Page last updated: 2024-10-18

dalteparin and Acute Coronary Syndrome

dalteparin has been researched along with Acute Coronary Syndrome in 98 studies

Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)

Acute Coronary Syndrome: An episode of MYOCARDIAL ISCHEMIA that generally lasts longer than a transient anginal episode that ultimately may lead to MYOCARDIAL INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"This randomized prospective clinical trial aimed to evaluate safety and efficacy of preoperative use of eptifibatide in high risk patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS), requiring urgent coronary artery bypass graft surgery (CABG)."9.22Eptifibatide infusion versus placebo in high risk patients with non-ST segment elevation acute coronary syndromes managed with urgent coronary artery bypass graft surgery. A prospective multicenter randomized placebo-controlled clinical trial. ( Bochenek, A; Buldak, Ł; Buszman, P; Kondys, M; Milewski, K; Sanak, M; Wilczynski, M; Wita, K; Wybraniec, MT, 2016)
"Little is known about the efficacy of proton pump inhibitors compared with H(2) receptor antagonists in preventing adverse upper gastrointestinal complications in patients with acute coronary syndrome (ACS) or ST elevation myocardial infarction (STEMI) receiving aspirin, clopidogrel, and enoxaparin or thrombolytics."9.16Esomeprazole compared with famotidine in the prevention of upper gastrointestinal bleeding in patients with acute coronary syndrome or myocardial infarction. ( Chan, K; Chu, WM; Keung, KK; Kng, C; Kwan, A; Lam, KF; Lau, YK; Li, A; Ng, FH; Tunggal, P; Wong, BC, 2012)
"American College of Cardiology/American Heart Association/European Society of Cardiology (ACC/AHA/ESC) guidelines gave fondaparinux a class I recommendation for use in patients with non-ST elevation acute coronary syndromes (NSTE-ACS) undergoing invasive or conservative strategy."9.15Comparison of safety and efficacy between fondaparinux and nadroparin in non-ST elevation acute coronary syndromes. ( Chi, YP; Li, WZ; Liu, C; Liu, R; Song, L; Wang, SP; Yan, HB; Zhao, HJ; Zheng, B; Zhou, P, 2011)
"This study sought to evaluate the relative safety and efficacy of fondaparinux and enoxaparin in patients with acute coronary syndromes (ACS) treated with glycoprotein (GP) IIb/IIIa inhibitors or thienopyridines."9.14Efficacy and safety of fondaparinux versus enoxaparin in patients with acute coronary syndromes treated with glycoprotein IIb/IIIa inhibitors or thienopyridines: results from the OASIS 5 (Fifth Organization to Assess Strategies in Ischemic Syndromes) tria ( Afzal, R; Boden, WE; Budaj, A; Chrolavicius, S; Faxon, DP; Fox, KA; Granger, CB; Jolly, SS; Joyner, CD; Mehta, SR; Steg, PG; Valentin, V; Widimsky, P; Yusuf, S, 2009)
"The OASIS-5 (Organization to Assess Strategies in Ischemic Syndromes-5) trial demonstrated that fondaparinux was noninferior to enoxaparin while reducing the risk of bleeding by 50%."9.14Fondaparinux compared to enoxaparin in patients with acute coronary syndromes without ST-segment elevation: outcomes and treatment effect across different levels of risk. ( Afzal, R; Bassand, JP; Budaj, A; Chrolavicius, S; Flather, M; Fox, KA; Franzosi, MG; Granger, CB; Joyner, CD; Mehta, SR; Peters, RJ; Yusuf, S, 2009)
" We evaluated the immediate and early outcomes in patients with high-risk non-ST elevation acute coronary syndrome (NSTE ACS) who received tirofiban with conventional therapy compared to patients who received only conventional therapy (a combination of aspirin, clopidogrel, low-molecular-weight heparin with or without beta-blockers and angiotensin-converting enzyme inhibitors)."9.14Randomised controlled trial evaluating the role of tirofiban in high-risk non-ST elevation acute coronary syndromes: an East Indian perspective. ( Basak, S; Bhattacharya, R; Das Baksi, S; Dutta, D; Gangopadhyay, S; Pani, A; Sarkar, RN, 2010)
"Fondaparinux is a more cost-effective antithrombotic agent than enoxaparin in non-ST-elevation acute coronary syndrome."9.14Fondaparinux versus Enoxaparin in non-ST-elevation acute coronary syndromes: short-term cost and long-term cost-effectiveness using data from the Fifth Organization to Assess Strategies in Acute Ischemic Syndromes Investigators (OASIS-5) trial. ( Bakhai, A; Flather, M; Lozano-Ortega, G; Mehta, SR; Ormanidhi, O; Palmer, S; Sambrook, J; Sculpher, MJ; Steg, PG; Weintraub, W, 2009)
"The Fifth and Sixth Organization to Assess Strategies in Ischemic Syndromes (OASIS 5 and 6) trials evaluated fondaparinux, a synthetic factor Xa inhibitor, in patients with non-ST- and ST-segment elevation acute coronary syndromes, respectively."9.13Antithrombotic therapy with fondaparinux in relation to interventional management strategy in patients with ST- and non-ST-segment elevation acute coronary syndromes: an individual patient-level combined analysis of the Fifth and Sixth Organization to Ass ( Afzal, R; Avezum, A; Bassand, JP; Boden, WE; Budaj, A; Chrolavicius, S; Eikelboom, JW; Faxon, DP; Flather, M; Fox, KA; Granger, CB; Jolly, S; Mehta, SR; Piegas, LS; Rupprecht, HJ; Steg, PG; Widimsky, P; Yusuf, S, 2008)
"In the ACUITY trial, 13,819 patients with moderate- or high-risk acute coronary syndromes (ACS) were randomized to heparin (unfractionated or enoxaparin) plus glycoprotein IIb/IIIa inhibition (GPI), bivalirudin plus GPI, or bivalirudin monotherapy."9.13Safety and efficacy of bivalirudin monotherapy in patients with diabetes mellitus and acute coronary syndromes: a report from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial. ( Attubato, MJ; Ebrahimi, R; Feit, F; Manoukian, SV; Mehran, R; Ohman, EM; Pollack, CV; Stone, GW, 2008)
"This study was designed to determine the impact of bivalirudin on 1-year outcomes in acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI)."9.13Safety and efficacy of bivalirudin with and without glycoprotein IIb/IIIa inhibitors in patients with acute coronary syndromes undergoing percutaneous coronary intervention 1-year results from the ACUITY (Acute Catheterization and Urgent Intervention Tria ( Bertrand, ME; Colombo, A; Cox, DA; Lansky, AJ; Lincoff, AM; Manoukian, SV; McLaurin, BT; Mehran, R; Moses, JW; Ohman, EM; Pocock, SJ; Stone, GW; Ware, JA; White, HD, 2008)
"Enoxaparin and Fondaparinux are potential anticoagulants which are used peri-operatively in the management of patients with Acute Coronary Syndrome (ACS)."8.95Choosing between Enoxaparin and Fondaparinux for the management of patients with acute coronary syndrome: A systematic review and meta-analysis. ( Bundhun, PK; Shaik, M; Yuan, J, 2017)
"Fondaparinux is thought to have the most favorable risk-benefit profile among all anticoagulants in non-ST-elevation acute coronary syndrome (NSTE-ACS)."8.02Fondaparinux versus enoxaparin in the contemporary management of non-ST-elevation acute coronary syndromes. Insights from a multicenter registry. ( Almendro-Delia, M; Arboleda Sánchez, JA; Blanco-Ponce, E; Carmona-Carmona, J; Castillo Caballero, JA; Fernández García, I; García-Del Río, M; García-Rubira, JC; Hidalgo-Urbano, RJ; Izquierdo-Bajo, Á; Madrona-Jiménez, L; Rodríguez Yáñez, JC; Seoane-García, T; Soto Blanco, JM, 2021)
"There are limited data on bivalirudin monotherapy in patients with non-ST-segment elevation acute coronary syndromes (NSTE-ACS) with positive biomarkers of myocardial necrosis (troponin and/or creatine kinase-myocardial band isoenzyme)."7.96Safety and efficacy of bivalirudin monotherapy in patients with non-ST-segment elevation acute coronary syndromes with positive biomarkers undergoing percutaneous coronary intervention: a report from the Acute Catheterization and Urgent Intervention Triag ( Bansilal, S; Ben-Yehuda, O; Brener, SJ; Chen, S; Dangas, GD; Feite, F; Huang, X; Kirtane, AJ; Mehran, R; Redfors, B; Souza, CF; Stone, GW; Zhang, Y, 2020)
