Page last updated: 2024-10-18

dalteparin and Anti-Phospholipid Antibody Syndrome

dalteparin has been researched along with Anti-Phospholipid Antibody Syndrome in 63 studies

Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)

Research Excerpts

ExcerptRelevanceReference
"To evaluate the efficacy and safety of anticoagulant agents, such as aspirin and heparin, in women with a history of at least two unexplained miscarriages with or without inherited thrombophilia."8.90Aspirin and/or heparin for women with unexplained recurrent miscarriage with or without inherited thrombophilia. ( de Jong, PG; Di Nisio, M; Goddijn, M; Kaandorp, S; Middeldorp, S, 2014)
"The present study suggests that pravastatin may improve pregnancy outcomes in women with refractory obstetric APS when taken at the onset of PE or IUGR until the end of pregnancy."7.83Pravastatin improves pregnancy outcomes in obstetric antiphospholipid syndrome refractory to antithrombotic therapy. ( Dagklis, T; Girardi, G; Lefkou, E; Mamopoulos, A; Rousso, D; Vosnakis, C, 2016)
"The aim of this retrospective, observational study was to determine the impact of low-dose enoxaparin (20 mg) in conjunction with low-dose aspirin on the pregnancy outcome of women with antiphospholipid syndrome and recurrent miscarriage."7.75Treatment of recurrent miscarriage and antiphospholipid syndrome with low-dose enoxaparin and aspirin. ( Li, TC; Makris, M; Metwally, M; Mo, D; Saravelos, S, 2009)
"Stasis ulcers are commonly the result of chronic venous insufficiency."5.31Stasis ulcers refractory to therapy--accelerated healing by treatment with clopidogrel +/- dalteparin: a preliminary report. ( Bick, RL; Scott, RG, 2001)
"To determine whether low molecular weight heparin (LMWH) plus low-dose aspirin (LDA) is comparable in efficacy and safety to unfractionated heparin (UFH) plus LDA in the management of pregnant women with a history of recurrent spontaneous abortion secondary to antiphospholipid syndrome (APS)."5.15Enoxaparin versus unfractionated heparin in the management of recurrent abortion secondary to antiphospholipid syndrome. ( Abdou, AM; Fouda, IM; Fouda, UM; Ramadan, DI; Sayed, AM; Zaki, MM, 2011)
" The women were randomized, using a random numbers table with blocks of 12, to receive either prophylactic dosing of dalteparin or UFH starting either preconceptionally or early in pregnancy."5.11Treatment of antiphospholipid antibody syndrome (APS) in pregnancy: a randomized pilot trial comparing low molecular weight heparin to unfractionated heparin. ( Ballem, PJ; Ensom, MH; Ensworth, S; Houlihan, E; Purkiss, S; Stephenson, MD; Tsang, P, 2004)
"To evaluate the efficacy and safety of anticoagulant agents, such as aspirin and heparin, in women with a history of at least two unexplained miscarriages with or without inherited thrombophilia."4.90Aspirin and/or heparin for women with unexplained recurrent miscarriage with or without inherited thrombophilia. ( de Jong, PG; Di Nisio, M; Goddijn, M; Kaandorp, S; Middeldorp, S, 2014)
" Low dose aspirin should be given to every pregnant woman with antiphospholipid antibodies, with the addition of low molecular weight heparin in those with previous thrombosis, previous fetal death or failure of monotherapy with aspirin."4.85[The antiphospholipid syndrome in the 21st century]. ( Egurbide, MV; Martinez-Berriotxoa, A; Ruiz-Irastorza, G, 2009)
" A case report is detailed of a 28-year-old woman with antiphospholipid syndrome on warfarin for high risk of venous thrombosis who underwent tonsillectomy."4.84Tonsillectomy in the anticoagulated patient. ( Cole, SM; Cupp, CL; Patterson, MB, 2007)
"The present study suggests that pravastatin may improve pregnancy outcomes in women with refractory obstetric APS when taken at the onset of PE or IUGR until the end of pregnancy."3.83Pravastatin improves pregnancy outcomes in obstetric antiphospholipid syndrome refractory to antithrombotic therapy. ( Dagklis, T; Girardi, G; Lefkou, E; Mamopoulos, A; Rousso, D; Vosnakis, C, 2016)
" She is currently on warfarin, with which she has been adequately controlled most of the time, presenting with only one haemorrhagic event consisting of haematuria and prolonged international normalised ratio (INR) without bleeding."3.81Variability in the international normalised ratio (INR) in patients with antiphospholipid syndrome and positive lupus anticoagulant: should the INR targets be higher? ( Baquero-Salamanca, M; Calderon-Ospina, C; Téllez-Arévalo, AM, 2015)
