Page last updated: 2024-10-18

dalteparin and Cardiovascular Diseases

dalteparin has been researched along with Cardiovascular Diseases in 29 studies

Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)

Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.

Research Excerpts

ExcerptRelevanceReference
" In this randomized, open-label, multicenter trial, we compared aspirin (ASA) or fixed low-dose warfarin (WAR) versus low molecular weight heparin (LMWH) for preventing thromboembolism in patients with myeloma treated with thalidomide-based regimens."9.15Aspirin, warfarin, or enoxaparin thromboprophylaxis in patients with multiple myeloma treated with thalidomide: a phase III, open-label, randomized trial. ( Baldini, L; Benevolo, G; Boccadoro, M; Bringhen, S; Callea, V; Caravita, T; Carella, AM; Cavo, M; Cellini, C; Crippa, C; Elice, F; Evangelista, A; Galli, M; Gentilini, F; Magarotto, V; Marasca, R; Montefusco, V; Morabito, F; Nozzoli, C; Offidani, M; Palumbo, A; Patriarca, F; Pescosta, N; Polloni, C; Pulini, S; Ria, R; Romano, A; Rossi, D; Tacchetti, P; Tosi, P; Zamagni, E; Zambello, R, 2011)
"Among hospitalized medically ill patients, extended-duration betrixaban demonstrated an ≈30% reduction in fatal or irreversible ischemic or bleeding events compared with standard-duration enoxaparin."5.24Comparison of Fatal or Irreversible Events With Extended-Duration Betrixaban Versus Standard Dose Enoxaparin in Acutely Ill Medical Patients: An APEX Trial Substudy. ( Arbetter, D; Chi, G; Cohen, AT; Daaboul, Y; Gibson, CM; Gold, A; Goldhaber, SZ; Harrington, RA; Hernandez, AF; Hull, R; Jain, P; Korjian, S; Lopes, RD, 2017)
" In this randomized, open-label, multicenter trial, we compared aspirin (ASA) or fixed low-dose warfarin (WAR) versus low molecular weight heparin (LMWH) for preventing thromboembolism in patients with myeloma treated with thalidomide-based regimens."5.15Aspirin, warfarin, or enoxaparin thromboprophylaxis in patients with multiple myeloma treated with thalidomide: a phase III, open-label, randomized trial. ( Baldini, L; Benevolo, G; Boccadoro, M; Bringhen, S; Callea, V; Caravita, T; Carella, AM; Cavo, M; Cellini, C; Crippa, C; Elice, F; Evangelista, A; Galli, M; Gentilini, F; Magarotto, V; Marasca, R; Montefusco, V; Morabito, F; Nozzoli, C; Offidani, M; Palumbo, A; Patriarca, F; Pescosta, N; Polloni, C; Pulini, S; Ria, R; Romano, A; Rossi, D; Tacchetti, P; Tosi, P; Zamagni, E; Zambello, R, 2011)
"Enoxaparin is noninferior to UFH+phenprocoumon for prevention of ischemic and embolic events, bleeding complications, and death in TEE-guided cardioversion of atrial fibrillation."5.11Safety and efficacy of enoxaparin compared with unfractionated heparin and oral anticoagulants for prevention of thromboembolic complications in cardioversion of nonvalvular atrial fibrillation: the Anticoagulation in Cardioversion using Enoxaparin (ACE) ( Daniel, WG; Geller, C; Hanrath, P; Hofmann, T; Lehmacher, W; Mügge, A; Nixdorff, U; Schmidt-Lucke, C; Schmidt-Lucke, JA; Sehnert, W; Stellbrink, C, 2004)
"(1) Aspirin reduces acute-phase mortality after myocardial infarction, and also reduces the risk of myocardial infarction and death in patients with unstable angina."3.70Antiplatelet drugs in cardiovascular prevention: coronary events: acute phase and secondary prevention. ( , 2000)
"Bleeding was predominantly gastrointestinal or intracranial."2.82Andexanet Alfa for Acute Major Bleeding Associated with Factor Xa Inhibitors. ( Albaladejo, P; Beyer-Westendorf, J; Bronson, MD; Cohen, AT; Conley, PB; Connolly, SJ; Crowther, M; Curnutte, JT; Eikelboom, JW; Gibson, CM; Gold, A; Goodman, S; Leeds, J; Lim, WT; Lopez-Sendon, J; Lu, G; Meeks, B; Middeldorp, S; Milling, TJ; Nakamya, J; Schmidt, J; Siegal, DM; Verhamme, P; Wiens, BL; Zotova, E, 2016)
"Enoxaparin dosage for obese patients and patients with renal impairment remains controversial."2.71Dosage of enoxaparin among obese and renal impairment patients. ( Almanric, K; Bazinet, A; Blais, N; Brunet, C; Caron, S; Lalonde, L; Martineau, J; Turcotte, I, 2005)
"Dabigatran etexilate is an oral direct thrombin inhibitor that has been approved by the US Food and Drug Administration for the prevention of stroke and systemic embolization in patients with nonvalvular atrial fibrillation."2.47Hospital-based clinical implications of the novel oral anticoagulant, dabigatran etexilate, in daily practice. ( Pendleton, RC; Rodgers, GM; Smock, KJ; Wilcox, R, 2011)
"This study aimed to estimate how prevalent potential drug-drug interactions (pDDIs) were in patients with cardiovascular diseases who were hospitalized for more than 24 hours, and to determine the risk factors associated with these pDDIs."1.91Detection and analysis of potential drug-drug interactions among patients admitted to the cardiac care unit in a tertiary care hospital. ( Almaghaslah, D; Khaled, A; Makki, S; Nagib, R; Siddiqua, A, 2023)
"The sVEGFR-1 level of ESRD group was significantly higher (0."1.48Vascular endothelial growth factor and soluble vascular endothelial growth factor receptor-1 in patients with end-stage renal disease. Associations with laboratory findings, comorbidities, and medications. ( Acar, R; Erturk, I; Ozgurtas, T; Saglam, K; Yesildal, F, 2018)
"Dabigatran has demonstrated similar efficacy and safety to enoxaparin for VTE prevention in patients undergoing hip and knee arthroplasty, and to warfarin for the treatment of VTE."1.42The evolving role of dabigatran etexilate in clinical practice. ( Drambarean, B; Hellenbart, E; Lee, J; Nutescu, EA, 2015)
"Rectus sheath hematoma is an uncommon cause of acute abdomen and is known to mimic various common surgical conditions."1.33Massive rectus sheath hematoma. ( Hamdan, K; Rajagopal, AS; Shinkfield, M; Voight, S, 2006)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.45)18.7374
1990's2 (6.90)18.2507
2000's14 (48.28)29.6817
2010's9 (31.03)24.3611
2020's3 (10.34)2.80