"Recent studies have shown fondaparinux's superiority over enoxaparin in patients with non-ST elevation acute coronary syndrome (ACS), especially in relation to bleeding reduction."7.83Fondaparinux versus Enoxaparin - Which is the Best Anticoagulant for Acute Coronary Syndrome? - Brazilian Registry Data. ( Bossa, AS; César, MC; Leal, TC; Okada, MY; Oliveira, MT; Pedroti, FC; Roque, EA; Silva, PG; Simões, SA; Soeiro, AM, 2016)
"Between 2006 and 2007, the use of fondaparinux in patients with acute coronary syndromes increased considerably, either because it was used instead of enoxaparin or because of a switch from UFH."7.76Routine use of fondaparinux in acute coronary syndromes: a 2-year multicenter experience. ( Bassand, JP; Chopard, R; Descotes-Genon, V; Dutheil, J; Ecarnot, F; Meneveau, N; Schiele, F; Seronde, MF, 2010)
"The combination of aspirin, clopidogrel, and enoxaparin (combination therapy) is the standard treatment for acute coronary syndrome but is associated with gastrointestinal bleeding."7.74Gastrointestinal bleeding in patients receiving a combination of aspirin, clopidogrel, and enoxaparin in acute coronary syndrome. ( Chang, CM; Chu, WM; Lam, KF; Lau, YK; Ng, FH; Wong, BC; Wong, SY, 2008)
"The primary safety end point was bleeding events, as defined by the International Society on Thrombosis and Haemostasis, and the primary efficacy end point was major adverse cardiovascular events (MACEs), including cardiac death, myocardial infarction, rerevascularization, or stroke during the 6-month follow-up."7.30Effect of Rivaroxaban vs Enoxaparin on Major Cardiac Adverse Events and Bleeding Risk in the Acute Phase of Acute Coronary Syndrome: The H-REPLACE Randomized Equivalence and Noninferiority Trial. ( Chen, F; Fu, G; Ge, L; Huang, L; Jiang, W; Liu, C; Liu, Q; Ouyang, Z; Pan, G; Pan, H; Shen, Q; Xiao, Y; Zeng, G; Zhang, Y; Zheng, Z; Zhou, C; Zhou, S; Zhu, C, 2023)
" The primary efficacy endpoint is a composite of major adverse cardiac events (MACE), including cardiac death, myocardial infarction, re-revascularization or stroke, and major bleeding events."7.11Rationale and Design of the H-REPLACE Study: Safety and Efficacy of LMWH Versus Rivaroxaban in ChinEse Patients HospitaLized with Acute Coronary SyndromE. ( Fang, Z; Hu, X; Liu, Q; Tang, L; Xiao, Y; Zhou, S, 2022)
"Fondaparinux was compared with enoxaparin or usual care, depending on the setting."6.44Efficacy and safety of fondaparinux in patients with acute coronary syndromes. ( Bassand, JP; Cadroy, Y; Richard-Lordereau, I, 2007)
"Fondaparinux was introduced and evaluated in a number of large randomised, controlled trials."5.42Cost-Effectiveness Analysis of Fondaparinux vs Enoxaparin in Non-ST Elevation Acute Coronary Syndrome in Thailand. ( Chaiyakunapruk, N; Nathisuwan, S; Permsuwan, U; Sukonthasarn, A, 2015)
"Fondaparinux has demonstrated equivalence to enoxaparin in reducing cardiovascular events, but with a lower rate of bleeding in patients using fondaparinux."5.38Cost-effectiveness of fondaparinux in patients with acute coronary syndrome without ST-segment elevation. ( Machado, M; Olimpio, A; Pepe, C; Ramos, R, 2012)
"Fondaparinux was shown to be efficacious in the prevention of deep vein thrombosis vs low-molecular-weight heparins, while in the setting of venous thrombo-embolic disease, it was shown to be noninferior to enoxaparin and UFH."5.36Fondaparinux and acute coronary syndromes: update on the OASIS 5-6 studies. ( Schiele, F, 2010)
"In patients with NSTE-ACS undergoing an early invasive strategy, treatment with bivalirudin alone significantly reduced major bleeding and improved net clinical outcomes during the upstream medical management phase with comparable rates of MACE."5.22Impact of anticoagulation regimen prior to revascularization in patients with non-ST-segment elevation acute coronary syndromes: The ACUITY trial. ( Bernstein, D; Bertrand, ME; Cequier, AR; Deliargyris, EN; Desmet, W; Droppa, M; Gawaz, M; Geisler, T; Hoekstra, JW; Lincoff, AM; Mehran, R; Rasmussen, LH; Steinhubl, SR; Stone, GW, 2016)
"This randomized prospective clinical trial aimed to evaluate safety and efficacy of preoperative use of eptifibatide in high risk patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS), requiring urgent coronary artery bypass graft surgery (CABG)."5.22Eptifibatide infusion versus placebo in high risk patients with non-ST segment elevation acute coronary syndromes managed with urgent coronary artery bypass graft surgery. A prospective multicenter randomized placebo-controlled clinical trial. ( Bochenek, A; Buldak, Ł; Buszman, P; Kondys, M; Milewski, K; Sanak, M; Wilczynski, M; Wita, K; Wybraniec, MT, 2016)
"Little is known about the efficacy of proton pump inhibitors compared with H(2) receptor antagonists in preventing adverse upper gastrointestinal complications in patients with acute coronary syndrome (ACS) or ST elevation myocardial infarction (STEMI) receiving aspirin, clopidogrel, and enoxaparin or thrombolytics."5.16Esomeprazole compared with famotidine in the prevention of upper gastrointestinal bleeding in patients with acute coronary syndrome or myocardial infarction. ( Chan, K; Chu, WM; Keung, KK; Kng, C; Kwan, A; Lam, KF; Lau, YK; Li, A; Ng, FH; Tunggal, P; Wong, BC, 2012)
"American College of Cardiology/American Heart Association/European Society of Cardiology (ACC/AHA/ESC) guidelines gave fondaparinux a class I recommendation for use in patients with non-ST elevation acute coronary syndromes (NSTE-ACS) undergoing invasive or conservative strategy."5.15Comparison of safety and efficacy between fondaparinux and nadroparin in non-ST elevation acute coronary syndromes. ( Chi, YP; Li, WZ; Liu, C; Liu, R; Song, L; Wang, SP; Yan, HB; Zhao, HJ; Zheng, B; Zhou, P, 2011)
"The objective was to assess the safety and efficacy of bivalirudin monotherapy in patients with high-risk acute coronary syndrome (ACS) presenting to the emergency department (ED)."5.14Safety and efficacy of bivalirudin in high-risk patients admitted through the emergency department. ( Blomkalns, AL; Brogan, GX; Diercks, DB; Gersh, BJ; Hoekstra, JW; Hollander, JE; Manoukian, SV; Miller, CD; Peacock, WF; Pollack, CV; Stone, GW, 2009)
"In the OASIS-5 trial, fondaparinux reduced major bleeding with similar short-term efficacy as enoxaparin but lowered death and stroke during long-term follow-up."5.14Comparison of the anticoagulant intensities of fondaparinux and enoxaparin in the Organization to Assess Strategies in Acute Ischemic Syndromes (OASIS)-5 trial. ( Afzal, R; Anderson, JA; Budaj, A; Eikelboom, JW; Fox, KA; Hirsh, J; Johnston, M; Mehta, SR; Yusuf, S, 2010)
" We evaluated the immediate and early outcomes in patients with high-risk non-ST elevation acute coronary syndrome (NSTE ACS) who received tirofiban with conventional therapy compared to patients who received only conventional therapy (a combination of aspirin, clopidogrel, low-molecular-weight heparin with or without beta-blockers and angiotensin-converting enzyme inhibitors)."5.14Randomised controlled trial evaluating the role of tirofiban in high-risk non-ST elevation acute coronary syndromes: an East Indian perspective. ( Basak, S; Bhattacharya, R; Das Baksi, S; Dutta, D; Gangopadhyay, S; Pani, A; Sarkar, RN, 2010)
" We examined the incidence and outcomes after bleeding in 20 078 patients with acute coronary syndromes (ACS) enrolled in the OASIS-5 trial who were treated with fondaparinux or the low-molecular weight heparin, enoxaparin."5.14Improving clinical outcomes by reducing bleeding in patients with non-ST-elevation acute coronary syndromes. ( Afzal, R; Bassand, JP; Budaj, A; Chrolavicius, S; Eikelboom, JW; Fox, KA; Granger, CB; Joyner, CD; Mehta, SR; Peters, RJ; Wallentin, L; Yusuf, S, 2009)
"The OASIS-5 (Organization to Assess Strategies in Ischemic Syndromes-5) trial demonstrated that fondaparinux was noninferior to enoxaparin while reducing the risk of bleeding by 50%."5.14Fondaparinux compared to enoxaparin in patients with acute coronary syndromes without ST-segment elevation: outcomes and treatment effect across different levels of risk. ( Afzal, R; Bassand, JP; Budaj, A; Chrolavicius, S; Flather, M; Fox, KA; Franzosi, MG; Granger, CB; Joyner, CD; Mehta, SR; Peters, RJ; Yusuf, S, 2009)