"The aim of this retrospective, observational study was to determine the impact of low-dose enoxaparin (20 mg) in conjunction with low-dose aspirin on the pregnancy outcome of women with antiphospholipid syndrome and recurrent miscarriage."3.75Treatment of recurrent miscarriage and antiphospholipid syndrome with low-dose enoxaparin and aspirin. ( Li, TC; Makris, M; Metwally, M; Mo, D; Saravelos, S, 2009)
" Aspirin, 75 mg daily was given in addition to enoxaparin to women with antiphospholipid syndrome."3.70Gestational outcome in thrombophilic women with recurrent pregnancy loss treated by enoxaparin. ( Blumenfeld, Z; Brenner, B; Hoffman, R; Weiner, Z; Younis, JS, 2000)
"The antiphospholipid syndrome is described with a review of its historical development as a recognized syndrome, what constitutes an antiphospholipid antibody, how it is measured, and how the syndrome is treated."2.43The antiphospholipid syndrome: what are we really measuring? How do we measure it? And how do we treat it? ( Ortel, TL, 2006)
"Antiphospholipid syndrome is an autoimmune disease characterized by vascular thrombosis involving both the arterial and venous systems that can lead to tissue ischemia or end-organ damage."1.51The Solitary Blue Toe: A Unique Presentation of Antiphospholipid Syndrome. ( Dimond, DG; Driscoll, K; Kiser, C; Lam, JK; Razzante, M; Wurster, L, 2019)
": Lupus anticoagulant hypoprothrombinemia syndrome (LAHS) is a rare disorder characterized by development of lupus anticoagulant and antiprothrombin antibodies."1.48Fatal pulmonary embolism and pulmonary hemorrhage in lupus anticoagulant hypoprothrombinemia syndrome: a case report and review of literature. ( Chen, X; Cunningham, MT; Nedved, D; Plapp, FV, 2018)
"One patient had deep venous thrombosis in the 6 weeks postpartum, in the GROUP P."1.46Is a therapeutic anticoagulation window needed for delivery when using prophylactic low molecular weight heparin during pregnancy? A retrospective monocentric study. ( Agman, A; Amsellem, J; Cesario, E; Nizard, J; Roueli, A; Vauthier-Brouzes, D, 2017)
"The antiphospholipid antibody syndrome is defined by the presence of antiphospholipid antibodies in patients with recurrent venous or arterial thromboembolism (1)."1.43Antiphospholipid Syndrome with Antiβ2glicoprotein-1 Antibodies as the Cause of Recurrent Tibial Vein Thrombosis in SAPHO syndrome. ( Brzosko, M; Przepiera-Będzak, H, 2016)
" Thrombotic storm was defined as newly diagnosed multisite venous thromboembolism (VTE) with acute thrombus progression despite conventional or higher than conventional dosing of heparin or low molecular weight heparin."1.38Treatment, survival, and thromboembolic outcomes of thrombotic storm in children. ( Gibson, E; Goldenberg, NA; Knoll, CM; Manco-Johnson, MJ; Mourani, PM; Soep, J; Wang, M, 2012)
"It led to a complete resolution of the thrombus in 4 weeks without the need for a high-risk operation in this patient."1.35Cardioverter-defibrillator lead-related thrombus treated with prolonged anticoagulation in patient with prothrombotic disorder. ( Chojnowska, L; Hoffman, P; Klopotowski, M; Konka, M; Maczynska, R; Malek, LA; Ruzyllo, W; Skwarek, M, 2008)
" The results of this study indicate that nadroparin alone is useful and safe in the management of pregnant patients with APS."1.33Efficacy and safety of nadroparin in the treatment of pregnant women with antiphospholipid syndrome: a prospective cohort study. ( Chiarelli, S; De Silvestro, G; Fais, G; Favaro, M; Pengo, V; Ruffatti, A; Suma, V; Todesco, S; Tonello, M, 2005)
"We suppose that cocaine abuse may have had a delayed effect as trigger of acute myocardial infarction."1.33Acute myocardial infarction in a young woman with antiphospholipid syndrome and occasional cocaine abuse. ( Dei Cas, L; Pedrinazzi, C; Procopio, R; Raddino, R; Zanini, G, 2005)
"Hypercoaguable states such as the antiphospholipid antibody syndrome may be associated with thromboses in any vascular bed."1.33Budd-Chiari syndrome, systemic lupus erythematosus, and secondary antiphospholipid antibody syndrome in pregnancy. ( Aisenbrey, GA; Argubright, KF; Joffe, GM, 2005)
" In this report, we describe a woman with primary antiphospholipid antibody syndrome who developed extensive pulmonary embolism despite receiving a proven therapeutic dosage of low molecular weight heparin."1.31Low-molecular weight heparin: treatment failure in a patient with primary antiphospholipid antibody syndrome. ( Ahmed, S; Karim, A; Mattana, J; Patel, D; Siddiqui, R, 2002)
"Stasis ulcers are commonly the result of chronic venous insufficiency."1.31Stasis ulcers refractory to therapy--accelerated healing by treatment with clopidogrel +/- dalteparin: a preliminary report. ( Bick, RL; Scott, RG, 2001)

