Page last updated: 2024-10-18

dalteparin and Ankle Fractures

dalteparin has been researched along with Ankle Fractures in 1 studies

Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)

Ankle Fractures: Fractures of any of the bones of the ANKLE.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Selby, R1
Geerts, WH1
Kreder, HJ1
Crowther, MA1
Kaus, L1
Sealey, F1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Clinically-Important Venous Thromboembolism Following Lower Extremity Fractures: Epidemiology & Prevention[NCT00187408]Phase 4700 participants Interventional2002-08-31Completed
A Different Approach to Preventing Thrombosis (ADAPT): A Randomized Controlled Trial Comparing Low Molecular Weight Heparin to Acetylsalicylic Acid in Orthopedic Trauma Patients[NCT02774265]Phase 3329 participants (Actual)Interventional2016-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Deep Venous Thromboembolism

DVT and how the diagnosis was made will be recorded. The number of events in participants in each arm will be compared to evaluate efficacy. (NCT02774265)
Timeframe: 90 days

InterventionParticipants (Count of Participants)
VTE Prophylaxis With Enoxaparin 30mg BID5
VTE Prophylaxis With Aspirin 81mg BID9

Number of Participants With Pulmonary Embolism Events

Bases on imaging obtained for symptoms. (NCT02774265)
Timeframe: 90 days

InterventionParticipants (Count of Participants)
VTE Prophylaxis With Enoxaparin 30mg BID6
VTE Prophylaxis With Aspirin 81mg BID2

Number of Participants With Treatment-related Bleeding Events as Assessed by the Need for Blood Transfusions and Procedures for Bleeding Complications After Initiation of the Study Medication.

Includes a greater than 2g/dL drop in hemoglobin, blood transfusion, hematoma evacuation, re-operation for a deep surgical site infection or minor procedure for bleeding and GI bleed (NCT02774265)
Timeframe: 90 days

InterventionParticipants (Count of Participants)
VTE Prophylaxis With Enoxaparin 30mg BID52
VTE Prophylaxis With Aspirin 81mg BID53

Trials

1 trial available for dalteparin and Ankle Fractures

ArticleYear
A double-blind, randomized controlled trial of the prevention of clinically important venous thromboembolism after isolated lower leg fractures.
    Journal of orthopaedic trauma, 2015, Volume: 29, Issue:5

    Topics: Adult; Aged; Ankle Fractures; Anticoagulants; Dalteparin; Double-Blind Method; Female; Fibula; Fract

2015
A double-blind, randomized controlled trial of the prevention of clinically important venous thromboembolism after isolated lower leg fractures.
    Journal of orthopaedic trauma, 2015, Volume: 29, Issue:5

    Topics: Adult; Aged; Ankle Fractures; Anticoagulants; Dalteparin; Double-Blind Method; Female; Fibula; Fract

2015
A double-blind, randomized controlled trial of the prevention of clinically important venous thromboembolism after isolated lower leg fractures.
    Journal of orthopaedic trauma, 2015, Volume: 29, Issue:5

    Topics: Adult; Aged; Ankle Fractures; Anticoagulants; Dalteparin; Double-Blind Method; Female; Fibula; Fract

2015
A double-blind, randomized controlled trial of the prevention of clinically important venous thromboembolism after isolated lower leg fractures.
    Journal of orthopaedic trauma, 2015, Volume: 29, Issue:5

    Topics: Adult; Aged; Ankle Fractures; Anticoagulants; Dalteparin; Double-Blind Method; Female; Fibula; Fract

2015