" Patients age > or =75 years treated with bivalirudin alone had similar ischemic outcomes, but significantly lower rates of bleeding compared with those treated with heparin and glycoprotein IIb/IIIa inhibitors overall and in the PCI subset."5.14Advanced age, antithrombotic strategy, and bleeding in non-ST-segment elevation acute coronary syndromes: results from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial. ( Alexander, KP; Bertrand, ME; Feit, F; Gersh, BJ; Hoekstra, J; Lopes, RD; Manoukian, SV; Ohman, EM; Pollack, CV; Stone, GW; White, HD, 2009)
"Fondaparinux is a more cost-effective antithrombotic agent than enoxaparin in non-ST-elevation acute coronary syndrome."5.14Fondaparinux versus Enoxaparin in non-ST-elevation acute coronary syndromes: short-term cost and long-term cost-effectiveness using data from the Fifth Organization to Assess Strategies in Acute Ischemic Syndromes Investigators (OASIS-5) trial. ( Bakhai, A; Flather, M; Lozano-Ortega, G; Mehta, SR; Ormanidhi, O; Palmer, S; Sambrook, J; Sculpher, MJ; Steg, PG; Weintraub, W, 2009)
"The study is a prospective single centre open-label trial of patients with high-risk acute coronary syndrome treated with percutaneous intervention (PCI) who were randomized to anticoagulation with UFH or enoxaparin with HD-tirofiban (25 microg kg(-1) bolus)."5.14High-dose tirofiban with enoxaparin and inflammatory markers in high-risk percutaneous intervention. ( Aroney, CN; Bett, JH; Perrin, EJ; Ray, MJ; Walters, DL; Wood, P, 2010)
"This study sought to evaluate the relative safety and efficacy of fondaparinux and enoxaparin in patients with acute coronary syndromes (ACS) treated with glycoprotein (GP) IIb/IIIa inhibitors or thienopyridines."5.14Efficacy and safety of fondaparinux versus enoxaparin in patients with acute coronary syndromes treated with glycoprotein IIb/IIIa inhibitors or thienopyridines: results from the OASIS 5 (Fifth Organization to Assess Strategies in Ischemic Syndromes) tria ( Afzal, R; Boden, WE; Budaj, A; Chrolavicius, S; Faxon, DP; Fox, KA; Granger, CB; Jolly, SS; Joyner, CD; Mehta, SR; Steg, PG; Valentin, V; Widimsky, P; Yusuf, S, 2009)
"The Fifth and Sixth Organization to Assess Strategies in Ischemic Syndromes (OASIS 5 and 6) trials evaluated fondaparinux, a synthetic factor Xa inhibitor, in patients with non-ST- and ST-segment elevation acute coronary syndromes, respectively."5.13Antithrombotic therapy with fondaparinux in relation to interventional management strategy in patients with ST- and non-ST-segment elevation acute coronary syndromes: an individual patient-level combined analysis of the Fifth and Sixth Organization to Ass ( Afzal, R; Avezum, A; Bassand, JP; Boden, WE; Budaj, A; Chrolavicius, S; Eikelboom, JW; Faxon, DP; Flather, M; Fox, KA; Granger, CB; Jolly, S; Mehta, SR; Piegas, LS; Rupprecht, HJ; Steg, PG; Widimsky, P; Yusuf, S, 2008)
"This study was designed to determine the impact of bivalirudin on 1-year outcomes in acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI)."5.13Safety and efficacy of bivalirudin with and without glycoprotein IIb/IIIa inhibitors in patients with acute coronary syndromes undergoing percutaneous coronary intervention 1-year results from the ACUITY (Acute Catheterization and Urgent Intervention Tria ( Bertrand, ME; Colombo, A; Cox, DA; Lansky, AJ; Lincoff, AM; Manoukian, SV; McLaurin, BT; Mehran, R; Moses, JW; Ohman, EM; Pocock, SJ; Stone, GW; Ware, JA; White, HD, 2008)
"In the ACUITY trial, 13,819 patients with moderate- or high-risk acute coronary syndromes (ACS) were randomized to heparin (unfractionated or enoxaparin) plus glycoprotein IIb/IIIa inhibition (GPI), bivalirudin plus GPI, or bivalirudin monotherapy."5.13Safety and efficacy of bivalirudin monotherapy in patients with diabetes mellitus and acute coronary syndromes: a report from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial. ( Attubato, MJ; Ebrahimi, R; Feit, F; Manoukian, SV; Mehran, R; Ohman, EM; Pollack, CV; Stone, GW, 2008)
"Enoxaparin and Fondaparinux are potential anticoagulants which are used peri-operatively in the management of patients with Acute Coronary Syndrome (ACS)."4.95Choosing between Enoxaparin and Fondaparinux for the management of patients with acute coronary syndrome: A systematic review and meta-analysis. ( Bundhun, PK; Shaik, M; Yuan, J, 2017)
"These analyses suggest a more protective effect of well-controlled warfarin, but not enoxaparin, compared with dabigatran in preventing myocardial infarction in multiple clinical settings."4.89Cardiovascular outcomes during treatment with dabigatran: comprehensive analysis of individual subject data by treatment. ( Clemens, A; Fraessdorf, M; Friedman, J, 2013)
" Newer agents, such as bivalirudin or fondaparinux, reduce bleeding complications, with no improvement in anti-ischemic efficacy."4.86Pharmacologic therapy for non ST-segment elevation acute coronary syndromes: focus on antithrombotic therapy. ( Aïssaoui, N; Danchin, N, 2010)
" We explore the role of glycoprotein IIb-IIIa inhibitors and the direct thrombin inhibitor bivalirudin in ACS patients, and consider the difficulties involved in reducing ischemic events while limiting bleeding risks."4.84Current update on glycoprotein IIb-IIIa and direct thrombin inhibition in percutaneous coronary intervention for non-ST elevation acute coronary syndromes: balancing bleeding risk and antiplatelet efficacy. ( Kwa, AT; Rogers, JH, 2008)
"Fondaparinux is thought to have the most favorable risk-benefit profile among all anticoagulants in non-ST-elevation acute coronary syndrome (NSTE-ACS)."4.02Fondaparinux versus enoxaparin in the contemporary management of non-ST-elevation acute coronary syndromes. Insights from a multicenter registry. ( Almendro-Delia, M; Arboleda Sánchez, JA; Blanco-Ponce, E; Carmona-Carmona, J; Castillo Caballero, JA; Fernández García, I; García-Del Río, M; García-Rubira, JC; Hidalgo-Urbano, RJ; Izquierdo-Bajo, Á; Madrona-Jiménez, L; Rodríguez Yáñez, JC; Seoane-García, T; Soto Blanco, JM, 2021)
"There are limited data on bivalirudin monotherapy in patients with non-ST-segment elevation acute coronary syndromes (NSTE-ACS) with positive biomarkers of myocardial necrosis (troponin and/or creatine kinase-myocardial band isoenzyme)."3.96Safety and efficacy of bivalirudin monotherapy in patients with non-ST-segment elevation acute coronary syndromes with positive biomarkers undergoing percutaneous coronary intervention: a report from the Acute Catheterization and Urgent Intervention Triag ( Bansilal, S; Ben-Yehuda, O; Brener, SJ; Chen, S; Dangas, GD; Feite, F; Huang, X; Kirtane, AJ; Mehran, R; Redfors, B; Souza, CF; Stone, GW; Zhang, Y, 2020)
"Recent studies have shown fondaparinux's superiority over enoxaparin in patients with non-ST elevation acute coronary syndrome (ACS), especially in relation to bleeding reduction."3.83Fondaparinux versus Enoxaparin - Which is the Best Anticoagulant for Acute Coronary Syndrome? - Brazilian Registry Data. ( Bossa, AS; César, MC; Leal, TC; Okada, MY; Oliveira, MT; Pedroti, FC; Roque, EA; Silva, PG; Simões, SA; Soeiro, AM, 2016)
"Between 2006 and 2007, the use of fondaparinux in patients with acute coronary syndromes increased considerably, either because it was used instead of enoxaparin or because of a switch from UFH."3.76Routine use of fondaparinux in acute coronary syndromes: a 2-year multicenter experience. ( Bassand, JP; Chopard, R; Descotes-Genon, V; Dutheil, J; Ecarnot, F; Meneveau, N; Schiele, F; Seronde, MF, 2010)
"The combination of aspirin, clopidogrel, and enoxaparin (combination therapy) is the standard treatment for acute coronary syndrome but is associated with gastrointestinal bleeding."3.74Gastrointestinal bleeding in patients receiving a combination of aspirin, clopidogrel, and enoxaparin in acute coronary syndrome. ( Chang, CM; Chu, WM; Lam, KF; Lau, YK; Ng, FH; Wong, BC; Wong, SY, 2008)
