dalteparin has been researched along with Brain Infarction in 3 studies
Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)
Brain Infarction: Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Focal cerebral ischemia was induced by the intraluminal suture, middle cerebral artery occlusion (MCAO) method." | 1.32 | The low molecular weight heparin enoxaparin reduces infarct size in a rat model of temporary focal ischemia. ( Jonas, S; Li, YS; Quartermain, D, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Quartermain, D | 2 |
| Li, YS | 2 |
| Jonas, S | 2 |
| Sprigg, N | 1 |
| Gray, LJ | 1 |
| Bath, PM | 1 |
| Lindenstrøm, E | 1 |
| Boysen, G | 1 |
| De Deyn, PP | 1 |
| Friis, P | 1 |
| Leys, D | 1 |
| Marttila, R | 1 |
| Olsson, JE | 1 |
| O'Neill, D | 1 |
| Ringelstein, EB | 1 |
| van der Sande, JJ | 1 |
| Turpie, AG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pilot Study of Treatment With Intravenous Enoxaparin and/or Oral Minocycline to Limit Infarct Size After Ischemic Stroke[NCT00836355] | 6 participants (Actual) | Interventional | 2009-04-30 | Terminated (stopped due to Too few acute stroke patients available to meet enrollment requirements.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for dalteparin and Brain Infarction
| Article | Year |
|---|---|
Stroke severity, early recovery and outcome are each related with clinical classification of stroke: data from the 'Tinzaparin in Acute Ischaemic Stroke Trial' (TAIST).
Topics: Aged; Aged, 80 and over; Brain Infarction; Brain Ischemia; Cerebral Hemorrhage; Disease Progression; | 2007 |
2 other studies available for dalteparin and Brain Infarction
| Article | Year |
|---|---|
The low molecular weight heparin enoxaparin reduces infarct size in a rat model of temporary focal ischemia.
Topics: Animals; Anticoagulants; Brain Infarction; Brain Ischemia; Disease Models, Animal; Drug Administrati | 2003 |
Acute enoxaparin treatment widens the therapeutic window for tPA in a mouse model of embolic stroke.
Topics: Animals; Behavior, Animal; Brain Infarction; Disease Models, Animal; Drug Interactions; Enoxaparin; | 2007 |