Authors

AuthorsStudies
Sirenko, IuN1
Sychev, OS1
Reĭko, MN1
Shchupak, MB1
Sidorenko, PI1
Camporese, G1
Bernardi, E1
Noventa, F1
McKeage, K1
Keating, GM1
Voci, D3
Götschi, A3
Held, U3
Bingisser, R3
Colucci, G3
Duerschmied, D3
Fumagalli, RM3
Gerber, B3
Hasse, B3
Keller, DI3
Konstantinides, SV3
Mach, F3
Rampini, SK3
Righini, M3
Robert-Ebadi, H3
Rosemann, T3
Roth-Zetzsche, S3
Sebastian, T3
Simon, NR3
Spirk, D3
Stortecky, S3
Vaisnora, L3
Kucher, N3
Barco, S3
Khaled, A1
Almaghaslah, D1
Nagib, R1
Makki, S1
Siddiqua, A1
Boari, GEM1
Chiarini, G1
Bonetti, S1
Malerba, P1
Bianco, G1
Faustini, C1
Braglia-Orlandini, F1
Turini, D1
Guarinoni, V1
Saottini, M1
Viola, S1
Ferrari-Toninelli, G1
Pasini, G1
Mascadri, C1
Bonzi, B1
Desenzani, P1
Tusi, C1
Zanotti, E1
Nardin, M1
Rizzoni, D1
Gibson, CM2
Korjian, S1
Chi, G1
Daaboul, Y1
Jain, P1
Arbetter, D1
Goldhaber, SZ1
Hull, R1
Hernandez, AF1
Lopes, RD1
Gold, A2
Cohen, AT2
Harrington, RA1
Erturk, I1
Yesildal, F1
Acar, R1
Ozgurtas, T1
Saglam, K1
Hellenbart, E1
Drambarean, B1
Lee, J1
Nutescu, EA1
Connolly, SJ1
Milling, TJ1
Eikelboom, JW1
Curnutte, JT1
Bronson, MD1
Lu, G1
Conley, PB1
Verhamme, P1
Schmidt, J1
Middeldorp, S1
Beyer-Westendorf, J1
Albaladejo, P1
Lopez-Sendon, J1
Goodman, S1
Leeds, J1
Wiens, BL1
Siegal, DM1
Zotova, E1
Meeks, B1
Nakamya, J1
Lim, WT1
Crowther, M1
Khoobiar, S1
Mejevoi, N1
Kaid, K1
Boiangiu, C1
Setty, S1
Tanwir, A1
Khalid, K1
Cohen, M1
Zeymer, U1
Gitt, A1
Zahn, R1
Jünger, C1
Bauer, T1
Heer, T1
Koeth, O1
Senges, J1
Palumbo, A1
Cavo, M1
Bringhen, S1
Zamagni, E1
Romano, A1
Patriarca, F1
Rossi, D1
Gentilini, F1
Crippa, C1
Galli, M1
Nozzoli, C1
Ria, R1
Marasca, R1
Montefusco, V1
Baldini, L1
Elice, F1
Callea, V1
Pulini, S1
Carella, AM1
Zambello, R1
Benevolo, G1
Magarotto, V1
Tacchetti, P1
Pescosta, N1
Cellini, C1
Polloni, C1
Evangelista, A1
Caravita, T1
Morabito, F1
Offidani, M1
Tosi, P1
Boccadoro, M1
Wilcox, R1
Pendleton, RC1
Smock, KJ1
Rodgers, GM1
Hoffmann, P1
Keller, F1
Katrancioglu, N1
Karahan, O1
Kilic, AT1
Altun, A1
Katrancioglu, O1
Polat, ZA1
Biteker, M1
Tekkeşin, Aİ1
Can, MM1
Dayan, A1
Ilhan, E1
Türkmen, FM1
Bergmann, JF1
Mouly, S1
Chow, SL1
Zammit, K1
West, K1
Dannenhoffer, M1
Lopez-Candales, A1
Stellbrink, C1
Nixdorff, U1
Hofmann, T1
Lehmacher, W1
Daniel, WG1
Hanrath, P1
Geller, C1
Mügge, A1
Sehnert, W1
