Page last updated: 2024-10-18

dalteparin and Chronic Kidney Failure

dalteparin has been researched along with Chronic Kidney Failure in 69 studies

Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)

Research Excerpts

ExcerptRelevanceReference
"Dalteparin and other low-molecular-weight heparins are frequently used for the treatment of deep vein thrombosis and for other indications."3.73Life-threatening hemorrhage after dalteparin therapy in a patient with impaired renal function. ( Drewe, J; Egger, SS; Krähenbühl, S; Sawatzki, MG, 2005)
"Dalteparin 5,000 IU was administered subcutaneously daily for four consecutive days, with HD performed on day 2 and day 4."2.72A multi-dose pharmacokinetic study of dalteparin in haemodialysis patients. ( Byrne, S; O'Shea, SI; Ortel, TL; Perry, SL; Szczech, LA, 2006)
" The pharmacokinetic model showed that only weight improved the predicted vs observed anti-Xa activity plot."2.71Pharmacokinetics of the low molecular weight heparin enoxaparin during 48 h after bolus administration as an anticoagulant in haemodialysis. ( Berland, Y; Brunet, P; Dussol, B; Guillet, B; Lorec-Penet, AM; Portugal, H; Sampol, JJ; Simon, N, 2003)
"3% of patients no adverse event was reported."2.71Safety and efficacy of single bolus anticoagulation with enoxaparin for chronic hemodialysis. Results of an open-label post-certification study. ( Eckert, M; Hafner, G; Hohmann, V; Klingel, R; Lotz, J; Schwarting, A, 2004)
"Patients with end-stage renal disease (ESRD) suffer from high mortality rates of cardiovascular diseases, conditions closely linked to the magnitude of their chronic low-grade inflammation."2.71Intraperitoneal heparin ameliorates the systemic inflammatory response in PD patients. ( Gram, J; Jespersen, J; Pedersen, RS; Sjøland, JA, 2005)
" SC weight-based dosing on off-dialysis days is a feasible regimen for further clinical thromboprophylaxis efficacy studies in hemodialysis patients."2.70Intravenous and subcutaneous weight-based dosing of the low molecular weight heparin tinzaparin (Innohep) in end-stage renal disease patients undergoing chronic hemodialysis. ( Assaid, CA; Barrett, JS; Cox, DS; Fossler, MJ; Hainer, JW; Hua, TA; Pittenger, AL; Sherrard, DJ; Stephenson, CA; Swan, SK; Williams, RM, 2002)
"Dalteparin was initiated and titrated based on clotting score in these patients."1.56Using dalteparin in quotidian and nocturnal hemodialysis patients: A prospective study. ( Huang, SS; Ke, H; Lindsay, RM; Louzada, M; Muirhead, N; Qi, K; Rehman, F, 2020)
" The risk of under dosing seems less predictable; therefore, anti-Xa assay may be useful in severe clinical situations that require higher anticoagulant activity."1.48Can we reliably predict the level of anticoagulation after enoxaparin injection in elderly patients with renal failure? ( Corrà, L; Di Francesco, V; Facchinetti, R; Fantin, F; Fontana, G; Pellizzari, L; Sepe, A; Zamboni, M, 2018)
"The sVEGFR-1 level of ESRD group was significantly higher (0."1.48Vascular endothelial growth factor and soluble vascular endothelial growth factor receptor-1 in patients with end-stage renal disease. Associations with laboratory findings, comorbidities, and medications. ( Acar, R; Erturk, I; Ozgurtas, T; Saglam, K; Yesildal, F, 2018)
"Dalteparin safety was assessed by monitoring for accumulation, adequate clearance of dalteparin and adverse events."1.48Dalteparin anticoagulation in paediatric home haemodialysis. ( Hothi, DK; Lutkin, M; Stronach, L; Yadav, P, 2018)
"6 IU÷ml was applied, the present dosing method led to over-anticoagulation in more than half of the patients."1.42Anticoagulation with dalteparin and nadroparin in nocturnal haemodialysis. ( van Jaarsveld, BC; Verhave, G; Weijmer, MC, 2015)
" In most patients with end-stage renal disease (ESRD), prophylactic dosage of enoxaparin does not appear to be associated with an increased bleeding risk and can be used without the need for monitoring and adjustment of regimens."1.39Use of enoxaparin in end-stage renal disease. ( Coppola, B; Lai, S, 2013)
"Usually, the appropriate dosage of low-molecular-weight heparin during haemodialysis is empirically based on the clinical effect."1.39Pharmacokinetics of dalteparin during haemodialysis. ( de Groot, KA; Grootendorst, DC; Herruer, MH; Koolen, SL; Nigten, J; Schut, NH, 2013)
" Neither major adverse events nor major hemorrhages were reported Prolonged activated partial thromboplastin times (aPTT) at 30 minutes after hemodialysis were reported in two cases."1.37Efficacy and safety of enoxaparin during hemodialysis: results from the HENOX study. ( Bannachak, D; Chittinandana, A; Kanjanakul, I; Krairittichai, U; Sumethkul, V; Thitiarchakul, S; Vareesangthip, K, 2011)
"Important CKD disagreements occur in approximately 20% of acute coronary syndrome patients, affecting dosing adjustments in those already susceptible to bleeding."1.35Cockcroft-Gault versus modification of diet in renal disease: importance of glomerular filtration rate formula for classification of chronic kidney disease in patients with non-ST-segment elevation acute coronary syndromes. ( Alexander, KP; Chen, AY; Gibler, WB; Harrington, RA; Melloni, C; Newby, LK; Ohman, EM; Peterson, ED; Roe, MT; Spinler, SA; Szczech, LA, 2008)
"Therapeutically dosed dalteparin accumulates in patients with severe RI (group C)."1.35Study of bioaccumulation of dalteparin at a therapeutic dose in patients with renal insufficiency. ( Brodmann, D; Fischer, AG; Odermatt, Y; Schmid, P; Wuillemin, WA, 2009)
"Patients with end-stage renal disease (ESRD) who receive enoxaparin are at increased risk for adverse bleeding episodes."1.33Thrombin generation time is a novel parameter for monitoring enoxaparin therapy in patients with end-stage renal disease. ( Best, AM; Brophy, DF; Carr, ME; Gehr, TW; Martin, EJ; Paul, K, 2006)
" Maximum A Posteriori Bayesian (MAPB) priors were developed by pharmacokinetic analysis."1.33Development of an efficient sampling strategy to predict enoxaparin pharmacokinetics in stage 5 chronic kidney disease. ( Brophy, DF; Overholser, BR; Sowinski, KM, 2006)
"Subjects with ESRD had an approximately 50% greater anticoagulant effect, determined by thrombin generation time prolongation, than controls at antifactor Xa activity concentrations of 0."1.32Enhanced anticoagulant activity of enoxaparin in patients with ESRD as measured by thrombin generation time. ( Brophy, DF; Carr, ME; Gehr, TW; Martin, EJ, 2004)
"Patients with chronic renal failure and hyperphosphatemia may be predisposed to develop calcinosis cutis."1.31Nadroparin-induced Calcinosis cutis in renal transplant recipients. ( Hilbrands, LB; Ruiter, DJ; van Haren, FM, 2001)
"Prospective, single-dose pharmacokinetic study."1.31The pharmacokinetics of subcutaneous enoxaparin in end-stage renal disease. ( Brophy, DF; Comstock, TJ; Gehr, TW; Venitz, J; Wazny, LD, 2001)

