Page last updated: 2024-10-18

dalteparin and Adenocarcinoma

dalteparin has been researched along with Adenocarcinoma in 24 studies

Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)

Adenocarcinoma: A malignant epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
" In the study, the effect of dalteparin on pulmonary adenocarcinoma A549 cell line was observed in vitro."7.74The effect of dalteparin, a kind of low molecular weight heparin, on lung adenocarcinoma A549 cell line in vitro. ( Chen, X; Qu, X; Xiao, W; Zhou, S, 2008)
" In the study, the effect of dalteparin on pulmonary adenocarcinoma A549 cell line was observed in vitro."3.74The effect of dalteparin, a kind of low molecular weight heparin, on lung adenocarcinoma A549 cell line in vitro. ( Chen, X; Qu, X; Xiao, W; Zhou, S, 2008)
" The maximum tolerated dose (MTD) of lenalidomide given in combination with gemcitabine was defined as the highest dose level at which no more than one out of four (25%) subjects experiences a dose-limiting toxicity (DLT)."2.80A phase I dose-escalation study of lenalidomide in combination with gemcitabine in patients with advanced pancreatic cancer. ( Liljefors, M; Rossmann, E; Ullenhag, GJ, 2015)
"Patients with oesophageal cancer undergoing neoadjuvant chemoradiotherapy and surgery are at substantial risk of thromboembolic and bleeding events throughout all stages of treatment."1.56Thromboembolic and bleeding complications in patients with oesophageal cancer. ( Büller, HR; Hovenkamp, A; Hulshof, MCCM; Kamphuisen, PW; Middeldorp, S; Mulder, FI; van Berge Henegouwen, MI; van Es, N; van Laarhoven, HWM, 2020)
"HT29 human colorectal cancers were implanted in dorsal skinfold window chambers in athymic mice."1.42Microvascular effects of the low molecular weight heparins in a colorectal xenograft model: an intravital microscopy study. ( Ceelen, W; Debergh, I; Pattyn, P, 2015)
"The risk of prostate cancer-specific mortality (PCSM) was compared between the AC and non-AC groups."1.38Aspirin use and the risk of prostate cancer mortality in men treated with prostatectomy or radiotherapy. ( Carroll, PR; Chan, JM; Choe, KS; Cowan, JE; D'Amico, AV; Liauw, SL, 2012)
"The pattern of breast cancer metastasis may be determined by interactions between CXCR4 on breast cancer cells and CXCL12 within normal tissues."1.34Inhibition of CXCR4-mediated breast cancer metastasis: a potential role for heparinoids? ( Ali, S; Eldaly, H; Harvey, JR; Kirby, JA; Lennard, TW; Mellor, P, 2007)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (25.00)29.6817
2010's17 (70.83)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Mulder, FI1
Hovenkamp, A1
van Laarhoven, HWM1
Büller, HR1
Kamphuisen, PW1
Hulshof, MCCM1
van Berge Henegouwen, MI1
Middeldorp, S1
van Es, N1
Debergh, I1
Pattyn, P1
Ceelen, W1
Zhong, GX1
Gong, Y1
Yu, CJ1
Wu, SF1
Ma, QP1
Wang, Y1
Ren, J1
Zhang, XC1
Yang, WH1
Zhu, W1
Zhuang, X1
Qiao, T1
Xu, G1
Yuan, S1
Zhang, Q1
Chen, X2
Carmazzi, Y1
Iorio, M1
Armani, C1
Cianchetti, S1
Raggi, F1
Neri, T1
Cordazzo, C1
Petrini, S1
Vanacore, R1
Bogazzi, F1
Paggiaro, P1
Celi, A1
Hoe, V1
Kinnear, N1
Christidis, D1
O'Connell, H1
Martín Guerra, JM1
Asenjo, MM1
Dueñas Gutiérrez, CJ1
Gil González, I1
Pelzer, U1
Sinn, M1
Stieler, J1
Riess, H1
Papageorgiou, C1
Vandreden, P1
Marret, E1
Bonnet, F1
Robert, F1
Spyropoulos, A1
Galea, V1
Elalamy, I1
Hatmi, M1
Gerotziafas, GT1
Burtness, B1
Powell, M1
Catalano, P1
Berlin, J1
Liles, DK1
Chapman, AE1
Mitchell, E1
Benson, AB1
Kirienko, AI1
Andriiashkin, VV1
Lebedev, IS1
Bagirian, MS1
Babakova, NA1
Mitma, AA1
Varghese, JG1
Witt, D1
Zarich, SW1
Byrne, M2
Reynolds, JV1
O'Donnell, JS1
Keogan, M1
White, B1
Murphy, S1
Maher, SG1
Pidgeon, GP1
Abu Arab, W1
Kotb, R1
Sirois, M1
Rousseau, E1
Choe, KS1
Cowan, JE1
Chan, JM1
Carroll, PR1
D'Amico, AV1
Liauw, SL1
Pross, M2
Lippert, H2
Nestler, G2
Kuhn, R1
Langer, H2
Mantke, R1
Schulz, HU2
Zacharski, LR1
Misselwitz, F1
Krüger, S1
Halangk, W1
Ullenhag, GJ1
Rossmann, E1
Liljefors, M1
Xiao, W1
Qu, X1
Zhou, S1
Moore, A1
Lau, E1
Yang, C1
Mackool, B1
Kuter, DJ1
Matikas, A1
Vardakis, N1
Souglakos, J1
Georgoulias, V1
Auer, R1
Scheer, A1
Wells, PS1
Boushey, R1
Asmis, T1
Jonker, D1
Carrier, M1
Harvey, JR1
Mellor, P1
Eldaly, H1
Lennard, TW1
Kirby, JA1
Ali, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase I/II Study of Lenalidomide and Gemcitabine as First-line Treatment in Patients With Locally Advanced or Metastatic Pancreatic Cancer[NCT01547260]Phase 1/Phase 234 participants (Actual)Interventional2009-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for dalteparin and Adenocarcinoma