Schmidt-Lucke, C1
Schmidt-Lucke, JA1
Chazova, IE1
Mychka, VB1
Mamyrbaeva, KM1
Gornostaev, VV1
Dvoskina, IM1
Sergienko, VB1
Bazinet, A1
Almanric, K1
Brunet, C1
Turcotte, I1
Martineau, J1
Caron, S1
Blais, N1
Lalonde, L1
Spinler, S1
Rajagopal, AS1
Shinkfield, M1
Voight, S1
Hamdan, K1
Le Feuvre, C1
Batisse, A1
Collet, JP1
Batisse, JP1
Choussat, R1
Beygui, F1
Helft, G1
Montalescot, G1
Metzger, JP1
Hunt, D1
SUSSMAN, I1
LYDECKER, E1
Pautas, E1
Siguret, V1
d'Urso, M1
Laurent, M1
Gaussem, P1
Février, M1
Durand-Gasselin, B1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
(Apex) Multicenter, Randomized, Active-Controlled Efficacy And Safety Study Comparing Extended Duration Betrixaban With Standard Of Care Enoxaparin For The Prevention Of Venous Thromboembolism In Acute Medically Ill Patients[NCT01583218]Phase 37,513 participants (Actual)Interventional2012-03-31Completed
Optimal Delay Time to Initiate Anticoagulation After Ischemic Stroke in Atrial Fibrillation[NCT03021928]Phase 3200 participants (Actual)Interventional2017-06-14Active, not recruiting
Prospective, Open-Label Study of Andexanet Alfa in Patients Receiving a Factor Xa Inhibitor Who Have Acute Major Bleeding (ANNEXA-4)[NCT02329327]Phase 3479 participants (Actual)Interventional2015-04-10Completed
Thrombosis in Newly Diagnosed Multiple Myeloma Patients: a Clinical Audit of Intermediate Dose Low Molecular Weight Heparin[NCT05541978]140 participants (Actual)Observational2022-09-01Completed
Evaluation of the Use of an Oral Direct Anti-Xa Anticoagulant, Apixaban, in Prevention of Venous Thromboembolic Disease in Patients Treated With IMiDs During Myeloma : a Pilot Study[NCT02066454]Phase 3105 participants (Anticipated)Interventional2014-04-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

mITT Cohort 1: Percentage of Participants Experiencing the Composite Event of Symptomatic DVT, Non-fatal PE, or VTE-related Death, Through Visit 3

mITT Cohort 1: Percentage of participants experiencing either symptomatic DVT, non-fatal PE, or VTE related death adjudicated by a blinded independent CEC between randomization and on or before Visit 3 or Day 42 if patient did not have a Visit 3. Visit 3 is between day 35-42 after randomization (day 1). (NCT01583218)
Timeframe: mITT Cohort 1: Between randomization and Day 42 (max)