Research

Studies (69)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (7.25)18.2507
2000's44 (63.77)29.6817
2010's17 (24.64)24.3611
2020's3 (4.35)2.80

Authors

AuthorsStudies
Verhave, G1
Weijmer, MC1
van Jaarsveld, BC1
Rydzewska-Rosołowska, A1
Borawski, J2
Myśliwiec, M3
Kamper, AM1
Lins, RL1
Zachée, P1
Van Bergen, S1
Hosten, S1
Daelemans, R1
Wanic-Kossowska, M1
Kozioł, L1
Roszkowiak, B1
Lacka, M1
Frankiewicz, D1
Mandel, M1
van Haren, FM1
Ruiter, DJ1
Hilbrands, LB1
Reach, I1
Luong, N1
Chastang, C1
Chakroun, M1
Mirshahi, S1
Mirshahi, MC1
Soria, J1
Desmichels, D1
Baumelou, A1
Batt, TJ1
Lincz, LF1
Prasad, R1
Patel, RP1
Shastri, M1
Lioufas, N1
Smith, AG1
Jose, MD1
Mattioli, M1
Benfaremo, D1
Mancini, M1
Mucci, L1
Mainquà, P1
Polenta, A1
Baldini, PM1
Fulgenzi, F1
Dennetta, D1
Bedetta, S1
Gasperoni, L1
Caraffa, A1
Frausini, G1
Pellizzari, L1
Facchinetti, R1
Corrà, L1
Sepe, A1
Fantin, F1
Fontana, G1
Zamboni, M1
Di Francesco, V1
Erturk, I1
Yesildal, F1
Acar, R1
Ozgurtas, T1
Saglam, K1
Aniort, J1
Piraud, A1
Adda, M1
Perreira, B1
Bouiller, M1
Fourcade, J1
Guerraoui, A1
Kalbacher, E1
Krumel, T1
Moragues, HL1
Thibaudin, D1
Vela, CG1
Vernin, G1
Weclawiak, H1
Bernard, L1
Heng, AE1
Souweine, B1
Chan, KE1
Thadhani, RI1
Maddux, FW1
Naumnik, B3
Koc-Żórawska, E1
Lai, S1
Coppola, B1
Christidou, F1
Bamichas, G1
Galaktidou, G1
Fragidis, S1
Gionanlis, L1
Frangia, T1
Bischiniotis, T1
Sombolos, K1
Saland, JM1
Shneider, BL1
Bromberg, JS1
Shi, PA1
Ward, SC1
Magid, MS1
Benchimol, C1
Seikaly, MG1
Emre, SH1
Bresin, E1
Remuzzi, G1
Albaladejo, P1
Varela Rois, P1
González García, J1
Pérez Rodríguez, MT1
Paseiro García, MJ1
Carcacía Hermilla, ID1
Fernández-Ruiz, M1
Guerra-Vales, JM1
Vega S, J1
Martínez R, G1
Goecke S, H1
Vareesangthip, K1
Thitiarchakul, S1
Kanjanakul, I1
Sumethkul, V1
Krairittichai, U1
Chittinandana, A1
Bannachak, D1
Polkinghorne, KR1
McMahon, LP1
Becker, GJ1
Olszowska, A1
Zelichowski, G1
Lavaud, S1
Canivet, E1
Wuillai, A1
Maheut, H1
Randoux, C1
Bonnet, JM1
Renaux, JL1
Chanard, J1
Guillet, B1
Simon, N1
Sampol, JJ1
Lorec-Penet, AM1
Portugal, H1
Berland, Y1
Dussol, B1
Brunet, P1
Klingel, R2
Schaefer, M1
Schwarting, A2
Himmelsbach, F1
Altes, U1
Uhlenbusch-Körwer, I1
Hafner, G2
Thorevska, N1
Amoateng-Adjepong, Y1
Sabahi, R1
Schiopescu, I1
Salloum, A1
Muralidharan, V1
Manthous, CA1
Brophy, DF7
Martin, EJ4
Gehr, TW5
Carr, ME4
Lotz, J1
Eckert, M1
Hohmann, V1
Best, AM2
Malik, A1
Capling, R1
Bastani, B1
Weinsheimer, RL1
Libby, E1
Howdieshell, TR1
Kruzel-Davila, E1
Frajewicki, V1
Kushnir, D1
Eyal, A1
Kohan, R1
Isla, A1
Gascón, AR1
Maynar, J1
Arzuaga, A1
Corral, E1
Martín, A1
Solinís, MA1
Muñoz, JL1
Paul, K1
Venitz, J2
Overholser, BR1
Sowinski, KM1
Pawlak, K1
Mys'liwiec, M1
Sica, DA1
Melloni, C1
Peterson, ED1
Chen, AY1
Szczech, LA2
Newby, LK1
Harrington, RA1
Gibler, WB1
Ohman, EM1
Spinler, SA1
Roe, MT1
Alexander, KP1
Przedlacki, J1
Bogdańska-Straszyńska, B1
Sawicka, B1
Włodarczyk, D1
Sladowska, B1
Ajewski, M1
Wasiak, K1
Gellert, R1
Wazny, LD1
Comstock, TJ1
