery.
    Orthopaedic surgery, 2019, Volume: 11, Issue:5

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Drug Ther

2019
Extended thromboprophylaxis for hip or knee arthroplasty. Does the administration route and dosage regimen affect adherence? A cohort study.
    International orthopaedics, 2020, Volume: 44, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Arthroplasty, Repl

2020
Venous thromboembolism rates after hip and knee arthroplasty and hip fractures.
    BMC musculoskeletal disorders, 2020, Feb-12, Volume: 21, Issue:1

    Topics: Aged; Aged, 80 and over; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement,

2020
Are factor Xa inhibitors effective thromboprophylaxis following hip fracture surgery?: A large national database study.
    Injury, 2017, Volume: 48, Issue:12

    Topics: Aged; Aged, 80 and over; Anticoagulants; Arthroplasty, Replacement, Hip; Databases, Factual; Enoxapa

2017
Effects of Natural Hirudin and Low Molecular Weight Heparin in Preventing Deep Venous Thrombosis in Aged Patients with Intertrochanteric Fracture.
    Scientific reports, 2018, 06-11, Volume: 8, Issue:1

    Topics: Aged; Anticoagulants; Enoxaparin; Female; Fibrin Fibrinogen Degradation Products; Hip Fractures; Hir

2018
Recurrent and consistent improvement of cognitive impairment and depression after short time of treatment with enoxaparin.
    Journal of the American Geriatrics Society, 2013, Volume: 61, Issue:7

    Topics: Accidental Falls; Aged, 80 and over; Anticoagulants; Cognition Disorders; Depression; Enoxaparin; Hi

2013
Venous thromboembolism clinically detected after hip fracture surgery with prophylaxis in a clinical practice setting.
    American journal of orthopedics (Belle Mead, N.J.), 2008, Volume: 37, Issue:9

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Anticoagulants; Cohort Studies; Dalteparin; Enoxapari

2008
[Thromboembolic disease in orthopedic surgery].
    Medicina clinica, 2008, Volume: 131 Suppl 2

    Topics: Anesthesia, Conduction; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Early Ambul

2008
The effect of blood albumin and total lymphocyte count on short-term results in elderly patients with hip fractures.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2009, Volume: 15, Issue:6

    Topics: Aged; Aged, 80 and over; Anticoagulants; Enoxaparin; Female; Hip Fractures; Humans; Lymphocyte Count

2009
Mechanical thromboprophylaxis for patients undergoing hip fracture surgery.
    Journal of orthopaedic surgery (Hong Kong), 2010, Volume: 18, Issue:3

    Topics: Aged; Aged, 80 and over; Cohort Studies; Enoxaparin; Female; Fibrinolytic Agents; Fracture Fixation;

2010
Delayed subdural hematoma after receiving enoxaparin for prevention of thromboembolic events from high-risk surgery.
    The American journal of emergency medicine, 2012, Volume: 30, Issue:6

    Topics: Aged; Emergency Service, Hospital; Enoxaparin; Fibrinolytic Agents; Hematoma, Subdural, Acute; Hip F

2012
Postoperative deep vein thrombosis prophylaxis: a retrospective analysis in 1000 consecutive hip fracture patients treated in a community hospital setting.
    Journal of the Southern Orthopaedic Association, 2003,Spring, Volume: 12, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Cohort Studies; Enoxaparin; Female; Frac

2003
The cost-effectiveness of fondaparinux compared with enoxaparin as prophylaxis against thromboembolism following major orthopedic surgery.
    Journal of thrombosis and haemostasis : JTH, 2003, Volume: 1, Issue:10

    Topics: Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Cohort Studies; Cos

2003
A cost-effectiveness analysis of fondaparinux sodium compared with enoxaparin sodium as prophylaxis against venous thromboembolism: use in patients undergoing major orthopaedic surgery.
    PharmacoEconomics, 2004, Volume: 22, Issue:9

    Topics: Aged; Aged, 80 and over; Anticoagulants; Clinical Trials as Topic; Cohort Studies; Cost-Benefit Anal

2004
Gastrointestinal bleeding in an elderly patient with a recent hip replacement.
    Journal of the Mississippi State Medical Association, 2004, Volume: 45, Issue:12

    Topics: Aged; Aged, 80 and over; Anticoagulants; Arthroplasty, Replacement, Hip; Contraindications; Diagnosi

2004
Fondaparinux sodium compared with enoxaparin sodium: a cost-effectiveness analysis.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2005, Volume: 5, Issue:2

    Topics: Aged; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Cost-Benefit

2005
Identifying orthopedic patients at high risk for venous thromboembolism despite thromboprophylaxis.
    Chest, 2005, Volume: 128, Issue:5

    Topics: Adult; Aged, 80 and over; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement,

2005
Thromboprophylaxis after hip fracture: evaluation of 3 pharmacologic agents.
    American journal of orthopedics (Belle Mead, N.J.), 2007, Volume: 36, Issue:3

    Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Dextrans; Enoxaparin; Female; Fibrinolytic Agents;

2007
[Thrombosis prophylaxis in orthopedic surgery].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2000, Feb-20, Volume: 120, Issue:5

    Topics: Dalteparin; Dextrans; Enoxaparin; Femoral Fractures; Fibrinolytic Agents; Heparin, Low-Molecular-Wei

2000
Duration of thrombosis prophylaxis in orthopaedic surgery.
    Annales chirurgiae et gynaecologiae, 2001, Volume: 90, Issue:2

    Topics: Anticoagulants; Arthroplasty, Replacement, Hip; Drug Administration Schedule; Enoxaparin; Hip Fractu

2001
Prevention of venous thromboembolism with fondaparinux.
    The New England journal of medicine, 2002, Mar-21, Volume: 346, Issue:12

    Topics: Drug Administration Schedule; Enoxaparin; Fibrinolytic Agents; Fondaparinux; Hip Fractures; Humans;

2002
Severe and persistent heparin-induced thrombocytopenia despite fondaparinux treatment.
    American journal of hematology, 2015, Volume: 90, Issue:7

    Topics: Aged, 80 and over; Antibodies; Anticoagulants; Blood Platelets; Dalteparin; Female; Fondaparinux; Hi

2015
Is colour Doppler ultrasound a sensitive screening method in diagnosing deep vein thrombosis after hip surgery?
    Thrombosis and haemostasis, 1996, Volume: 75, Issue:2

    Topics: Anticoagulants; Dalteparin; Dextrans; Hip Fractures; Hip Prosthesis; Hirudin Therapy; Hirudins; Huma

1996
Cost effectiveness of deep venous thrombosis prophylaxis after hip fracture.
    American journal of orthopedics (Belle Mead, N.J.), 2000, Volume: 29, Issue:5

    Topics: Anticoagulants; Cost-Benefit Analysis; Dalteparin; Hip Fractures; Humans; Leg; Postoperative Complic

2000