dalteparin has been researched along with Chemical and Drug Induced Liver Injury in 11 studies
Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intrahepatic bleeding is exceptional and only very few cases have been described." | 1.40 | Fatal intrahepatic hemorrhage after nadroparin use for total hip arthroplasty. ( Bonsignore, A; De Stefano, F; Palmiere, C; Pizzorno, E; Ventura, F, 2014) |
| " A causal relationship between unfractionated heparin and asymptomatic, transient increases in hepatic transaminase levels has been documented; these increased levels also appear to be an underrecognized, adverse effect of LMWH therapy." | 1.31 | Elevation of hepatic transaminases after enoxaparin use: case report and review of unfractionated and low-molecular-weight heparin-induced hepatotoxicity. ( Carlson, MK; Gleason, PP; Sen, S, 2001) |
| " LMWH allows for consistent dosing in postoperative patients without the need for laboratory monitoring." | 1.30 | Intrahepatic hemorrhage after use of low-molecular-weight heparin for total hip arthroplasty. ( Houde, JP; Steinberg, G, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, X | 1 |
| Li, N | 1 |
| Guo, T | 1 |
| Guan, X | 1 |
| Tan, J | 1 |
| Gao, X | 1 |
| Wu, Y | 1 |
| Jia, L | 1 |
| Gu, M | 1 |
| Hua, L | 1 |
| Liu, H | 1 |
| Ventura, F | 1 |
| Bonsignore, A | 1 |
| De Stefano, F | 1 |
| Pizzorno, E | 1 |
| Palmiere, C | 1 |
| Hui, CK | 1 |
| Yuen, MF | 1 |
| Ng, IO | 1 |
| Tsang, KW | 1 |
| Fong, GC | 1 |
| Lai, CL | 1 |
| Nozawa, H | 1 |
| Emoto, S | 1 |
| Sonoda, H | 1 |
| Kawai, K | 1 |
| Sasaki, K | 1 |
| Kaneko, M | 1 |
| Murono, K | 1 |
| Ishii, H | 1 |
| Ishihara, S | 1 |
| Fortea, JI | 1 |
| Zipprich, A | 1 |
| Fernandez-Mena, C | 1 |
| Puerto, M | 1 |
| Bosoi, CR | 1 |
| Almagro, J | 1 |
| Hollenbach, M | 1 |
| Bañares, J | 1 |
| Rodríguez-Sánchez, B | 1 |
| Cercenado, E | 1 |
| Clément, MA | 1 |
| Rose, CF | 1 |
| Bañares, R | 1 |
| Vaquero, J | 1 |
| Ripoll, C | 1 |
| Baker, EL | 1 |
| Loewenthal, T | 1 |
| Salerno, E | 1 |
| Baker, WL | 1 |
| Watkins, PB | 1 |
| Desai, M | 1 |
| Berkowitz, SD | 1 |
| Peters, G | 1 |
| Horsmans, Y | 1 |
| Larrey, D | 1 |
| Maddrey, W | 1 |
| Houde, JP | 1 |
| Steinberg, G | 1 |
| Carlson, MK | 1 |
| Gleason, PP | 1 |
| Sen, S | 1 |
| Levinson, P | 1 |
| Glaumann, H | 1 |
| Söderberg, M | 1 |
| Valois, M | 1 |
| Cooper, MA | 1 |
| Shear, NH | 1 |
1 trial available for dalteparin and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Evaluation of drug-induced serious hepatotoxicity (eDISH): application of this data organization approach to phase III clinical trials of rivaroxaban after total hip or knee replacement surgery.
Topics: Adverse Drug Reaction Reporting Systems; Aged; Alanine Transaminase; Alkaline Phosphatase; Arthropla | 2011 |
10 other studies available for dalteparin and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Comparison of the Effects of Low-Molecular-Weight Heparin and Fondaparinux on Liver Function in Patients With Pulmonary Embolism.
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Asian People; Chemical and Drug Induced Liver Injury | 2020 |
Fatal intrahepatic hemorrhage after nadroparin use for total hip arthroplasty.
Topics: Aged; Anticoagulants; Arthroplasty, Replacement, Hip; Autopsy; Cause of Death; Chemical and Drug Ind | 2014 |
Low molecular weight heparin-induced liver toxicity.
Topics: Adult; Anticoagulants; Cerebral Infarction; Chemical and Drug Induced Liver Injury; Complement C3; E | 2001 |
Liver Injury Among Japanese Patients Treated Using Prophylactic Enoxaparin After Colorectal Surgery.
Topics: Anticoagulants; Asian People; Case-Control Studies; Chemical and Drug Induced Liver Injury; Colorect | 2021 |
Enoxaparin does not ameliorate liver fibrosis or portal hypertension in rats with advanced cirrhosis.
Topics: Animals; Anticoagulants; Bacterial Translocation; Biomarkers; Blood Coagulation; Chemical and Drug I | 2018 |
Probable enoxaparin-induced hepatotoxicity.
Topics: Adult; Anticoagulants; Chemical and Drug Induced Liver Injury; Enoxaparin; Female; Humans; Injection | 2009 |
Intrahepatic hemorrhage after use of low-molecular-weight heparin for total hip arthroplasty.
Topics: Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Chemical and Drug Induced Liver Injury; Eno | 1999 |
Elevation of hepatic transaminases after enoxaparin use: case report and review of unfractionated and low-molecular-weight heparin-induced hepatotoxicity.
Topics: Aged; Alanine Transaminase; Alkaline Phosphatase; Anticoagulants; Aspartate Aminotransferases; Chemi | 2001 |
Probable dalteparin-induced hepatotoxicity in a man with alpha-1-antitrypsin deficiency.
Topics: alpha 1-Antitrypsin Deficiency; Anticoagulants; Chemical and Drug Induced Liver Injury; Cholestasis; | 2012 |
Clinical pharmacology consultations: consultation requests may be misleading -- an organized approach to drug-induced hepatitis.
Topics: Adverse Drug Reaction Reporting Systems; Chemical and Drug Induced Liver Injury; Dalteparin; Diagnos | 2003 |