Page last updated: 2024-10-18

dalteparin and Arterial Obstructive Diseases

dalteparin has been researched along with Arterial Obstructive Diseases in 28 studies

Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)

Research Excerpts

ExcerptRelevanceReference
"The Fraxiparin in Stroke Study for the treatment of ischemic stroke (FISS-tris) study showed no superiority of low-molecular-weight heparin (LMWH) over aspirin for the primary end point (Barthel Index) in acute ischemic stroke due to large artery occlusive disease."9.16Low-molecular-weight heparin versus aspirin for acute ischemic stroke with large artery occlusive disease: subgroup analyses from the Fraxiparin in Stroke Study for the treatment of ischemic stroke (FISS-tris) study. ( Chen, C; Chen, XY; Han, JH; Leung, TW; Mok, V; Soo, Y; Wang, QS; Wong, KS, 2012)
" We present a unique case of ET causing extensive arterial thromboembolism, despite being on adequate antithrombotic agents including warfarin and aspirin."7.85Medical Management of Extensive Arterial Thromboembolism in a Patient with Essential Thrombocythemia and Warfarin Failure. ( Ahmed, AK; Skeik, N; Youssef, A, 2017)
"Warfarin-induced skin necrosis is a rare complication associated with the use of oral anticoagulants."7.72A case of warfarin skin necrosis despite enoxaparin anticoagulation in a patient with protein S deficiency. ( Alexander, JB; Ierardi, R; Tai, CY, 2004)
" Our case report suggests that antithrombotic treatment by targeting of the activated platelets with a potent platelet inhibitor during the acute phase of type II HIT syndrome followed by long-term administration of oral anticoagulation may be an additional, safe and effective therapeutic alternative that merits to be systematically studied."5.33Recurrent arterial thromboses in a woman with heparin induced thrombocytopenia, successfully managed with iloprost followed by clopidogrel. An alternative therapeutic option for heparin induced thrombocytopenia type II syndrome. ( Alexandridou, S; Betsis, D; Blouhos, K; Megalopoulos, A; Tsachalis, T; Tsalis, K; Vasiliadis, K, 2006)
"The Fraxiparin in Stroke Study for the treatment of ischemic stroke (FISS-tris) study showed no superiority of low-molecular-weight heparin (LMWH) over aspirin for the primary end point (Barthel Index) in acute ischemic stroke due to large artery occlusive disease."5.16Low-molecular-weight heparin versus aspirin for acute ischemic stroke with large artery occlusive disease: subgroup analyses from the Fraxiparin in Stroke Study for the treatment of ischemic stroke (FISS-tris) study. ( Chen, C; Chen, XY; Han, JH; Leung, TW; Mok, V; Soo, Y; Wang, QS; Wong, KS, 2012)
"After successful PTA, 275 patients with symptomatic peripheral arterial disease (claudication or critical limb ischemia) and femoropopliteal obstructions were randomized to receive either 2500 IU of dalteparin subcutaneously for 3 months plus 100 mg of aspirin daily (n = 137), or 100 mg aspirin daily alone (n = 138)."5.12Low-molecular-weight heparin for prevention of restenosis after femoropopliteal percutaneous transluminal angioplasty: a randomized controlled trial. ( Amann-Vesti, BR; Banyai, M; Koppensteiner, R; Meier, T; Pfammatter, T; Rousson, V; Spring, S; van der Loo, B, 2006)
"We report a case of ophthalmic artery occlusion (OAO) in a young patient with COVID-19 infection that was on therapeutic anticoagulation with apixaban for deep venous thrombosis (DVT)."3.96Acute ophthalmic artery occlusion in a COVID-19 patient on apixaban. ( Biousse, V; Bose, S; Dumitrascu, OM; Lyden, PD; Volod, O; Wang, Y, 2020)
