Page last updated: 2024-10-18

dalteparin and Burns

dalteparin has been researched along with Burns in 13 studies

Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)

Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.

Research Excerpts

ExcerptRelevanceReference
" The evidence suggests a need to evaluate different dosing protocols among burns patients in order to improve AFXa levels, with the aim of decreasing incidence of VTE in high-risk patients."1.62Venous thromboembolism in burns patients: Are we underestimating the risk and underdosing our prophylaxis? ( Bortz, H; Cleland, H; Harms, KA; Lo, C; Lu, P; Paul, E, 2021)
" Our objective was to evaluate the efficacy of enoxaparin dosed 40 mg twice daily in achieving prophylactic plasma anti-Xa levels in obese burn patients."1.62Single-center Experience with Venous Thromboembolism Prophylaxis for Obese Burn Patients. ( Jones, S; King, B; McKinzie, BP; Nizamani, R; Williams, FN, 2021)
" While 30-mg twice-daily enoxaparin is accepted as the standard prophylactic dose, recent evidence in injured patients suggests this dosing strategy may result in sub-optimal pharmacologic DVT prophylaxis."1.51Anti-Xa guided enoxaparin dose adjustment improves pharmacologic deep venous thrombosis prophylaxis in burn patients. ( Berndtson, AE; Box, K; Costantini, TW; Cronin, BJ; Godat, LN; Kolan, S; Lee, JG; Pham, A, 2019)
" We describe the first case report, to our knowledge, of a severely burned patient who, despite prophylactic dosing of enoxaparin 30 mg subcutaneously twice daily, developed an acute DVT that required high-dose enoxaparin (100 mg [1."1.48Increased Enoxaparin Dosing Requirements for Treatment of Deep Vein Thrombosis in a Severely Burned Patient: Case Report and Literature Review. ( Haan, BJ; Mangan, KC; Yost, RJ, 2018)
"The high prevalence of deep vein thrombosis (DVT) reported in prospective studies and the unreliability of clinical diagnosis mandates prospective screening for DVT in burn patients."1.43An analysis of deep vein thrombosis in burn patients (Part 1): Comparison of D-dimer and Doppler ultrasound as screening tools. ( Ahuja, RB; Bansal, P; Pradhan, GS; Subberwal, M, 2016)
"Frequent occurrence of low antifactor Xa levels observed in this study demonstrated the inadequacy of standard dosing of enoxaparin for VTE prophylaxis in many patients with acute burns."1.37Enoxaparin dose adjustment is associated with low incidence of venous thromboembolic events in acute burn patients. ( Cochran, A; Faraklas, I; Lin, H; Saffle, J, 2011)
" The low antifactor Xa levels that were observed suggest that a reduced dose-response relationship may exist between subcutaneously administered enoxaparin and antifactor Xa activity in patients with severe burn injuries."1.32Antifactor Xa levels in four patients with burn injuries who received enoxaparin to prevent venous thromboembolism. ( Angood, PB; Gandhi, PJ; Smith, BS; Yogaratnam, D, 2004)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (15.38)29.6817
2010's8 (61.54)24.3611
2020's3 (23.08)2.80

Authors

AuthorsStudies
Payne, A1
Richardson, P1
Muthayya, P1
Lu, P1
Harms, KA1
Paul, E1
Bortz, H1
Lo, C1
Cleland, H1
McKinzie, BP1
Nizamani, R1
Jones, S1
King, B1
Williams, FN1
Vicci, H1
Eblen-Zajjur, A1
López, M1
Crespo, G1
Navarro, M1
Yost, RJ1
Haan, BJ1
Mangan, KC1
Cronin, BJ1
Godat, LN1
Berndtson, AE1
Pham, A1
Kolan, S1
Box, K1
Lee, JG1
Costantini, TW1
Sebastian, R1
Ghanem, O1
DiRoma, F1
Milner, SM1
Price, LA1
Mojsiewicz-Pieńkowska, K1
Jamrógiewicz, M1
Żebrowska, M1
Mikolaszek, B1
Sznitowska, M1
Ahuja, RB2
Bansal, P2
Pradhan, GS2
Subberwal, M2
Lin, H1
Faraklas, I1
Saffle, J1
Cochran, A1
Yogaratnam, D1
Smith, BS1
Angood, PB1
Gandhi, PJ1
Ferguson, RE1
Critchfield, A1
Leclaire, A1
Ajkay, N1
Vasconez, HC1