"The primary safety end point was bleeding events, as defined by the International Society on Thrombosis and Haemostasis, and the primary efficacy end point was major adverse cardiovascular events (MACEs), including cardiac death, myocardial infarction, rerevascularization, or stroke during the 6-month follow-up."3.30Effect of Rivaroxaban vs Enoxaparin on Major Cardiac Adverse Events and Bleeding Risk in the Acute Phase of Acute Coronary Syndrome: The H-REPLACE Randomized Equivalence and Noninferiority Trial. ( Chen, F; Fu, G; Ge, L; Huang, L; Jiang, W; Liu, C; Liu, Q; Ouyang, Z; Pan, G; Pan, H; Shen, Q; Xiao, Y; Zeng, G; Zhang, Y; Zheng, Z; Zhou, C; Zhou, S; Zhu, C, 2023)
" The primary efficacy endpoint is a composite of major adverse cardiac events (MACE), including cardiac death, myocardial infarction, re-revascularization or stroke, and major bleeding events."3.11Rationale and Design of the H-REPLACE Study: Safety and Efficacy of LMWH Versus Rivaroxaban in ChinEse Patients HospitaLized with Acute Coronary SyndromE. ( Fang, Z; Hu, X; Liu, Q; Tang, L; Xiao, Y; Zhou, S, 2022)
" Strategies to ensure adherence to dosing guidelines of enoxaparin during PCI should be considered."2.75Enoxaparin 0.3 mg/kg IV supplement for patients transitioning to PCI after subcutaneous enoxaparin therapy for NSTE ACS: a subgroup analysis from the SYNERGY trial. ( Antman, EM; Aylward, PE; Califf, RM; Cohen, M; Kleiman, NS; Lan, L; Levine, GN; Mahaffey, KW; Pieper, KS; White, HD, 2010)
"We evaluated the early pharmacodynamic profile of the combined 30 mg intravenous and 1 mg/kg subcutaneous enoxaparin loading utilized in the TIMI 11B and ExTRACT TIMI 25 trials."2.74The pharmacodynamics of enoxaparin in percutaneous coronary intervention with precise rapid enoxaparin loading (PEPCI-PRE study). ( Atherley, TH; Fry, ET; Martin, JL; Martin, SS; Martin, T; Slepian, MJ, 2009)
"The administration of stack-on UFH to subjects already receiving recommended enoxaparin dosing may result in over-anticoagulation, and should be avoided."2.74Adding intravenous unfractionated heparin to standard enoxaparin causes excessive anticoagulation not detected by activated clotting time: results of the STACK-on to ENOXaparin (STACKENOX) study. ( Bal dit Sollier, C; Drouet, L; Martin, J, 2009)
"Bleeding is associated with adverse outcome in acute coronary syndromes."2.73Bleeding and outcome in acute coronary syndrome: insights from continuous electrocardiogram monitoring in the Integrilin and Enoxaparin Randomized Assessment of Acute Coronary Syndrome Treatment (INTERACT) Trial. ( DeYoung, P; Fitchett, DH; Goodman, SG; Huynh, T; Langer, A; Weeks, A; Yan, AT; Yan, RT, 2008)
"Thrombocytopenia was defined as a platelet count <100 x 10(9)/L or a >50% decrease from baseline."2.73Effect of thrombocytopenia on outcomes following treatment with either enoxaparin or unfractionated heparin in patients presenting with acute coronary syndromes. ( Antman, EM; Bradner, JE; Gibson, CM; Giugliano, RP; Jang, IK; Morrow, DA; Qin, J; Scirica, B; Shui, A; Wiviott, SD; Yeh, RW, 2007)
" Dosing schedules based on pharmacodynamic and clinical data offer a seamless transition for enoxaparin from the medical management phase to PCI."2.47Use of low-molecular-weight heparins during percutaneous coronary intervention. ( Martin, JL; Slepian, M, 2011)
"Fondaparinux was compared with enoxaparin or usual care, depending on the setting."2.44Efficacy and safety of fondaparinux in patients with acute coronary syndromes. ( Bassand, JP; Cadroy, Y; Richard-Lordereau, I, 2007)
"Fondaparinux has been shown to be as effective as enoxaparin in the prevention of thrombosis in patients undergoing orthopedic surgery and showed similar results compared to enoxaparin or UFH in patients with deep-vein-thrombosis or pulmonary embolism."2.44Factor Xa inactivation in acute coronary syndrome. ( Barantke, M; Bonnemeier, H, 2008)
"Fondaparinux was introduced and evaluated in a number of large randomised, controlled trials."1.42Cost-Effectiveness Analysis of Fondaparinux vs Enoxaparin in Non-ST Elevation Acute Coronary Syndrome in Thailand. ( Chaiyakunapruk, N; Nathisuwan, S; Permsuwan, U; Sukonthasarn, A, 2015)
" In conclusion, compared with immediate PCI, d-PCI after ATT in selected, stabilized patients with ACS and a large intracoronary thrombus and without an urgent need for revascularization is probably safe and associated with a reduction in thrombotic burden, angiographic complications, and the need of revascularization."1.39Safety and efficacy of intense antithrombotic treatment and percutaneous coronary intervention deferral in patients with large intracoronary thrombus. ( Alfonso, F; Bañuelos, C; Echavarría-Pinto, M; Escaned, J; Fernández, C; Fernandez-Ortiz, A; García, E; Gonzalo, N; Gorgadze, T; Hernández, R; Ibañez, B; Jiménez-Quevedo, P; Lopes, R; Macaya, C; Nuñez-Gil, IJ, 2013)
"Fondaparinux has demonstrated equivalence to enoxaparin in reducing cardiovascular events, but with a lower rate of bleeding in patients using fondaparinux."1.38Cost-effectiveness of fondaparinux in patients with acute coronary syndrome without ST-segment elevation. ( Machado, M; Olimpio, A; Pepe, C; Ramos, R, 2012)
"We report a case of bilateral pulmonary embolism in a patient of 50 years."1.37[Pulmonary embolism mimicking acute anterior myocardial infarction: diagnostic trap]. ( Bodian, M; Diack, B; Diao, M; Hakim, R; Kagambèga, LJ; Kane, A; Kane, M; Mbaye, A; Ndiaye, MB; Pessinaba, S; Sow, DD; Yaméogo, NV, 2011)
" Enoxaparin was dosed as 1 mg/kg regardless of body weight without maximum."1.36Obesity in patients with non-ST-segment elevation acute coronary syndromes: results from the SYNERGY trial. ( Antman, EM; Aylward, PE; Becker, RC; Califf, RM; Col, JJ; Ducas, J; Ferguson, JJ; Gallo, R; Goodman, SG; Langer, A; Levine, GN; Mahaffey, KW; Spinler, SA; Tonev, ST; White, HD, 2010)
"Fondaparinux was shown to be efficacious in the prevention of deep vein thrombosis vs low-molecular-weight heparins, while in the setting of venous thrombo-embolic disease, it was shown to be noninferior to enoxaparin and UFH."1.36Fondaparinux and acute coronary syndromes: update on the OASIS 5-6 studies. ( Schiele, F, 2010)
"Fondaparinux is a synthetic pentasaccharide belonging to a new group of anticoagulants that inhibit thrombin formation by inhibiting Factor Xa, which is located at the crossing of both the intrinsic and extrinsic pathways."1.35Fondaparinux: an overview. ( Banerjee, P; Goyal, D; Lip, GY; Nadar, SK; Shantsila, E, 2009)
"To evaluate how enoxaparin is dosed in contemporary clinical practice as a function of patients' total body weight (TBW) and body mass index (BMI), and to determine any association between dose and major bleeding."1.35Weight-based dosing of enoxaparin in obese patients with non-ST-segment elevation acute coronary syndromes: results from the CRUSADE initiative. ( Alexander, KP; Gibler, WB; Ohman, EM; Ou, FS; Peterson, ED; Pollack, CV; Roe, MT; Spinler, SA, 2009)
"Important CKD disagreements occur in approximately 20% of acute coronary syndrome patients, affecting dosing adjustments in those already susceptible to bleeding."1.35Cockcroft-Gault versus modification of diet in renal disease: importance of glomerular filtration rate formula for classification of chronic kidney disease in patients with non-ST-segment elevation acute coronary syndromes. ( Alexander, KP; Chen, AY; Gibler, WB; Harrington, RA; Melloni, C; Newby, LK; Ohman, EM; Peterson, ED; Roe, MT; Spinler, SA; Szczech, LA, 2008)
" One major adverse clinical event (0."1.34Effectiveness and safety of reduced-dose enoxaparin in non-ST-segment elevation acute coronary syndrome followed by antiplatelet therapy alone for percutaneous coronary intervention. ( Davis, KE; Denardo, SJ; Tcheng, JE, 2007)

