Page last updated: 2024-10-18

dalteparin and Ankle Injuries

dalteparin has been researched along with Ankle Injuries in 5 studies

Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)

Ankle Injuries: Harm or hurt to the ankle or ankle joint usually inflicted by an external source.

Research Excerpts

ExcerptRelevanceReference
" The objective of this study was to evaluate the efficacy of dalteparin during lower-limb immobilization after surgical treatment of Achilles tendon rupture."9.12Prolonged thromboprophylaxis with dalteparin after surgical treatment of achilles tendon rupture: a randomized, placebo-controlled study. ( de Bri, E; Elvin, A; Lapidus, LJ; Lärfars, G; Levander, C; Ponzer, S; Rosfors, S, 2007)
" The objective of this study was to evaluate the efficacy of dalteparin during lower-limb immobilization after surgical treatment of Achilles tendon rupture."5.12Prolonged thromboprophylaxis with dalteparin after surgical treatment of achilles tendon rupture: a randomized, placebo-controlled study. ( de Bri, E; Elvin, A; Lapidus, LJ; Lärfars, G; Levander, C; Ponzer, S; Rosfors, S, 2007)
"With patients in whom it is indicated, the home therapy ankle pathway has proved to be a safe and resource sparing method of managing ankle fractures prior to surgery."1.39Home therapy pathway - safe and streamlined method of initial management of ankle fractures. ( Baraza, N; Dhukaram, V; Lever, S, 2013)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Leone, S1
Zuccoli, ML1
Fucile, C1
Storace, S1
Martelli, A1
Mattioli, F1
Baraza, N1
Lever, S1
Dhukaram, V1
Goel, DP1
Buckley, R1
deVries, G1
Abelseth, G1
Ni, A1
Gray, R1
Lapidus, LJ2
Rosfors, S2
Ponzer, S2
Levander, C2
Elvin, A2
Lärfars, G2
de Bri, E2

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Different Approach to Preventing Thrombosis (ADAPT): A Randomized Controlled Trial Comparing Low Molecular Weight Heparin to Acetylsalicylic Acid in Orthopedic Trauma Patients[NCT02774265]Phase 3329 participants (Actual)Interventional2016-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Deep Venous Thromboembolism

DVT and how the diagnosis was made will be recorded. The number of events in participants in each arm will be compared to evaluate efficacy. (NCT02774265)
Timeframe: 90 days

InterventionParticipants (Count of Participants)
VTE Prophylaxis With Enoxaparin 30mg BID5
VTE Prophylaxis With Aspirin 81mg BID9

Number of Participants With Pulmonary Embolism Events

Bases on imaging obtained for symptoms. (NCT02774265)
Timeframe: 90 days

InterventionParticipants (Count of Participants)
VTE Prophylaxis With Enoxaparin 30mg BID6
VTE Prophylaxis With Aspirin 81mg BID2

Number of Participants With Treatment-related Bleeding Events as Assessed by the Need for Blood Transfusions and Procedures for Bleeding Complications After Initiation of the Study Medication.

Includes a greater than 2g/dL drop in hemoglobin, blood transfusion, hematoma evacuation, re-operation for a deep surgical site infection or minor procedure for bleeding and GI bleed (NCT02774265)
Timeframe: 90 days

InterventionParticipants (Count of Participants)
VTE Prophylaxis With Enoxaparin 30mg BID52
VTE Prophylaxis With Aspirin 81mg BID53

Reviews

1 review available for dalteparin and Ankle Injuries

ArticleYear
Heparin-induced acute adverse reaction--case report of a patient with acute trauma and a genetic predisposition to thrombotic events: a concurrence of events.
    Journal of clinical pharmacy and therapeutics, 2012, Volume: 37, Issue:6

    Topics: Ankle Injuries; Anticoagulants; Drug Hypersensitivity; Fractures, Bone; Genetic Predisposition to Di

2012

Trials

3 trials available for dalteparin and Ankle Injuries

ArticleYear
Prophylaxis of deep-vein thrombosis in fractures below the knee: a prospective randomised controlled trial.
    The Journal of bone and joint surgery. British volume, 2009, Volume: 91, Issue:3

    Topics: Adult; Aged; Ankle Injuries; Anticoagulants; Dalteparin; Double-Blind Method; Female; Fractures, Bon

2009
Prolonged thromboprophylaxis with dalteparin after surgical treatment of achilles tendon rupture: a randomized, placebo-controlled study.
    Journal of orthopaedic trauma, 2007, Volume: 21, Issue:1

    Topics: Achilles Tendon; Adolescent; Adult; Aged; Ankle Injuries; Anticoagulants; Dalteparin; Double-Blind M

2007
Prolonged thromboprophylaxis with Dalteparin during immobilization after ankle fracture surgery: a randomized placebo-controlled, double-blind study.
    Acta orthopaedica, 2007, Volume: 78, Issue:4

    Topics: Adolescent; Adult; Aged; Ankle Injuries; Anticoagulants; Casts, Surgical; Dalteparin; Double-Blind M

2007

Other Studies

1 other study available for dalteparin and Ankle Injuries

ArticleYear
Home therapy pathway - safe and streamlined method of initial management of ankle fractures.
    Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons, 2013, Volume: 19, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Ankle Injuries; Anticoagulants; Case-Control Studies; Casts, Surgica

2013