Kalus, JS1
Spencer, AP1
Lile, J1
Huang, SS1
Qi, K1
Louzada, M1
Lindsay, RM1
Rehman, F1
Ke, H1
Muirhead, N1
Lutkin, M1
Stronach, L1
Yadav, P1
Hothi, DK1
Nigten, J1
de Groot, KA1
Grootendorst, DC1
Koolen, SL1
Herruer, MH1
Schut, NH1
Nassiri, AA1
Hakemi, MS1
Soulati, M1
Marashian, M1
Rahbar, K1
Azizi, F1
Schmid, P1
Brodmann, D1
Odermatt, Y1
Fischer, AG1
Wuillemin, WA1
Schött, U1
Nilsson, LG1
Broman, M1
Engström, M1
Hiwatashi, A1
Usui, JI1
Sato, C1
Hasegawa, Y1
Yamagata, K1
Rodger, MA1
Ramsay, T1
MacKinnon, M1
Westphal, M1
Wells, PS1
McCormick, B1
Knoll, G1
Egger, SS1
Sawatzki, MG1
Drewe, J1
Krähenbühl, S1
Attman, PO1
Ottosson, P1
Samuelsson, O1
Eriksson, UG1
Eriksson-Lepkowska, M1
Fager, G1
Ziai, F1
Benesch, T1
Kodras, K1
Neumann, I1
Dimopoulos-Xicki, L1
Haas, M1
Gritters, M1
Grooteman, MP1
Schoorl, M2
Bartels, PC1
Scheffer, PG1
Teerlink, T1
Schalkwijk, CG1
Spreeuwenberg, M1
Nubé, MJ1
Kozlova, TV1
Shilo, VIu1
Denisov, AIu1
Perry, SL1
O'Shea, SI1
Byrne, S1
Ortel, TL1
Kerr, PG1
Mattingly, S1
Lo, A1
Atkins, RC1
Hofbauer, R1
Moser, D1
Frass, M1
Oberbauer, R1
Kaye, AD1
Wagner, O1
Kapiotis, S1
Druml, W1
Neuhaus, TJ1
Goetschel, P1
Schmugge, M1
Leumann, E1
Mahmood, D1
Makoveichuk, E1
Nilsson, S1
Olivecrona, G1
Stegmayr, B1
Dhondt, A1
Pauwels, R1
Devreese, K1
Eloot, S1
Glorieux, G1
Vanholder, R1
Hainer, JW1
Sherrard, DJ1
Swan, SK1
Barrett, JS1
Assaid, CA1
Fossler, MJ1
Cox, DS1
Williams, RM1
Pittenger, AL1
Stephenson, CA1
Hua, TA1
Sarris, E1
Tsele, E1
Bagiatoudi, G1
Salpigidis, K1
Stavrianaki, D1
Kaklamanis, L1
Siakotos, M1
Sjøland, JA1
Pedersen, RS1
Jespersen, J1
Gram, J1
Pautas, E1
Siguret, V1
d'Urso, M1
Laurent, M1
Gaussem, P1
Février, M1
Durand-Gasselin, B1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
"Evaluation of the Efficacy of an inTerdialytic Ethanol 40% v/v - enoxapaRin 1000 U/mL Lock solutioN to Prevent Tunnelled Catheter Infections in Chronic Hemodialysis Patients: a mulTi-centre, Randomized, Single Blind, Parallel Group studY (ETERNITY)"[NCT03083184]Phase 3400 participants (Anticipated)Interventional2018-02-09Recruiting
Pilot, Prospective, Multicenter, Open and Non-randomised Study: Definition of an Index of Anti Xa Value at the End of Hemodialysis Treatment.[NCT00781690]53 participants (Actual)Interventional2008-09-30Completed
Study of the Bioaccumulation of Tinzaparin in Renally Impaired Patients When Given at Prophylactic Doses[NCT02719418]28 participants (Actual)Observational2016-02-01Completed
Pharmacokinetics of Dalteparin in Patients With Impaired Renal Function[NCT00264693]96 participants (Actual)Observational2006-01-31Completed
Evaluation of a Simplified Protocol for Regional Citrate Anticoagulation in Continuous Venovenous Hemodiafiltration[NCT00583765]20 participants (Actual)Observational2005-04-30Completed
The Use of Low Molecular Weight Heparin in Hemodiafiltration[NCT00756145]Phase 415 participants (Actual)Interventional2008-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for dalteparin and Chronic Kidney Failure

