dalteparin has been researched along with Blunt Injuries in 9 studies
Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Early enoxaparin-based anticoagulation may be a safe option in trauma patients with blunt solid organ injury." | 1.42 | Early thromboembolic prophylaxis in patients with blunt solid abdominal organ injuries undergoing nonoperative management: is it safe? ( Friese, RS; Green, DJ; Gries, L; Harrison, C; Joseph, B; Kulvatunyou, N; Lubin, D; O'Keeffe, T; Pandit, V; Rhee, P; Tang, A; Zangbar, B, 2015) |
| " The efficacy of daily dosing in critically ill patients is unknown." | 1.33 | Optimal dose of enoxaparin in critically ill trauma and surgical patients. ( Abrams, JE; Rutherford, EJ; Schooler, WG; Skeete, DA; Sredzienski, E, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Schroeppel, TJ | 1 |
| Clement, LP | 1 |
| Douville, AA | 1 |
| Schmoekel, NH | 1 |
| Stassinopoulos, J | 1 |
| Decker, C | 1 |
| Stillman, ZE | 1 |
| Rodriquez, J | 1 |
| Brockman, VP | 1 |
| Hennessy, E | 1 |
| Heise, H | 1 |
| Khan, AD | 1 |
| Marturano, MN | 1 |
| Khan, AR | 1 |
| DeBlieux, P | 1 |
| Wang, H | 1 |
| Ross, SW | 1 |
| Cunningham, KW | 1 |
| Sing, RF | 1 |
| Thomas, BW | 1 |
| Joseph, B | 1 |
| Pandit, V | 1 |
| Harrison, C | 1 |
| Lubin, D | 1 |
| Kulvatunyou, N | 1 |
| Zangbar, B | 1 |
| Tang, A | 1 |
| O'Keeffe, T | 1 |
| Green, DJ | 1 |
| Gries, L | 1 |
| Friese, RS | 1 |
| Rhee, P | 1 |
| Brunworth, LS | 1 |
| Cothren, CC | 1 |
| Kimm, GE | 1 |
| Biffl, WL | 1 |
| Moore, EE | 1 |
| Minshall, CT | 1 |
| Eriksson, EA | 1 |
| Leon, SM | 1 |
| Doben, AR | 1 |
| McKinzie, BP | 1 |
| Fakhry, SM | 1 |
| Rutherford, EJ | 1 |
| Schooler, WG | 1 |
| Sredzienski, E | 1 |
| Abrams, JE | 1 |
| Skeete, DA | 1 |
| Stannard, JP | 1 |
| Lopez-Ben, RR | 1 |
| Volgas, DA | 1 |
| Anderson, ER | 1 |
| Busbee, M | 1 |
| Karr, DK | 1 |
| McGwin, GR | 1 |
| Alonso, JE | 1 |
| Norwood, SH | 1 |
| McAuley, CE | 1 |
| Berne, JD | 1 |
| Vallina, VL | 1 |
| Kerns, DB | 1 |
| Grahm, TW | 1 |
| McLarty, JW | 1 |
| Ciapetti, M | 1 |
| Circelli, A | 1 |
| Zagli, G | 1 |
| Migliaccio, ML | 1 |
| Spina, R | 1 |
| Alessi, A | 1 |
| Acquafresca, M | 1 |
| Bartolini, M | 1 |
| Peris, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Different Approach to Preventing Thrombosis (ADAPT): A Randomized Controlled Trial Comparing Low Molecular Weight Heparin to Acetylsalicylic Acid in Orthopedic Trauma Patients[NCT02774265] | Phase 3 | 329 participants (Actual) | Interventional | 2016-01-31 | Completed | ||
| The Use of Low Molecular Weight Heparin in Traumatic Brain Injury[NCT00170378] | Phase 4 | 300 participants | Interventional | 2002-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
DVT and how the diagnosis was made will be recorded. The number of events in participants in each arm will be compared to evaluate efficacy. (NCT02774265)
Timeframe: 90 days
| Intervention | Participants (Count of Participants) |
|---|---|
| VTE Prophylaxis With Enoxaparin 30mg BID | 5 |
| VTE Prophylaxis With Aspirin 81mg BID | 9 |
Bases on imaging obtained for symptoms. (NCT02774265)
Timeframe: 90 days
| Intervention | Participants (Count of Participants) |
|---|---|
| VTE Prophylaxis With Enoxaparin 30mg BID | 6 |
| VTE Prophylaxis With Aspirin 81mg BID | 2 |
Includes a greater than 2g/dL drop in hemoglobin, blood transfusion, hematoma evacuation, re-operation for a deep surgical site infection or minor procedure for bleeding and GI bleed (NCT02774265)
Timeframe: 90 days
| Intervention | Participants (Count of Participants) |
|---|---|
| VTE Prophylaxis With Enoxaparin 30mg BID | 52 |
| VTE Prophylaxis With Aspirin 81mg BID | 53 |
1 trial available for dalteparin and Blunt Injuries
| Article | Year |
|---|---|
Prophylaxis against deep-vein thrombosis following trauma: a prospective, randomized comparison of mechanical and pharmacologic prophylaxis.
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Double-Blind Method; Enoxaparin; Humans; Middle Aged | 2006 |
8 other studies available for dalteparin and Blunt Injuries
| Article | Year |
|---|---|
Time is of the Essence: Impact of a More Aggressive Chemical Venous Thromboembolism Prophylaxis Regimen on Trauma Patients.
Topics: Adult; Aged; Algorithms; Anticoagulants; Blood Transfusion; Colorado; Enoxaparin; Female; Humans; In | 2022 |
Timing of venous thromboembolism chemoprophylaxis using objective hemoglobin criteria in blunt solid organ injury.
Topics: Anticoagulants; Chemoprevention; Enoxaparin; Humans; Retrospective Studies; Venous Thromboembolism; | 2023 |
Early thromboembolic prophylaxis in patients with blunt solid abdominal organ injuries undergoing nonoperative management: is it safe?
Topics: Abdominal Injuries; Adult; Aged; Anticoagulants; Drug Administration Schedule; Enoxaparin; Female; H | 2015 |
Pediatric blunt vertebral artery injury: case report and treatment plan.
Topics: Accidents, Traffic; Algorithms; Anticoagulants; Child; Enoxaparin; Humans; Male; Risk Factors; Spina | 2009 |
Safety and efficacy of heparin or enoxaparin prophylaxis in blunt trauma patients with a head abbreviated injury severity score >2.
Topics: Abbreviated Injury Scale; Anticoagulants; Brain Injuries; Disease Progression; Enoxaparin; Heparin; | 2011 |
Optimal dose of enoxaparin in critically ill trauma and surgical patients.
Topics: Anticoagulants; Critical Illness; Enoxaparin; Factor Xa Inhibitors; Fibrinolytic Agents; Humans; Pro | 2005 |
A potentially expanded role for enoxaparin in preventing venous thromboembolism in high risk blunt trauma patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Enoxaparin; Female; Humans; Male; Middle | 2001 |
Diagnosis of carotid arterial injury in major trauma using a modification of Memphis criteria.
Topics: Adult; Anticoagulants; Brain Injuries; Carotid Artery Injuries; Dalteparin; Humans; Intensive Care U | 2010 |