Page last updated: 2024-10-18

dalteparin and Cerebral Infarction

dalteparin has been researched along with Cerebral Infarction in 18 studies

Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)

Cerebral Infarction: The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).

Research Excerpts

ExcerptRelevanceReference
"The analyses used data from the Tinzapararin in Acute Ischaemic Stroke Trial, a randomized controlled trial assessing tinzaparin (low molecular weight heparin) versus aspirin in 1484 patients with acute ischemic stroke."5.14Asymptomatic hemorrhagic transformation of infarction and its relationship with functional outcome and stroke subtype: assessment from the Tinzaparin in Acute Ischaemic Stroke Trial. ( Bath, PM; Christensen, H; De Deyn, P; England, TJ; Geeganage, C; Leys, D; Moulin, T; O'Neill, D; Ringelstein, EB; Sare, GM; Woimant, F, 2010)
" We report a 22 year-old male with ulcerative colitis in treatment with mesalazine and prednisone presenting with headache and speech disturbances."3.81[Intracranial sinus venous thrombosis in ulcerative colitis. Report of one case]. ( Bagattini, JC; Calcagno, GP; Chiarella, M; Cohen, H; Forster, TA, 2015)
"After undergoing surgery for a ruptured aneurysm, 170 patients were randomized in a prospective, double-blind, placebo-controlled trial to test the effect of enoxaparin on the occurrence of ischemic lesions, which were demonstrated on follow-up CT scans available for 156 patients."2.71Risk factors for ischemic lesions following aneurysmal subarachnoid hemorrhage. ( Juvela, S; Porras, M; Poussa, K; Siironen, J; Varis, J, 2005)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.56)18.2507
2000's8 (44.44)29.6817
2010's4 (22.22)24.3611
2020's5 (27.78)2.80

Authors

AuthorsStudies
Brüggemann, R1
Gietema, H1
Jallah, B1
Ten Cate, H1
Stehouwer, C1
Spaetgens, B1
Kay, R1
Wong, KS1
Yu, YL1
Chan, YW1
Tsoi, TH1
Ahuja, AT1
Chan, FL1
Fong, KY1
Law, CB1
Wong, A1
Hui, CK1
Yuen, MF1
Ng, IO1
Tsang, KW1
Fong, GC1
Lai, CL1
Yasutaka, Y1
Fujioka, S1
Tsuboi, Y1
Oyabu, K1
Shibaguchi, H1
Kamimura, H1
Alay, H1
Can, FK1
Gözgeç, E1
Gao, M1
Lei, J1
Patel, S1
Sanborn, D1
Issa, M1
Calcagno, GP1
Bagattini, JC1
Forster, TA1
Chiarella, M1
Cohen, H1
Fraint, E1
Miller, R1
Walter, A1
Listernick, R1
Wurm, G1
Tomancok, B1
Nussbaumer, K1
Adelwöhrer, C1
Holl, K1
Vilkki, JS1
Juvela, S2
Siironen, J2
Ilvonen, T1
Varis, J2
Porras, M2
Poussa, K1
Quartermain, D2
Li, Y1
Jonas, S2
Diener, HC1
England, TJ1
Bath, PM2
Sare, GM1
Geeganage, C1
Moulin, T1
O'Neill, D2
Woimant, F1
Christensen, H1
De Deyn, P1
Leys, D2
Ringelstein, EB1
Gray, LJ1
Sprigg, N1
Sørensen, P1
Lindenstrøm, E1
Boysen, G1
De Deyn, PP1
Friis, P1
Marttila, R1
Olsson, JE1
Ringelstein, B1
van der Sande, JJ1
Turpie, AG1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Improving Outcome in Subarachnoid Hemorrhage wIth Nadroparine[NCT04507178]Phase 2100 participants (Anticipated)Interventional2022-02-02Recruiting
Pilot Study of Treatment With Intravenous Enoxaparin and/or Oral Minocycline to Limit Infarct Size After Ischemic Stroke[NCT00836355]6 participants (Actual)Interventional2009-04-30Terminated (stopped due to Too few acute stroke patients available to meet enrollment requirements.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for dalteparin and Cerebral Infarction

ArticleYear
Low molecular weight heparin and the treatment of ischemic stroke. Animal results, the reasons for failure in human stroke trials, mechanisms of action, and the possibilities for future use in stroke.
    Annals of the New York Academy of Sciences, 2001, Volume: 939

    Topics: Animals; Anticoagulants; Calcium; Calcium Channel Blockers; Cerebral Infarction; Clinical Trials as

2001

Trials

6 trials available for dalteparin and Cerebral Infarction

ArticleYear
Low-molecular-weight heparin for the treatment of acute ischemic stroke.
    The New England journal of medicine, 1995, Dec-14, Volume: 333, Issue:24

    Topics: Activities of Daily Living; Acute Disease; Aged; Brain Ischemia; Cerebral Hemorrhage; Cerebral Infar

