dalteparin has been researched along with Abortion, Recurrent in 65 studies
Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess whether treatment with enoxaparin and low-dose aspirin, along with intensive pregnancy surveillance, reduces rate of pregnancy loss compared with intensive pregnancy surveillance alone in women with history of 2 or more consecutive previous pregnancy losses, a parallel group, multicenter, randomized controlled trial was performed in the United Kingdom and New Zealand." | 9.14 | SPIN (Scottish Pregnancy Intervention) study: a multicenter, randomized controlled trial of low-molecular-weight heparin and low-dose aspirin in women with recurrent miscarriage. ( Clark, P; Crichton, L; Greaves, M; Greer, IA; Langhorne, P; Thomson, A; Walker, ID; Whyte, S, 2010) |
| "To evaluate the efficacy and safety of anticoagulant agents, such as aspirin and heparin, in women with a history of at least two unexplained miscarriages with or without inherited thrombophilia." | 8.90 | Aspirin and/or heparin for women with unexplained recurrent miscarriage with or without inherited thrombophilia. ( de Jong, PG; Di Nisio, M; Goddijn, M; Kaandorp, S; Middeldorp, S, 2014) |
| "Dysfibrinogenemia is caused by a variety of structural abnormalities in the fibrinogen molecule, which results in a tendency for bleeding and thrombosis as well as obstetric complications." | 7.75 | Treatment of patients with dysfibrinogenemia and a history of abortions during pregnancy. ( Galanakis, D; Miesbach, W; Scharrer, I, 2009) |
| "The aim of this retrospective, observational study was to determine the impact of low-dose enoxaparin (20 mg) in conjunction with low-dose aspirin on the pregnancy outcome of women with antiphospholipid syndrome and recurrent miscarriage." | 7.75 | Treatment of recurrent miscarriage and antiphospholipid syndrome with low-dose enoxaparin and aspirin. ( Li, TC; Makris, M; Metwally, M; Mo, D; Saravelos, S, 2009) |
| "Dalteparin sodium injection in patients with an immunologic component to RPL resulted in an increase in compliance without any adverse early pregnancy outcomes." | 7.70 | Dalteparin sodium injection treatment in patients with immunologic recurrent pregnancy loss. ( Trott, AM; Trott, EA, 2000) |
| " No adverse maternal-fetal side effects were reported on enoxaparin alone or enoxaparin-metformin." | 6.74 | Enoxaparin-metformin and enoxaparin alone may safely reduce pregnancy loss. ( Glueck, CJ; Goldenberg, N; Khan, N; Ramidi, G; Wang, P, 2009) |
| "Screening results for thrombophilia and antithrombotic treatment with enoxaparin, aspirin, or both and pregnancy outcomes." | 5.27 | The Prevalence of Thrombophilia in Women With Recurrent Fetal Loss and Outcome of Anticoagulation Therapy for the Prevention of Miscarriages. ( Elias, A; Elias, M; Nahas, R; Saliba, W, 2018) |
| " The study group included 150 patients receiving LMWH (Tinzaparin sodium 4500 IU) subcutaneous daily injection with 500 µg folic acid once daily orally started once positive pregnancy test till the 20th week of gestation." | 5.24 | Low-Molecular-Weight Heparin for the Treatment of Unexplained Recurrent Miscarriage With Negative Antiphospholipid Antibodies: A Randomized Controlled Trial. ( Abbas, AM; Anan, MA; Fathalla, MM; Salman, SA; Shaaban, OM; Zahran, KM, 2017) |