InterventionPercentage of Participants (Number)
Betrixaban1.30
Enoxaparin1.90

mITT Cohort 2: Percentage of Participants Experiencing the Composite Event of Symptomatic DVT, Non-fatal PE, or VTE-related Death, Through Visit 3

mITT Cohort 2: Percentage of participants experiencing either symptomatic DVT, non-fatal PE, or VTE related death adjudicated by a blinded independent CEC between randomization and on or before Visit 3 or Day 42 if patient did not have a Visit 3. Visit 3 is between day 35-42 after randomization (day 1). (NCT01583218)
Timeframe: mITT Cohort 2: Between randomization and Day 42 (max)

InterventionPercentage of Participants (Number)
Betrixaban1.03
Enoxaparin1.45

mITT Cohort 2: Percentage of Participants Experiencing the Composite Event of Symptomatic DVT, Non-fatal PE, VTE-related Death, or Asymptomatic Proximal DVT, Through Visit 3

mITT Cohort 2: Percentage of participants experiencing either symptomatic DVT, non-fatal PE, VTE related death adjudicated by a blinded independent CEC between randomization and on or before Visit 3 or Day 42 if patient did not have a Visit 3, or a blinded ultrasound core laboratory measuring of asymptomatic proximal DVT between randomization and Day 47. Visit 3 is between day 35-42 after randomization (day 1). (NCT01583218)
Timeframe: mITT Cohort 2: Between randomization and Day 47 (max)

InterventionPercentage of Participants (Number)
Betrixaban4.70
Enoxaparin6.02

mITT: Percentage of Participants Experiencing the Composite Event of Symptomatic DVT, Non-fatal PE, or VTE-related Death, Through Visit 3

mITT: Percentage of participants experiencing either symptomatic DVT, non-fatal PE, or VTE related death adjudicated by a blinded independent CEC between randomization and on or before Visit 3 or Day 42 if patient did not have a Visit 3. Visit 3 is between day 35-42 after randomization (day 1). (NCT01583218)
Timeframe: mITT: Between randomization and Day 42 (max)

InterventionPercentage of Participants (Number)
Betrixaban0.94
Enoxaparin1.45

mITT: Percentage of Participants Experiencing the Composite Event of Symptomatic DVT, Non-fatal PE, VTE-related Death, or Asymptomatic Proximal DVT, Through Visit 3

mITT: Percentage of participants experiencing either symptomatic DVT, non-fatal PE, VTE related death adjudicated by a blinded independent CEC between randomization and on or before Visit 3 or Day 42 if patient did not have a Visit 3, or a blinded ultrasound core laboratory measuring of asymptomatic proximal DVT between randomization and Day 47. Visit 3 is between day 35-42 after randomization (day 1). (NCT01583218)
Timeframe: mITT: Between randomization and Day 47 (max)

InterventionPercentage of Participants (Number)
Betrixaban4.43
Enoxaparin5.99

Modified Intent-to-Treat (mITT) Cohort 1: Percentage of Participants Experiencing the Composite Event of Symptomatic Deep Vein Thrombosis (DVT), Non-fatal Pulmonary Emboli (PE), VTE-related Death, or Asymptomatic Proximal DVT, Through Visit 3

mITT Cohort 1: Percentage of participants experiencing either symptomatic DVT, non-fatal PE, venous thromboembolism (VTE) related death adjudicated by a blinded independent Clinical Events Committee (CEC) between randomization and on or before Visit 3 or Day 42 if patient did not have a Visit 3, or a blinded ultrasound core laboratory measuring of asymptomatic proximal DVT between randomization and Day 47. Visit 3 is between day 35-42 after randomization (day 1). (NCT01583218)
Timeframe: mITT Cohort 1: Between randomization and Day 47 (max)

InterventionPercentage of Participants (Number)
Betrixaban5.70
Enoxaparin7.18

Percentage of Participants Experiencing Major Bleeding Through Seven Days After Discontinuation of All Study Medication

Percentage of participants experiencing at least one major bleeding adjudicated by a blinded independent CEC between randomization (day 1) and up to seven days after discontinuation of all study medication. (NCT01583218)
Timeframe: Between randomization and Day 49 (max)

