dalteparin has been researched along with Acute Brain Injuries in 20 studies
Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The authors hypothesize that early chemoprophylaxis in patients with TBI is safe and efficacious." | 2.78 | Safety and efficacy of early thromboembolism chemoprophylaxis after intracranial hemorrhage from traumatic brain injury. ( Barnes, SL; Farooqui, A; Hiser, B; Litofsky, NS, 2013) |
| "Multiple studies have addressed deep vein thrombosis chemoprophylaxis timing in traumatic brain injuries." | 2.52 | Timing for deep vein thrombosis chemoprophylaxis in traumatic brain injury: an evidence-based review. ( Abdel-Aziz, H; Dunham, CM; Hileman, BM; Malik, RJ, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 15 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giannakaki, V | 1 |
| Triantafyllou, T | 1 |
| Drossos, D | 1 |
| Papapetrou, K | 1 |
| Farooqui, A | 1 |
| Hiser, B | 1 |
| Barnes, SL | 1 |
| Litofsky, NS | 1 |
| Pastorek, RA | 1 |
| Cripps, MW | 1 |
| Bernstein, IH | 1 |
| Scott, WW | 1 |
| Madden, CJ | 2 |
| Rickert, KL | 1 |
| Wolf, SE | 2 |
| Phelan, HA | 2 |
| Daley, MJ | 1 |
| Ali, S | 1 |
| Brown, CV | 1 |
| Abdel-Aziz, H | 1 |
| Dunham, CM | 1 |
| Malik, RJ | 1 |
| Hileman, BM | 1 |
| Li, S | 2 |
| Marks, JA | 1 |
| Eisenstadt, R | 2 |
| Kumasaka, K | 2 |
| Samadi, D | 1 |
| Johnson, VE | 2 |
| Holena, DN | 1 |
| Allen, SR | 1 |
| Browne, KD | 2 |
| Smith, DH | 2 |
| Pascual, JL | 2 |
| Marks, J | 1 |
| Nagata, K | 1 |
| Reiff, DA | 1 |
| Haricharan, RN | 1 |
| Bullington, NM | 1 |
| Griffin, RL | 1 |
| McGwin, G | 1 |
| Rue, LW | 1 |
| Dudley, RR | 1 |
| Aziz, I | 1 |
| Bonnici, A | 1 |
| Saluja, RS | 1 |
| Lamoureux, J | 1 |
| Kalmovitch, B | 1 |
| Gursahaney, A | 1 |
| Razek, T | 1 |
| Maleki, M | 1 |
| Marcoux, J | 1 |
| Salottolo, K | 1 |
| Offner, P | 1 |
| Levy, AS | 1 |
| Mains, CW | 1 |
| Slone, DS | 1 |
| Bar-Or, D | 1 |
| Sen, O | 1 |
| Sonmez, E | 1 |
| Cekinmez, M | 1 |
| Ozen, O | 1 |
| Caner, H | 1 |
| Minshall, CT | 1 |
| Eriksson, EA | 1 |
| Leon, SM | 1 |
| Doben, AR | 1 |
| McKinzie, BP | 1 |
| Fakhry, SM | 1 |
| Župan, Ž | 1 |
| Pilipović, K | 1 |
| Dangubić, B | 1 |
| Frković, V | 1 |
| Šustić, A | 1 |
| Župan, G | 1 |
| Broderick, PA | 1 |
| Kolodny, EH | 1 |
| Norwood, SH | 1 |
| Aldy, K | 1 |
| Brakenridge, SC | 1 |
| Eastman, AL | 1 |
| Nakonezny, PA | 1 |
| Yang, L | 1 |
| Chason, DP | 1 |
| Arbique, GM | 1 |
| Berne, J | 1 |
| Minei, JP | 1 |
| Ibrahim, A | 1 |
| Ashkan, K | 1 |
| Smith, M | 1 |
| Watkins, L | 1 |
| Wahl, F | 2 |
| Grosjean-Piot, O | 2 |
| Bareyre, F | 1 |
| Uzan, A | 2 |
| Stutzmann, JM | 2 |
| Mary, V | 1 |
| Pratt, J | 1 |
| Kleindienst, A | 1 |
| Harvey, HB | 1 |
| Mater, E | 1 |
| Bronst, J | 1 |
| Flack, J | 1 |
| Herenz, K | 1 |
| Haupt, WF | 1 |
| Schön, R | 1 |
| Ciapetti, M | 1 |
| Circelli, A | 1 |
| Zagli, G | 1 |
| Migliaccio, ML | 1 |
| Spina, R | 1 |
| Alessi, A | 1 |
| Acquafresca, M | 1 |
| Bartolini, M | 1 |
| Peris, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Improving Outcome in Subarachnoid Hemorrhage wIth Nadroparine[NCT04507178] | Phase 2 | 100 participants (Anticipated) | Interventional | 2022-02-02 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for dalteparin and Acute Brain Injuries
| Article | Year |
|---|---|
Post-Traumatic Bifrontoparietal Extradural Hematoma with Superior Sagittal Sinus Detachment: A Case Report and Review of the Literature.
Topics: Adult; Anticoagulants; Anticonvulsants; Brain Injuries; Drug Therapy, Combination; Hematoma, Epidura | 2016 |
Timing for deep vein thrombosis chemoprophylaxis in traumatic brain injury: an evidence-based review.