Research

Studies (63)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (4.76)18.2507
2000's33 (52.38)29.6817
2010's26 (41.27)24.3611
2020's1 (1.59)2.80

Authors

AuthorsStudies
de Jong, PG1
Kaandorp, S1
Di Nisio, M1
Goddijn, M1
Middeldorp, S1
Frank, M1
Sodin-Semrl, S1
Rozman, B1
Potocnik, M1
Kralj-Iglic, V1
Makatsaria, AD1
Bitsadze, VO1
Dolgushina, NV1
Ruffatti, A2
Favaro, M2
Tonello, M2
De Silvestro, G2
Pengo, V2
Fais, G1
Suma, V1
Chiarelli, S1
Todesco, S1
Marson, P1
Bortolati, M1
Minucci, D1
Stojanovich, L1
Mikovic, Z1
Mandic, V1
Popovich-Kuzmanovich, D1
Perunicic, J1
Antonijevic, NM1
Miljic, P1
Djordjevic, V1
Mikovic, D1
Kovac, M1
Djokic, M1
Mrdovic, I1
Nikolic, A1
Vasiljevic, Z1
Arnout, J1
Spitz, B1
Wittevrongel, C1
Vanrusselt, M1
Van Assche, A1
Vermylen, J1
Karag'ozova, Zh1
Chernev, T1
Iankova, Z1
Baleva, M1
Dimitrov, A1
Alalaf, S1
Dabas, G1
De, D1
Handa, S1
Aggarwal, D1
Sudhakar, D1
Kamran, H1
Chen, N1
Mims, M1
Hamzeh, I1
Roueli, A1
Cesario, E1
Amsellem, J1
Agman, A1
Vauthier-Brouzes, D1
Nizard, J1
Chen, X1
Nedved, D1
Plapp, FV1
Cunningham, MT1
Dimond, DG1
Lam, JK1
Wurster, L1
Kiser, C1
Driscoll, K1
Razzante, M1
Roie, EV1
Labarque, V1
Renard, M1
Van Geet, C1
Gabriëls, L1
Bouvier, S1
Cochery-Nouvellon, E1
Lavigne-Lissalde, G1
Mercier, E1
Marchetti, T1
Balducchi, JP2
Marès, P2
Gris, JC2
Baquero-Salamanca, M1
Téllez-Arévalo, AM1
Calderon-Ospina, C1
Vargas-Hitos, JA1
Sabio, JM1
Navarrete-Navarrete, N1
Zamora-Pasadas, M1
Jiménez-Alonso, J1
Ismail, AM1
Hamed, AH1
Saso, S1
Abu-Elhasan, AM1
Abu-Elghar, MM1
Abdelmeged, AN1
Maalouly, G1
Ward, C1
Smayra, V1
Saliba, Y1
Aftimos, G1
Haddad, F1
Farès, N1
Lefkou, E1
Mamopoulos, A1
Dagklis, T1
Vosnakis, C1
Rousso, D1
Girardi, G1
Przepiera-Będzak, H1
Brzosko, M1
Alijotas-Reig, J2
Casellas-Caro, M1
Ferrer-Oliveras, R1
Llurba-Olive, E1
Hermosilla, E1
Vilardell-Tarres, M1
Cabero-Roura, L1
Forsnes, E1
Occhino, A1
Acosta, R1
Ruiz-Irastorza, G1
Martinez-Berriotxoa, A1
Egurbide, MV1
Mo, D1
Saravelos, S1
Metwally, M1
Makris, M1
Li, TC1
Dönmez, O1
Durmaz, O1
Fouda, UM2
Sayed, AM2
Ramadan, DI2
Fouda, IM2
Abdou, AM1
Zaki, MM1
Karow, A1
Hainmann, I1
Nakamura, L1
Budde, U1
Mueller, C1
Zieger, B1
Listernick, R1
D'Ippolito, S1
Marana, R1
Di Nicuolo, F1
Castellani, R1
Veglia, M1
Stinson, J1
Scambia, G1
Di Simone, N1
Manco-Johnson, MJ1
Wang, M1
Goldenberg, NA1
Soep, J1
Gibson, E1
Knoll, CM1
Mourani, PM1
Yazbek, MA1
Velho, P1
Nadruz, W1
Mahayri, N1
Appenzeller, S1
Costallat, LT1
Turaka, K1
Bryan, JS1
Kwong, HM1
Ziemianski, MC1
Ahmed, S1
Karim, A1
Patel, D1
Siddiqui, R1
Mattana, J1
Ferrer-Raventos, JC1
Kozlovskaia, NL1
Shakhnova, EA1
Kushnir, VV1
Shilov, EM1
Raddino, R1
Pedrinazzi, C1
Zanini, G1
Procopio, R1
Dei Cas, L1
Joffe, GM1
Aisenbrey, GA1
Argubright, KF1
Ortel, TL1
Elchalal, U1
Gabbay, E1
Nadjari, M1
Varon, D1
Zelig, O1
Ben-Chetrit, E1
Cole, SM1
Patterson, MB1
Cupp, CL1
Di Gennaro, L1
Maggi, F1
Novarese, L1
Cipriani, MC1
Bonomo, L1
Landolfi, R1
Bick, RL2
Many, A3
Tanne, D1
Katzav, A1
Beilin, O1
Grigoriadis, NC1
Blank, M1
Pick, CG1
Landenberg, Pv1
Shoenfeld, Y1
Chapman, J1
Malek, LA1
Chojnowska, L1
Konka, M1
Klopotowski, M1
Skwarek, M1
Maczynska, R1
Hoffman, P1
Ruzyllo, W1
Dulitzki, M2
Pauzner, R2
Langevitz, P2
Pras, M1
Schiff, E1
Brenner, B1
Hoffman, R1
Blumenfeld, Z1
Weiner, Z1
Younis, JS1
Marietta, M1
Bertesi, M1
Simoni, L1
Castelli, I1
Cappi, C1
Torelli, G1
Livneh, A1
Kenett, R1
Quéré, I1
Hoffet, M1
Thachil, J1
Dey, M1
Charles Bates, A1
McMillan, P1
Ebina, Y1
Yamada, H1
Kato, EH1
Yamamoto, R1
Sakuragi, N1
Fujimoto, S1
Stone, S1
Hunt, BJ1
Seed, PT1
Parmar, K1
Khamashta, MA1
Poston, L1
Stephenson, MD1
Ballem, PJ1
Tsang, P1
Purkiss, S1
Ensworth, S1
Houlihan, E1
Ensom, MH1
Korenkov, M1
Depta, A1
Kentner, R1
Beck, J1
Junginger, T1
Shefras, J1
Farquharson, RG1
Scott, RG1
Villié, P1
Noël, N1
Ackermann, F1
Rivoisy, C1
Le Pavec, J1
Savale, L1
Goujard, C1
Rocher, L1
Lambotte, O1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Hydroxychloroquine in Unexplained Recurrent Pregnancy Loss ,Double Blinded Randomized Controlled Trial .[NCT05237843]Phase 170 participants (Anticipated)Interventional2022-03-01Not yet recruiting
A Randomized Clinical Trial of Using Preconceptional Enoxaparin AND Low Dose Aspirin 81mg in Patient With Antiphospholipid Syndrome(APS)[NCT01661439]316 participants (Anticipated)Observational2012-03-31Recruiting
Low-molecular-weight Heparin Versus Unfractionated Heparin in Pregnant Women With History of Recurrent Abortion Secondary to Antiphospholipid Syndrome. A Randomized Controlled Trial[NCT01051778]Phase 260 participants (Actual)Interventional2006-06-30Completed
Genetics of Antiphospholipid Antibody Syndrome[NCT00482794]2,800 participants (Anticipated)Observational2006-06-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Live Birth Rate = (Number of Live Births / Total Number of Pregnancies)