| "To determine whether low molecular weight heparin (LMWH) plus low-dose aspirin (LDA) is comparable in efficacy and safety to unfractionated heparin (UFH) plus LDA in the management of pregnant women with a history of recurrent spontaneous abortion secondary to antiphospholipid syndrome (APS)." | 5.15 | Enoxaparin versus unfractionated heparin in the management of recurrent abortion secondary to antiphospholipid syndrome. ( Abdou, AM; Fouda, IM; Fouda, UM; Ramadan, DI; Sayed, AM; Zaki, MM, 2011) |
| " We then randomly assigned them to receive daily 80 mg of aspirin plus open-label subcutaneous nadroparin (at a dose of 2850 IU, starting as soon as a viable pregnancy was demonstrated), 80 mg of aspirin alone, or placebo." | 5.14 | Aspirin plus heparin or aspirin alone in women with recurrent miscarriage. ( Büller, HR; Folkeringa, N; Goddijn, M; Hamulyák, K; Hutten, BA; Kaandorp, SP; Middeldorp, S; Mol, BW; Nahuis, M; Papatsonis, DN; van der Post, JA; van der Veen, F; Verhoeve, HR, 2010) |
| "To assess whether treatment with enoxaparin and low-dose aspirin, along with intensive pregnancy surveillance, reduces rate of pregnancy loss compared with intensive pregnancy surveillance alone in women with history of 2 or more consecutive previous pregnancy losses, a parallel group, multicenter, randomized controlled trial was performed in the United Kingdom and New Zealand." | 5.14 | SPIN (Scottish Pregnancy Intervention) study: a multicenter, randomized controlled trial of low-molecular-weight heparin and low-dose aspirin in women with recurrent miscarriage. ( Clark, P; Crichton, L; Greaves, M; Greer, IA; Langhorne, P; Thomson, A; Walker, ID; Whyte, S, 2010) |
| "To compare the use of enoxaparin alone with combination therapy of prednisone, aspirin and progesterone in the treatment of women with idiopathic recurrent miscarriage (IRM) in terms of live births and pregnancy outcome." | 5.13 | Treatment options and pregnancy outcome in women with idiopathic recurrent miscarriage: a randomized placebo-controlled study. ( El-Refaiey, AA; El-Tatongy, M; Fawzy, M; Mosbah, A; Shokeir, T; Warda, O, 2008) |
| "To compare the effect of aspirin and enoxaparin on live births in women with unexplained recurrent miscarriages, as well as secondary outcomes including birth weight, uterine and umbilical blood flows, and congenital malformations." | 5.12 | A randomized study of thromboprophylaxis in women with unexplained consecutive recurrent miscarriages. ( Brenner, B; Carp, H; Dolitzky, M; Inbal, A; Segal, Y; Weiss, A, 2006) |
| "To evaluate the efficacy and safety of anticoagulant agents, such as aspirin and heparin, in women with a history of at least two unexplained miscarriages with or without inherited thrombophilia." | 4.90 | Aspirin and/or heparin for women with unexplained recurrent miscarriage with or without inherited thrombophilia. ( de Jong, PG; Di Nisio, M; Goddijn, M; Kaandorp, S; Middeldorp, S, 2014) |
| "Dysfibrinogenemia is caused by a variety of structural abnormalities in the fibrinogen molecule, which results in a tendency for bleeding and thrombosis as well as obstetric complications." | 3.75 | Treatment of patients with dysfibrinogenemia and a history of abortions during pregnancy. ( Galanakis, D; Miesbach, W; Scharrer, I, 2009) |