" We present a unique case of ET causing extensive arterial thromboembolism, despite being on adequate antithrombotic agents including warfarin and aspirin."3.85Medical Management of Extensive Arterial Thromboembolism in a Patient with Essential Thrombocythemia and Warfarin Failure. ( Ahmed, AK; Skeik, N; Youssef, A, 2017)
"Warfarin-induced skin necrosis is a rare complication associated with the use of oral anticoagulants."3.72A case of warfarin skin necrosis despite enoxaparin anticoagulation in a patient with protein S deficiency. ( Alexander, JB; Ierardi, R; Tai, CY, 2004)
" The general use and correct dosage of low-molecular-weight heparin, however, are still under debate."2.70Low-molecular-weight heparin in arterial reconstructive surgery: a double-blind, randomized dose-finding trial. ( Eckmann, C; Kujath, P; Misselwitz, F, 2002)
"BACKGROUND Coronavirus disease 2019 (COVID-19) has a tremendous impact on the respiratory tract."1.72A Patient-Tailored Approach to Management of Acute Limb Ischemia in Patients with COVID-19: A Case Series. ( AlGhofili, H; Alhumaid, A; Aljabri, B; Altoijry, A; Iqbal, K, 2022)
" In the patients of both groups the product dabigatran etexilate in the standard dosage (220 mg/day) was used for specific prevention."1.43[Substantiation of the system of thrombus formation prevention in treatment of patients with hip joint pathology against the background of arterial insufficiency of the lower extremities]. ( Akhtyamov, IF; Shigaev, ES; Ziatdinov, BG, 2016)
" Protocols vary from center to center, but there is still no consensus regarding the proper dosage or treatment duration."1.42The Use of Low-Dose Recombinant Tissue Plasminogen Activator to Treat a Preterm Infant with an Intrauterine Spontaneous Arterial Thromboembolism. ( Caner, İ; Demirelli, Y; Kara, M; Tekgündüz, KŞ, 2015)
"Acute pulmonary embolism is an important emergency disease which frequently results in life-threatening complication."1.39Effectiveness of low-dose prolonged infusion of tissue plasminogen activator in a nonagenarian patient with acute pulmonary embolism and main pulmonary artery thrombus. ( Acar, RD; Karakoyun, S; Ozkan, M; Yildiz, M, 2013)
"Dabigatran was stopped and dalteparin 5000 International Units/bid and 40 μg alprostadil infusions were started."1.38Fatal basilar artery occlusion under dabigatran occurring 13 days after femoral embolectomy. ( Finsterer, J; Reiter, M; Schäffl-Doweik, L; Stöllberger, C, 2012)
" Our case report suggests that antithrombotic treatment by targeting of the activated platelets with a potent platelet inhibitor during the acute phase of type II HIT syndrome followed by long-term administration of oral anticoagulation may be an additional, safe and effective therapeutic alternative that merits to be systematically studied."1.33Recurrent arterial thromboses in a woman with heparin induced thrombocytopenia, successfully managed with iloprost followed by clopidogrel. An alternative therapeutic option for heparin induced thrombocytopenia type II syndrome. ( Alexandridou, S; Betsis, D; Blouhos, K; Megalopoulos, A; Tsachalis, T; Tsalis, K; Vasiliadis, K, 2006)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.57)18.2507
2000's12 (42.86)29.6817
2010's13 (46.43)24.3611
2020's2 (7.14)2.80

