dalteparin has been researched along with Brain Injuries in 20 studies
Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The authors hypothesize that early chemoprophylaxis in patients with TBI is safe and efficacious." | 2.78 | Safety and efficacy of early thromboembolism chemoprophylaxis after intracranial hemorrhage from traumatic brain injury. ( Barnes, SL; Farooqui, A; Hiser, B; Litofsky, NS, 2013) |
| "Multiple studies have addressed deep vein thrombosis chemoprophylaxis timing in traumatic brain injuries." | 2.52 | Timing for deep vein thrombosis chemoprophylaxis in traumatic brain injury: an evidence-based review. ( Abdel-Aziz, H; Dunham, CM; Hileman, BM; Malik, RJ, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 15 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giannakaki, V | 1 |
| Triantafyllou, T | 1 |
| Drossos, D | 1 |
| Papapetrou, K | 1 |
| Farooqui, A | 1 |
| Hiser, B | 1 |
| Barnes, SL | 1 |
| Litofsky, NS | 1 |
| Pastorek, RA | 1 |
| Cripps, MW | 1 |
| Bernstein, IH | 1 |
| Scott, WW | 1 |
| Madden, CJ | 2 |
| Rickert, KL | 1 |
| Wolf, SE | 2 |
| Phelan, HA | 2 |
| Daley, MJ | 1 |
| Ali, S | 1 |
| Brown, CV | 1 |
| Abdel-Aziz, H | 1 |
| Dunham, CM | 1 |
| Malik, RJ | 1 |
| Hileman, BM | 1 |
| Li, S | 2 |
| Marks, JA | 1 |
| Eisenstadt, R | 2 |
| Kumasaka, K | 2 |
| Samadi, D | 1 |
| Johnson, VE | 2 |
| Holena, DN | 1 |
| Allen, SR | 1 |
| Browne, KD | 2 |
| Smith, DH | 2 |
| Pascual, JL | 2 |
| Marks, J | 1 |
| Nagata, K | 1 |
| Reiff, DA | 1 |
| Haricharan, RN | 1 |
| Bullington, NM | 1 |
| Griffin, RL | 1 |
| McGwin, G | 1 |
| Rue, LW | 1 |
| Dudley, RR | 1 |
| Aziz, I | 1 |
| Bonnici, A | 1 |
| Saluja, RS | 1 |
| Lamoureux, J | 1 |
| Kalmovitch, B | 1 |
| Gursahaney, A | 1 |
| Razek, T | 1 |
| Maleki, M | 1 |
| Marcoux, J | 1 |
| Salottolo, K | 1 |
| Offner, P | 1 |
| Levy, AS | 1 |
| Mains, CW | 1 |
| Slone, DS | 1 |
| Bar-Or, D | 1 |
| Sen, O | 1 |
| Sonmez, E | 1 |
| Cekinmez, M | 1 |
| Ozen, O | 1 |
| Caner, H | 1 |
| Minshall, CT | 1 |
| Eriksson, EA | 1 |
| Leon, SM | 1 |
| Doben, AR | 1 |
| McKinzie, BP | 1 |
| Fakhry, SM | 1 |
| Župan, Ž | 1 |
| Pilipović, K | 1 |
| Dangubić, B | 1 |
| Frković, V | 1 |
| Šustić, A | 1 |
| Župan, G | 1 |
| Broderick, PA | 1 |
| Kolodny, EH | 1 |
| Norwood, SH | 1 |
| Aldy, K | 1 |
| Brakenridge, SC | 1 |
| Eastman, AL | 1 |
| Nakonezny, PA | 1 |
| Yang, L | 1 |
| Chason, DP | 1 |
| Arbique, GM | 1 |
| Berne, J | 1 |
| Minei, JP | 1 |
| Ibrahim, A | 1 |
| Ashkan, K | 1 |
| Smith, M | 1 |
| Watkins, L | 1 |
| Wahl, F | 2 |
| Grosjean-Piot, O | 2 |
| Bareyre, F | 1 |
| Uzan, A | 2 |
| Stutzmann, JM | 2 |
| Mary, V | 1 |
| Pratt, J | 1 |
| Kleindienst, A | 1 |
| Harvey, HB | 1 |
| Mater, E | 1 |
| Bronst, J | 1 |
| Flack, J | 1 |
| Herenz, K | 1 |
| Haupt, WF | 1 |
| Schön, R | 1 |
| Ciapetti, M | 1 |
| Circelli, A | 1 |
| Zagli, G | 1 |
| Migliaccio, ML | 1 |
| Spina, R | 1 |
| Alessi, A | 1 |
| Acquafresca, M | 1 |
| Bartolini, M | 1 |
| Peris, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Improving Outcome in Subarachnoid Hemorrhage wIth Nadroparine[NCT04507178] | Phase 2 | 100 participants (Anticipated) | Interventional | 2022-02-02 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for dalteparin and Brain Injuries
| Article | Year |
|---|---|
Post-Traumatic Bifrontoparietal Extradural Hematoma with Superior Sagittal Sinus Detachment: A Case Report and Review of the Literature.
Topics: Adult; Anticoagulants; Anticonvulsants; Brain Injuries; Drug Therapy, Combination; Hematoma, Epidura | 2016 |
Timing for deep vein thrombosis chemoprophylaxis in traumatic brain injury: an evidence-based review.