Topics: Anticoagulants; Brain Injuries; Enoxaparin; Humans; Intracranial Hemorrhages; Risk Factors; Venous T | 2015 |
Neuroprotective profile of enoxaparin, a low molecular weight heparin, in in vivo models of cerebral ischemia or traumatic brain injury in rats: a review.
Topics: Animals; Anticoagulants; Brain Edema; Brain Injuries; Brain Ischemia; Cognition Disorders; Enoxapari | 2002 |
2 trials available for dalteparin and Acute Brain Injuries
| Article | Year |
|---|---|
Safety and efficacy of early thromboembolism chemoprophylaxis after intracranial hemorrhage from traumatic brain injury.
Topics: Adult; Aged; Anticoagulants; Brain Injuries; Chemoprevention; Clinical Protocols; Cohort Studies; En | 2013 |
A randomized, double-blinded, placebo-controlled pilot trial of anticoagulation in low-risk traumatic brain injury: The Delayed Versus Early Enoxaparin Prophylaxis I (DEEP I) study.
Topics: Adult; Anticoagulants; Brain Injuries; Double-Blind Method; Enoxaparin; Female; Humans; Intracranial | 2012 |
15 other studies available for dalteparin and Acute Brain Injuries
| Article | Year |
|---|---|
The Parkland Protocol's modified Berne-Norwood criteria predict two tiers of risk for traumatic brain injury progression.
Topics: Adult; Aged; Brain Injuries; Clinical Protocols; Disease Progression; Enoxaparin; Female; Fibrinolyt | 2014 |
Late venous thromboembolism prophylaxis after craniotomy in acute traumatic brain injury.
Topics: Adult; Anticoagulants; Brain Injuries; Craniotomy; Enoxaparin; Female; Hospital Mortality; Humans; M | 2015 |
Enoxaparin ameliorates post-traumatic brain injury edema and neurologic recovery, reducing cerebral leukocyte endothelial interactions and vessel permeability in vivo.
Topics: Animals; Anticoagulants; Brain Edema; Brain Injuries; Endothelium, Vascular; Enoxaparin; Leukocytes; | 2015 |
Does enoxaparin interfere with HMGB1 signaling after TBI? A potential mechanism for reduced cerebral edema and neurologic recovery.
Topics: Animals; Antibodies, Monoclonal; Anticoagulants; Brain; Brain Edema; Brain Injuries; Cerebrovascular | 2016 |
Traumatic brain injury is associated with the development of deep vein thrombosis independent of pharmacological prophylaxis.
Topics: Adult; Age Distribution; Analysis of Variance; Anticoagulants; Brain Injuries; Chi-Square Distributi | 2009 |
Early venous thromboembolic event prophylaxis in traumatic brain injury with low-molecular-weight heparin: risks and benefits.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Brain Injuries; Chi-Square Distribution; | 2010 |
Interrupted pharmocologic thromboprophylaxis increases venous thromboembolism in traumatic brain injury.
Topics: Anticoagulants; Brain Injuries; Chi-Square Distribution; Enoxaparin; Female; Glasgow Coma Scale; Hep | 2011 |
Antithrombin III and enoxaparin treatment inhibit contusion-triggered cell death, inflammation, hemorrhage and apoptosis after severe traumatic brain injury in rats.
Topics: Animals; Anticoagulants; Antithrombin III; Antithrombins; Apoptosis; Brain Injuries; Disease Models, | 2011 |
Safety and efficacy of heparin or enoxaparin prophylaxis in blunt trauma patients with a head abbreviated injury severity score >2.
Topics: Abbreviated Injury Scale; Anticoagulants; Brain Injuries; Disease Progression; Enoxaparin; Heparin; | 2011 |
Effects of enoxaparin in the rat hippocampus following traumatic brain injury.
Topics: Animals; Anticoagulants; Apoptosis; Brain Injuries; Caspase 3; Enoxaparin; Glial Fibrillary Acidic P | 2011 |
Biosensors for brain trauma and dual laser doppler flowmetry: enoxaparin simultaneously reduces stroke-induced dopamine and blood flow while enhancing serotonin and blood flow in motor neurons of brain, in vivo.
Topics: Animals; Anticoagulants; Biosensing Techniques; Blood Flow Velocity; Brain Injuries; Dopamine; Elect | 2011 |
Anticoagulation in a head-injured patient.
Topics: Accidental Falls; Anticoagulants; Brain Injuries; Cerebral Hemorrhage; Contraindications; Enoxaparin | 2003 |
Enoxaparin reduces brain edema, cerebral lesions, and improves motor and cognitive impairments induced by a traumatic brain injury in rats.
Topics: Animals; Anticoagulants; Body Water; Brain; Brain Edema; Brain Injuries; Cognition; Cognition Disord | 2000 |
Early antithrombotic prophylaxis with low molecular weight heparin in neurosurgery.
Topics: Adult; Aged; Aged, 80 and over; Brain Injuries; Brain Neoplasms; Cerebrospinal Fluid Shunts; Contrai | 2003 |
Diagnosis of carotid arterial injury in major trauma using a modification of Memphis criteria.
Topics: Adult; Anticoagulants; Brain Injuries; Carotid Artery Injuries; Dalteparin; Humans; Intensive Care U | 2010 |