| "The aim of this retrospective, observational study was to determine the impact of low-dose enoxaparin (20 mg) in conjunction with low-dose aspirin on the pregnancy outcome of women with antiphospholipid syndrome and recurrent miscarriage." | 3.75 | Treatment of recurrent miscarriage and antiphospholipid syndrome with low-dose enoxaparin and aspirin. ( Li, TC; Makris, M; Metwally, M; Mo, D; Saravelos, S, 2009) |
| " Aspirin, 75 mg daily was given in addition to enoxaparin to women with antiphospholipid syndrome." | 3.70 | Gestational outcome in thrombophilic women with recurrent pregnancy loss treated by enoxaparin. ( Blumenfeld, Z; Brenner, B; Hoffman, R; Weiner, Z; Younis, JS, 2000) |
| "Dalteparin sodium injection in patients with an immunologic component to RPL resulted in an increase in compliance without any adverse early pregnancy outcomes." | 3.70 | Dalteparin sodium injection treatment in patients with immunologic recurrent pregnancy loss. ( Trott, AM; Trott, EA, 2000) |
| "Aspirin and heparin have been shown to have potentially beneficial effects on trophoblast implantation." | 2.79 | Low dose aspirin and low-molecular-weight heparin in the treatment of pregnant Libyan women with recurrent miscarriage. ( Adam, I; Ashur, BM; Elbareg, AM; Elmahashi, MO; Essadi, FM, 2014) |
| "In more than half of all recurrent miscarriage the cause still remains uncertain." | 2.76 | Thromboprophylaxis for recurrent miscarriage in women with or without thrombophilia. HABENOX: a randomised multicentre trial. ( Bloemenkamp, KW; Helmerhorst, FM; Kaaja, RJ; Lampinen, K; Morin-Papunen, L; Ulander, VM; Visser, J, 2011) |
| " No adverse maternal-fetal side effects were reported on enoxaparin alone or enoxaparin-metformin." | 2.74 | Enoxaparin-metformin and enoxaparin alone may safely reduce pregnancy loss. ( Glueck, CJ; Goldenberg, N; Khan, N; Ramidi, G; Wang, P, 2009) |
| "In women with a history of recurrent miscarriage, the risk of miscarriage in a subsequent pregnancy is about 30% to 40%." | 2.74 | Use of heparin in women with early and late miscarriages with and without thrombophilia. ( Baumgarten, S; Dörner, T; Kadecki, O; Kiesewetter, H; Monien, S; Salama, A, 2009) |
| "Compared with control intervention for recurrent miscarriage, enoxaparin treatment has no substantial influence on live births (RR = 1." | 2.61 | Enoxaparin (or plus aspirin) for the prevention of recurrent miscarriage: A meta-analysis of randomized controlled studies. ( Chen, Y; Cheng, X; Li, N; Lin, T; Sheng, X, 2019) |
| "Women with thrombophilia have an increased risk of pregnancy loss and possibly other serious obstetric complications, although definition of the magnitude of risk will require prospective longitudinal studies." | 2.42 | Thrombophilia and pregnancy complications. ( Kujovich, JL, 2004) |
| "TNFi combined with IVIG and heparin therapy improves the live birth rate but does not elevate the adverse events compared to IVIG and heparin therapy in RSA patients." | 1.72 | Tumour necrosis factor inhibitor combined with intravenous immunoglobulin and heparin for treatment of recurrent spontaneous abortion: A two-centre, retrospective, cohort study. ( Chen, J; Chen, X; Jiang, Y; Wu, H; You, Q; Zhang, N; Zou, Q, 2022) |
| "Thrombophilia was present in 38 (33." | 1.46 | Outcomes of threatened abortions after anticoagulation treatment to prevent recurrent pregnancy loss. ( Amsalem, H; Kalish, Y; Kleinstern, G; Rottenstreich, A, 2017) |