Topics: Anticoagulants; Brain Injuries; Enoxaparin; Humans; Intracranial Hemorrhages; Risk Factors; Venous T | 2015 |
Neuroprotective profile of enoxaparin, a low molecular weight heparin, in in vivo models of cerebral ischemia or traumatic brain injury in rats: a review.
Topics: Animals; Anticoagulants; Brain Edema; Brain Injuries; Brain Ischemia; Cognition Disorders; Enoxapari | 2002 |
2 trials available for dalteparin and Brain Injuries
| Article | Year |
|---|---|
Safety and efficacy of early thromboembolism chemoprophylaxis after intracranial hemorrhage from traumatic brain injury.
Topics: Adult; Aged; Anticoagulants; Brain Injuries; Chemoprevention; Clinical Protocols; Cohort Studies; En | 2013 |
A randomized, double-blinded, placebo-controlled pilot trial of anticoagulation in low-risk traumatic brain injury: The Delayed Versus Early Enoxaparin Prophylaxis I (DEEP I) study.
Topics: Adult; Anticoagulants; Brain Injuries; Double-Blind Method; Enoxaparin; Female; Humans; Intracranial | 2012 |
15 other studies available for dalteparin and Brain Injuries
| Article | Year |
|---|---|
The Parkland Protocol's modified Berne-Norwood criteria predict two tiers of risk for traumatic brain injury progression.
Topics: Adult; Aged; Brain Injuries; Clinical Protocols; Disease Progression; Enoxaparin; Female; Fibrinolyt | 2014 |
Late venous thromboembolism prophylaxis after craniotomy in acute traumatic brain injury.
Topics: Adult; Anticoagulants; Brain Injuries; Craniotomy; Enoxaparin; Female; Hospital Mortality; Humans; M | 2015 |
Enoxaparin ameliorates post-traumatic brain injury edema and neurologic recovery, reducing cerebral leukocyte endothelial interactions and vessel permeability in vivo.
Topics: Animals; Anticoagulants; Brain Edema; Brain Injuries; Endothelium, Vascular; Enoxaparin; Leukocytes; | 2015 |
Does enoxaparin interfere with HMGB1 signaling after TBI? A potential mechanism for reduced cerebral edema and neurologic recovery.
Topics: Animals; Antibodies, Monoclonal; Anticoagulants; Brain; Brain Edema; Brain Injuries; Cerebrovascular | 2016 |
Traumatic brain injury is associated with the development of deep vein thrombosis independent of pharmacological prophylaxis.
Topics: Adult; Age Distribution; Analysis of Variance; Anticoagulants; Brain Injuries; Chi-Square Distributi | 2009 |
Early venous thromboembolic event prophylaxis in traumatic brain injury with low-molecular-weight heparin: risks and benefits.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Brain Injuries; Chi-Square Distribution; | 2010 |
Interrupted pharmocologic thromboprophylaxis increases venous thromboembolism in traumatic brain injury.
Topics: Anticoagulants; Brain Injuries; Chi-Square Distribution; Enoxaparin; Female; Glasgow Coma Scale; Hep | 2011 |
Antithrombin III and enoxaparin treatment inhibit contusion-triggered cell death, inflammation, hemorrhage and apoptosis after severe traumatic brain injury in rats.
Topics: Animals; Anticoagulants; Antithrombin III; Antithrombins; Apoptosis; Brain Injuries; Disease Models, | 2011 |
Safety and efficacy of heparin or enoxaparin prophylaxis in blunt trauma patients with a head abbreviated injury severity score >2.
Topics: Abbreviated Injury Scale; Anticoagulants; Brain Injuries; Disease Progression; Enoxaparin; Heparin; | 2011 |
Effects of enoxaparin in the rat hippocampus following traumatic brain injury.
Topics: Animals; Anticoagulants; Apoptosis; Brain Injuries; Caspase 3; Enoxaparin; Glial Fibrillary Acidic P | 2011 |
Biosensors for brain trauma and dual laser doppler flowmetry: enoxaparin simultaneously reduces stroke-induced dopamine and blood flow while enhancing serotonin and blood flow in motor neurons of brain, in vivo.
Topics: Animals; Anticoagulants; Biosensing Techniques; Blood Flow Velocity; Brain Injuries; Dopamine; Elect | 2011 |
Anticoagulation in a head-injured patient.
Topics: Accidental Falls; Anticoagulants; Brain Injuries; Cerebral Hemorrhage; Contraindications; Enoxaparin | 2003 |
Enoxaparin reduces brain edema, cerebral lesions, and improves motor and cognitive impairments induced by a traumatic brain injury in rats.
Topics: Animals; Anticoagulants; Body Water; Brain; Brain Edema; Brain Injuries; Cognition; Cognition Disord | 2000 |
Early antithrombotic prophylaxis with low molecular weight heparin in neurosurgery.
Topics: Adult; Aged; Aged, 80 and over; Brain Injuries; Brain Neoplasms; Cerebrospinal Fluid Shunts; Contrai | 2003 |
Diagnosis of carotid arterial injury in major trauma using a modification of Memphis criteria.
Topics: Adult; Anticoagulants; Brain Injuries; Carotid Artery Injuries; Dalteparin; Humans; Intensive Care U | 2010 |