Page last updated: 2024-10-18

dalteparin and HbS Disease

dalteparin has been researched along with HbS Disease in 8 studies

Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)

Research Excerpts

ExcerptRelevanceReference
"Sickle cell disease is one of the most common and severe genetic disorders in the world."2.52Low-molecular-weight heparins for managing vaso-occlusive crises in people with sickle cell disease. ( Fedorowicz, Z; van Zuuren, EJ, 2015)
"Pain is the most prominent symptom of vasoocclusion, and hypercoagulability is a well-established pathogenic phenomenon in people with sickle cell disease."2.50Low-molecular-weight heparins for managing vasoocclusive crises in people with sickle cell disease: a summary of a cochrane systematic review. ( Fedorowicz, Z; van Zuuren, EJ, 2014)
"Sickle cell disease is one of the most common and severe genetic disorders in the world."2.49Low-molecular-weight heparins for managing vaso-occlusive crises in people with sickle cell disease. ( Fedorowicz, Z; van Zuuren, EJ, 2013)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's5 (62.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Sakon, C1
Nikirk, M1
O'Brien, ARW1
Vianello, A1
Vencato, E1
Cantini, M1
Zanconato, G1
Manfrin, E1
Zamo, A1
Zorzi, F1
Mazzi, F1
Martinelli, N1
Cavaliere, E1
Monari, F1
Venturelli, D1
Ferrara, F1
Olivieri, O1
De Franceschi, L1
Alli, NA1
Wainwright, RD1
Mackinnon, D1
Poyiadjis, S1
Naidu, G1
van Zuuren, EJ3
Fedorowicz, Z3
Telen, MJ1
Batchvarova, M1
Shan, S1
Bovee-Geurts, PH1
Zennadi, R1
Leitgeb, A1
Brock, R1
Lindgren, M1
Qari, MH1
Aljaouni, SK1
Alardawi, MS1
Fatani, H1
Alsayes, FM1
Zografos, P1
Alsaigh, M1
Alalfi, A1
Alamin, M1
Gadi, A1
Mousa, SA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Randomized, Double-blind, Placebo Controlled, Multi-national Study of Therapeutic Anticoagulation Strategy for Acute Chest Syndrome in Adults[NCT02580773]Phase 3200 participants (Anticipated)Interventional2016-12-16Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for dalteparin and HbS Disease

ArticleYear
Skull bone infarctive crisis and deep vein thrombosis in homozygous sickle cell disease- case report and review of the literature.
    Hematology (Amsterdam, Netherlands), 2007, Volume: 12, Issue:2

    Topics: Anemia, Sickle Cell; Anticoagulants; Catheterization; Child; Diagnosis, Differential; Edema; Enoxapa

2007
Low-molecular-weight heparins for managing vaso-occlusive crises in people with sickle cell disease.
    The Cochrane database of systematic reviews, 2015, Dec-18, Issue:12

    Topics: Anemia, Sickle Cell; Anticoagulants; Dalteparin; Heparin, Low-Molecular-Weight; Humans; Pain Measure

2015
Low-molecular-weight heparins for managing vaso-occlusive crises in people with sickle cell disease.
    The Cochrane database of systematic reviews, 2013, Jun-12, Issue:6

    Topics: Anemia, Sickle Cell; Anticoagulants; Heparin, Low-Molecular-Weight; Humans; Peripheral Vascular Dise

2013
Low-molecular-weight heparins for managing vasoocclusive crises in people with sickle cell disease: a summary of a cochrane systematic review.
    Hemoglobin, 2014, Volume: 38, Issue:3

    Topics: Anemia, Sickle Cell; Female; Fibrinolytic Agents; Hemolysis; Heparin, Low-Molecular-Weight; Humans;

2014

Trials

1 trial available for dalteparin and HbS Disease

ArticleYear
Reduction of painful vaso-occlusive crisis of sickle cell anaemia by tinzaparin in a double-blind randomized trial.
    Thrombosis and haemostasis, 2007, Volume: 98, Issue:2

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Antisickling Agents; Double-Blind Method; Female; Fibrinolyt

2007

Other Studies

3 other studies available for dalteparin and HbS Disease

ArticleYear
Enoxaparin adherence for venous thromboembolism prophylaxis in hospitalized patients with sickle cell disease.
    Expert review of hematology, 2023, Volume: 16, Issue:2

    Topics: Adult; Anemia, Sickle Cell; Anticoagulants; Enoxaparin; Humans; Retrospective Studies; Venous Thromb

2023
Improvement of maternal and fetal outcomes in women with sickle cell disease treated with early prophylactic erythrocytapheresis.
    Transfusion, 2018, Volume: 58, Issue:9

    Topics: Abortion, Spontaneous; Adult; Anemia, Sickle Cell; Anticoagulants; Birth Weight; Cross-Sectional Stu

2018
Sevuparin binds to multiple adhesive ligands and reduces sickle red blood cell-induced vaso-occlusion.
    British journal of haematology, 2016, Volume: 175, Issue:5

    Topics: Anemia, Sickle Cell; Animals; Arterial Occlusive Diseases; Cell Adhesion; Cells, Cultured; Endotheli

2016