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dalteparin and Endotoxemia

dalteparin has been researched along with Endotoxemia in 5 studies

Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)

Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.

Research Excerpts

ExcerptRelevanceReference
"However, bleeding was more prominent in the fondaparinux group compared with the enoxaparin group at an equipotent dose for anti-Xa activity."1.38Enoxaparin and fondaparinux attenuates endothelial damage in endotoxemic rats. ( Aihara, K; Iba, T; Kayhanian, H; Ohike, T; Okamoto, K; Tajirika, T; Watanabe, S, 2012)
"The fibrinogen level was maintained at significantly better levels, and the elevation of alanine aminotransferase was significantly suppressed in enoxaparin group (P < 0."1.35Enoxaparin attenuates endothelial damage with less bleeding compared with unfractionated heparin in endotoxemic rats. ( Iba, T; Takayama, T, 2009)
" Herein, we studied the microhemodynamic and cellular mechanisms of this adverse effect of heparin on AT actions by the use of intravital microscopy and granulocyte culturing."1.31Adverse effect of heparin on antithrombin action during endotoxemia: microhemodynamic and cellular mechanisms. ( Dunzendorfer, S; Hoffmann, JN; Inthorn, D; Kaneider, NC; Laschke, MW; Menger, MD; Römisch, J; Schildberg, FW; Vollmar, B; Wiedermann, CJ, 2002)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Hoffmann, JN1
Vollmar, B1
Laschke, MW1
Inthorn, D1
Kaneider, NC1
Dunzendorfer, S1
Wiedermann, CJ1
Römisch, J1
Schildberg, FW1
Menger, MD1
Li, LF1
Liu, YY1
Lin, SW1
Chang, CH1
Chen, NH1
Hung, CY1
Lee, CS1
Iba, T2
Takayama, T1
Okamoto, K1
Ohike, T1
Tajirika, T1
Aihara, K1
Watanabe, S1
Kayhanian, H1
Yeh, YC1
Wang, MJ1
Lin, CP1
Fan, SZ1
Tsai, JC1
Sun, WZ1
Ko, WJ1

Other Studies

5 other studies available for dalteparin and Endotoxemia

ArticleYear
Adverse effect of heparin on antithrombin action during endotoxemia: microhemodynamic and cellular mechanisms.
    Thrombosis and haemostasis, 2002, Volume: 88, Issue:2

    Topics: Animals; Antithrombin III; Cell Communication; Chemotaxis, Leukocyte; Cricetinae; Drug Antagonism; E

2002
Low-Molecular-Weight Heparin Reduces Ventilation-Induced Lung Injury through Hypoxia Inducible Factor-1α in a Murine Endotoxemia Model.
    International journal of molecular sciences, 2020, Apr-28, Volume: 21, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Chemokine CXCL2; Disease Models, Animal; Endotoxemia; Enoxaparin;

2020
Enoxaparin attenuates endothelial damage with less bleeding compared with unfractionated heparin in endotoxemic rats.
    Shock (Augusta, Ga.), 2009, Volume: 32, Issue:5

    Topics: Animals; Anticoagulants; CD13 Antigens; Endothelium; Endotoxemia; Enoxaparin; Fibrinogen; Hemorrhage

2009
Enoxaparin and fondaparinux attenuates endothelial damage in endotoxemic rats.
    The journal of trauma and acute care surgery, 2012, Volume: 72, Issue:1

    Topics: Animals; Anticoagulants; Endothelium, Vascular; Endotoxemia; Enoxaparin; Factor Xa Inhibitors; Fonda

2012
Enoxaparin sodium prevents intestinal microcirculatory dysfunction in endotoxemic rats.
    Critical care (London, England), 2012, Dec-12, Volume: 16, Issue:2

    Topics: Animals; Blood Flow Velocity; Endotoxemia; Enoxaparin; Hemodynamics; Intestines; Lipopolysaccharides

2012