Live birth occurs when a fetus (> 24 weeks ) , exits the maternal body and subsequently shows signs of life, such as voluntary movement, heartbeat, or pulsation of the umbilical cord. (NCT01051778)
Timeframe: pregnancy > 24weeks gestation

InterventionPercentage of pregnancies (Number)
Enoxaparin 40 mg /Day Plus Low Dose Aspirin24
Heparin Calcium 5,000 U Twice Daily Plus Low Dose Aspirin20

Reviews

9 reviews available for dalteparin and Anti-Phospholipid Antibody Syndrome

ArticleYear
Aspirin and/or heparin for women with unexplained recurrent miscarriage with or without inherited thrombophilia.
    The Cochrane database of systematic reviews, 2014, Jul-04, Issue:7

    Topics: Abortion, Habitual; Anticoagulants; Antiphospholipid Syndrome; Aspirin; Enoxaparin; Female; Heparin,

2014
Use of the low-molecular-weight heparin nadroparin during pregnancy. A review.
    Current medical research and opinion, 2003, Volume: 19, Issue:1

    Topics: Antiphospholipid Syndrome; Female; Fibrinolytic Agents; Heart Valve Prosthesis; Herpes Simplex; Huma

2003
Plasma exchange in the management of high risk pregnant patients with primary antiphospholipid syndrome. A report of 9 cases and a review of the literature.
    Autoimmunity reviews, 2007, Volume: 6, Issue:3

    Topics: Adult; Anticoagulants; Antiphospholipid Syndrome; Female; Humans; Immunoglobulins, Intravenous; Nadr

2007
[Application of low-molecular-weight heparin during pregnancy and delivery in case of reproductive failure due to antiphospholipid syndrome].
    Akusherstvo i ginekologiia, 2000, Volume: 39, Issue:3

