Page last updated: 2024-10-18

dalteparin and Disease Exacerbation

dalteparin has been researched along with Disease Exacerbation in 33 studies

Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)

Research Excerpts

ExcerptRelevanceReference
"Although congenital afibrinogenemia is a rare autosomal recessive bleeding disorder, it can be more frequently encountered in countries where consanguineous marriages are common."7.81A case of congenital afibrinogenemia complicated with thromboembolic events that required repeated amputations. ( Işik, B; Karakukcu, M; Mutlu, FT; Ozdemir, MA; Patiroglu, T; Unal, E; Yilmaz, E, 2015)
"The aim of this study was to examine the effect of the antithrombotic drugs aspirin and enoxaparin on fibrosis progression and regenerative activity in a rat model of liver cirrhosis and to determine if these two drugs are beneficial in animals with advanced fibrosis or with established cirrhosis undergoing partial hepatectomy."7.74The beneficial effect of aspirin and enoxaparin on fibrosis progression and regenerative activity in a rat model of cirrhosis. ( Assy, N; Hussein, O; Khalil, A; Luder, A; Paizi, M; Spira, G; Szvalb, S, 2007)
"ESSENTIALS: Does thrombus stability alter the presentation of venous thromboembolism and do anticoagulants alter this? In a murine model, we imaged a femoral vein thrombus and quantified emboli in the pulmonary arteries."5.43Comparison of the effect of dabigatran and dalteparin on thrombus stability in a murine model of venous thromboembolism. ( Gross, PL; Ni, R; Saldanha, LJ; Shaya, SA; Vaezzadeh, N; Zhou, J, 2016)
"Although congenital afibrinogenemia is a rare autosomal recessive bleeding disorder, it can be more frequently encountered in countries where consanguineous marriages are common."3.81A case of congenital afibrinogenemia complicated with thromboembolic events that required repeated amputations. ( Işik, B; Karakukcu, M; Mutlu, FT; Ozdemir, MA; Patiroglu, T; Unal, E; Yilmaz, E, 2015)
"The aim of this study was to examine the effect of the antithrombotic drugs aspirin and enoxaparin on fibrosis progression and regenerative activity in a rat model of liver cirrhosis and to determine if these two drugs are beneficial in animals with advanced fibrosis or with established cirrhosis undergoing partial hepatectomy."3.74The beneficial effect of aspirin and enoxaparin on fibrosis progression and regenerative activity in a rat model of cirrhosis. ( Assy, N; Hussein, O; Khalil, A; Luder, A; Paizi, M; Spira, G; Szvalb, S, 2007)
" The first received low-molecular-weight heparin for 10 days at therapeutic dosage (nadroparin 180 anti-activated factor X units once daily) and compression therapy for three months, and the second received compression therapy alone."2.75Therapy of isolated calf muscle vein thrombosis: a randomized, controlled study. ( Beyer, J; Buschmann, L; Halbritter, K; Rastan, A; Schellong, S; Schwarz, T, 2010)
" These assays may provide useful markers to guide appropriate dalteparin (and other low-molecular weight heparin) dosing schedules to optimize anticancer effects of dalteparin in APC."2.75Weight-adjusted dalteparin for prevention of vascular thromboembolism in advanced pancreatic cancer patients decreases serum tissue factor and serum-mediated induction of cancer cell invasion. ( Echrish, H; Ettelaie, C; Gardiner, E; Greenman, J; Li, C; Madden, LA; Maraveyas, A, 2010)
"ESSENTIALS: Does thrombus stability alter the presentation of venous thromboembolism and do anticoagulants alter this? In a murine model, we imaged a femoral vein thrombus and quantified emboli in the pulmonary arteries."1.43Comparison of the effect of dabigatran and dalteparin on thrombus stability in a murine model of venous thromboembolism. ( Gross, PL; Ni, R; Saldanha, LJ; Shaya, SA; Vaezzadeh, N; Zhou, J, 2016)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (30.30)29.6817
2010's16 (48.48)24.3611
2020's7 (21.21)2.80