Research

Studies (98)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's49 (50.00)29.6817
2010's42 (42.86)24.3611
2020's7 (7.14)2.80

Authors

AuthorsStudies
Sun, CY1
Xia, HY1
Li, XQ1
Jin, LJ1
Lu, CL1
Ni, RY1
Yang, JG1
Hu, DY1
Guo, JX1
Yan, HB1
Song, L1
Liu, R1
Zhao, HJ1
Wang, SP1
Chi, YP1
Zheng, B1
Li, WZ1
Liu, C2
Zhou, P1
Latacz, P1
Rostoff, P1
Wyderka, R1
Rudnik, A1
Kondys, M2
Marut, A1
Buszman, P2
Piwowarska, W1
Camporese, G1
Bernardi, E1
Noventa, F1
Zhou, S2
Xiao, Y2
Zhou, C1
Zheng, Z1
Jiang, W1
Shen, Q1
Zhu, C1
Pan, H1
Zeng, G1
Ge, L1
Zhang, Y2
Ouyang, Z1
Fu, G1
Pan, G1
Chen, F1
Huang, L1
Liu, Q2
Weerasaksanti, A1
Siwamogsatham, S1
Kunlamas, Y1
Bunditanukul, K1
Huang, X1
Chen, S1
Redfors, B1
Souza, CF1
Mehran, R8
Bansilal, S1
Kirtane, AJ1
Brener, SJ2
Feite, F1
Dangas, GD1
Ben-Yehuda, O1
Stone, GW9
Rosenthal, N1
Xiao, Z1
Kartashov, A1
Levorsen, A1
Shah, BR1
Meenpidiyil, SS1
Azeez, S1
Kumar, VP1
Suresh, D1
Kalathathoduuill, S1
Thandupara, S1
Puthukudi, MH1
Tang, L1
Hu, X1
Fang, Z1
Almendro-Delia, M1
Izquierdo-Bajo, Á1
Madrona-Jiménez, L1
Blanco-Ponce, E1
Seoane-García, T1
García-Del Río, M1
Carmona-Carmona, J1
Arboleda Sánchez, JA1
Rodríguez Yáñez, JC1
Soto Blanco, JM1
Fernández García, I1
Castillo Caballero, JA1
Hidalgo-Urbano, RJ1
García-Rubira, JC1
Bundhun, PK1
Shaik, M1
Yuan, J1
Echavarría-Pinto, M1
Lopes, R1
Gorgadze, T1
Gonzalo, N1
Hernández, R1
Jiménez-Quevedo, P1
Alfonso, F1
Bañuelos, C1
Nuñez-Gil, IJ1
Ibañez, B1
Fernández, C1
Fernandez-Ortiz, A1
García, E1
Macaya, C1
Escaned, J1
Vavalle, JP1
Clare, R1
Chiswell, K1
Rao, SV2
Petersen, JL2
Kleiman, NS6
Mahaffey, KW14
Wang, TY1
Clemens, A1
Fraessdorf, M1
Friedman, J1
Singh, D1
Gupta, K1
Vacek, JL1
Jinatongthai, P1
Khaisombut, N1
Likittanasombat, K1
Chaiyakunapruk, N2
Watcharathanakij, S1
Nathisuwan, S2
Huber, K2
Bates, ER1
Valgimigli, M2
Wallentin, L4
Kristensen, SD1
Anderson, JL1
Lopez Sendon, JL1
Tubaro, M1
Granger, CB6
Bode, C1
Ohman, EM8
Steg, PG4
Permsuwan, U1
Sukonthasarn, A1
Geisler, T1
Droppa, M1
Gawaz, M1
Steinhubl, SR2
Bertrand, ME5
Lincoff, AM3
Cequier, AR1
Desmet, W2
Rasmussen, LH2
Hoekstra, JW4
Bernstein, D1
Deliargyris, EN1
Mayer, M2
Ross Terres, JA1
Lozano-Ortega, G2
Kendall, R1
Sculpher, MJ2
Wilczynski, M1
Wybraniec, MT1
Milewski, K1
Sanak, M1
Wita, K1
Buldak, Ł1
Bochenek, A1
Soeiro, AM1
Silva, PG1
Roque, EA1
Bossa, AS1
César, MC1
Simões, SA1
Okada, MY1
Leal, TC1
Pedroti, FC1
Oliveira, MT1
Lopes, RD2
Alexander, KP5
Marcucci, G1
White, HD12
Spinler, S1
Col, J1
Aylward, PE7
Califf, RM10
Leung, S1
Gallup, D1
Cohen, M7
Antman, EM8
Goodman, SG7
Harrington, RA3
Langer, A5
Aylward, P1
Ferguson, JJ8
Galvani, M1
De Vita, M1
Bassand, JP7
Hamm, C1
Budaj, A6
Eikelboom, JW4
Mehta, SR7
Afzal, R6
Chrolavicius, S5
Fox, KA6
Peters, RJ2
Joyner, CD4
Yusuf, S6
Colombo, A1
McLaurin, BT1
Cox, DA1
Pocock, SJ1
Ware, JA1
Manoukian, SV5
Lansky, AJ2
Moses, JW1
Yan, AT1
Yan, RT1
Huynh, T1
DeYoung, P1
Weeks, A1
Fitchett, DH1
Boden, WE2
Flather, M3
Avezum, A1
Piegas, LS1
Faxon, DP2
Widimsky, P2
Rupprecht, HJ2
Jolly, S1
Tonev, ST1
Spinler, SA3
Levine, GN2
Gallo, R1
Ducas, J1
Becker, RC2
Col, JJ3
Kruse, MW1
Lee, JJ1
Heer, T1
Juenger, C1
Gitt, AK1
Bauer, T1
Towae, F1
Zahn, R1
Senges, J1
Zeymer, U2
Bhatt, DL1
Franzosi, MG1
Martin, JL2
Fry, ET1
Martin, T1
Atherley, TH1
Martin, SS1
Slepian, MJ1
Karthikeyan, G1
Feit, F4
Pollack, CV6
Hoekstra, J1
Gersh, BJ3
Sambrook, J1
Palmer, S1
Ormanidhi, O1
Bakhai, A1
Weintraub, W1
Cristea, E1
Parise, H1
Hamon, M2
Mitrovska, S1
Jovanova, S1
Chan, MY1
Sun, LJ1
Pieper, KS6
Roe, MT4
Ou, FS1
Gibler, WB2
Peterson, ED2
Hollander, JE2
Gibson, CM3
Nadar, SK1
Goyal, D1
Shantsila, E1
Banerjee, P1
Lip, GY1
Roffi, M2
Eberli, FR1
Cequier, A1
Lincoff, MA1
Mann, T1
Drouet, L1
Bal dit Sollier, C1
Martin, J1
Jolly, SS1
Valentin, V1
Miller, CD2
Blomkalns, AL1
Brogan, GX1
Diercks, DB1
Peacock, WF1
Eikelboom, J1
Peters, R1
Mehta, S1
Anderson, JA1
Hirsh, J1
Johnston, M1
Walters, DL1
Ray, MJ1
Wood, P1
Perrin, EJ1
Bett, JH1
Aroney, CN1
Damman, P1
Hirsch, A1
Windhausen, F1
Tijssen, JG1
de Winter, RJ1
Schiele, F2
Meneveau, N1
Seronde, MF1
Descotes-Genon, V1
Dutheil, J1
Chopard, R1
Ecarnot, F1
Deal, EN1
Hollands, JM1
Lan, L1
Danchin, N1
Aïssaoui, N1
Bhattacharya, R1
Pani, A1
Dutta, D1
Basak, S1
Gangopadhyay, S1
Das Baksi, S1
Sarkar, RN1
Zhang, M1
Tsiatis, AA1
Davidian, M1
Yang, H1
Marian, AJ1
Furman, MI1
Michael Lincoff, A1
Hazen, SL1
Reist, CJ1
Gomes, M1
Ramacciotti, E1
Litinas, E1
Fareed, J1
Slepian, M1
Yaméogo, NV1
Mbaye, A1
Kagambèga, LJ1
Diack, B1
Pessinaba, S1
Hakim, R1
Ndiaye, MB1
Bodian, M1
Diao, M1
Sow, DD1
Kane, M1
Kane, A1
Lokhnygina, Y2
Hochman, JS1
Iqbal, Z1
Martí, V1
García-Picart, J1
Carballeira, L1
Carballo, S1
Carballo, D1
Keller, PF2
Baber, U1
Ng, FH2
Tunggal, P1
Chu, WM2
Lam, KF2
Li, A1
Chan, K1
Lau, YK2
Kng, C1
Keung, KK1
Kwan, A1
Wong, BC2
Silvain, J2
Beygui, F1
Barthélémy, O1
Pollack, C1
Goldstein, P1
Cayla, G1
Collet, JP1
Vicaut, E1
Montalescot, G2
James, S1
Kossovsky, M1
Mach, F1
Gaspoz, JM1
Pepe, C1
Machado, M1
Olimpio, A1
Ramos, R1
Murphy, SA1
Morrow, DA2
Van de Werf, F1
Menown, IB1
McCabe, CH1
Braunwald, E1
Eriksson, BI1
Dahl, OE1
Rosencher, N1
Kurth, AA1
van Dijk, CN1
Frostick, SP1
Kälebo, P1
Christiansen, AV1
Hantel, S1
Hettiarachchi, R1
Schnee, J1
Büller, HR1
Denardo, SJ1
Davis, KE1
Tcheng, JE1
Tricoci, P1
Berdan, LG1
Gulba, DC1
Newby, LK2
Richard-Lordereau, I1
Cadroy, Y1
Normand, SL1
Yeh, RW1
Wiviott, SD1
Giugliano, RP1
Shui, A1
Qin, J1
Scirica, B1
Bradner, JE1
Jang, IK1
Wong, SY1
Chang, CM1
Yang, Q1
Reist, C1
Chew, DP3
Huang, Z2
White, H1
Aylward, PG1
Kwa, AT1
Rogers, JH1
Melloni, C1
Chen, AY1
Szczech, LA1
Ebrahimi, R1
Attubato, MJ1
Bertrand, M1
Pocock, S1
Ware, J1
Barantke, M1
Bonnemeier, H1
Eggers, KM1
Lagerqvist, B1
Oldgren, J1
Venge, P1
Lindahl, B1
Goldman, MC1

Clinical Trials (9)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Safety and Efficacy of Low Molecular Weight Heparin Versus Rivaroxaban in Chinese Patients Hospitalized With Acute Coronary Syndrome(H-REPLACE): a Prospective, Randomized, Open-label, Active-controlled, Multicenter Trial[NCT03363035]Phase 42,055 participants (Actual)Interventional2018-01-15Completed
The ACUITY Trial: A Randomized Comparison of Angiomax (Bivalirudin) Versus Heparin (Unfractionated Heparin or Enoxaparin) in Patients Undergoing Early Invasive Management for Acute Coronary Syndromes Without ST-Segment Elevation[NCT00093158]Phase 313,800 participants Interventional2003-08-31Completed
A Prospective, Randomized, Open-Label, Multicenter Study in Patients Presenting With Acute Coronary Syndromes (ACS)[NCT00043784]Phase 38,000 participants Interventional2001-08-31Completed
A Phase I, Pharmacokinetic and Tolerability Study of Intravenous Unfractionated Heparin After Subcutaneous Enoxaparin 1mg/kg Bid Repeated Administration in Healthy Subjects[NCT00622115]Phase 172 participants (Actual)Interventional2007-07-31Completed
An International, Randomized, Double-blind Study Evaluating the Efficacy and Safety of Fondaparinux Versus Enoxaparin in the Acute Treatment of Unstable Angina/Non ST-segment Elevation MI Acute Coronary Syndromes[NCT00139815]Phase 320,078 participants (Actual)Interventional2003-04-30Completed
Influence of the Compression Method After Transradial Catheterization in Radial Artery[NCT02697526]274 participants (Actual)Interventional2007-01-31Completed
Famotidine Compared With Esomeprazole in the Prevention of Ulcer Complications in Patients With Acute Coronary Syndrome or Myocardial Infarction[NCT00683111]Phase 4500 participants (Anticipated)Interventional2008-07-31Completed
Optimizing the Anticoagulation Regimen of Enoxaparin During Percutaneous Coronary Intervention[NCT03145675]Phase 4378 participants (Actual)Interventional2017-05-12Completed
Beijing Tiantan Hospital,Capital Medical University.[NCT02317445]472 participants (Actual)Observational2008-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

17 reviews available for dalteparin and Acute Coronary Syndrome

ArticleYear
Update on the clinical use of the low-molecular-weight heparin, parnaparin.
    Vascular health and risk management, 2009, Volume: 5

    Topics: Acute Coronary Syndrome; Anticoagulants; Arterial Occlusive Diseases; Cardiovascular Diseases; Drug

2009
Choosing between Enoxaparin and Fondaparinux for the management of patients with acute coronary syndrome: A systematic review and meta-analysis.
    BMC cardiovascular disorders, 2017, 05-08, Volume: 17, Issue:1

    Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Chi-Square Distribution; Enoxaparin; Female; Fondapar

2017
Cardiovascular outcomes during treatment with dabigatran: comprehensive analysis of individual subject data by treatment.
    Vascular health and risk management, 2013, Volume: 9

    Topics: Acute Coronary Syndrome; Antithrombins; Atrial Fibrillation; Benzimidazoles; Chi-Square Distribution

2013
Anticoagulation and antiplatelet therapy in acute coronary syndromes.
    Cleveland Clinic journal of medicine, 2014, Volume: 81, Issue:2

    Topics: Acute Coronary Syndrome; Adenosine; Anticoagulants; Aspirin; Benzimidazoles; beta-Alanine; Clopidogr

2014
Antiplatelet and anticoagulation agents in acute coronary syndromes: what is the current status and what does the future hold?
    American heart journal, 2014, Volume: 168, Issue:5

    Topics: Acute Coronary Syndrome; Adenosine; Adenosine Monophosphate; Anticoagulants; Aspirin; Drug Therapy,

2014
Anticoagulants in ischemia-guided management of non-ST-elevation acute coronary syndromes.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:3

    Topics: Acute Coronary Syndrome; American Heart Association; Angina, Unstable; Anticoagulants; Clinical Tria