InterventionPercentage of Participants (Number)
Betrixaban0.67
Enoxaparin0.57

Percent Change From Baseline In Anti-fXa Activity By FXa Inhibitor

Anti-fXa activity was measured to assess the ability of andexanet to reverse the anticoagulant effect of FXa inhibitors. Baseline was defined as the last value obtained prior to the start of the andexanet bolus. The change from baseline was calculated as the reduction in anti-fXa activity from baseline to the on-treatment nadir (that is, the minimum value between end of bolus and end of infusion). Percent reduction was calculated as the ratio between the maximum change from baseline and the baseline value, multiplied by 100. (NCT02329327)
Timeframe: Baseline, 12 Hours (post infusion)

InterventionPercent Change (Median)
FXa Inhibitor: Apixaban-93.3
FXa Inhibitor: Rivaroxaban-94.1
FXa Inhibitor: Edoxaban-71.3
FXa Inhibitor: Enoxaparin-75.41
FXa Inhibitor: Rivaroxaban - Additional Participants-96.3

Participants Achieving Hemostatic Efficacy

Hemostatic efficacy was achieved when the body had time to produce thrombin and a subsequent clot and was rated by the EAC as: excellent; good; poor/none; not evaluable due to non-administrative reasons; not evaluable due to administrative reasons. These ratings were based on pre-specified criteria that were included in the EAC Charter. The EAC was blinded to anti-fXa activity levels. Participant results were classified as either success or failure based on the hemostatic efficacy rating (success = excellent/good, failure = poor/none). Participants rated by the EAC as non-evaluable due to administrative reasons were excluded from the analysis of hemostatic efficacy. (NCT02329327)
Timeframe: 12 Hours (post infusion)

,,,,,,,,,,,,,
InterventionParticipants (Count of Participants)
Excellent/GoodPoor/None
Andexanet: High Dose5417
Andexanet: High Dose - Additional Participant10
Andexanet: Low Dose21851
Andexanet: Low Dose - Additional Participant10
Bleed Type: Gastrointestinal6113
Bleed Type: Intracranial Hemorrhage19351
Bleed Type: Intracranial Hemorrhage - Additional Participants20
Bleed Type: Other184
FXa Inhibitor: Apixaban13435
FXa Inhibitor: Edoxaban226
FXa Inhibitor: Enoxaparin142
FXa Inhibitor: Rivaroxaban10225
FXa Inhibitor: Rivaroxaban - Additional Participants20
Overall27268

Percent Change From Baseline In Anti-fXa Activity By Hemostatic Efficacy

This outcome measure assessed the relationship between hemostatic efficacy and anti-fXa activity in participants receiving an FXa inhibitor who had acute major bleeding. Anti-fXa activity was measured to assess the ability of andexanet to reverse the anticoagulant effect of FXa inhibitors. Baseline was defined as the last value obtained prior to the start of the andexanet bolus. Hemostatic efficacy was achieved when the body had time to produce thrombin and a subsequent clot and was rated by the EAC as: excellent; good; poor/none; not evaluable due to non-administrative reasons; not evaluable due to administrative reasons. (NCT02329327)
Timeframe: Baseline, 12 Hours (post infusion)

InterventionPercent Change (Median)
Excellent/Good
FXa Inhibitor: Rivaroxaban - Additional Participants-96.3

Percent Change From Baseline In Anti-fXa Activity By Hemostatic Efficacy

This outcome measure assessed the relationship between hemostatic efficacy and anti-fXa activity in participants receiving an FXa inhibitor who had acute major bleeding. Anti-fXa activity was measured to assess the ability of andexanet to reverse the anticoagulant effect of FXa inhibitors. Baseline was defined as the last value obtained prior to the start of the andexanet bolus. Hemostatic efficacy was achieved when the body had time to produce thrombin and a subsequent clot and was rated by the EAC as: excellent; good; poor/none; not evaluable due to non-administrative reasons; not evaluable due to administrative reasons. (NCT02329327)
Timeframe: Baseline, 12 Hours (post infusion)

,,,
InterventionPercent Change (Median)
Excellent/GoodPoor/None
FXa Inhibitor: Apixaban-93.4-93.3
FXa Inhibitor: Edoxaban-75.8-65.2
FXa Inhibitor: Enoxaparin-75.20-78.44
FXa Inhibitor: Rivaroxaban-94.6-92.4