ArticleYear
[Are low-molecular-weight heparins safe in patients with chronic kidney disease?].
    Revista medica de Chile, 2010, Volume: 138, Issue:4

    Topics: Anticoagulants; Contraindications; Enoxaparin; Heparin, Low-Molecular-Weight; Humans; Kidney Failure

2010
[Enoxaparin in haemodialysis].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2002, Volume: 13, Issue:77

    Topics: Anticoagulants; Enoxaparin; Fibrinolytic Agents; Humans; Kidney Failure, Chronic; Renal Dialysis; Th

2002
Use of enoxaparin in patients with chronic kidney disease: safety considerations.
    Drug safety, 2007, Volume: 30, Issue:11

    Topics: Animals; Anticoagulants; Clinical Trials as Topic; Enoxaparin; Hemorrhage; Humans; Kidney Failure, C

2007

Trials

25 trials available for dalteparin and Chronic Kidney Failure

ArticleYear
Hepatocyte growth factor/activin A/follistatin system activation during hemodialysis with different low molecular weight heparins.
    Renal failure, 2009, Volume: 31, Issue:9

    Topics: Activins; Aged; Cross-Over Studies; Dalteparin; Enoxaparin; Female; Follistatin; Heparin, Low-Molecu

2009
Safety of combining ticlopidine with nadroparin in the routine treatment of chronic hemodialysis patients.
    Nephron, 1997, Volume: 77, Issue:4

    Topics: Drug Combinations; Humans; Kidney Failure, Chronic; Nadroparin; Platelet Aggregation Inhibitors; Ren

1997
Dose effect relationship of reviparin in chronic hemodialysis: a crossover study versus nadroparin.
    Artificial organs, 2001, Volume: 25, Issue:7

    Topics: Aged; Aged, 80 and over; Anticoagulants; Blood Coagulation Tests; Cross-Over Studies; Dose-Response

2001
Evaluation of the efficacy of an interdialytic "ethanol 40% v/v - enoxaparin 1000 U/mL" lock solution to prevent tunnelled catheter infections in chronic hemodialysis patients: a multi-centre, randomized, single blind, parallel group study.
    BMC nephrology, 2019, 04-30, Volume: 20, Issue:1

    Topics: Adult; Anti-Infective Agents, Local; Catheter-Related Infections; Catheters, Indwelling; Clinical Tr

2019
Over-dialysis plasma RANTES increase depends on heparin dose and cardiovascular disease status.
    Advances in medical sciences, 2013, Volume: 58, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Appointments and Schedules; Atherosclerosis; Chemoki

2013
Elevated hepatocyte growth factor levels at the beginning of high-flux hemodialysis are due to heparin administration.
    Renal failure, 2008, Volume: 30, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Cohort Studies; Drug Administration Schedule; Enoxap