Reviews

1 review available for dalteparin and Burns

ArticleYear
Pulmonary embolism in burns, is there an evidence based prophylactic recommendation? Case report and review of literature.
    Burns : journal of the International Society for Burn Injuries, 2015, Volume: 41, Issue:2

    Topics: Adult; Anticoagulants; Burns; Enoxaparin; Evidence-Based Medicine; Female; Humans; Obesity; Pulmonar

2015

Trials

2 trials available for dalteparin and Burns

ArticleYear
Double layer adhesive silicone dressing as a potential dermal drug delivery film in scar treatment.
    International journal of pharmaceutics, 2015, Mar-15, Volume: 481, Issue:1-2

    Topics: Adhesives; Administration, Cutaneous; Adult; Bandages; Burns; Cicatrix; Drug Delivery Systems; Enoxa

2015
An analysis of deep vein thrombosis in burn patients (part II): A randomized and controlled study of thrombo-prophylaxis with low molecular weight heparin.
    Burns : journal of the International Society for Burn Injuries, 2016, Volume: 42, Issue:8

    Topics: Adolescent; Adult; Body Surface Area; Burns; Disease Management; Enoxaparin; Epistaxis; Female; Fibr

2016

Other Studies

10 other studies available for dalteparin and Burns

ArticleYear
VTE prophylaxis and anti-factor Xa measurement in major burns: A survey of UK practice.
    Burns : journal of the International Society for Burn Injuries, 2023, Volume: 49, Issue:1

    Topics: Anticoagulants; Burns; Enoxaparin; Humans; United Kingdom; Venous Thromboembolism

2023
Venous thromboembolism in burns patients: Are we underestimating the risk and underdosing our prophylaxis?
    Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2021, Volume: 74, Issue:8

    Topics: Adult; Aged; Anticoagulants; Australia; Burns; Enoxaparin; Factor Xa Inhibitors; Female; Humans; Inc

2021
Single-center Experience with Venous Thromboembolism Prophylaxis for Obese Burn Patients.
    Journal of burn care & research : official publication of the American Burn Association, 2021, 05-07, Volume: 42, Issue:3

    Topics: Adult; Aged; Anticoagulants; Burns; Drug Administration Schedule; Enoxaparin; Female; Humans; Male;

2021
Enoxaparin pretreatment effect on local and systemic inflammation biomarkers in the animal burn model.
    Inflammopharmacology, 2019, Volume: 27, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Anticoagulants; Antithrombin III; Biomarkers; Burns; C-Reactive P

2019
Increased Enoxaparin Dosing Requirements for Treatment of Deep Vein Thrombosis in a Severely Burned Patient: Case Report and Literature Review.
    Pharmacotherapy, 2018, Volume: 38, Issue:11

    Topics: Adult; Anticoagulants; Burns; Enoxaparin; Factor Xa; Humans; Male; Monitoring, Physiologic; Venous T

2018
Anti-Xa guided enoxaparin dose adjustment improves pharmacologic deep venous thrombosis prophylaxis in burn patients.
    Burns : journal of the International Society for Burn Injuries, 2019, Volume: 45, Issue:4

    Topics: Adult; Aged; Anticoagulants; Blood Coagulation Tests; Body Mass Index; Body Weight; Burns; Chemoprev

2019
An analysis of deep vein thrombosis in burn patients (Part 1): Comparison of D-dimer and Doppler ultrasound as screening tools.
    Burns : journal of the International Society for Burn Injuries, 2016, Volume: 42, Issue:8

    Topics: Adolescent; Adult; Body Surface Area; Burns; Disease Management; Enoxaparin; Female; Fibrin Fibrinog

2016
Enoxaparin dose adjustment is associated with low incidence of venous thromboembolic events in acute burn patients.
    The Journal of trauma, 2011, Volume: 71, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Burn Units; Burns; Cohort

2011
Antifactor Xa levels in four patients with burn injuries who received enoxaparin to prevent venous thromboembolism.
    Pharmacotherapy, 2004, Volume: 24, Issue:12

    Topics: Adult; Antithrombin III; Burns; Enoxaparin; Female; Humans; Male; Venous Thrombosis

2004
Current practice of thromboprophylaxis in the burn population: a survey study of 84 US burn centers.
    Burns : journal of the International Society for Burn Injuries, 2005, Volume: 31, Issue:8

    Topics: Anticoagulants; Burn Units; Burns; Dalteparin; Enoxaparin; Health Surveys; Heparin; Humans; Risk Fac

2005