ArticleYear
Randomized Phase II Trial of Irinotecan/Docetaxel or Irinotecan/Docetaxel Plus Cetuximab for Metastatic Pancreatic Cancer: An Eastern Cooperative Oncology Group Study.
    American journal of clinical oncology, 2016, Volume: 39, Issue:4

    Topics: Adenocarcinoma; Aged; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; CA-19-9 Antige

2016
A phase I dose-escalation study of lenalidomide in combination with gemcitabine in patients with advanced pancreatic cancer.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Adenocarcinoma; Administration, Oral; Aged; Anticoagulants; Antineoplastic Combined Chemotherapy Pro

2015
The use of extended perioperative low molecular weight heparin (tinzaparin) to improve disease-free survival following surgical resection of colon cancer: a pilot randomized controlled trial.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2011, Volume: 22, Issue:8

    Topics: Adenocarcinoma; Aged; Canada; Colonic Neoplasms; Disease-Free Survival; Drug Administration Schedule

2011

Other Studies

21 other studies available for dalteparin and Adenocarcinoma

ArticleYear
Thromboembolic and bleeding complications in patients with oesophageal cancer.
    The British journal of surgery, 2020, Volume: 107, Issue:10

    Topics: Adenocarcinoma; Aged; Anticoagulants; Carcinoma, Squamous Cell; Chemoradiotherapy; Cohort Studies; E

2020
Microvascular effects of the low molecular weight heparins in a colorectal xenograft model: an intravital microscopy study.
    The Journal of surgical research, 2015, Volume: 194, Issue:2

    Topics: Adenocarcinoma; Animals; Anticoagulants; Colorectal Neoplasms; Enoxaparin; HT29 Cells; Humans; Immun

2015
Significantly inhibitory effects of low molecular weight heparin (Fraxiparine) on the motility of lung cancer cells and its related mechanism.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2015, Volume: 36, Issue:6

    Topics: Actin Cytoskeleton; Adenocarcinoma; Adenocarcinoma of Lung; Animals; Cell Adhesion; Cell Movement; C

2015
Combination of nadroparin with radiotherapy results in powerful synergistic antitumor effects in lung adenocarcinoma A549 cells.
    Oncology reports, 2016, Volume: 36, Issue:4

    Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Apoptosis; Basigin; Cell Movement; Cell Prolifer

2016
The mechanisms of nadroparin-mediated inhibition of proliferation of two human lung cancer cell lines.
    Cell proliferation, 2012, Volume: 45, Issue:6

    Topics: Adenocarcinoma; Anticoagulants; Apoptosis; Carcinoma, Squamous Cell; cdc25 Phosphatases; Cell Cycle

2012
Rectus sheath haematoma causing ureteric obstruction.
    BMJ case reports, 2018, Jul-10, Volume: 2018

    Topics: Adenocarcinoma; Aged, 80 and over; Anticoagulants; Colonic Neoplasms; Enoxaparin; Female; Gastrointe