2008
Pharmacokinetic studies of dalteparin (Fragmin), enoxaparin (Clexane), and danaparoid sodium (Orgaran) in stable chronic hemodialysis patients.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2002, Volume: 40, Issue:5

    Topics: Anticoagulants; Chondroitin Sulfates; Dalteparin; Dermatan Sulfate; Enoxaparin; Factor Xa Inhibitors

2002
Different effects of enoxaparin and unfractionated heparin on extrinsic blood coagulation during haemodialysis: a prospective study.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2003, Volume: 18, Issue:7

    Topics: Aged; Anticoagulants; Blood Coagulation; Enoxaparin; Female; Fibrinolytic Agents; Follow-Up Studies;

2003
Pharmacokinetics of the low molecular weight heparin enoxaparin during 48 h after bolus administration as an anticoagulant in haemodialysis.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2003, Volume: 18, Issue:11

    Topics: Adult; Aged; Anticoagulants; Enoxaparin; Factor Xa Inhibitors; Female; Humans; Injections, Intraveno

2003
Safety and efficacy of single bolus anticoagulation with enoxaparin for chronic hemodialysis. Results of an open-label post-certification study.
    Kidney & blood pressure research, 2004, Volume: 27, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Enoxaparin; Factor Xa; Female; Humans; Kidney Failur

2004
The pharmacokinetics of enoxaparin do not correlate with its pharmacodynamic effect in patients receiving dialysis therapies.
    Journal of clinical pharmacology, 2006, Volume: 46, Issue:8

    Topics: Adult; Anticoagulants; Blood Coagulation; Drug Monitoring; Enoxaparin; Factor Xa Inhibitors; Female;

2006
Unfractionated heparin but not enoxaparin causes delayed plasma PAI-1 depletion in hemodialysis patients: a prospective study.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2009, Volume: 15, Issue:1

    Topics: Aged; Anticoagulants; E-Selectin; Enoxaparin; Female; Heparin; Humans; Intercellular Adhesion Molecu

2009
[Antithrombotic activity of low molecular weight heparin (enoxaparin) during hemodialysis in patients with terminal kidney failure].
    Polskie Archiwum Medycyny Wewnetrznej, 1994, Volume: 91, Issue:6

    Topics: Adolescent; Adult; Aged; Blood Coagulation Tests; Enoxaparin; Extracorporeal Circulation; Female; He

1994
Effects of heparin and dalteparin on oxidative stress during hemodialysis in patients with end-stage renal disease.
    Iranian journal of kidney diseases, 2009, Volume: 3, Issue:3

    Topics: Adult; Aged; Anticoagulants; Aryldialkylphosphatase; Dalteparin; Drug Costs; Female; Heparin; Humans

2009
Monitoring of low molecular weight heparin anticoagulation during haemodialysis with a Sonoclot Analyzer.
    Perfusion, 2010, Volume: 25, Issue:4

    Topics: Aged; Anticoagulants; Antithrombins; Blood Coagulation; Blood Coagulation Tests; Cross-Over Studies;

2010
Tinzaparin versus dalteparin for periprocedure prophylaxis of thromboembolic events in hemodialysis patients: a randomized trial.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2012, Volume: 60, Issue:3

    Topics: Aged; Aged, 80 and over; Dalteparin; Dose-Response Relationship, Drug; Drug Administration Schedule;

2012
Prevention of clot formation during haemodialysis using the direct thrombin inhibitor melagatran in patients with chronic uraemia.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2005, Volume: 20, Issue:9

    Topics: Adult; Aged; Anticoagulants; Antithrombins; Azetidines; Benzylamines; Chronic Disease; Dalteparin; G

2005
The effect of oral anticoagulation on clotting during hemodialysis.
    Kidney international, 2005, Volume: 68, Issue:2

    Topics: Administration, Oral; Aged; Anticoagulants; Blood Coagulation; Cross-Over Studies; Dalteparin; Drug

2005
Citrate anticoagulation abolishes degranulation of polymorphonuclear cells and platelets and reduces oxidative stress during haemodialysis.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Blood Platelets; Cell Degranulation; Cholesterol, LD

2006
A multi-dose pharmacokinetic study of dalteparin in haemodialysis patients.
    Thrombosis and haemostasis, 2006, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Area Under Curve; Body Weight; Dalteparin; Drug Admi

2006
Effect of anticoagulation on blood membrane interactions during hemodialysis.
    Kidney international, 1999, Volume: 56, Issue:4

    Topics: Adult; Anticoagulants; Blood Coagulation; Cell Adhesion; Citrates; Dalteparin; Erythrocytes; Female;

1999
Where and When To Inject Low Molecular Weight Heparin in Hemodiafiltration? A Cross Over Randomised Trial.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Anticoagulants; beta 2-Microglobulin; Blood Coagulation; Cross-Over Studies; Factor Xa Inhibitors; F

2015
Intravenous and subcutaneous weight-based dosing of the low molecular weight heparin tinzaparin (Innohep) in end-stage renal disease patients undergoing chronic hemodialysis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2002, Volume: 40, Issue:3