    Topics: Adult; Antiphospholipid Syndrome; Blood Coagulation; Cesarean Section; Female; Heparin, Low-Molecula

2000
[The antiphospholipid syndrome in the 21st century].
    Medicina clinica, 2009, Sep-19, Volume: 133, Issue:10

    Topics: Adult; Antibodies, Anticardiolipin; Anticoagulants; Antiphospholipid Syndrome; Aspirin; Clinical Tri

2009
The antiphospholipid syndrome: what are we really measuring? How do we measure it? And how do we treat it?
    Journal of thrombosis and thrombolysis, 2006, Volume: 21, Issue:1

    Topics: Aged; Antibodies, Antiphospholipid; Anticoagulants; Antiphospholipid Syndrome; beta 2-Glycoprotein I

2006
Tonsillectomy in the anticoagulated patient.
    The Annals of otology, rhinology, and laryngology, 2007, Volume: 116, Issue:8

    Topics: Adult; Algorithms; Anticoagulants; Antiphospholipid Syndrome; Blood Loss, Surgical; Dose-Response Re

2007
Antiphospholipid syndrome in pregnancy.
    Hematology/oncology clinics of North America, 2008, Volume: 22, Issue:1

    Topics: Abortion, Habitual; Antibodies, Antiphospholipid; Anticoagulants; Antiphospholipid Syndrome; Aspirin

2008
Life-threatening Hughes-Stovin syndrome: The Yin and Yang of anticoagulation therapy.
    Joint bone spine, 2016, Volume: 83, Issue:4

    Topics: Adrenal Cortex Hormones; Adult; Anticoagulants; Antiphospholipid Syndrome; Behcet Syndrome; Critical

2016

Trials

7 trials available for dalteparin and Anti-Phospholipid Antibody Syndrome

ArticleYear
Bemiparin versus low dose aspirin for management of recurrent early pregnancy losses due to antiphospholipd antibody syndrome.
    Archives of gynecology and obstetrics, 2012, Volume: 285, Issue:3

    Topics: Abortion, Habitual; Adult; Antiphospholipid Syndrome; Aspirin; Embryo Loss; Female; Heparin, Low-Mol

2012
Randomized controlled study of pre-conception thromboprophylaxis among patients with recurrent spontaneous abortion related to antiphospholipid syndrome.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2016, Volume: 132, Issue:2

    Topics: Abortion, Habitual; Adult; Antiphospholipid Syndrome; Aspirin; Drug Therapy, Combination; Egypt; Eno

2016
Efficacy and safety of two doses of low molecular weight heparin (enoxaparin) in pregnant women with a history of recurrent abortion secondary to antiphospholipid syndrome.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2010, Volume: 30, Issue:8

    Topics: Abortion, Habitual; Adult; Anticoagulants; Antiphospholipid Syndrome; Enoxaparin; Female; Humans; In

2010
Enoxaparin versus unfractionated heparin in the management of recurrent abortion secondary to antiphospholipid syndrome.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2011, Volume: 112, Issue:3

    Topics: Abortion, Habitual; Adult; Antibodies, Antiphospholipid; Anticoagulants; Antiphospholipid Syndrome;

2011
Low molecular weight heparin and warfarin in the treatment of patients with antiphospholipid syndrome during pregnancy.
    Thrombosis and haemostasis, 2001, Volume: 86, Issue:6

    Topics: Abnormalities, Drug-Induced; Adult; Anticoagulants; Antiphospholipid Syndrome; Aspirin; Autoimmune D

2001
Enoxaparin sodium improves pregnancy outcome in aspirin-resistant antiphospholipid/antiprotein antibody syndromes.
    Thrombosis and haemostasis, 2002, Volume: 87, Issue:3

    Topics: Abortion, Habitual; Anticoagulants; Antiphospholipid Syndrome; Aspirin; Drug Resistance; Enoxaparin;

2002
Treatment of antiphospholipid antibody syndrome (APS) in pregnancy: a randomized pilot trial comparing low molecular weight heparin to unfractionated heparin.
    Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2004, Volume: 26, Issue:8

    Topics: Adult; Anticoagulants; Antiphospholipid Syndrome; Aspirin; Dalteparin; Female; Heparin; Humans; Pilo

2004

Other Studies

47 other studies available for dalteparin and Anti-Phospholipid Antibody Syndrome

ArticleYear
Effects of low-molecular-weight heparin on adhesion and vesiculation of phospholipid membranes: a possible mechanism for the treatment of hypercoagulability in antiphospholipid syndrome.
    Annals of the New York Academy of Sciences, 2009, Volume: 1173

    Topics: Adsorption; Antibodies, Monoclonal; Anticoagulants; Antiphospholipid Syndrome; Autoantibodies; beta

2009
Efficacy and safety of nadroparin in the treatment of pregnant women with antiphospholipid syndrome: a prospective cohort study.
    Lupus, 2005, Volume: 14, Issue:2