2017
Hospitals with and without percutaneous coronary intervention capability: considerations for treating acute coronary syndromes.
    The American journal of emergency medicine, 2009, Volume: 27, Issue:5

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Emerg

2009
Diabetes and acute coronary syndromes.
    Best practice & research. Clinical endocrinology & metabolism, 2009, Volume: 23, Issue:3

    Topics: Acute Coronary Syndrome; Anticoagulants; Aspirin; Blood Glucose; Clopidogrel; Diabetes Mellitus; Dia

2009
Pharmacologic therapy for non ST-segment elevation acute coronary syndromes: focus on antithrombotic therapy.
    Cardiovascular drugs and therapy, 2010, Volume: 24, Issue:4

    Topics: Acute Coronary Syndrome; Adenosine; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopido

2010
Use of low-molecular-weight heparins during percutaneous coronary intervention.
    The Journal of invasive cardiology, 2011, Volume: 23, Issue:1

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Animals; Anticoagulants; Cardiac Catheteriz

2011
Enoxaparin: a pharmacologic and clinical review.
    Expert opinion on pharmacotherapy, 2011, Volume: 12, Issue:7

    Topics: Acute Coronary Syndrome; Anticoagulants; Clinical Trials as Topic; Enoxaparin; Heparin, Low-Molecula

2011
Efficacy and safety of enoxaparin versus unfractionated heparin during percutaneous coronary intervention: systematic review and meta-analysis.
    BMJ (Clinical research ed.), 2012, Feb-03, Volume: 344

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Anticoagulants; Enoxaparin; Hemorrhage; Hep

2012
Efficacy and safety of the low-molecular weight heparin enoxaparin compared with unfractionated heparin across the acute coronary syndrome spectrum: a meta-analysis.
    European heart journal, 2007, Volume: 28, Issue:17

    Topics: Acute Coronary Syndrome; Antithrombins; Double-Blind Method; Drug Therapy, Combination; Enoxaparin;

2007
Efficacy and safety of fondaparinux in patients with acute coronary syndromes.
    Expert review of cardiovascular therapy, 2007, Volume: 5, Issue:6

    Topics: Acute Coronary Syndrome; Aged; Dose-Response Relationship, Drug; Drug Administration Schedule; Enoxa

2007
Current update on glycoprotein IIb-IIIa and direct thrombin inhibition in percutaneous coronary intervention for non-ST elevation acute coronary syndromes: balancing bleeding risk and antiplatelet efficacy.
    Journal of interventional cardiology, 2008, Volume: 21, Issue:2

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitors; A

2008
Factor Xa inactivation in acute coronary syndrome.
    Current pharmaceutical design, 2008, Volume: 14, Issue:12

    Topics: Acute Coronary Syndrome; Angina, Unstable; Anticoagulants; Enoxaparin; Factor Xa Inhibitors; Fondapa

2008
Dalteparin as the primary low-molecular-weight heparin on a hospital formulary.
    Connecticut medicine, 2009, Volume: 73, Issue:1

    Topics: Acute Coronary Syndrome; Anticoagulants; Dalteparin; Fibrinolytic Agents; Formularies, Hospital as T

2009

Trials

41 trials available for dalteparin and Acute Coronary Syndrome

ArticleYear
[Efficacy comparison with low and high dose nadroparin for patients with acute coronary syndrome underwent percutaneous coronary intervention].
    Zhonghua xin xue guan bing za zhi, 2008, Volume: 36, Issue:6

    Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Female; Humans; Male;

2008
Comparison of safety and efficacy between fondaparinux and nadroparin in non-ST elevation acute coronary syndromes.
    Chinese medical journal, 2011, Volume: 124, Issue:6

    Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Female; Fibrinolytic Agents; Fondaparinux; Humans; Ma

2011
Effect of Rivaroxaban vs Enoxaparin on Major Cardiac Adverse Events and Bleeding Risk in the Acute Phase of Acute Coronary Syndrome: The H-REPLACE Randomized Equivalence and Noninferiority Trial.
    JAMA network open, 2023, 02-01, Volume: 6, Issue:2

    Topics: Acute Coronary Syndrome; Aged; Aspirin; Enoxaparin; Female; Hemorrhage; Humans; Male; Platelet Aggre

2023
Rationale and Design of the H-REPLACE Study: Safety and Efficacy of LMWH Versus Rivaroxaban in ChinEse Patients HospitaLized with Acute Coronary SyndromE.
    Cardiovascular drugs and therapy, 2022, Volume: 36, Issue:1

    Topics: Acute Coronary Syndrome; Anticoagulants; Asian People; Dose-Response Relationship, Drug; Enoxaparin;

2022
Use of the CRUSADE bleeding risk score in the prediction of major bleeding for patients with acute coronary syndrome receiving enoxaparin in Thailand.
    Heart, lung & circulation, 2014, Volume: 23, Issue:11

    Topics: Acute Coronary Syndrome; Enoxaparin; Female; Fibrinolytic Agents; Hemorrhage; Humans; Male; Middle A

2014
Impact of anticoagulation regimen prior to revascularization in patients with non-ST-segment elevation acute coronary syndromes: The ACUITY trial.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2016, Volume: 88, Issue:2

    Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Antithrombins; Coronary Artery Bypass; Drug Therapy,

2016
Eptifibatide infusion versus placebo in high risk patients with non-ST segment elevation acute coronary syndromes managed with urgent coronary artery bypass graft surgery. A prospective multicenter randomized placebo-controlled clinical trial.
    The Journal of cardiovascular surgery, 2016, Volume: 57, Issue:1

    Topics: Acute Coronary Syndrome; Aspirin; Coronary Artery Bypass; Enoxaparin; Eptifibatide; Female; Fibrinol

2016
Outcomes in elderly patients with acute coronary syndromes randomized to enoxaparin vs. unfractionated heparin: results from the SYNERGY trial.
    European heart journal, 2008, Volume: 29, Issue:15

    Topics: Acute Coronary Syndrome; Age Factors; Aged; Anticoagulants; Coronary Angiography; Cross-Over Studies

2008
Smoking status and antithrombin therapy in patients with non-ST-segment elevation acute coronary syndrome.
    American heart journal, 2008, Volume: 156, Issue:1

    Topics: Acute Coronary Syndrome; Adult; Age Factors; Aged; Antithrombins; Dose-Response Relationship, Drug;

2008
[The ACUITY trial: one-year results].
    Giornale italiano di cardiologia (2006), 2008, Volume: 9, Issue:6

    Topics: Acute Coronary Syndrome; Anticoagulants; Enoxaparin; Hirudins; Humans; Peptide Fragments; Platelet G

2008
Improving clinical outcomes by reducing bleeding in patients with non-ST-elevation acute coronary syndromes.
    European heart journal, 2009, Volume: 30, Issue:6

    Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Enoxaparin; Female; Fondaparinux; Hemorrhage; Humans;

2009
Safety and efficacy of bivalirudin with and without glycoprotein IIb/IIIa inhibitors in patients with acute coronary syndromes undergoing percutaneous coronary intervention 1-year results from the ACUITY (Acute Catheterization and Urgent Intervention Tria
    Journal of the American College of Cardiology, 2008, Sep-02, Volume: 52, Issue:10

    Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagula

2008
Bleeding and outcome in acute coronary syndrome: insights from continuous electrocardiogram monitoring in the Integrilin and Enoxaparin Randomized Assessment of Acute Coronary Syndrome Treatment (INTERACT) Trial.
    American heart journal, 2008, Volume: 156, Issue:4

    Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Electrocardiography, Ambulatory; Enoxaparin; Eptifiba

2008
Antithrombotic therapy with fondaparinux in relation to interventional management strategy in patients with ST- and non-ST-segment elevation acute coronary syndromes: an individual patient-level combined analysis of the Fifth and Sixth Organization to Ass
    Circulation, 2008, Nov-11, Volume: 118, Issue:20

    Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Double-Blind Method;

2008
Fondaparinux compared to enoxaparin in patients with acute coronary syndromes without ST-segment elevation: outcomes and treatment effect across different levels of risk.
    American heart journal, 2009, Volume: 157, Issue:3

    Topics: Acute Coronary Syndrome; Anticoagulants; Enoxaparin; Fondaparinux; Hemorrhage; Humans; Polysaccharid

2009
The pharmacodynamics of enoxaparin in percutaneous coronary intervention with precise rapid enoxaparin loading (PEPCI-PRE study).
    Journal of thrombosis and thrombolysis, 2009, Volume: 28, Issue:2

    Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Enoxaparin; Factor Xa

2009
Advanced age, antithrombotic strategy, and bleeding in non-ST-segment elevation acute coronary syndromes: results from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial.
    Journal of the American College of Cardiology, 2009, Mar-24, Volume: 53, Issue:12

    Topics: Acute Coronary Syndrome; Aged; Aging; Angioplasty, Balloon, Coronary; Anticoagulants; Coronary Arter

2009
Fondaparinux versus Enoxaparin in non-ST-elevation acute coronary syndromes: short-term cost and long-term cost-effectiveness using data from the Fifth Organization to Assess Strategies in Acute Ischemic Syndromes Investigators (OASIS-5) trial.
    American heart journal, 2009, Volume: 157, Issue:5

    Topics: Acute Coronary Syndrome; Anticoagulants; Cost-Benefit Analysis; Electrocardiography; Enoxaparin; Fac

2009
Impact of gender and antithrombin strategy on early and late clinical outcomes in patients with non-ST-elevation acute coronary syndromes (from the ACUITY trial).
    The American journal of cardiology, 2009, May-01, Volume: 103, Issue:9

    Topics: Acute Coronary Syndrome; Adult; Age Factors; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary

2009
Low-molecular weight heparin enoxaparin in the treatment of acute coronary syndromes without ST segment elevation.
    Bratislavske lekarske listy, 2009, Volume: 110, Issue:1