Authors

AuthorsStudies
Wilts, IT1
Hutten, BA1
Meijers, JCM1
Spek, CA1
Büller, HR1
Kamphuisen, PW1
Nagy, Z1
Turcsik, V1
Blaskó, G1
Asero, R1
Tedeschi, A1
Cugno, M1
Schwarz, T1
Buschmann, L1
Beyer, J1
Halbritter, K1
Rastan, A1
Schellong, S1
Chen, S1
Schmidt, B1
Tohoku, S1
Trolese, L1
Bordignon, S1
Chun, KRJ1
Glueck, CJ3
Freiberg, RA3
Wang, P3
Massabeti, R1
Cipriani, MS1
Valenti, I1
Abrams, RMC1
Kim, BD1
Markantone, DM1
Reilly, K1
Paniz-Mondolfi, AE1
Gitman, MR1
Choo, SY1
Tse, W1
Robinson-Papp, J1
Audley, GG1
Frankenfeld, P1
Dlamini, S1
Raubenheimer, P1
Hoare, J1
Cairncross, L1
Van den Berg, R1
Gule, MV1
Calligaro, G1
Sukhdeo, S1
Negroponte, E1
Rajasekhar, H1
Gaur, S1
Horton, DB1
Malhotra, A1
Moorthy, LN1
Qian, C1
Huhtakangas, J1
Juvela, S1
Bode, MK1
Tatlisumak, T1
Savolainen, M1
Numminen, H1
Ollikainen, J1
Luostarinen, L1
Kupila, L1
Tetri, S1
Ohta, H1
Miyake, T1
Shimizu, T1
Sonoda, H1
Ueki, T1
Kaida, S1
Yamaguchi, T1
Iida, H1
Tani, M1
Pastorek, RA1
Cripps, MW1
Bernstein, IH1
Scott, WW1
Madden, CJ1
Rickert, KL1
Wolf, SE1
Phelan, HA1
Ozdemir, MA1
Işik, B1
Patiroglu, T1
Karakukcu, M1
Mutlu, FT1
Yilmaz, E1
Unal, E1
Giuliani, J1
Martelli, S1
Piacentini, P1
Bonetti, A1
Assad, M1
Coffin-Pichonnet, S1
Billotte, C1
Denion, É1
Mir, T1
Layliev, J1
Glickman, LT1
Karow, A1
Hainmann, I1
Nakamura, L1
Budde, U1
Mueller, C1
Zieger, B1
Minshall, CT1
Eriksson, EA1
Leon, SM1
Doben, AR1
McKinzie, BP1
Fakhry, SM1
Gris, JC1
Chauleur, C1
Molinari, N1
Marès, P1
Fabbro-Peray, P1
Quéré, I1
Lefrant, JY1
Haddad, B1
Dauzat, M1
Monroe, VS1
Kerensky, RA1
Rivera, E1
Smith, KM1
Pepine, CJ1
Robert, F1
Busby, E1
Marques, MB1
Reynolds, RE1
Carey, DE1
Sieve, L1
Assy, N1
Hussein, O1
Khalil, A1
Luder, A1
Szvalb, S1
Paizi, M1
Spira, G1
Kinori, M1
Saar, N1
Justo, D1
Almog, R1
de Bièvre, MA1
Vrij, AA1
Schoon, EJ1
Dijkstra, G1
de Jong, AE1
Oberndorff-Klein Woolthuis, AH1
Hemker, HC1
Stockbrügger, RW1
Shaya, SA1
Saldanha, LJ1
Vaezzadeh, N1
Zhou, J1
Ni, R1
Gross, PL1
Maraveyas, A1
Ettelaie, C1
Echrish, H1
Li, C1
Gardiner, E1
Greenman, J1
Madden, LA1
Altinbas, M1
Coskun, HS1
Er, O1
Ozkan, M1
Eser, B1
Unal, A1
Cetin, M1
Soyuer, S1
Wallentin, L1
Lagerqvist, B1
Husted, S1
Kontny, F1
Ståhle, E1
Swahn, E1
Bauer, AT1
Suckau, J1
Frank, K1
Desch, A1
Goertz, L1
Wagner, AH1
Hecker, M1
Goerge, T1
Umansky, L1
Beckhove, P1
Utikal, J1
Gorzelanny, C1
Diaz-Valdes, N1
Umansky, V1
Schneider, SW1
Sprigg, N1
Gray, LJ1
Bath, PM1
Lindenstrøm, E1
Boysen, G1
De Deyn, PP1
Friis, P1
Leys, D1
Marttila, R1
Olsson, JE1
O'Neill, D1
Ringelstein, EB1
van der Sande, JJ1
Turpie, AG1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized, Phase III-b, Multi-centre, Open-label, Parallel Study of Enoxaparin (Low Molecular Weight Heparin) Given Concomitantly With Chemotherapy vs Chemotherapy Alone in Patients With Inoperable Gastric and Gastro-oesophageal Cancer[NCT00718354]Phase 3740 participants (Actual)Interventional2008-07-31Completed
A Clinical Trial of Conservative Versus Routine Invasive Management in Patients With Prior Coronary Artery Bypass Surgery in Patients With a Non-ST Elevation Acute Coronary Syndrome: a Pilot Trial and Registry.[NCT01895751]Phase 460 participants (Actual)Interventional2012-04-30Completed
Evaluation of a Strategy Guided by Imaging Versus Systematic Coronary Angiography in Elderly Patients With Ischemia: a Multicentric Randomized Non Inferiority Trial.[NCT03289728]1,756 participants (Anticipated)Interventional2018-04-04Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for dalteparin and Disease Exacerbation