    Topics: Adult; Antibodies, Antiphospholipid; Anticoagulants; Antiphospholipid Syndrome; Female; Follow-Up St

2005
Treatment of antiphospholipid syndrome in pregnancy with low doses of intravenous immunoglobulin.
    The Israel Medical Association journal : IMAJ, 2007, Volume: 9, Issue:7

    Topics: Adult; Anti-Inflammatory Agents; Antiphospholipid Syndrome; Autoantibodies; Dexamethasone; Dose-Resp

2007
Clinical challenge: heparin-induced thrombocytopenia type II (HIT II) or pseudo-HIT in a patient with antiphospholipid syndrome.
    Journal of thrombosis and thrombolysis, 2008, Volume: 26, Issue:2

    Topics: Administration, Oral; Adult; Antibodies; Anticoagulants; Antiphospholipid Syndrome; Diagnosis, Diffe

2008
High-dose intravenous immunoglobulin treatment of a pregnant patient with an antiphospholipid syndrome: immunological changes associated with a successful outcome.
    Thrombosis and haemostasis, 1994, Volume: 71, Issue:6

    Topics: Adult; Antibodies, Anti-Idiotypic; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Aspirin;

1994
Delayed-type hypersensitivity reaction to enoxaparin in a pregnant woman.
    Postgraduate medical journal, 2019, Volume: 95, Issue:1127

    Topics: Adult; Anticoagulants; Antiphospholipid Syndrome; Enoxaparin; Female; Humans; Hypersensitivity, Dela

2019
A Sticky Situation: Aortic Valve Thrombus in Patient with Antiphospholipid Antibody Syndrome and Immune Thrombocytopenia.
    The American journal of medicine, 2020, Volume: 133, Issue:8

    Topics: Adult; Anticoagulants; Antiphospholipid Syndrome; Aortic Valve; Aortic Valve Stenosis; Benzoates; Bi

2020
Is a therapeutic anticoagulation window needed for delivery when using prophylactic low molecular weight heparin during pregnancy? A retrospective monocentric study.
    European journal of obstetrics, gynecology, and reproductive biology, 2017, Volume: 215

    Topics: Adult; Anticoagulants; Antiphospholipid Syndrome; Delivery, Obstetric; Enoxaparin; Female; Heparin,

2017
Fatal pulmonary embolism and pulmonary hemorrhage in lupus anticoagulant hypoprothrombinemia syndrome: a case report and review of literature.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2018, Volume: 29, Issue:8

    Topics: Aged; Anticoagulants; Antiphospholipid Syndrome; Enoxaparin; Fatal Outcome; Female; Gastrointestinal

2018
The Solitary Blue Toe: A Unique Presentation of Antiphospholipid Syndrome.
    Journal of the American Podiatric Medical Association, 2019, Volume: 109, Issue:3

    Topics: Antibodies, Antiphospholipid; Anticoagulants; Antiphospholipid Syndrome; Blue Toe Syndrome; Computed

2019
Obsessive-compulsive behavior as presenting symptom of primary antiphospholipid syndrome.
    Psychosomatic medicine, 2013, Volume: 75, Issue:3

    Topics: Adolescent; Anticoagulants; Antiphospholipid Syndrome; Caudate Nucleus; Diagnosis, Differential; Eno

2013
Comparative incidence of pregnancy outcomes in treated obstetric antiphospholipid syndrome: the NOH-APS observational study.
    Blood, 2014, Jan-16, Volume: 123, Issue:3

    Topics: Abortion, Habitual; Abortion, Spontaneous; Adolescent; Adult; Antibodies, Anticardiolipin; Antibodie

2014
Variability in the international normalised ratio (INR) in patients with antiphospholipid syndrome and positive lupus anticoagulant: should the INR targets be higher?
    BMJ case reports, 2015, Apr-09, Volume: 2015

    Topics: Adult; Anticoagulants; Antiphospholipid Syndrome; Enoxaparin; Female; Hematuria; Hemorrhage; Humans;

2015
Severe digital necrosis as the clinical onset of antiphospholipid syndrome.
    Internal and emergency medicine, 2016, Volume: 11, Issue:5

    Topics: Aged; Antiphospholipid Syndrome; Enoxaparin; Fibrinolytic Agents; Humans; Male; Necrosis

2016
Fish oil attenuates neurologic severity of antiphospholipid syndrome in a mice experimental model.
    Nutritional neuroscience, 2017, Volume: 20, Issue:10

    Topics: Animals; Antiphospholipid Syndrome; Anxiety; Behavior, Animal; Brain; Curcumin; Disease Models, Anim

2017
Pravastatin improves pregnancy outcomes in obstetric antiphospholipid syndrome refractory to antithrombotic therapy.
    The Journal of clinical investigation, 2016, 08-01, Volume: 126, Issue:8

    Topics: Adult; Antiphospholipid Syndrome; Endothelium; Enoxaparin; Female; Fibrinolytic Agents; Gestational