    Topics: Acute Coronary Syndrome; Anticoagulants; Electrocardiography; Enoxaparin; Heparin; Humans; Survival

2009
Prevalence, predictors, and impact of conservative medical management for patients with non-ST-segment elevation acute coronary syndromes who have angiographically documented significant coronary disease.
    JACC. Cardiovascular interventions, 2008, Volume: 1, Issue:4

    Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Coronary Angiography;

2008
Choice of arterial access site and outcomes in patients with acute coronary syndromes managed with an early invasive strategy: the ACUITY trial.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2009, Volume: 5, Issue:1

    Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagula

2009
Adding intravenous unfractionated heparin to standard enoxaparin causes excessive anticoagulation not detected by activated clotting time: results of the STACK-on to ENOXaparin (STACKENOX) study.
    American heart journal, 2009, Volume: 158, Issue:2

    Topics: Acute Coronary Syndrome; Adult; Blood Coagulation; Enoxaparin; Female; Heparin; Humans; Male; Middle

2009
Efficacy and safety of fondaparinux versus enoxaparin in patients with acute coronary syndromes treated with glycoprotein IIb/IIIa inhibitors or thienopyridines: results from the OASIS 5 (Fifth Organization to Assess Strategies in Ischemic Syndromes) tria
    Journal of the American College of Cardiology, 2009, Jul-28, Volume: 54, Issue:5

    Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Drug Therapy, Combination; Enoxaparin; Female; Fondap

2009
Safety and efficacy of bivalirudin in high-risk patients admitted through the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2009, Volume: 16, Issue:8

    Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Chi-Square Distribution; Comorbidity; Emergency Servi

2009
Relationship between baseline haemoglobin and major bleeding complications in acute coronary syndromes.
    European heart journal, 2010, Volume: 31, Issue:1

    Topics: Acute Coronary Syndrome; Aged; Analysis of Variance; Angioplasty, Balloon, Coronary; Anticoagulants;

2010
Relationship between baseline haemoglobin and major bleeding complications in acute coronary syndromes.
    European heart journal, 2010, Volume: 31, Issue:1

    Topics: Acute Coronary Syndrome; Aged; Analysis of Variance; Angioplasty, Balloon, Coronary; Anticoagulants;

2010
Relationship between baseline haemoglobin and major bleeding complications in acute coronary syndromes.
    European heart journal, 2010, Volume: 31, Issue:1

    Topics: Acute Coronary Syndrome; Aged; Analysis of Variance; Angioplasty, Balloon, Coronary; Anticoagulants;

2010
Relationship between baseline haemoglobin and major bleeding complications in acute coronary syndromes.
    European heart journal, 2010, Volume: 31, Issue:1

    Topics: Acute Coronary Syndrome; Aged; Analysis of Variance; Angioplasty, Balloon, Coronary; Anticoagulants;

2010
Comparison of the anticoagulant intensities of fondaparinux and enoxaparin in the Organization to Assess Strategies in Acute Ischemic Syndromes (OASIS)-5 trial.
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:2

    Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Blood Coagulation; Dose-Response Relationship, Drug;

2010
High-dose tirofiban with enoxaparin and inflammatory markers in high-risk percutaneous intervention.
    European journal of clinical investigation, 2010, Volume: 40, Issue:2

    Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon; Anticoagulants; Biomarkers; Blood Coagulation F

2010
5-year clinical outcomes in the ICTUS (Invasive versus Conservative Treatment in Unstable coronary Syndromes) trial a randomized comparison of an early invasive versus selective invasive management in patients with non-ST-segment elevation acute coronary
    Journal of the American College of Cardiology, 2010, Mar-02, Volume: 55, Issue:9

    Topics: Abciximab; Acute Coronary Syndrome; Adolescent; Adult; Aged; Aged, 80 and over; Angina, Unstable; An

2010
Enoxaparin 0.3 mg/kg IV supplement for patients transitioning to PCI after subcutaneous enoxaparin therapy for NSTE ACS: a subgroup analysis from the SYNERGY trial.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2010, May-01, Volume: 75, Issue:6

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Combined Modality Therapy; Enoxaparin; Fema

2010
Randomised controlled trial evaluating the role of tirofiban in high-risk non-ST elevation acute coronary syndromes: an East Indian perspective.
    Singapore medical journal, 2010, Volume: 51, Issue:7

    Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Administ

2010
Heparin-associated anti-Xa activity and platelet-derived prothrombotic and proinflammatory biomarkers in moderate to high-risk patients with acute coronary syndrome.
    Journal of thrombosis and thrombolysis, 2011, Volume: 31, Issue:2

    Topics: Acute Coronary Syndrome; Aged; Biomarkers; Blood Coagulation Factor Inhibitors; Blood Platelets; CD4

2011
The impact of postrandomization crossover of therapy in acute coronary syndromes care.
    Circulation. Cardiovascular quality and outcomes, 2011, Volume: 4, Issue:2

    Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Cross-Over Studies; Enoxaparin; Female; Hemorrhage; H

2011
Esomeprazole compared with famotidine in the prevention of upper gastrointestinal bleeding in patients with acute coronary syndrome or myocardial infarction.
    The American journal of gastroenterology, 2012, Volume: 107, Issue:3

    Topics: Acute Coronary Syndrome; Aged; Anti-Ulcer Agents; Aspirin; Chi-Square Distribution; Clopidogrel; Dou

2012
Oral dabigatran etexilate vs. subcutaneous enoxaparin for the prevention of venous thromboembolism after total knee replacement: the RE-MODEL randomized trial.
    Journal of thrombosis and haemostasis : JTH, 2007, Volume: 5, Issue:11

    Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Arthroplasty, Replacement, Knee; Benzimidazoles; Clin

2007
Effect of thrombocytopenia on outcomes following treatment with either enoxaparin or unfractionated heparin in patients presenting with acute coronary syndromes.
    The American journal of cardiology, 2007, Dec-15, Volume: 100, Issue:12

    Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Comorbidity; Enoxaparin; Female; Heparin; Humans; Inc

2007
Prediction of one-year survival in high-risk patients with acute coronary syndromes: results from the SYNERGY trial.
    Journal of general internal medicine, 2008, Volume: 23, Issue:3

    Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Cause of Death; Coronary Angiography; Dose-Respons

2008
Patients with non-ST-elevation acute coronary syndromes undergoing coronary artery bypass grafting in the modern era of antithrombotic therapy.
    American heart journal, 2008, Volume: 155, Issue:2

    Topics: Acute Coronary Syndrome; Aged; Clopidogrel; Coronary Artery Bypass; Electrocardiography; Enoxaparin;

2008
Safety and efficacy of bivalirudin monotherapy in patients with diabetes mellitus and acute coronary syndromes: a report from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial.
    Journal of the American College of Cardiology, 2008, Apr-29, Volume: 51, Issue:17

    Topics: Acute Coronary Syndrome; Acute Disease; Adult; Aged; Aged, 80 and over; Anticoagulants; Cardiac Cath

2008
Safety and efficacy of switching from either unfractionated heparin or enoxaparin to bivalirudin in patients with non-ST-segment elevation acute coronary syndromes managed with an invasive strategy: results from the ACUITY (Acute Catheterization and Urgen
    Journal of the American College of Cardiology, 2008, May-06, Volume: 51, Issue:18

    Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Anticoagulants; Enoxaparin; Female; Heart C

2008
Pathophysiologic mechanisms of persistent cardiac troponin I elevation in stabilized patients after an episode of acute coronary syndrome.
    American heart journal, 2008, Volume: 156, Issue:3

    Topics: Acute Coronary Syndrome; Aged; Biomarkers; Dalteparin; Echocardiography; Female; Fibrinolytic Agents

2008

Other Studies

40 other studies available for dalteparin and Acute Coronary Syndrome

ArticleYear
[Effectiveness and safety of nadroparin in acute coronary syndrome].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2007, Volume: 29, Issue:4

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon; Anticoagulants; Factor Xa Inhibitors; Humans; Nadropa

2007
[Massive pulmonary embolism mimicking ST-elevation acute coronary syndrome successfully treated with hybrid therapy in a trauma patient receiving nadroparin: diagnostic and therapeutic dilemmas].
    Kardiologia polska, 2007, Volume: 65, Issue:10

    Topics: Acute Coronary Syndrome; Angiocardiography; Angioplasty, Balloon; Diagnosis, Differential; Drug Ther

2007
Factors associated with bleeding events from enoxaparin used for patients with acute coronary syndrome.
    BMC cardiovascular disorders, 2023, 05-06, Volume: 23, Issue:1

    Topics: Acute Coronary Syndrome; Anticoagulants; Enoxaparin; Hemorrhage; Humans; Retrospective Studies; Thai

2023
Safety and efficacy of bivalirudin monotherapy in patients with non-ST-segment elevation acute coronary syndromes with positive biomarkers undergoing percutaneous coronary intervention: a report from the Acute Catheterization and Urgent Intervention Triag
    Coronary artery disease, 2020, Volume: 31, Issue:1

    Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Antithrombins; Creatine Kinase, MB Form; Enoxaparin;

2020
Comparative Effectiveness and Costs of Enoxaparin Monotherapy Versus Unfractionated Heparin Monotherapy in Treating Acute Coronary Syndrome.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2021, Volume: 21, Issue:1

    Topics: Acute Coronary Syndrome; Adult; Age Factors; Aged; Aged, 80 and over; Anticoagulants; Comorbidity; E

2021
Enoxaparin induced reactive thrombocytosis: a rare adverse drug reaction.
    Journal of basic and clinical physiology and pharmacology, 2020, Jun-24, Volume: 31, Issue:5

    Topics: Acute Coronary Syndrome; Anticoagulants; Enoxaparin; Female; Humans; Injections, Subcutaneous; Middl

2020
Fondaparinux versus enoxaparin in the contemporary management of non-ST-elevation acute coronary syndromes. Insights from a multicenter registry.
    International journal of cardiology, 2021, 06-01, Volume: 332