| " The lowest dose-response curve was at 36 weeks' gestation." | 1.32 | A longitudinal study of maternal dose response to low molecular weight heparin in pregnancy. ( Back, DJ; Cowan, C; Farquharson, RG; Quenby, SM; Sephton, V; Toh, CH; Topping, J, 2003) |
| " The objectives of this investigation were to characterize the safety and pharmacokinetic behavior of a low-molecular weight heparin (reviparin) administered throughout pregnancy." | 1.31 | Pharmacokinetic profile of a low-molecular weight heparin (reviparin) in pregnant patients. A prospective cohort study. ( Crowther, MA; Crowther, R; Ginsberg, J; Johnston, M; Julian, J; Laskin, C; Spitzer, K, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (1.54) | 18.2507 |
| 2000's | 30 (46.15) | 29.6817 |
| 2010's | 30 (46.15) | 24.3611 |
| 2020's | 4 (6.15) | 2.80 |
| Authors | Studies |
|---|---|
| Bai, W | 1 |
| Zhang, X | 2 |
| Sun, S | 1 |
| Wang, Q | 1 |
| Li, C | 1 |
| Zhao, A | 1 |
| de Jong, PG | 2 |
| Kaandorp, S | 1 |
| Di Nisio, M | 1 |
| Goddijn, M | 3 |
| Middeldorp, S | 3 |
| Kaandorp, SP | 1 |
| van der Post, JA | 1 |
| Hutten, BA | 2 |
| Verhoeve, HR | 2 |
| Hamulyák, K | 1 |
| Mol, BW | 2 |
| Folkeringa, N | 1 |
| Nahuis, M | 1 |
| Papatsonis, DN | 1 |
| Büller, HR | 1 |
| van der Veen, F | 1 |
| Greer, IA | 2 |
| Lewandowski, K | 1 |
| Balcerzak, A | 1 |
| Kubiaczyk-Paluch, B | 1 |
| Breborowicz, GH | 1 |
| Alalaf, S | 1 |
| Jiang, Y | 2 |
| Zou, Q | 2 |
| Zhang, N | 2 |
| Chen, J | 2 |
| Chen, X | 2 |
| You, Q | 2 |
| Wu, H | 2 |
| Serrano, F | 1 |
| Bisdorff-Bresson, A | 1 |
| Sroussi, J | 1 |
| Aymard, A | 1 |
| Wassef, M | 1 |
| Civelli, V | 1 |
| Boujlel, S | 1 |
| Houdart, E | 1 |
| Drouet, L | 1 |
| Jerzak, M | 1 |
| Szafarowska, M | 1 |
| Kniotek, M | 1 |
| Gorski, A | 1 |
| Rottenstreich, A | 1 |
| Amsalem, H | 1 |
| Kleinstern, G | 1 |
| Kalish, Y | 1 |
| Lin, T | 1 |
| Chen, Y | 1 |
| Cheng, X | 1 |
| Li, N | 1 |
| Sheng, X | 1 |
| Liu, Y | 1 |
| Shan, N | 1 |
| Yuan, Y | 1 |
| Tan, B | 1 |
| Che, P | 1 |
| Qi, H | 1 |
| Solt, I | 1 |
| Ben David, C | 1 |
| Carp, H | 4 |
| Bouvier, S | 1 |
| Cochery-Nouvellon, E | 1 |
| Lavigne-Lissalde, G | 1 |
| Mercier, E | 1 |
| Marchetti, T | 1 |
| Balducchi, JP | 2 |
| Marès, P | 4 |
| Gris, JC | 4 |
| Elmahashi, MO | 1 |
| Elbareg, AM | 1 |
| Essadi, FM | 1 |
| Ashur, BM | 1 |
| Adam, I | 1 |
| Pasquier, E | 1 |
| de Saint Martin, L | 1 |
| Bohec, C | 1 |
| Chauleur, C | 1 |
| Bretelle, F | 1 |
| Marhic, G | 1 |
| Le Gal, G | 1 |
| Debarge, V | 1 |
| Lecomte, F | 1 |
| Denoual-Ziad, C | 1 |
| Lejeune-Saada, V | 1 |
| Douvier, S | 1 |
| Heisert, M | 1 |
| Mottier, D | 1 |
| Rodger, MA | 1 |
| Quenby, S | 1 |
| Bloemenkamp, KW | 2 |
| Braams-Lisman, BA | 1 |
| de Bruin, JP | 1 |
| Coomarasamy, A | 1 |
| David, M | 1 |
| DeSancho, MT | 1 |
| van der Heijden, OW | 1 |
| Hoek, A | 1 |
| Jochmans, K | 1 |
| Koks, CA | 1 |
| Kuchenbecker, WK | 1 |
| Torrance, HL | 1 |
| Scheepers, HC | 1 |
| Stephenson, MD | 1 |
| Visser, J | 2 |
| de Vries, JI | 1 |
| Ismail, AM | 1 |
| Hamed, AH | 1 |
| Saso, S | 1 |
| Abu-Elhasan, AM | 1 |
| Abu-Elghar, MM | 1 |
| Abdelmeged, AN | 1 |
| Nahas, R | 1 |
| Saliba, W | 1 |
| Elias, A | 1 |
| Elias, M | 1 |
| Alijotas-Reig, J | 1 |
| Casellas-Caro, M | 1 |
| Ferrer-Oliveras, R | 1 |
| Llurba-Olive, E | 1 |
| Hermosilla, E | 1 |
| Vilardell-Tarres, M | 1 |