Authors

AuthorsStudies
Bang, OY1
Kim, JS1
Wang, QS1
Chen, C2
Chen, XY1
Han, JH1
Soo, Y1
Leung, TW1
Mok, V1
Wong, KS2
Mazzone, A1
Giani, L1
Faggioli, P1
Pichini, S1
Pacifici, R1
Ng, PW1
Tsoi, TH1
Li, HL1
Fong, WC1
Yeung, J1
Wong, CK1
Yip, KK1
Gao, H1
Wong, HB1
Schweizer, J1
Müller, A1
Forkmann, L1
Hellner, G1
Kirch, W1
Camporese, G1
Bernardi, E1
Noventa, F1
Alhumaid, A1
Altoijry, A1
Aljabri, B1
Iqbal, K1
AlGhofili, H1
Dumitrascu, OM1
Volod, O1
Bose, S1
Wang, Y1
Biousse, V1
Lyden, PD1
Demirelli, Y1
Tekgündüz, KŞ1
Caner, İ1
Kara, M1
Beato, J1
Fígueira, L1
Penas, S1
Santos-Silva, R1
Falcão, M1
Carneiro, Â1
Reis, FF1
Akhtyamov, IF1
Ziatdinov, BG1
Shigaev, ES1
Ahmed, AK1
Youssef, A1
Skeik, N1
Feray, H1
Izgi, C1
Cetiner, D1
Men, EE1
Saltan, Y1
Baltay, A1
Kahraman, R1
Raynaud, A1
Novelli, L1
Rovani, X1
Carreres, T1
Bourquelot, P1
Hermelin, A1
Angel, C1
Beyssen, B1
Duschek, N1
Vafaie, M1
Skrinjar, E1
Hirsch, K1
Waldhör, T1
Hübl, W1
Bergmayr, W1
Knoebl, P1
Assadian, A1
Stöllberger, C1
Reiter, M1
Schäffl-Doweik, L1
Finsterer, J1
Yildiz, M1
Karakoyun, S1
Acar, RD1
Ozkan, M1
Tai, CY1
Ierardi, R1
Alexander, JB1
Hans, GA1
Senard, M1
Ledoux, D1
Grayet, B1
Scholtes, F1
Creemers, E1
Lamy, ML1
Kujath, P1
Eckmann, C1
Misselwitz, F1
Göttman, D1
Strecker, EP1
Boos, I1
Vetter, S1
Skeppholm, M1
Kallner, A1
Kalani, M2
Jörneskog, G2
Blombäck, M2
Wallén, HN1
Pokrovskiĭ, AV1
Gontarenko, VN1
Titova, MI1
Apelqvist, J1
Brismar, K1
Eliasson, B1
Eriksson, JW1
Fagrell, B1
Hamsten, A1
Torffvit, O1
Kovacs, MJ1
Kearon, C1
Rodger, M1
Anderson, DR1
Turpie, AG1
Bates, SM1
Desjardins, L1
Douketis, J1
Kahn, SR1
Solymoss, S1
Wells, PS1
Koppensteiner, R1
Spring, S1
Amann-Vesti, BR1
Meier, T1
Pfammatter, T1
Rousson, V1
Banyai, M1
van der Loo, B1
Telen, MJ1
Batchvarova, M1
Shan, S1
Bovee-Geurts, PH1
Zennadi, R1
Leitgeb, A1
Brock, R1
Lindgren, M1
Megalopoulos, A1
Vasiliadis, K1
Tsachalis, T1
Tsalis, K1
Blouhos, K1
Alexandridou, S1
Betsis, D1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Double Blind Randomized Control Trial of Post-Operative Low Molecular Weight Heparin Bridging Therapy Versus Placebo Bridging Therapy for Patients Who Are at High Risk for Arterial Thromboembolism (PERIOP 2)[NCT00432796]Phase 31,473 participants (Actual)Interventional2006-12-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for dalteparin and Arterial Obstructive Diseases

ArticleYear
Update on the clinical use of the low-molecular-weight heparin, parnaparin.
    Vascular health and risk management, 2009, Volume: 5

    Topics: Acute Coronary Syndrome; Anticoagulants; Arterial Occlusive Diseases; Cardiovascular Diseases; Drug

2009
[Administration of dalteparin in reconstructive vascular surgery].
    Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery, 2011, Volume: 17, Issue:2

    Topics: Anticoagulants; Arterial Occlusive Diseases; Arteries; Blood Coagulation; Blood Coagulation Factors;

2011

Trials

9 trials available for dalteparin and Arterial Obstructive Diseases

ArticleYear
Low-molecular-weight heparin versus aspirin for acute ischemic stroke with large artery occlusive disease: subgroup analyses from the Fraxiparin in Stroke Study for the treatment of ischemic stroke (FISS-tris) study.
    Stroke, 2012, Volume: 43, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arterial Occlusive Diseases; As