    Topics: Acute Coronary Syndrome; Anticoagulants; Enoxaparin; Fondaparinux; Humans; Polysaccharides; Prospect

2021
Safety and efficacy of intense antithrombotic treatment and percutaneous coronary intervention deferral in patients with large intracoronary thrombus.
    The American journal of cardiology, 2013, Jun-15, Volume: 111, Issue:12

    Topics: Acute Coronary Syndrome; Angiography; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopi

2013
Prognostic significance of bleeding location and severity among patients with acute coronary syndromes.
    JACC. Cardiovascular interventions, 2013, Volume: 6, Issue:7

    Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Blood Loss, Surgical; Coronary Artery Bypass; Enoxapa

2013
Cost-Effectiveness Analysis of Fondaparinux vs Enoxaparin in Non-ST Elevation Acute Coronary Syndrome in Thailand.
    Heart, lung & circulation, 2015, Volume: 24, Issue:9

    Topics: Acute Coronary Syndrome; Aged; Costs and Cost Analysis; Enoxaparin; Female; Fondaparinux; Humans; Ma

2015
Elucidating the use of enoxaparin in non-ST-elevation acute coronary syndromes (NSTE-ACS).
    Evidence-based medicine, 2016, Volume: 21, Issue:1

    Topics: Acute Coronary Syndrome; Administration, Intravenous; Anticoagulants; Enoxaparin; Humans; Injections

2016
Cost-effectiveness of fondaparinux versus enoxaparin in non-ST-elevation acute coronary syndrome in Canada (OASIS-5).
    BMC cardiovascular disorders, 2015, Dec-29, Volume: 15

    Topics: Acute Coronary Syndrome; Anticoagulants; Canada; Cost-Benefit Analysis; Decision Support Techniques;

2015
Fondaparinux versus Enoxaparin - Which is the Best Anticoagulant for Acute Coronary Syndrome? - Brazilian Registry Data.
    Arquivos brasileiros de cardiologia, 2016, Volume: 107, Issue:3

    Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Brazil; Enoxaparin; Female; Fondaparinux; Hemorrhage;

2016
Guidelines for anticoagulant use in acute coronary syndromes.
    Lancet (London, England), 2008, Aug-16, Volume: 372, Issue:9638

    Topics: Acute Coronary Syndrome; Anticoagulants; Enoxaparin; Europe; Humans; Practice Guidelines as Topic

2008
Obesity in patients with non-ST-segment elevation acute coronary syndromes: results from the SYNERGY trial.
    International journal of cardiology, 2010, Mar-04, Volume: 139, Issue:2

    Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Anticoagulants; Body Mass Index; Comorbidity; Data

2010
Bias in AJHP supplements.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2008, Dec-15, Volume: 65, Issue:24

    Topics: Acute Coronary Syndrome; Bias; Conflict of Interest; Drug Industry; Enoxaparin; Fibrinolytic Agents;

2008
Efficacy and safety of optimized antithrombotic therapy with aspirin, clopidogrel and enoxaparin in patients with non-ST segment elevation acute coronary syndromes in clinical practice.
    Journal of thrombosis and thrombolysis, 2009, Volume: 28, Issue:3

    Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Drug Evaluation; Drug Therapy, Combination; Dru

2009
The pain and the gain of treating patients with acute coronary syndromes-can the two be separated?
    American heart journal, 2009, Volume: 157, Issue:3

    Topics: Acute Coronary Syndrome; Anticoagulants; Enoxaparin; Fondaparinux; Hemorrhage; Humans; Myocardial Is

2009
Fondaparinux in the treatment of acute coronary syndromes: evidence from OASIS 5 and 6.
    Expert review of cardiovascular therapy, 2009, Volume: 7, Issue:3

    Topics: Acute Coronary Syndrome; Anticoagulants; Double-Blind Method; Enoxaparin; Factor Xa Inhibitors; Fond

2009
Weight-based dosing of enoxaparin in obese patients with non-ST-segment elevation acute coronary syndromes: results from the CRUSADE initiative.
    Pharmacotherapy, 2009, Volume: 29, Issue:6

    Topics: Acute Coronary Syndrome; Aged; Angina, Unstable; Anticoagulants; Body Weight; Cohort Studies; Enoxap

2009
Fondaparinux: an overview.
    Expert review of cardiovascular therapy, 2009, Volume: 7, Issue:6

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Anticoagulants; Drug Interactions; Enoxapar

2009
Routine use of fondaparinux in acute coronary syndromes: a 2-year multicenter experience.
    American heart journal, 2010, Volume: 159, Issue:2

    Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Enoxaparin; Female; Fondaparinux; Heparin; Humans; Ma

2010
Contraindicated medication use in dialysis patients.
    JAMA, 2010, Apr-21, Volume: 303, Issue:15

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Contraindications; Drug Labeling; Enoxapari

2010
Fondaparinux and acute coronary syndromes: update on the OASIS 5-6 studies.
    Vascular health and risk management, 2010, Apr-15, Volume: 6

    Topics: Acute Coronary Syndrome; Anticoagulants; Catheterization; Enoxaparin; Fondaparinux; Hirudins; Humans

2010
Inference on treatment effects from a randomized clinical trial in the presence of premature treatment discontinuation: the SYNERGY trial.
    Biostatistics (Oxford, England), 2011, Volume: 12, Issue:2

    Topics: Acute Coronary Syndrome; Algorithms; Computer Simulation; Endpoint Determination; Enoxaparin; Hemorr

2011
[Concerns on generic enoxaparin use in acute coronary syndrome].
    Arquivos brasileiros de cardiologia, 2010, Volume: 95, Issue:4

    Topics: Acute Coronary Syndrome; Anticoagulants; Clinical Trials as Topic; Drug Approval; Drugs, Generic; En

2010
[Pulmonary embolism mimicking acute anterior myocardial infarction: diagnostic trap].
    Annales de cardiologie et d'angeiologie, 2011, Volume: 60, Issue:3

    Topics: Acenocoumarol; Acute Coronary Syndrome; Anterior Wall Myocardial Infarction; Anticoagulants; Coronar

2011
[Acute coronary syndrome due to distal embolization of a thrombus located in the left main coronary artery].
    Revista espanola de cardiologia, 2011, Volume: 64, Issue:7

    Topics: Acute Coronary Syndrome; Angina Pectoris; Angiography; Anticoagulants; Coronary Thrombosis; Electroc

2011
[Specificities of diabetes in acute coronary syndromes].
    Revue medicale suisse, 2011, Jun-01, Volume: 7, Issue:297

    Topics: Acute Coronary Syndrome; Algorithms; Angioplasty; Anti-Inflammatory Agents, Non-Steroidal; Clopidogr

2011
Acute coronary syndromes: Antithrombotics in ACS--moving beyond unfractionated heparin.
    Nature reviews. Cardiology, 2011, Sep-27, Volume: 8, Issue:11

    Topics: Acute Coronary Syndrome; Anticoagulants; Antithrombins; Enoxaparin; Fibrinolytic Agents; Heparin; Hi

2011
Enoxaparin for anticoagulation in patients undergoing percutaneous coronary intervention.
    BMJ (Clinical research ed.), 2012, Feb-03, Volume: 344

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Anticoagulants; Enoxaparin; Heparin; Humans

2012
Fondaparinux versus enoxaprin in the management of acute coronary syndromes in Switzerland: A cost comparison analysis.
    Swiss medical weekly, 2012, Volume: 142

    Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Costs and Cost Analysis; Drug Costs; Enoxaparin; Fact

2012
Anticoagulant for primary percutaneous coronary intervention - the last dance for unfractionated heparin?
    Archives of cardiovascular diseases, 2012, Volume: 105, Issue:5

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Anticoagulants; Coronary Thrombosis; Enoxap

2012
Cost-effectiveness of fondaparinux in patients with acute coronary syndrome without ST-segment elevation.
    Arquivos brasileiros de cardiologia, 2012, Volume: 99, Issue:1

    Topics: Acute Coronary Syndrome; Anticoagulants; Brazil; Cost-Benefit Analysis; Enoxaparin; Female; Fondapar

2012
Effectiveness and safety of reduced-dose enoxaparin in non-ST-segment elevation acute coronary syndrome followed by antiplatelet therapy alone for percutaneous coronary intervention.
    The American journal of cardiology, 2007, Nov-01, Volume: 100, Issue:9

    Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Aspirin; Atherectomy, Coronary; Clopidogrel; Coronary

2007
Time to coronary angiography and outcomes among patients with high-risk non ST-segment elevation acute coronary syndromes: results from the SYNERGY trial.
    Circulation, 2007, Dec-04, Volume: 116, Issue:23

    Topics: Acute Coronary Syndrome; Aged; Blood Transfusion; Coronary Angiography; Enoxaparin; Female; Fibrinol

2007
Evaluating the optimal timing of angiography: landmark or off the mark?
    Circulation, 2007, Dec-04, Volume: 116, Issue:23

    Topics: Acute Coronary Syndrome; Aged; Blood Transfusion; Coronary Angiography; Enoxaparin; Female; Fibrinol

2007
Gastrointestinal bleeding in patients receiving a combination of aspirin, clopidogrel, and enoxaparin in acute coronary syndrome.
    The American journal of gastroenterology, 2008, Volume: 103, Issue:4

    Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clopidogrel; Drug

2008
Cockcroft-Gault versus modification of diet in renal disease: importance of glomerular filtration rate formula for classification of chronic kidney disease in patients with non-ST-segment elevation acute coronary syndromes.
    Journal of the American College of Cardiology, 2008, Mar-11, Volume: 51, Issue:10

    Topics: Acute Coronary Syndrome; Age Factors; Aged; Creatinine; Enoxaparin; Female; Fibrinolytic Agents; Glo

2008
Coronary artery bypass surgery in patients with acute coronary syndromes is difficult to predict.
    American heart journal, 2008, Volume: 155, Issue:5

    Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Coronary Artery Bypass; Enoxaparin; Forecasting; Huma

2008