| Cabero-Roura, L | 1 |
| Ramidi, G | 1 |
| Khan, N | 2 |
| Glueck, CJ | 3 |
| Wang, P | 3 |
| Goldenberg, N | 2 |
| Tsakok, AD | 1 |
| Miesbach, W | 1 |
| Galanakis, D | 1 |
| Scharrer, I | 1 |
| Mo, D | 1 |
| Saravelos, S | 1 |
| Metwally, M | 1 |
| Makris, M | 1 |
| Li, TC | 1 |
| Clark, P | 1 |
| Walker, ID | 1 |
| Langhorne, P | 1 |
| Crichton, L | 1 |
| Thomson, A | 1 |
| Greaves, M | 1 |
| Whyte, S | 1 |
| Junovich, G | 1 |
| Dubinsky, V | 1 |
| Gentile, T | 1 |
| Sarto, A | 2 |
| Pasqualini, S | 1 |
| Gutiérrez, G | 1 |
| Pranikoff, J | 1 |
| Riaz, K | 1 |
| Chavan, K | 1 |
| Raj, P | 1 |
| Umar, M | 1 |
| Ulander, VM | 1 |
| Helmerhorst, FM | 1 |
| Lampinen, K | 1 |
| Morin-Papunen, L | 1 |
| Kaaja, RJ | 1 |
| Fouda, UM | 2 |
| Sayed, AM | 2 |
| Ramadan, DI | 2 |
| Fouda, IM | 2 |
| Sucak, A | 1 |
| Acar, K | 1 |
| Celen, S | 1 |
| Danisman, N | 1 |
| Sucak, GT | 1 |
| Abdou, AM | 1 |
| Zaki, MM | 1 |
| Misra, D | 1 |
| Aledort, L | 1 |
| Bashiri, A | 1 |
| Ratzon, R | 1 |
| Amar, S | 1 |
| Serjienko, R | 1 |
| Mazor, M | 1 |
| Shoham-Vardi, I | 1 |
| D'Ippolito, S | 1 |
| Di Nicuolo, F | 1 |
| Marana, R | 1 |
| Castellani, R | 1 |
| Stinson, J | 1 |
| Tersigni, C | 1 |
| Scambia, G | 1 |
| Di Simone, N | 1 |
| Dolitzky, M | 2 |
| Inbal, A | 2 |
| Kujovich, JL | 1 |
| Sieve, L | 1 |
| Lindqvist, PG | 2 |
| Merlo, J | 2 |
| Brenner, B | 7 |
| Hoffman, R | 2 |
| Dulitsky, M | 1 |
| Younis, J | 1 |
| Bar, J | 1 |
| Ellis, M | 1 |
| Yarom, I | 1 |
| Yohai, D | 1 |
| Samueloff, A | 1 |
| Sarig, G | 1 |
| Blumenfeld, Z | 2 |
| Leiba, R | 1 |
| Lanir, N | 2 |
| Segal, Y | 1 |
| Weiss, A | 1 |
| Fawzy, M | 1 |
| Shokeir, T | 1 |
| El-Tatongy, M | 1 |
| Warda, O | 1 |
| El-Refaiey, AA | 1 |
| Mosbah, A | 1 |
| Bick, RL | 1 |
| Grandone, E | 1 |
| De Stefano, V | 1 |
| Rossi, E | 1 |
| Cappucci, F | 1 |
| Colaizzo, D | 1 |
| Margaglione, M | 1 |
| Neveu, S | 1 |
| Tailland, ML | 1 |
| Courtieu, C | 1 |
| Schved, JF | 1 |
| Younis, JS | 2 |
| Ohel, G | 1 |
| Haddad, S | 1 |
| Ben-Ami, M | 1 |
| Weiner, Z | 1 |
| Rocha, M | 1 |
| Geller, M | 1 |
| Capmany, C | 1 |
| Martínez, M | 1 |
| Quintans, C | 1 |
| Donaldson, M | 1 |
| Pasqualini, RS | 1 |
| Quéré, I | 1 |
| Hoffet, M | 1 |
| Crowther, MA | 1 |
| Spitzer, K | 1 |
| Julian, J | 1 |
| Ginsberg, J | 1 |
| Johnston, M | 1 |
| Crowther, R | 1 |
| Laskin, C | 1 |
| Abdulghani, S | 1 |
| Moretti, F | 1 |
| Gruslin, A | 1 |
| Grynspan, D | 1 |
| Schleussner, E | 1 |
| Kamin, G | 1 |
| Seliger, G | 1 |
| Rogenhofer, N | 1 |
| Ebner, S | 1 |
| Toth, B | 1 |
| Schenk, M | 1 |
| Henes, M | 1 |
| Bohlmann, MK | 1 |
| Fischer, T | 1 |
| Brosteanu, O | 1 |
| Bauersachs, R | 1 |
| Petroff, D | 1 |
| Luna, RL | 1 |
| Vasconcelos, AG | 1 |
| Nunes, AK | 1 |
| de Oliveira, WH | 1 |
| Barbosa, KP | 1 |
| Peixoto, CA | 1 |
| Monien, S | 1 |
| Kadecki, O | 1 |
| Baumgarten, S | 1 |
| Salama, A | 1 |
| Dörner, T | 1 |
| Kiesewetter, H | 1 |
| Eldor, A | 1 |
| Sephton, V | 1 |
| Farquharson, RG | 1 |
| Topping, J | 1 |
| Quenby, SM | 1 |
| Cowan, C | 1 |
| Back, DJ | 1 |
| Toh, CH | 1 |
| Trott, EA | 1 |
| Trott, AM | 1 |
| Khalifeh, A | 1 |
| Grantham, J | 1 |
| Byrne, J | 1 |
| Murphy, K | 1 |
| McAuliffe, F | 1 |
| Byrne, B | 1 |
| Shaaban, OM | 1 |
| Abbas, AM | 1 |
| Zahran, KM | 1 |
| Fathalla, MM | 1 |
| Anan, MA | 1 |
| Salman, SA | 1 |
| Dendrinos, S | 1 |
| Kalogirou, I | 1 |