Reviews

6 reviews available for dalteparin and Cardiovascular Diseases

ArticleYear
Update on the clinical use of the low-molecular-weight heparin, parnaparin.
    Vascular health and risk management, 2009, Volume: 5

    Topics: Acute Coronary Syndrome; Anticoagulants; Arterial Occlusive Diseases; Cardiovascular Diseases; Drug

2009
Parnaparin : a review of its use in the management of venous thromboembolism, chronic venous disease and other vascular disorders.
    Drugs, 2008, Volume: 68, Issue:1

    Topics: Anticoagulants; Cardiovascular Diseases; Chronic Disease; Drug Administration Schedule; Fibrinolytic

2008
Hospital-based clinical implications of the novel oral anticoagulant, dabigatran etexilate, in daily practice.
    Hospital practice (1995), 2011, Volume: 39, Issue:3

    Topics: Antithrombins; Benzimidazoles; Blood Coagulation Tests; Cardiovascular Diseases; Clinical Trials as

2011
Increased major bleeding risk in patients with kidney dysfunction receiving enoxaparin: a meta-analysis.
    European journal of clinical pharmacology, 2012, Volume: 68, Issue:5

    Topics: Anticoagulants; Cardiovascular Diseases; Enoxaparin; Glomerular Filtration Rate; Hemorrhage; Humans;

2012
Thromboprophylaxis in medical patients: focus on France.
    Seminars in thrombosis and hemostasis, 2002, Volume: 28 Suppl 3

    Topics: Acute Disease; Adult; Aged; Attitude of Health Personnel; Cardiovascular Diseases; Double-Blind Meth

2002
Low-molecular-weight heparins in clinical practice.
    Southern medical journal, 1998, Volume: 91, Issue:1

    Topics: Anticoagulants; Cardiovascular Diseases; Clinical Trials as Topic; Dalteparin; Enoxaparin; Fibrinoly

1998

Trials

9 trials available for dalteparin and Cardiovascular Diseases

ArticleYear
Enoxaparin for outpatients with COVID-19: 90-day results from the randomised, open-label, parallel-group, multinational, phase III OVID trial.
    Thrombosis research, 2023, Volume: 221

    Topics: Adult; Anticoagulants; Cardiovascular Diseases; COVID-19; Enoxaparin; Female; Humans; Male; Middle A

2023
Enoxaparin for outpatients with COVID-19: 90-day results from the randomised, open-label, parallel-group, multinational, phase III OVID trial.
    Thrombosis research, 2023, Volume: 221

    Topics: Adult; Anticoagulants; Cardiovascular Diseases; COVID-19; Enoxaparin; Female; Humans; Male; Middle A

2023
Enoxaparin for outpatients with COVID-19: 90-day results from the randomised, open-label, parallel-group, multinational, phase III OVID trial.
    Thrombosis research, 2023, Volume: 221

    Topics: Adult; Anticoagulants; Cardiovascular Diseases; COVID-19; Enoxaparin; Female; Humans; Male; Middle A

2023
Enoxaparin for outpatients with COVID-19: 90-day results from the randomised, open-label, parallel-group, multinational, phase III OVID trial.
    Thrombosis research, 2023, Volume: 221

    Topics: Adult; Anticoagulants; Cardiovascular Diseases; COVID-19; Enoxaparin; Female; Humans; Male; Middle A

2023
Enoxaparin for outpatients with COVID-19: 90-day results from the randomised, open-label, parallel-group, multinational, phase III OVID trial.
    Thrombosis research, 2023, Volume: 221

    Topics: Adult; Anticoagulants; Cardiovascular Diseases; COVID-19; Enoxaparin; Female; Humans; Male; Middle A

2023
Enoxaparin for outpatients with COVID-19: 90-day results from the randomised, open-label, parallel-group, multinational, phase III OVID trial.
    Thrombosis research, 2023, Volume: 221

    Topics: Adult; Anticoagulants; Cardiovascular Diseases; COVID-19; Enoxaparin; Female; Humans; Male; Middle A

2023
Enoxaparin for outpatients with COVID-19: 90-day results from the randomised, open-label, parallel-group, multinational, phase III OVID trial.
    Thrombosis research, 2023, Volume: 221

    Topics: Adult; Anticoagulants; Cardiovascular Diseases; COVID-19; Enoxaparin; Female; Humans; Male; Middle A

2023
Enoxaparin for outpatients with COVID-19: 90-day results from the randomised, open-label, parallel-group, multinational, phase III OVID trial.
    Thrombosis research, 2023, Volume: 221