ArticleYear
Pharmacologic plaque passivation for the reduction of recurrent cardiac events in acute coronary syndromes.
    Journal of the American College of Cardiology, 2003, Feb-19, Volume: 41, Issue:4 Suppl S

    Topics: Abciximab; Acute Disease; Angina, Unstable; Antibodies, Monoclonal; C-Reactive Protein; Coronary Art

2003

Trials

11 trials available for dalteparin and Disease Exacerbation

ArticleYear
Association between protein C levels and mortality in patients with advanced prostate, lung and pancreatic cancer.
    Thrombosis research, 2017, Volume: 154

    Topics: Aged; Anticoagulants; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Disease Progression; Female

2017
The effect of LMWH (Nadroparin) on tumor progression.
    Pathology oncology research : POR, 2009, Volume: 15, Issue:4

    Topics: Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colonic Neoplasms;

2009
Therapy of isolated calf muscle vein thrombosis: a randomized, controlled study.
    Journal of vascular surgery, 2010, Volume: 52, Issue:5

    Topics: Adult; Aged; Anticoagulants; Combined Modality Therapy; Compression Bandages; Disease Progression; D

2010
Early vs. late enoxaparin for the prevention of venous thromboembolism in patients with ICH: A double blind placebo controlled multicenter study.
    Clinical neurology and neurosurgery, 2021, Volume: 202

    Topics: Aged; Aged, 80 and over; Anticoagulants; Cerebral Hemorrhage; Disease Progression; Double-Blind Meth

2021
Addition of enoxaparin to aspirin for the secondary prevention of placental vascular complications in women with severe pre-eclampsia. The pilot randomised controlled NOH-PE trial.
    Thrombosis and haemostasis, 2011, Volume: 106, Issue:6

    Topics: Anticoagulants; Aspirin; Cohort Studies; Disease Progression; Enoxaparin; Female; Follow-Up Studies;

2011
Phase II study of docetaxel plus enoxaparin in chemotherapy-naive patients with metastatic non-small cell lung cancer: preliminary results.
    Lung cancer (Amsterdam, Netherlands), 2003, Volume: 42, Issue:2

    Topics: Aged; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung

2003
Randomized, placebo-controlled trial of low molecular weight heparin in active ulcerative colitis.
    Inflammatory bowel diseases, 2007, Volume: 13, Issue:6

    Topics: Adult; Colitis, Ulcerative; Colonoscopy; Disease Progression; Dose-Response Relationship, Drug; Doub

2007
Weight-adjusted dalteparin for prevention of vascular thromboembolism in advanced pancreatic cancer patients decreases serum tissue factor and serum-mediated induction of cancer cell invasion.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2010, Volume: 21, Issue:5

    Topics: Aged; Dalteparin; Disease Progression; Female; Humans; Male; Middle Aged; Molecular Weight; Neoplasm

2010
A randomized clinical trial of combination chemotherapy with and without low-molecular-weight heparin in small cell lung cancer.
    Journal of thrombosis and haemostasis : JTH, 2004, Volume: 2, Issue:8

    Topics: Adult; Aged; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell;