2012
Low-molecular-weight heparin compared with aspirin for the treatment of acute ischaemic stroke in Asian patients with large artery occlusive disease: a randomised study.
    The Lancet. Neurology, 2007, Volume: 6, Issue:5

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anticoagulants; Arterial Occlusive Diseases; A

2007
Potential use of a low-molecular-weight heparin to prevent restenosis in patients with extensive wall damage following peripheral angioplasty.
    Angiology, 2001, Volume: 52, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon; Anticoagulants; Arterial Occlusive

2001
Comparison of enoxaparin and unfractionated heparin in endovascular interventions for the treatment of peripheral arterial occlusive disease: a randomized controlled trial.
    Journal of thrombosis and haemostasis : JTH, 2011, Volume: 9, Issue:11

    Topics: Aged; Arterial Occlusive Diseases; Aspirin; Drug Therapy, Combination; Endothelium, Vascular; Enoxap

2011
Low-molecular-weight heparin in arterial reconstructive surgery: a double-blind, randomized dose-finding trial.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2002, Volume: 8, Issue:4

    Topics: Aged; Anticoagulants; Arterial Occlusive Diseases; Blood Vessel Prosthesis Implantation; Dose-Respon

2002
[Dose-dependent decrease of the rate of restenosis of stents in peripheral vessels with reviparin].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1999, Volume: 170, Issue:1

    Topics: Aged; Angiography, Digital Subtraction; Anticoagulants; Arterial Occlusive Diseases; Dose-Response R

1999
Effect of dalteparin on healing of chronic foot ulcers in diabetic patients with peripheral arterial occlusive disease: a prospective, randomized, double-blind, placebo-controlled study.
    Diabetes care, 2003, Volume: 26, Issue:9

    Topics: Age of Onset; Aged; Aged, 80 and over; Arterial Occlusive Diseases; Body Mass Index; Dalteparin; Dia

2003
Single-arm study of bridging therapy with low-molecular-weight heparin for patients at risk of arterial embolism who require temporary interruption of warfarin.
    Circulation, 2004, Sep-21, Volume: 110, Issue:12

    Topics: Anticoagulants; Arterial Occlusive Diseases; Aspirin; Atrial Fibrillation; Blood Loss, Surgical; Coh

2004
Low-molecular-weight heparin for prevention of restenosis after femoropopliteal percutaneous transluminal angioplasty: a randomized controlled trial.
    Journal of vascular surgery, 2006, Volume: 44, Issue:6

    Topics: Aged; Angioplasty, Balloon; Arterial Occlusive Diseases; Aspirin; Dalteparin; Drug Therapy, Combinat

2006

Other Studies

17 other studies available for dalteparin and Arterial Obstructive Diseases

ArticleYear
Low-molecular-weight heparin in atherosclerotic stroke: a surprising resurrection of anticoagulants?
    Stroke, 2012, Volume: 43, Issue:2

    Topics: Antifibrinolytic Agents; Arterial Occlusive Diseases; Aspirin; Brain Ischemia; Female; Humans; Intra

2012
Cocaine-related peripheral vascular occlusive disease treated with iloprost in addition to anticoagulants and antibiotics.
    Clinical toxicology (Philadelphia, Pa.), 2007, Volume: 45, Issue:1

    Topics: Acute Disease; Adult; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anticoag

2007
A Patient-Tailored Approach to Management of Acute Limb Ischemia in Patients with COVID-19: A Case Series.
    The American journal of case reports, 2022, Feb-07, Volume: 23

    Topics: Adult; Aged; Arterial Occlusive Diseases; COVID-19; Enoxaparin; Female; Humans; Ischemia; Male; Midd

2022
Acute ophthalmic artery occlusion in a COVID-19 patient on apixaban.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2020, Volume: 29, Issue:8

    Topics: Arterial Occlusive Diseases; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatm

2020
The Use of Low-Dose Recombinant Tissue Plasminogen Activator to Treat a Preterm Infant with an Intrauterine Spontaneous Arterial Thromboembolism.
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2015, Volume: 32, Issue:4

    Topics: Arterial Occlusive Diseases; Brachial Artery; Dose-Response Relationship, Drug; Drug Therapy, Combin

