Page last updated: 2024-10-18

dalteparin and Cancer of Gastrointestinal Tract

dalteparin has been researched along with Cancer of Gastrointestinal Tract in 8 studies

Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)

Research Excerpts

ExcerptRelevanceReference
" Major bleeding occurred in 22 of 576 patients on apixaban (3."9.41Bleeding with Apixaban and Dalteparin in Patients with Cancer-Associated Venous Thromboembolism: Results from the Caravaggio Study. ( Ageno, W; Agnelli, G; Bauersachs, R; Becattini, C; Cohen, A; Gussoni, G; Huisman, M; Vedovati, MC, 2021)
"Apixaban has a higher rate of major bleeding in patients with luminal GI cancer compared with patients with non-GI cancer and compared with enoxaparin in patients with luminal GI cancer."8.02Bleeding in Patients With Gastrointestinal Cancer Compared With Nongastrointestinal Cancer Treated With Apixaban, Rivaroxaban, or Enoxaparin for Acute Venous Thromboembolism. ( Brunton, N; Casanegra, AI; Froehling, DA; Hodge, DO; Houghton, DE; McBane, RD; Meverden, RA; Peterson, LG; Vlazny, DT; Wysokinski, WE, 2021)
"Malignancy is a well-established risk factor for venous thromboembolism and while low-molecular-weight heparin therapy has been standard of care for cancer-associated thrombosis for many years, many patients find injection therapy burdensome."5.51Cost-effectiveness of edoxaban versus dalteparin for the treatment of cancer-associated thrombosis. ( Connell, NT; Connors, JM, 2019)
" Major bleeding occurred in 22 of 576 patients on apixaban (3."5.41Bleeding with Apixaban and Dalteparin in Patients with Cancer-Associated Venous Thromboembolism: Results from the Caravaggio Study. ( Ageno, W; Agnelli, G; Bauersachs, R; Becattini, C; Cohen, A; Gussoni, G; Huisman, M; Vedovati, MC, 2021)
"Apixaban has a higher rate of major bleeding in patients with luminal GI cancer compared with patients with non-GI cancer and compared with enoxaparin in patients with luminal GI cancer."4.02Bleeding in Patients With Gastrointestinal Cancer Compared With Nongastrointestinal Cancer Treated With Apixaban, Rivaroxaban, or Enoxaparin for Acute Venous Thromboembolism. ( Brunton, N; Casanegra, AI; Froehling, DA; Hodge, DO; Houghton, DE; McBane, RD; Meverden, RA; Peterson, LG; Vlazny, DT; Wysokinski, WE, 2021)
"Malignancy is a well-established risk factor for venous thromboembolism and while low-molecular-weight heparin therapy has been standard of care for cancer-associated thrombosis for many years, many patients find injection therapy burdensome."1.51Cost-effectiveness of edoxaban versus dalteparin for the treatment of cancer-associated thrombosis. ( Connell, NT; Connors, JM, 2019)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (37.50)24.3611
2020's5 (62.50)2.80

Authors

AuthorsStudies
Alexander, M1
Harris, S1
Underhill, C1
Torres, J1
Sharma, S1
Lee, N1
Wong, H1
Eek, R1
Michael, M1
Tie, J1
Rogers, J1
Heriot, AG1
Ball, D1
MacManus, M1
Wolfe, R1
Solomon, BJ1
Burbury, K1
Dziri, C1
Ben Hmida, W1
Dougaz, W1
Khalfallah, M1
Samaali, I1
Jerraya, H1
Bouasker, I1
Nouira, R1
Obitsu, T1
Tanaka, N1
Oyama, A1
Ueno, T1
Saito, M1
Yamaguchi, T1
Takagi, A1
Rikiyama, T1
Unno, M1
Naitoh, T1
Houghton, DE1
Vlazny, DT1
Casanegra, AI1
Brunton, N1
Froehling, DA1
Meverden, RA1
Hodge, DO1
Peterson, LG1
McBane, RD1
Wysokinski, WE1
Ladha, A1
Alam, A1
Idestrup, C1
Sawyer, J1
Choi, S1
Ageno, W1
Vedovati, MC1
Cohen, A1
Huisman, M1
Bauersachs, R1
Gussoni, G1
Becattini, C1
Agnelli, G1
Abdel-Razeq, H1
Finianos, A1
Taher, AT1
Connell, NT1
Connors, JM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Standardized, Guidelines Directed But Patients Oriented Clinical Practice Prospectively Registered[NCT03504007]10,000 participants (Anticipated)Observational2013-03-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for dalteparin and Cancer of Gastrointestinal Tract