2016
Antiphospholipid Syndrome with Antiβ2glicoprotein-1 Antibodies as the Cause of Recurrent Tibial Vein Thrombosis in SAPHO syndrome.
    Acta dermatovenerologica Croatica : ADC, 2016, Volume: 24, Issue:4

    Topics: Acquired Hyperostosis Syndrome; Adult; Antibodies, Anticardiolipin; Antiphospholipid Syndrome; Enoxa

2016
Are anti-beta-glycoprotein-I antibodies markers for recurrent pregnancy loss in lupus anticoagulant/anticardiolipin seronegative women?
    American journal of reproductive immunology (New York, N.Y. : 1989), 2008, Volume: 60, Issue:3

    Topics: Abortion, Habitual; Adult; Antibodies, Anticardiolipin; Antibodies, Antiphospholipid; Anticoagulants

2008
Spontaneous spinal epidural hematoma in pregnancy associated with using low molecular weight heparin.
    Obstetrics and gynecology, 2009, Volume: 113, Issue:2 Pt 2

    Topics: Adult; Anticoagulants; Antiphospholipid Syndrome; Cesarean Section; Enoxaparin; Female; Hematoma, Ep

2009
Treatment of recurrent miscarriage and antiphospholipid syndrome with low-dose enoxaparin and aspirin.
    Reproductive biomedicine online, 2009, Volume: 19, Issue:2

    Topics: Abortion, Habitual; Adult; Anticoagulants; Antiphospholipid Syndrome; Aspirin; Dose-Response Relatio

2009
Calcinosis cutis universalis with pediatric systemic lupus erythematosus.
    Pediatric nephrology (Berlin, Germany), 2010, Volume: 25, Issue:7

    Topics: Administration, Oral; Antiphospholipid Syndrome; Aspirin; Calcinosis; Child; Cyclosporine; Dermatolo

2010
Progressive thrombosis in a 13-year-old girl with trisomy 21 under therapy with low molecular weight heparin.
    Klinische Padiatrie, 2011, Volume: 223, Issue:3

    Topics: Adolescent; Antibodies, Antiphospholipid; Anticoagulants; Antiphospholipid Syndrome; Antithrombins;

2011
A 15-year-old girl with hypertension.
    Pediatric annals, 2011, Volume: 40, Issue:5

    Topics: Adolescent; Anticoagulants; Antiphospholipid Syndrome; Cerebral Infarction; Enoxaparin; Female; Huma

2011
Effect of Low Molecular Weight Heparins (LMWHs) on antiphospholipid Antibodies (aPL)-mediated inhibition of endometrial angiogenesis.
    PloS one, 2012, Volume: 7, Issue:1

    Topics: Adult; Animals; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Dose-Response Relationship,

2012
Treatment, survival, and thromboembolic outcomes of thrombotic storm in children.
    The Journal of pediatrics, 2012, Volume: 161, Issue:4

    Topics: Adolescent; Anticoagulants; Antiphospholipid Syndrome; Child; Child, Preschool; Cytokines; Enoxapari

2012
Extensive skin necrosis induced by low-molecular-weight heparin in a patient with systemic lupus erythematosus and antiphospholipid syndrome.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2012, Volume: 18, Issue:4

    Topics: Antiphospholipid Syndrome; Aspirin; Drug Eruptions; Drug Therapy, Combination; Enoxaparin; Female; F

2012
Bilateral occlusive retinal vasculitis in a patient with primary antiphospholipid antibody syndrome.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2012, Volume: 47, Issue:6

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Anticoagulants; Antiphospholipid Syndrom

2012
Low-molecular weight heparin: treatment failure in a patient with primary antiphospholipid antibody syndrome.
    The American journal of the medical sciences, 2002, Volume: 324, Issue:5

    Topics: Adolescent; Anticoagulants; Antiphospholipid Syndrome; Arginine; Arm; Enoxaparin; Female; Folic Acid

2002
Life-threatening bleeding, pregnancy and lupus anticoagulant: success after steroid and anticoagulant therapy.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2004, Volume: 52, Issue:2

    Topics: Adult; Antiphospholipid Syndrome; Aspirin; Enoxaparin; Female; Fibrinolytic Agents; Glucocorticoids;

2004
[Low-molecular heparins in the treatment of APS-nephropathy in primary and secondary antiphospholipid syndrome].
    Terapevticheskii arkhiv, 2004, Volume: 76, Issue:9

    Topics: Adult; Anticoagulants; Antiphospholipid Syndrome; Case-Control Studies; Enoxaparin; Female; Humans;

2004
Acute myocardial infarction in a young woman with antiphospholipid syndrome and occasional cocaine abuse.
    International journal of cardiology, 2005, Nov-02, Volume: 105, Issue:2

    Topics: Adult; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Cocaine-Related Disorders; Coronary