    Topics: Adolescent; Adult; Aged; Antithrombin III; Biomarkers; Blood Coagulation; Cross-Over Studies; Dizzin

2002
Intraperitoneal heparin ameliorates the systemic inflammatory response in PD patients.
    Nephron. Clinical practice, 2005, Volume: 100, Issue:4

    Topics: Adult; Aged; C-Reactive Protein; Cross-Over Studies; Double-Blind Method; Female; Fibrin; Fibrin Fib

2005
[Monitoring of tinzaparin in a ten day treatment dose in elderly patients].
    La Revue de medecine interne, 2001, Volume: 22, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Cardiovascular Diseases; Creatinine; Drug Administration Sched

2001

Other Studies

41 other studies available for dalteparin and Chronic Kidney Failure

ArticleYear
Anticoagulation with dalteparin and nadroparin in nocturnal haemodialysis.
    The Netherlands journal of medicine, 2015, Volume: 73, Issue:6

    Topics: Anticoagulants; Blood Coagulation; Dalteparin; Dose-Response Relationship, Drug; Female; Follow-Up S

2015
[Calcified subcutaneous nodules in patients with chronic renal failure as a result of injections with nadroparin (Fraxiparine)].
    Polskie Archiwum Medycyny Wewnetrznej, 1998, Volume: 99, Issue:5

    Topics: Aged; Anticoagulants; Arteriosclerosis; Calcinosis; Female; Humans; Hypertension; Injections, Subcut

1998
Nadroparin-induced Calcinosis cutis in renal transplant recipients.
    Nephron, 2001, Volume: 87, Issue:3

    Topics: Adult; Biopsy; Calcinosis; Calcium; Female; Humans; Kidney Failure, Chronic; Kidney Transplantation;

2001
Plasma levels of enoxaparin oligosaccharides, antifactor-Xa and thrombin generation in patients undergoing haemodialysis.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2020, Volume: 31, Issue:2

    Topics: Adult; Anticoagulants; Enoxaparin; Factor Xa Inhibitors; Humans; Kidney Failure, Chronic; Kinetics;

2020
Safety of intermediate dose of low molecular weight heparin in COVID-19 patients.
    Journal of thrombosis and thrombolysis, 2021, Volume: 51, Issue:2

    Topics: Aged; Aged, 80 and over; COVID-19; COVID-19 Drug Treatment; Enoxaparin; Female; Follow-Up Studies; H

2021
Can we reliably predict the level of anticoagulation after enoxaparin injection in elderly patients with renal failure?
    Aging clinical and experimental research, 2018, Volume: 30, Issue:6

    Topics: Aged; Aged, 80 and over; Anticoagulants; Enoxaparin; Female; Hemorrhage; Heparin, Low-Molecular-Weig

2018
Vascular endothelial growth factor and soluble vascular endothelial growth factor receptor-1 in patients with end-stage renal disease. Associations with laboratory findings, comorbidities, and medications.
    Saudi medical journal, 2018, Volume: 39, Issue:6

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Aspirin; Calcium Channel Blockers; Cardiovascu

2018
No difference in bleeding risk between subcutaneous enoxaparin and heparin for thromboprophylaxis in end-stage renal disease.
    Kidney international, 2013, Volume: 84, Issue:3

    Topics: Aged; Aged, 80 and over; Anticoagulants; Dose-Response Relationship, Drug; Endpoint Determination; E

2013
Use of enoxaparin in end-stage renal disease.
    Kidney international, 2013, Volume: 84, Issue:3

    Topics: Enoxaparin; Female; Hemorrhage; Heparin; Humans; Kidney Failure, Chronic; Male; Venous Thromboemboli

2013
Successful split liver-kidney transplant for factor H associated hemolytic uremic syndrome.
    Clinical journal of the American Society of Nephrology : CJASN, 2009, Volume: 4, Issue:1

    Topics: Anticoagulants; Child, Preschool; Complement Factor H; Enoxaparin; Hemolytic-Uremic Syndrome; Hetero

2009
[Summary and perspectives. Rivaroxaban].
    Annales francaises d'anesthesie et de reanimation, 2008, Volume: 27 Suppl 3

    Topics: Administration, Oral; Aged; Anticoagulants; Clinical Trials, Phase III as Topic; Comorbidity; Enoxap

2008
[Subdural spinal hematoma and intraventricular bleeding after lumbar puncture].
    Revista espanola de anestesiologia y reanimacion, 2009, Volume: 56, Issue:3

    Topics: Aged; Anticoagulants; Back Pain; Cerebral Hemorrhage; Cerebral Ventricles; Enoxaparin; Fatal Outcome

2009
Enoxaparin-induced retroperitoneal haematoma in patients with renal insufficiency.
    Swiss medical weekly, 2010, Feb-20, Volume: 140, Issue:7-8

    Topics: Aged; Aged, 80 and over; Anticoagulants; Enoxaparin; Female; Hematoma; Humans; Kidney Failure, Chron