ArticleYear
The use of direct oral anticoagulants in the treatment of acute venous thromboembolism in cancer patients.
    Expert review of hematology, 2018, Volume: 11, Issue:6

    Topics: Acute Disease; Administration, Oral; Anticoagulants; Dalteparin; Gastrointestinal Neoplasms; Humans;

2018

Trials

3 trials available for dalteparin and Cancer of Gastrointestinal Tract

ArticleYear
Biosimilar versus branded enoxaparin to prevent postoperative venous thromboembolism after surgery for digestive tract cancer: Randomized trial.
    PloS one, 2023, Volume: 18, Issue:11

    Topics: Anticoagulants; Biosimilar Pharmaceuticals; Enoxaparin; Gastrointestinal Neoplasms; Humans; Postoper

2023
Efficacy and Safety of Low-Molecular-Weight Heparin on Prevention of Venous Thromboembolism after Laparoscopic Operation for Gastrointestinal Malignancy in Japanese Patients: A Multicenter, Open-Label, Prospective, Randomized Controlled Trial.
    Journal of the American College of Surgeons, 2020, Volume: 231, Issue:5

    Topics: Adult; Aged; Contrast Media; Drug Administration Schedule; Enoxaparin; Female; Gastrointestinal Neop

2020
Bleeding with Apixaban and Dalteparin in Patients with Cancer-Associated Venous Thromboembolism: Results from the Caravaggio Study.
    Thrombosis and haemostasis, 2021, Volume: 121, Issue:5

    Topics: Aged; Dalteparin; Drug-Related Side Effects and Adverse Reactions; Female; Fibrinolytic Agents; Gast

2021

Other Studies

4 other studies available for dalteparin and Cancer of Gastrointestinal Tract

ArticleYear
Risk-Directed Ambulatory Thromboprophylaxis in Lung and Gastrointestinal Cancers: The TARGET-TP Randomized Clinical Trial.
    JAMA oncology, 2023, Nov-01, Volume: 9, Issue:11

    Topics: Adult; Aged; Anticoagulants; Biomarkers; Enoxaparin; Gastrointestinal Neoplasms; Hemorrhage; Humans;

2023
Bleeding in Patients With Gastrointestinal Cancer Compared With Nongastrointestinal Cancer Treated With Apixaban, Rivaroxaban, or Enoxaparin for Acute Venous Thromboembolism.
    Mayo Clinic proceedings, 2021, Volume: 96, Issue:11

    Topics: Enoxaparin; Factor Xa Inhibitors; Female; Gastrointestinal Neoplasms; Hemorrhage; Humans; Liver Neop

2021
Spinal haematoma after removal of a thoracic epidural catheter in a patient with coagulopathy resulting from unexpected vitamin K deficiency.
    Anaesthesia, 2013, Volume: 68, Issue:8

    Topics: Aged; Analgesia, Epidural; Anesthesia, General; Anticoagulants; Blood Coagulation Disorders; Blood C

2013
Cost-effectiveness of edoxaban versus dalteparin for the treatment of cancer-associated thrombosis.
    Journal of thrombosis and thrombolysis, 2019, Volume: 48, Issue:3

    Topics: Anticoagulants; Cost-Benefit Analysis; Dalteparin; Gastrointestinal Neoplasms; Humans; Markov Chains

2019