    Topics: Adult; Anticoagulants; Cardiovascular Diseases; COVID-19; Enoxaparin; Female; Humans; Male; Middle A

2023
Enoxaparin for outpatients with COVID-19: 90-day results from the randomised, open-label, parallel-group, multinational, phase III OVID trial.
    Thrombosis research, 2023, Volume: 221

    Topics: Adult; Anticoagulants; Cardiovascular Diseases; COVID-19; Enoxaparin; Female; Humans; Male; Middle A

2023
Comparison of Fatal or Irreversible Events With Extended-Duration Betrixaban Versus Standard Dose Enoxaparin in Acutely Ill Medical Patients: An APEX Trial Substudy.
    Journal of the American Heart Association, 2017, Jul-11, Volume: 6, Issue:7

    Topics: Acute Disease; Adult; Aged; Anticoagulants; Benzamides; Cardiovascular Diseases; Double-Blind Method

2017
Andexanet Alfa for Acute Major Bleeding Associated with Factor Xa Inhibitors.
    The New England journal of medicine, 2016, 09-22, Volume: 375, Issue:12

    Topics: Acute Disease; Aged; Aged, 80 and over; Cardiovascular Diseases; Enoxaparin; Factor Xa; Factor Xa In

2016
Andexanet Alfa for Acute Major Bleeding Associated with Factor Xa Inhibitors.
    The New England journal of medicine, 2016, 09-22, Volume: 375, Issue:12

    Topics: Acute Disease; Aged; Aged, 80 and over; Cardiovascular Diseases; Enoxaparin; Factor Xa; Factor Xa In

2016
Andexanet Alfa for Acute Major Bleeding Associated with Factor Xa Inhibitors.
    The New England journal of medicine, 2016, 09-22, Volume: 375, Issue:12

    Topics: Acute Disease; Aged; Aged, 80 and over; Cardiovascular Diseases; Enoxaparin; Factor Xa; Factor Xa In

2016
Andexanet Alfa for Acute Major Bleeding Associated with Factor Xa Inhibitors.
    The New England journal of medicine, 2016, 09-22, Volume: 375, Issue:12

    Topics: Acute Disease; Aged; Aged, 80 and over; Cardiovascular Diseases; Enoxaparin; Factor Xa; Factor Xa In

2016
Aspirin, warfarin, or enoxaparin thromboprophylaxis in patients with multiple myeloma treated with thalidomide: a phase III, open-label, randomized trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Mar-10, Volume: 29, Issue:8

    Topics: Aged; Anticoagulants; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspirin

2011
Aspirin, warfarin, or enoxaparin thromboprophylaxis in patients with multiple myeloma treated with thalidomide: a phase III, open-label, randomized trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Mar-10, Volume: 29, Issue:8

    Topics: Aged; Anticoagulants; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspirin

2011
Aspirin, warfarin, or enoxaparin thromboprophylaxis in patients with multiple myeloma treated with thalidomide: a phase III, open-label, randomized trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Mar-10, Volume: 29, Issue:8

    Topics: Aged; Anticoagulants; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspirin

2011
Aspirin, warfarin, or enoxaparin thromboprophylaxis in patients with multiple myeloma treated with thalidomide: a phase III, open-label, randomized trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Mar-10, Volume: 29, Issue:8

    Topics: Aged; Anticoagulants; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspirin

2011
Correlation of antifactor Xa concentrations with renal function in patients on enoxaparin.
    Journal of clinical pharmacology, 2003, Volume: 43, Issue:6

    Topics: Aged; Aged, 80 and over; Anticoagulants; Cardiovascular Diseases; Enoxaparin; Factor Xa; Female; Hum

2003
Safety and efficacy of enoxaparin compared with unfractionated heparin and oral anticoagulants for prevention of thromboembolic complications in cardioversion of nonvalvular atrial fibrillation: the Anticoagulation in Cardioversion using Enoxaparin (ACE)
    Circulation, 2004, Mar-02, Volume: 109, Issue:8

    Topics: Administration, Oral; Aged; Anticoagulants; Atrial Fibrillation; Cardiovascular Diseases; Drug Thera

2004
Dosage of enoxaparin among obese and renal impairment patients.
    Thrombosis research, 2005, Volume: 116, Issue:1

    Topics: Aged; Blood Coagulation Tests; Body Weight; Cardiovascular Diseases; Drug Monitoring; Enoxaparin; Fa