2010
Efficacy and safety of enoxaparin during hemodialysis: results from the HENOX study.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2011, Volume: 94, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Blood Coagulation Tests; Catheters, Indwelling; Enox

2011
Optimal anticoagulation strategy in haemodialysis with heparin-coated polyacrylonitrile membrane.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2003, Volume: 18, Issue:10

    Topics: Acrylic Resins; Animals; Anticoagulants; Biocompatible Materials; Disease Models, Animal; Dose-Respo

2003
Comparative analysis of procoagulatory activity of haemodialysis, haemofiltration and haemodiafiltration with a polysulfone membrane (APS) and with different modes of enoxaparin anticoagulation.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2004, Volume: 19, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Biocompatible Materials; Blood Coagulation; Blood Co

2004
Anticoagulation in hospitalized patients with renal insufficiency: a comparison of bleeding rates with unfractionated heparin vs enoxaparin.
    Chest, 2004, Volume: 125, Issue:3

    Topics: Aged; Anticoagulants; Enoxaparin; Female; Glomerular Filtration Rate; Hemorrhage; Heparin; Hospitali

2004
Enhanced anticoagulant activity of enoxaparin in patients with ESRD as measured by thrombin generation time.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2004, Volume: 44, Issue:2

    Topics: Adult; Anticoagulants; Blood Coagulation; Blood Coagulation Tests; Chronic Disease; Enoxaparin; Fact

2004
Antifactor Xa activity correlates to thrombin generation time, platelet contractile force and clot elastic modulus following ex vivo enoxaparin exposure in patients with and without renal dysfunction.
    Journal of thrombosis and haemostasis : JTH, 2004, Volume: 2, Issue:8

    Topics: Adult; Anticoagulants; Blood Coagulation Tests; Blood Platelets; Chronic Disease; Dose-Response Rela

2004
Enoxaparin-associated retroperitoneal bleeding in two patients with renal insufficiency.
    Pharmacotherapy, 2005, Volume: 25, Issue:5

    Topics: Aged; Anticoagulants; Enoxaparin; Female; Hematoma; Humans; Kidney Failure, Chronic; Middle Aged; Re

2005
Life-threatening abdominal wall hematoma in a chronic renal failure patient after a single dose of enoxaparin.
    The American surgeon, 2005, Volume: 71, Issue:2

    Topics: Abdominal Injuries; Abdominal Wall; Accidents, Traffic; Adult; Anticoagulants; Enoxaparin; Epigastri

2005
Retroperitoneal hematoma in a hemodialysis patient receiving low molecular weight heparin.
    The Israel Medical Association journal : IMAJ, 2005, Volume: 7, Issue:9

    Topics: Aged; Anticoagulants; Enoxaparin; Female; Hematoma; Humans; Kidney Failure, Chronic; Renal Dialysis;

2005
In vitro and in vivo evaluation of enoxaparin removal by continuous renal replacement therapies with acrylonitrile and polysulfone membranes.
    Clinical therapeutics, 2005, Volume: 27, Issue:9

    Topics: Acrylonitrile; Aged; Aged, 80 and over; Anticoagulants; Enoxaparin; Factor Xa Inhibitors; Female; He

2005
Thrombin generation time is a novel parameter for monitoring enoxaparin therapy in patients with end-stage renal disease.
    Journal of thrombosis and haemostasis : JTH, 2006, Volume: 4, Issue:2

    Topics: Adult; Antithrombin III; Blood Coagulation Tests; Case-Control Studies; Enoxaparin; Female; Fibrinol

2006
Development of an efficient sampling strategy to predict enoxaparin pharmacokinetics in stage 5 chronic kidney disease.
    Therapeutic drug monitoring, 2006, Volume: 28, Issue:6

    Topics: Adult; Antithrombin III; Blood Specimen Collection; Enoxaparin; Female; Humans; Kidney Failure, Chro

2006
Cockcroft-Gault versus modification of diet in renal disease: importance of glomerular filtration rate formula for classification of chronic kidney disease in patients with non-ST-segment elevation acute coronary syndromes.
    Journal of the American College of Cardiology, 2008, Mar-11, Volume: 51, Issue:10

    Topics: Acute Coronary Syndrome; Age Factors; Aged; Creatinine; Enoxaparin; Female; Fibrinolytic Agents; Glo

2008
The pharmacokinetics of subcutaneous enoxaparin in end-stage renal disease.
    Pharmacotherapy, 2001, Volume: 21, Issue:2

    Topics: Adult; Anticoagulants; Area Under Curve; Enoxaparin; Factor Xa; Female; Humans; Injections, Subcutan

2001
Enoxaparin should be used cautiously in patients with end-stage renal disease.
    Pharmacotherapy, 2001, Volume: 21, Issue:8

    Topics: Anticoagulants; Enoxaparin; Humans; Kidney Failure, Chronic; Reproducibility of Results

2001
Low-molecular-weight heparin administration in patients with end-stage renal disease--a comment.
    Pharmacotherapy, 2001, Volume: 21, Issue:8