2015
Presumed bilateral cilioretinal artery occlusion related to relapsing white dot syndrome.
    European journal of ophthalmology, 2016, Aug-04, Volume: 26, Issue:5

    Topics: Arterial Occlusive Diseases; Aspirin; Ciliary Arteries; Coloring Agents; Drug Therapy, Combination;

2016
[Substantiation of the system of thrombus formation prevention in treatment of patients with hip joint pathology against the background of arterial insufficiency of the lower extremities].
    Khirurgiia, 2016, Issue:5

    Topics: Aged; Anticoagulants; Arterial Occlusive Diseases; Arthroplasty, Replacement, Hip; Blood Coagulation

2016
Medical Management of Extensive Arterial Thromboembolism in a Patient with Essential Thrombocythemia and Warfarin Failure.
    Annals of vascular surgery, 2017, Volume: 42

    Topics: Anticoagulants; Arterial Occlusive Diseases; Blood Coagulation; Blood Coagulation Tests; Computed To

2017
Effectiveness of enoxaparin for prevention of radial artery occlusion after transradial cardiac catheterization.
    Journal of thrombosis and thrombolysis, 2010, Volume: 29, Issue:3

    Topics: Arterial Occlusive Diseases; Cardiac Catheterization; Enoxaparin; Female; Follow-Up Studies; Humans;

2010
Radiocephalic fistula complicated by distal ischemia: treatment by ulnar artery dilatation.
    Cardiovascular and interventional radiology, 2010, Volume: 33, Issue:1

    Topics: Aged; Angioplasty, Balloon; Arterial Occlusive Diseases; Catheters, Indwelling; Clopidogrel; Diabete

2010
Fatal basilar artery occlusion under dabigatran occurring 13 days after femoral embolectomy.
    Vascular and endovascular surgery, 2012, Volume: 46, Issue:4

    Topics: Aged; Anticoagulants; Antithrombins; Arterial Occlusive Diseases; Atrial Fibrillation; Benzimidazole

2012
Effectiveness of low-dose prolonged infusion of tissue plasminogen activator in a nonagenarian patient with acute pulmonary embolism and main pulmonary artery thrombus.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2013, Volume: 24, Issue:1

    Topics: Acute Disease; Aged, 80 and over; Anticoagulants; Arterial Occlusive Diseases; Drug Substitution; Em

2013
A case of warfarin skin necrosis despite enoxaparin anticoagulation in a patient with protein S deficiency.
    Annals of vascular surgery, 2004, Volume: 18, Issue:2

    Topics: Anticoagulants; Arterial Occlusive Diseases; Enoxaparin; Female; Fibrinolytic Agents; Heparin, Low-M

2004
Cerebral subarachnoid blood migration consecutive to a lumbar haematoma after spinal anaesthesia.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:7

    Topics: Aged; Anesthesia, Spinal; Anesthetics, Intravenous; Anesthetics, Local; Angioplasty, Balloon; Arteri

2008
ADAMTS13 and von Willebrand factor concentrations in patients with diabetes mellitus.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2009, Volume: 20, Issue:8

    Topics: ADAM Proteins; ADAMTS13 Protein; Adult; Aged; Aged, 80 and over; Arterial Occlusive Diseases; Case-C

2009
Sevuparin binds to multiple adhesive ligands and reduces sickle red blood cell-induced vaso-occlusion.
    British journal of haematology, 2016, Volume: 175, Issue:5

    Topics: Anemia, Sickle Cell; Animals; Arterial Occlusive Diseases; Cell Adhesion; Cells, Cultured; Endotheli

2016
Recurrent arterial thromboses in a woman with heparin induced thrombocytopenia, successfully managed with iloprost followed by clopidogrel. An alternative therapeutic option for heparin induced thrombocytopenia type II syndrome.
    International angiology : a journal of the International Union of Angiology, 2006, Volume: 25, Issue:1

    Topics: Aged; Arterial Occlusive Diseases; Clopidogrel; Drug Therapy, Combination; Female; Fibrinolytic Agen

2006