2004
Outcome at 1 year after an invasive compared with a non-invasive strategy in unstable coronary-artery disease: the FRISC II invasive randomised trial. FRISC II Investigators. Fast Revascularisation during Instability in Coronary artery disease.
    Lancet (London, England), 2000, Jul-01, Volume: 356, Issue:9223

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Coronary Angiography

2000
Outcome at 1 year after an invasive compared with a non-invasive strategy in unstable coronary-artery disease: the FRISC II invasive randomised trial. FRISC II Investigators. Fast Revascularisation during Instability in Coronary artery disease.
    Lancet (London, England), 2000, Jul-01, Volume: 356, Issue:9223

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Coronary Angiography

2000
Outcome at 1 year after an invasive compared with a non-invasive strategy in unstable coronary-artery disease: the FRISC II invasive randomised trial. FRISC II Investigators. Fast Revascularisation during Instability in Coronary artery disease.
    Lancet (London, England), 2000, Jul-01, Volume: 356, Issue:9223

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Coronary Angiography

2000
Outcome at 1 year after an invasive compared with a non-invasive strategy in unstable coronary-artery disease: the FRISC II invasive randomised trial. FRISC II Investigators. Fast Revascularisation during Instability in Coronary artery disease.
    Lancet (London, England), 2000, Jul-01, Volume: 356, Issue:9223

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Coronary Angiography

2000
Stroke severity, early recovery and outcome are each related with clinical classification of stroke: data from the 'Tinzaparin in Acute Ischaemic Stroke Trial' (TAIST).
    Journal of the neurological sciences, 2007, Mar-15, Volume: 254, Issue:1-2

    Topics: Aged; Aged, 80 and over; Brain Infarction; Brain Ischemia; Cerebral Hemorrhage; Disease Progression;

2007

Other Studies

21 other studies available for dalteparin and Disease Exacerbation

ArticleYear
Heparin and tranexamic Acid therapy may be effective in treatment-resistant chronic urticaria with elevated d-dimer: a pilot study.
    International archives of allergy and immunology, 2010, Volume: 152, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Antifibrinolytic Agents; Cetirizine; Chr

2010
Transesophageal echocardiography-guided closure of electrically isolated left atrial appendage to constrain a rapidly growing thrombus despite anticoagulation and sinus rhythm.
    Journal of cardiovascular electrophysiology, 2020, Volume: 31, Issue:1

    Topics: Action Potentials; Aged, 80 and over; Anticoagulants; Atrial Appendage; Atrial Fibrillation; Atrial

2020
Long-term Anticoagulation Prevents Progression of Stages I and II Primary Osteonecrosis of the Hip in Patients With Familial Thrombophilia.
    Orthopedics, 2020, Jul-01, Volume: 43, Issue:4

    Topics: Adult; Anticoagulants; Disease Progression; Enoxaparin; Female; Femur Head Necrosis; Fibrinolysis; F

2020
Covid-19: A systemic disease treated with a wide-ranging approach: A case report.
    Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharmacologie clinique, 2020, Jul-03, Volume: 27, Issue:S Pt 1

    Topics: Adrenal Cortex Hormones; Antibodies, Monoclonal, Humanized; Azithromycin; China; Coronavirus Infecti

2020
Severe rapidly progressive Guillain-Barré syndrome in the setting of acute COVID-19 disease.
    Journal of neurovirology, 2020, Volume: 26, Issue:5

    Topics: Acute Disease; Aged; Anticoagulants; Betacoronavirus; Coronavirus Infections; COVID-19; Disease Prog

2020
Prolonged treatment of COVID-19 pneumonia with high-flow nasal oxygen: A story of oxygen and resilience.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2020, 10-08, Volume: 110, Issue:12

    Topics: Anti-Bacterial Agents; Anticoagulants; Anxiety; Blood Gas Analysis; Cannula; Citalopram; Counseling;

2020
Acute respiratory distress syndrome and COVID-19 in a child with systemic lupus erythematosus.
    Lupus, 2021, Volume: 30, Issue:5

    Topics: Antiviral Agents; Child, Preschool; COVID-19; COVID-19 Drug Treatment; Cytokine Release Syndrome; Cy

2021
The impact of pharmacological thromboprophylaxis and disease-stage on postoperative bleeding following colorectal cancer surgery.
    World journal of surgical oncology, 2019, Jun-27, Volume: 17, Issue:1