    Topics: Anticoagulants; Blood Transfusion; Enoxaparin; Hemorrhage; Humans; Kidney Diseases; Kidney Failure,

2001
Using dalteparin in quotidian and nocturnal hemodialysis patients: A prospective study.
    Hemodialysis international. International Symposium on Home Hemodialysis, 2020, Volume: 24, Issue:2

    Topics: Anticoagulants; Dalteparin; Female; Hemodialysis, Home; Humans; Kidney Failure, Chronic; Male; Middl

2020
Dalteparin anticoagulation in paediatric home haemodialysis.
    Pediatric nephrology (Berlin, Germany), 2018, Volume: 33, Issue:12

    Topics: Adolescent; Age Factors; Anticoagulants; Blood Coagulation; Child; Child, Preschool; Dalteparin; Dos

2018
Pharmacokinetics of dalteparin during haemodialysis.
    Nephron. Clinical practice, 2013, Volume: 124, Issue:3-4

    Topics: Aged; Aged, 80 and over; Anticoagulants; Dalteparin; Female; Follow-Up Studies; Humans; Injections,

2013
Study of bioaccumulation of dalteparin at a therapeutic dose in patients with renal insufficiency.
    Journal of thrombosis and haemostasis : JTH, 2009, Volume: 7, Issue:10

    Topics: Aged; Aged, 80 and over; Anticoagulants; Dalteparin; Factor Xa Inhibitors; Female; Glomerular Filtra

2009
Study of bioaccumulation of dalteparin at a therapeutic dose in patients with renal insufficiency.
    Journal of thrombosis and haemostasis : JTH, 2009, Volume: 7, Issue:10

    Topics: Aged; Aged, 80 and over; Anticoagulants; Dalteparin; Factor Xa Inhibitors; Female; Glomerular Filtra

2009
Study of bioaccumulation of dalteparin at a therapeutic dose in patients with renal insufficiency.
    Journal of thrombosis and haemostasis : JTH, 2009, Volume: 7, Issue:10

    Topics: Aged; Aged, 80 and over; Anticoagulants; Dalteparin; Factor Xa Inhibitors; Female; Glomerular Filtra

2009
Study of bioaccumulation of dalteparin at a therapeutic dose in patients with renal insufficiency.
    Journal of thrombosis and haemostasis : JTH, 2009, Volume: 7, Issue:10

    Topics: Aged; Aged, 80 and over; Anticoagulants; Dalteparin; Factor Xa Inhibitors; Female; Glomerular Filtra

2009
Induction of hemodialysis therapy in a case with factor XIII deficiency.
    Clinical and experimental nephrology, 2011, Volume: 15, Issue:5

    Topics: Catheters, Indwelling; Dalteparin; Diabetic Nephropathies; Factor XIII Deficiency; Female; Fibrinoly

2011
Life-threatening hemorrhage after dalteparin therapy in a patient with impaired renal function.
    Pharmacotherapy, 2005, Volume: 25, Issue:6

    Topics: Aged; Aged, 80 and over; Anticoagulants; Dalteparin; Female; Hematoma; Heparin Antagonists; Humans;

2005
[Use of fragmin in program hemodialysis of patients with terminal chronic renal failure].
    Klinicheskaia meditsina, 2005, Volume: 83, Issue:9

    Topics: Adult; Antibodies; Dalteparin; Factor Xa; Female; Fibrinolytic Agents; Humans; Infusion Pumps, Impla

2005
The adequacy of fragmin as a single bolus dose with reused dialyzers.
    Artificial organs, 1994, Volume: 18, Issue:6

    Topics: Adult; Aged; Dalteparin; Equipment Reuse; Hemodialysis Solutions; Heparin; Humans; Kidney Failure, C

1994
Heparin-induced thrombocytopenia type II on hemodialysis: switch to danaparoid.
    Pediatric nephrology (Berlin, Germany), 2000, Volume: 14, Issue:8-9

    Topics: Adolescent; Anticoagulants; Child; Chondroitin Sulfates; Dalteparin; Dermatan Sulfate; Drug Combinat

2000
Response of angiopoietin-like proteins 3 and 4 to hemodialysis.
    The International journal of artificial organs, 2014, Volume: 37, Issue:1

    Topics: Aged; Angiopoietin-Like Protein 1; Angiopoietin-like Proteins; Angiopoietins; Case-Control Studies;

2014
Tinzaparin: excess mortality in elderly patients with renal failure. Unfractionated heparin is best in this setting.
    Prescrire international, 2009, Volume: 18, Issue:103

    Topics: Aged; Aged, 80 and over; Clinical Trials as Topic; Fibrinolytic Agents; Heparin; Heparin, Low-Molecu

2009
Diffuse alopecia in a hemodialysis patient caused by a low-molecular-weight heparin, tinzaparin.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 41, Issue:5

    Topics: Aged; Alopecia; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Humans; Kidney Failure, Chronic;

2003