Page last updated: 2024-10-18

dalteparin and Colitis

dalteparin has been researched along with Colitis in 5 studies

Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)

Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.

Research Excerpts

ExcerptRelevanceReference
"Colitis was induced by acetic acid (AA)."5.38Nadroparin sodium activates Nrf2/HO-1 pathway in acetic acid-induced colitis in rats. ( Aygun, C; Bahcecioglu, IH; Demirel, U; Orhan, C; Ozercan, IH; Sahin, K; Tuzcu, M; Yalniz, M, 2012)
"Enoxaparin and heparin significantly ameliorated the severity of dinitrobenzene sulphonic acid- and iodoacetamide-induced colitis as demonstrated by a decrease in mucosal lesion area, colonic weight and mucosal myeloperoxidase and nitric oxide synthase activities."3.71Heparin and low-molecular-weight heparin (enoxaparin) significantly ameliorate experimental colitis in rats. ( Brazowski, E; Dotan, I; Halpern, Z; Hershkoviz, R; Karmeli, F; Peled, Y; Rachmilewitz, D, 2001)
"Histological examination of untreated colitis mice showed a massive loss of crypt architecture and goblet cells, infiltration of immune cells and the presence of edema, while all aspects of this pathology were alleviated by oral enoxaparin."1.42Orally Administered Enoxaparin Ameliorates Acute Colitis by Reducing Macrophage-Associated Inflammatory Responses. ( Eri, RD; Gueven, N; Lean, QY; Patel, RP; Peterson, GM; Randall-Demllo, S; Sohal, SS; Stewart, N, 2015)
"Colitis was induced by acetic acid (AA)."1.38Nadroparin sodium activates Nrf2/HO-1 pathway in acetic acid-induced colitis in rats. ( Aygun, C; Bahcecioglu, IH; Demirel, U; Orhan, C; Ozercan, IH; Sahin, K; Tuzcu, M; Yalniz, M, 2012)
"DSS colitis was induced in Sdc1-deficient (knockout (KO)) and wild-type mice by oral administration of 3% DSS."1.36Enoxaparin improves the course of dextran sodium sulfate-induced colitis in syndecan-1-deficient mice. ( Domschke, W; Floer, M; Gassar, ES; Götte, M; Heidemann, J; Kiesel, L; Kucharzik, T; Luegering, A; Wild, MK, 2010)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yalniz, M1
Demirel, U1
Orhan, C1
Bahcecioglu, IH1
Ozercan, IH1
Aygun, C1
Tuzcu, M1
Sahin, K1
Celasco, G1
Moro, L1
Bozzella, R1
Mangano, K1
Quattrocchi, C1
Aiello, C1
Donia, M1
Fagone, P1
Di Marco, R1
Lean, QY1
Eri, RD1
Randall-Demllo, S1
Sohal, SS1
Stewart, N1
Peterson, GM1
Gueven, N1
Patel, RP1
Floer, M1
Götte, M1
Wild, MK1
Heidemann, J1
Gassar, ES1
Domschke, W1
Kiesel, L1
Luegering, A1
Kucharzik, T1
Dotan, I1
Hershkoviz, R1
Karmeli, F1
Brazowski, E1
Peled, Y1
Rachmilewitz, D1
Halpern, Z1

Other Studies

5 other studies available for dalteparin and Colitis

ArticleYear
Nadroparin sodium activates Nrf2/HO-1 pathway in acetic acid-induced colitis in rats.
    Inflammation, 2012, Volume: 35, Issue:3

    Topics: Acetic Acid; Animals; Colitis; Colon; Cyclooxygenase 2; Heme Oxygenase-1; Inflammatory Bowel Disease

2012
Efficacy of intracolonic administration of low-molecular-weight heparin CB-01-05, compared to other low-molecular-weight heparins and unfractionated heparin, in experimentally induced colitis in rat.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:12

    Topics: Administration, Rectal; Animals; Colitis; Dinitrobenzenes; Disease Models, Animal; Dose-Response Rel

2008
Orally Administered Enoxaparin Ameliorates Acute Colitis by Reducing Macrophage-Associated Inflammatory Responses.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Anticoagulants; Colitis; Cytokines; Dextran Sulfat

2015
Enoxaparin improves the course of dextran sodium sulfate-induced colitis in syndecan-1-deficient mice.
    The American journal of pathology, 2010, Volume: 176, Issue:1

    Topics: Animals; Caco-2 Cells; Cell Adhesion; Cell Proliferation; Colitis; Dextran Sulfate; Enoxaparin; Fibr

2010
Heparin and low-molecular-weight heparin (enoxaparin) significantly ameliorate experimental colitis in rats.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Anticoagulants; Benzenesulfonates; Colitis; Disease Models, Anima

2001