    Topics: Aged; Anticoagulants; Colorectal Neoplasms; Disease Progression; Elective Surgical Procedures; Enoxa

2019
The Parkland Protocol's modified Berne-Norwood criteria predict two tiers of risk for traumatic brain injury progression.
    Journal of neurotrauma, 2014, Oct-15, Volume: 31, Issue:20

    Topics: Adult; Aged; Brain Injuries; Clinical Protocols; Disease Progression; Enoxaparin; Female; Fibrinolyt

2014
A case of congenital afibrinogenemia complicated with thromboembolic events that required repeated amputations.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2015, Volume: 26, Issue:3

    Topics: Afibrinogenemia; Amputation, Surgical; Anemia; Anticoagulants; Blood Coagulation Tests; Disease Prog

2015
Medical treatment of osteonecrosis of the knee associated with thrombophilia-hypofibrinolysis.
    Orthopedics, 2014, Volume: 37, Issue:10

    Topics: Adult; Aged; Blood Coagulation Disorders; Disease Progression; Enoxaparin; Female; Fibrinolysis; Fib

2014
Thromboembolic disease in advanced colorectal cancer treated with chemotherapy and bevacizumab: a case of real "pan-thrombosis".
    Tumori, 2015, Mar-20, Volume: 101, Issue:1

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Pro

2015
[Acute unilateral arteritic anterior ischemic optic neuropathy becoming bilateral despite corticosteroid therapy].
    Journal francais d'ophtalmologie, 2016, Volume: 39, Issue:1

    Topics: Acute Disease; Aged; Alzheimer Disease; Anti-Inflammatory Agents; Anticoagulants; Aspirin; Disease P

2016
Massive spontaneous hematoma from chronic enoxaparin (Lovenox) use.
    Plastic and reconstructive surgery, 2010, Volume: 126, Issue:4

    Topics: Abdominal Wall; Acute Kidney Injury; Anticoagulants; Combined Modality Therapy; Disease Progression;

2010
Progressive thrombosis in a 13-year-old girl with trisomy 21 under therapy with low molecular weight heparin.
    Klinische Padiatrie, 2011, Volume: 223, Issue:3

    Topics: Adolescent; Antibodies, Antiphospholipid; Anticoagulants; Antiphospholipid Syndrome; Antithrombins;

2011
Safety and efficacy of heparin or enoxaparin prophylaxis in blunt trauma patients with a head abbreviated injury severity score >2.
    The Journal of trauma, 2011, Volume: 71, Issue:2

    Topics: Abbreviated Injury Scale; Anticoagulants; Brain Injuries; Disease Progression; Enoxaparin; Heparin;

2011
Enoxaparin prevents progression of stages I and II osteonecrosis of the hip.
    Clinical orthopaedics and related research, 2005, Issue:435

    Topics: Arthroplasty, Replacement, Hip; Blood Coagulation Disorders; Disease Progression; Enoxaparin; Female

2005
The beneficial effect of aspirin and enoxaparin on fibrosis progression and regenerative activity in a rat model of cirrhosis.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:5

    Topics: Animals; Aspartate Aminotransferases; Aspirin; Bilirubin; Disease Progression; Enoxaparin; Fibrinoly

2007
Determination of anti-Xa levels in pregnant women treated with low molecular weight heparins for prevention of recurrent venous thromboembolism: a case report and review of the literature.
    Thrombosis research, 2008, Volume: 122, Issue:2

    Topics: Adult; Disease Progression; Enoxaparin; Factor Xa; Factor Xa Inhibitors; Female; Heparin, Low-Molecu

2008
Comparison of the effect of dabigatran and dalteparin on thrombus stability in a murine model of venous thromboembolism.
    Journal of thrombosis and haemostasis : JTH, 2016, Volume: 14, Issue:1

    Topics: Animals; Anticoagulants; Antithrombins; Dabigatran; Dalteparin; Disease Models, Animal; Disease Prog

2016
von Willebrand factor fibers promote cancer-associated platelet aggregation in malignant melanoma of mice and humans.
    Blood, 2015, May-14, Volume: 125, Issue:20

    Topics: ADAM Proteins; ADAMTS13 Protein; Animals; Blood Coagulation; Blood Platelets; Disease Models, Animal

2015