2005
Budd-Chiari syndrome, systemic lupus erythematosus, and secondary antiphospholipid antibody syndrome in pregnancy.
    Obstetrics and gynecology, 2005, Volume: 106, Issue:5 Pt 2

    Topics: Adult; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Budd-Chiari Syndrome; Cholecystectom

2005
Catastrophic antiphospholipid syndrome in the second trimester of pregnancy.
    The Israel Medical Association journal : IMAJ, 2006, Volume: 8, Issue:12

    Topics: Abortion, Induced; Adult; Anti-Inflammatory Agents; Anticoagulants; Antineoplastic Agents, Hormonal;

2006
Bilateral axillary vein thrombosis in a young patient with lupus anticoagulant and clavicular bone spurs.
    Thrombosis and haemostasis, 2007, Volume: 98, Issue:6

    Topics: Adolescent; Anticoagulants; Antiphospholipid Syndrome; Axillary Vein; Clavicle; Enoxaparin; Humans;

2007
Preventing death in catastrophic antiphospholipid syndrome.
    The Israel Medical Association journal : IMAJ, 2008, Volume: 10, Issue:1

    Topics: Anticoagulants; Antiphospholipid Syndrome; Enoxaparin; Humans; International Normalized Ratio

2008
Interaction of inflammation, thrombosis, aspirin and enoxaparin in CNS experimental antiphospholipid syndrome.
    Neurobiology of disease, 2008, Volume: 30, Issue:1

    Topics: Alprostadil; Analysis of Variance; Animals; Antiphospholipid Syndrome; Aspirin; Behavior, Animal; be

2008
Cardioverter-defibrillator lead-related thrombus treated with prolonged anticoagulation in patient with prothrombotic disorder.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2008, Volume: 19, Issue:4

    Topics: Adult; Anticoagulants; Antiphospholipid Syndrome; Defibrillators, Implantable; Echocardiography; Eno

2008
Low-molecular-weight heparin during pregnancy and delivery: preliminary experience with 41 pregnancies.
    Obstetrics and gynecology, 1996, Volume: 87, Issue:3

    Topics: Adult; Antiphospholipid Syndrome; Enoxaparin; Female; Fibrinolytic Agents; Humans; Labor, Obstetric;

1996
Gestational outcome in thrombophilic women with recurrent pregnancy loss treated by enoxaparin.
    Thrombosis and haemostasis, 2000, Volume: 83, Issue:5

    Topics: 3' Untranslated Regions; Abortion, Habitual; Activated Protein C Resistance; Adult; Anticoagulants;

2000
Cerebral vein thrombosis and lupus anticoagulant antibodies.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2001, Volume: 7, Issue:3

    Topics: Adult; Anticoagulants; Antiphospholipid Syndrome; Autoimmune Diseases; Enoxaparin; Female; Humans; L

2001
Should low molecular weight heparin dosing be based on anti-Xa assays in antiphospholipid syndrome?
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2013, Volume: 24, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Antibodies, Anticardiolipin; Anticoagulants; Antiphospholipid Syndrome

2013
Superior ophthalmic vein thrombosis as an initial manifestation of antiphospholipid syndrome.
    Orbit (Amsterdam, Netherlands), 2013, Volume: 32, Issue:1

    Topics: Adult; Anticoagulants; Antiphospholipid Syndrome; Dalteparin; Drug Therapy, Combination; Exophthalmo

2013
Thromboprophylaxis with low molecular weight heparin in thrombophilia-complicated pregnancy.
    The journal of obstetrics and gynaecology research, 2002, Volume: 28, Issue:5

    Topics: Adult; Anticoagulants; Antiphospholipid Syndrome; Dalteparin; Female; Humans; Pregnancy; Pregnancy C

2002
Longitudinal evaluation of markers of endothelial cell dysfunction and hemostasis in treated antiphospholipid syndrome and in healthy pregnancy.
    American journal of obstetrics and gynecology, 2003, Volume: 188, Issue:2

    Topics: Anticoagulants; Antiphospholipid Syndrome; Aspirin; Biomarkers; Dalteparin; Endothelium, Vascular; F

2003
[Paraneoplastic lupus anticoagulans syndrome].
    Zentralblatt fur Chirurgie, 2005, Volume: 130, Issue:4

    Topics: Anticoagulants; Antiphospholipid Syndrome; Dalteparin; Female; Fibrinolytic Agents; Follow-Up Studie

2005
Bone density studies in pregnant women receiving heparin.
    European journal of obstetrics, gynecology, and reproductive biology, 1996, Volume: 65, Issue:2

    Topics: Anticoagulants; Antiphospholipid Syndrome; Bone Density; Case-Control Studies; Dalteparin; Female; H

1996
Stasis ulcers refractory to therapy--accelerated healing by treatment with clopidogrel +/- dalteparin: a preliminary report.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2001, Volume: 7, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Antiphospholipid Syndrome; Clopidogrel; Dalteparin;

2001