2005
Cardiac events after low osmolar ionic or isosmolar nonionic contrast media utilization in the current era of coronary angioplasty.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2006, Volume: 67, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Contrast Media; Coronary Angio

2006
[Monitoring of tinzaparin in a ten day treatment dose in elderly patients].
    La Revue de medecine interne, 2001, Volume: 22, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Cardiovascular Diseases; Creatinine; Drug Administration Sched

2001

Other Studies

14 other studies available for dalteparin and Cardiovascular Diseases

ArticleYear
[The initial experience of using fraxiparin in extracorporeal detoxication in clinical cardiology].
    Klinicheskaia khirurgiia, 1994, Issue:12

    Topics: Anticoagulants; Cardiovascular Diseases; Combined Modality Therapy; Drug Evaluation; Heparin; Humans

1994
Detection and analysis of potential drug-drug interactions among patients admitted to the cardiac care unit in a tertiary care hospital.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:2

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Enoxaparin; Furosemide; Humans; Li

2023
Prognostic factors and predictors of outcome in patients with COVID-19 and related pneumonia: a retrospective cohort study.
    Bioscience reports, 2020, 12-23, Volume: 40, Issue:12

    Topics: Aged; Aged, 80 and over; Anticoagulants; Antiviral Agents; Cardiovascular Diseases; Comorbidity; COV

2020
Vascular endothelial growth factor and soluble vascular endothelial growth factor receptor-1 in patients with end-stage renal disease. Associations with laboratory findings, comorbidities, and medications.
    Saudi medical journal, 2018, Volume: 39, Issue:6

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Aspirin; Calcium Channel Blockers; Cardiovascu

2018
The evolving role of dabigatran etexilate in clinical practice.
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:13

    Topics: Antithrombins; Arthroplasty, Replacement, Knee; Atrial Fibrillation; Cardiovascular Diseases; Clinic

2015
Primary percutaneous coronary intervention for ST-elevation myocardial infarction using an intravenous and subcutaneous enoxaparin low molecular weight heparin regimen.
    Journal of thrombosis and thrombolysis, 2008, Volume: 26, Issue:2

    Topics: Aged; Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Enoxaparin; Female; Fibrinolytic Agen

2008
Efficacy and safety of enoxaparin in combination with and without GP IIb/IIIa inhibitors in unselected patients with ST segment elevation myocardial infarction treated with primary percutaneous coronary intervention.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2009, Volume: 4, Issue:4

    Topics: Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Drug Therapy, Combination; Enoxaparin; Fibr

2009
Comparison of the antiangiogenic effects of heparin sodium, enoxaparin sodium, and tinzaparin sodium by using chorioallantoic membrane assay.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2012, Volume: 23, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Anticoagulants; Biological Assay; Cardiovascular Diseases; Chick E

2012
Outcome of noncardiac and nonvascular surgery in patients with mechanical heart valves.
    The American journal of cardiology, 2012, Aug-15, Volume: 110, Issue:4

    Topics: Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Cardiovascular Diseases; Case-Control

2012
[Cerebrovascular complications in metabolic syndrome: possible approaches to decrease risk].
    Terapevticheskii arkhiv, 2004, Volume: 76, Issue:6

    Topics: Adult; Anticoagulants; Blood Glucose; Blood Pressure; Body Mass Index; Brain; C-Peptide; Cardiovascu

2004
Adjusting the dose of low molecular weight heparins in renally impaired and obese patients.
    Clinical advances in hematology & oncology : H&O, 2004, Volume: 2, Issue:5

    Topics: Anticoagulants; Biomarkers; Cardiovascular Diseases; Comorbidity; Creatinine; Dose-Response Relation

2004
Massive rectus sheath hematoma.
    American journal of surgery, 2006, Volume: 191, Issue:1

    Topics: Aged; Anticoagulants; Aspirin; Cardiovascular Diseases; Enoxaparin; Epigastric Arteries; Female; Hem

2006
Antiplatelet drugs in cardiovascular prevention: coronary events: acute phase and secondary prevention.
    Prescrire international, 2000, Volume: 9, Issue:47

    Topics: Angina, Unstable; Angioplasty; Anticoagulants; Aspirin; Cardiovascular Diseases; Clinical Trials as

2000
Depo-heparin for long term therapy of myocardial infarction.
    The Journal of the Medical Society of New Jersey, 1952, Volume: 49, Issue:8

    Topics: Cardiovascular Diseases; Dalteparin; Heparin; Humans; Myocardial Infarction

1952