2018
Synchronous Cardiopulmonary Consequences of the Hypercoagulable State Associated With Cancer.
    Archivos de bronconeumologia, 2019, Volume: 55, Issue:6

    Topics: Adenocarcinoma; Anticoagulants; Brain Ischemia; Computed Tomography Angiography; Endocarditis, Non-I

2019
[Primary pharmacological prevention of thromboembolic events in ambulatory patients with advanced pancreatic cancer treated with chemotherapy?].
    Deutsche medizinische Wochenschrift (1946), 2013, Volume: 138, Issue:41

    Topics: Adenocarcinoma; Ambulatory Care; Anticoagulants; Dalteparin; Dose-Response Relationship, Drug; Enoxa

2013
Lobectomy and postoperative thromboprophylaxis with enoxaparin improve blood hypercoagulability in patients with localized primary lung adenocarcinoma.
    Thrombosis research, 2013, Volume: 132, Issue:5

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Aged; Anticoagulants; Blood Coagulation; Blood Coagulation T

2013
[Thrombosis of inferior vena cava suprarenal portion and right atrium in case of stomach cancer].
    Khirurgiia, 2014, Issue:8

    Topics: Adenocarcinoma; Echocardiography, Three-Dimensional; Enoxaparin; Female; Fibrinolytic Agents; Gastre

2014
Stroke and a valvular lesion in a patient with stage IV non-small cell lung cancer.
    BMJ case reports, 2016, May-31, Volume: 2016

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Aged; Anticoagulants; Cerebellum; Diagnosis, Differential; E

2016
Long-term activation of the pro-coagulant response after neoadjuvant chemoradiation and major cancer surgery.
    British journal of cancer, 2010, Jan-05, Volume: 102, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Anticoagulants; Biomarkers; Carcinoma, Squamous Cell; Combined Modality

2010
Concentration- and time-dependent effects of enoxaparin on human adenocarcinomic epithelial cell line A549 proliferation in vitro.
    Canadian journal of physiology and pharmacology, 2011, Volume: 89, Issue:10

    Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Prolif

2011
Aspirin use and the risk of prostate cancer mortality in men treated with prostatectomy or radiotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Oct-01, Volume: 30, Issue:28

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Chemoprevention; Clopidogre

2012
Effect of low molecular weight heparin on intra-abdominal metastasis in a laparoscopic experimental study.
    International journal of colorectal disease, 2004, Volume: 19, Issue:2

    Topics: Abdominal Neoplasms; Adenocarcinoma; Animals; Anticoagulants; Disease Models, Animal; Dose-Response

2004
Heparin treatment of malignancy: the case for clinical trials in colon cancer.
    Thrombosis research, 2003, Jun-01, Volume: 110, Issue:4

    Topics: Adenocarcinoma; Animals; Anticoagulants; Clinical Trials as Topic; Colonic Neoplasms; Disease Models

2003
Low-molecular-weight heparin (reviparin) diminishes tumor cell adhesion and invasion in vitro, and decreases intraperitoneal growth of colonadeno-carcinoma cells in rats after laparoscopy.
    Thrombosis research, 2003, Jun-01, Volume: 110, Issue:4

    Topics: Abdominal Neoplasms; Adenocarcinoma; Animals; Anticoagulants; Cell Adhesion; Cell Line, Tumor; Hepar

2003
The effect of dalteparin, a kind of low molecular weight heparin, on lung adenocarcinoma A549 cell line in vitro.
    Cancer investigation, 2008, Volume: 26, Issue:7

    Topics: Adenocarcinoma; Anticoagulants; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell

2008
Dalteparin-induced skin necrosis in a patient with metastatic lung adenocarcinoma.
    American journal of clinical oncology, 2007, Volume: 30, Issue:3

    Topics: Adenocarcinoma; Anticoagulants; Dalteparin; Female; Humans; Liver Neoplasms; Lung Neoplasms; Middle

2007
A 52-year-old-male patient with metastatic non-small-cell lung cancer and recurrent venous thromboembolism in unusual sites despite anticoagulation.
    BMJ case reports, 2013, Sep-17, Volume: 2013

    Topics: Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Fatal Outcome; Fibrinolytic Agents; Heparin, Low-Mol

2013
Inhibition of CXCR4-mediated breast cancer metastasis: a potential role for heparinoids?
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Mar-01, Volume: 13, Issue:5

    Topics: Adenocarcinoma; Animals; Breast Neoplasms; Calcium; Cell Line, Tumor; Chemokine CXCL12; Chemokines,

2007