1995
Reduction of ischemic sequelae following spontaneous subarachnoid hemorrhage: a double-blind, randomized comparison of enoxaparin versus placebo.
    Clinical neurology and neurosurgery, 2004, Volume: 106, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Brain Ischemia; Cerebral Infarction; Double-Blind Me

2004
Relationship of local infarctions to cognitive and psychosocial impairments after aneurysmal subarachnoid hemorrhage.
    Neurosurgery, 2004, Volume: 55, Issue:4

    Topics: Cerebral Infarction; Double-Blind Method; Enoxaparin; Female; Humans; Male; Middle Aged; Neuropsycho

2004
Risk factors for ischemic lesions following aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 2005, Volume: 102, Issue:2

    Topics: Adult; Aged; Aneurysm, Ruptured; Anticoagulants; Cerebral Infarction; Double-Blind Method; Enoxapari

2005
Asymptomatic hemorrhagic transformation of infarction and its relationship with functional outcome and stroke subtype: assessment from the Tinzaparin in Acute Ischaemic Stroke Trial.
    Stroke, 2010, Volume: 41, Issue:12

    Topics: Aged; Anticoagulants; Aspirin; Cerebral Hemorrhage; Cerebral Infarction; Dose-Response Relationship,

2010
Significant variation in mortality and functional outcome after acute ischaemic stroke between Western countries: data from the tinzaparin in acute ischaemic stroke trial (TAIST).
    Journal of neurology, neurosurgery, and psychiatry, 2006, Volume: 77, Issue:3

    Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Cause of Death; Cerebral Infarction; Cro

2006

Other Studies

11 other studies available for dalteparin and Cerebral Infarction

ArticleYear
Arterial and venous thromboembolic disease in a patient with COVID-19: A case report.
    Thrombosis research, 2020, Volume: 191

    Topics: Anticoagulants; Cerebral Infarction; Clopidogrel; Computed Tomography Angiography; Coronavirus Infec

2020
Low molecular weight heparin-induced liver toxicity.
    Journal of clinical pharmacology, 2001, Volume: 41, Issue:6

    Topics: Adult; Anticoagulants; Cerebral Infarction; Chemical and Drug Induced Liver Injury; Complement C3; E

2001
Liver toxicity of intravenous heparin treatment in patients with acute ischemic stroke.
    Clinical neurology and neurosurgery, 2023, Volume: 226

    Topics: Anticoagulants; Cerebral Infarction; Edaravone; Enoxaparin; Heparin; Humans; Ischemic Stroke; Liver;

2023
Cerebral Infarction in an Elderly Patient with Coronavirus Disease.
    Revista da Sociedade Brasileira de Medicina Tropical, 2020, Volume: 53

    Topics: Aged, 80 and over; Anticoagulants; Aspirin; Betacoronavirus; Cerebral Infarction; Coronavirus; Coron

2020
Image and clinical analysis of common carotid web: a case report.
    BMC medical imaging, 2021, 01-06, Volume: 21, Issue:1

    Topics: Aged; Anticoagulants; Aspirin; Basal Ganglia Diseases; Carotid Artery Diseases; Carotid Artery, Comm

2021
57-Year-Old Woman With Weakness and Word-Finding Difficulties.
    Mayo Clinic proceedings, 2021, Volume: 96, Issue:2

    Topics: Adenocarcinoma, Clear Cell; Antibodies, Antiphospholipid; Aspirin; Biomarkers, Tumor; Cerebral Infar

2021
[Intracranial sinus venous thrombosis in ulcerative colitis. Report of one case].
    Revista medica de Chile, 2015, Volume: 143, Issue:4

    Topics: Anti-Inflammatory Agents; Anticoagulants; Cerebral Infarction; Colitis, Ulcerative; Enoxaparin; Head

2015
Posterior Reversible Encephalopathy Syndrome and Cerebral Sinus Thrombosis in a Case of Pediatric B-Cell ALL.
    Journal of pediatric hematology/oncology, 2017, Volume: 39, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Ischemia; Cerebral Infarction; Child, Preschoo

2017
A 15-year-old girl with hypertension.
    Pediatric annals, 2011, Volume: 40, Issue:5

    Topics: Adolescent; Anticoagulants; Antiphospholipid Syndrome; Cerebral Infarction; Enoxaparin; Female; Huma

2011
Enoxaparin, a low molecular weight heparin decreases infarct size and improves sensorimotor function in a rat model of focal cerebral ischemia.
    Neuroscience letters, 2000, Jul-14, Volume: 288, Issue:2

    Topics: Animals; Brain Ischemia; Cerebral Infarction; Enoxaparin; Injections, Subcutaneous; Male; Motor Acti

2000
[Initial results of the PROTECT Study publicized. Stroke patients need effective thrombosis prevention].
    MMW Fortschritte der Medizin, 2005, Jun-02, Volume: 147, Issue:22

    Topics: Anticoagulants; Cerebral Infarction; Double-Blind Method; Hemorrhage; Heparin; Heparin, Low-Molecula

2005