| Makrakis, E | 1 |
| Theodoridis, T | 1 |
| Mahmound, EA | 1 |
| Christopoulou-Cokkinou, V | 1 |
| Creatsas, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Hydroxychloroquine in Unexplained Recurrent Pregnancy Loss ,Double Blinded Randomized Controlled Trial .[NCT05237843] | Phase 1 | 70 participants (Anticipated) | Interventional | 2022-03-01 | Not yet recruiting | ||
| Effects of Aspirin and Intrauterine Balloon on the Post-operative Uterine Endometrial Repair and Reproductive Prognosis in Patients With Severe Intrauterine Adhesion: a Prospective Cohort Study[NCT02744716] | 114 participants (Actual) | Interventional | 2011-05-31 | Completed | |||
| Low-molecular-weight Heparin to Prevent Recurrent VTE in Pregnancy: a Randomized Controlled Trial of Two Doses[NCT01828697] | Phase 4 | 1,110 participants (Actual) | Interventional | 2013-04-24 | Completed | ||
| Low Dose Aspirin and Low-molecular-weight Heparin in the Treatment of Pregnant Libyan Women With Recurrent Miscarriage[NCT01917799] | Phase 4 | 150 participants (Anticipated) | Interventional | 2009-01-31 | Recruiting | ||
| Essai thérapeutique randomisé Multicentrique en Double Insu, Comparant l'énoxaparine 40mg Versus Placebo, en Une Injection Sous-cutanée Quotidienne, Dans Les Fausses Couches spontanées récurrentes inexpliquées[NCT00740545] | Phase 3 | 258 participants (Actual) | Interventional | 2007-04-30 | Terminated (stopped due to Stopped for futility) | ||
| A Randomized Clinical Trial of Using Preconceptional Enoxaparin AND Low Dose Aspirin 81mg in Patient With Antiphospholipid Syndrome(APS)[NCT01661439] | 316 participants (Anticipated) | Observational | 2012-03-31 | Recruiting | |||
| Low-molecular-weight Heparin Versus Unfractionated Heparin in Pregnant Women With History of Recurrent Abortion Secondary to Antiphospholipid Syndrome. A Randomized Controlled Trial[NCT01051778] | Phase 2 | 60 participants (Actual) | Interventional | 2006-06-30 | Completed | ||
| Phase III Study Analyzing the Effectiveness of Dalteparin Therapy as Intervention in Recurrent Pregnancy Loss[NCT00400387] | Phase 3 | 449 participants (Actual) | Interventional | 2006-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Live birth occurs when a fetus (> 24 weeks ) , exits the maternal body and subsequently shows signs of life, such as voluntary movement, heartbeat, or pulsation of the umbilical cord. (NCT01051778)
Timeframe: pregnancy > 24weeks gestation
| Intervention | Percentage of pregnancies (Number) |
|---|---|
| Enoxaparin 40 mg /Day Plus Low Dose Aspirin | 24 |
| Heparin Calcium 5,000 U Twice Daily Plus Low Dose Aspirin | 20 |
6 reviews available for dalteparin and Abortion, Recurrent
| Article | Year |
|---|---|
Aspirin and/or heparin for women with unexplained recurrent miscarriage with or without inherited thrombophilia.
Topics: Abortion, Habitual; Anticoagulants; Antiphospholipid Syndrome; Aspirin; Enoxaparin; Female; Heparin, | 2014 |
Enoxaparin (or plus aspirin) for the prevention of recurrent miscarriage: A meta-analysis of randomized controlled studies.
Topics: Abortion, Habitual; Anticoagulants; Aspirin; Enoxaparin; Female; Humans; Live Birth; Pre-Eclampsia; | 2019 |
The efficacy of enoxaparin for recurrent abortion: a meta-analysis of randomized controlled studies.
Topics: Abortion, Habitual; Enoxaparin; Female; Humans; Infant, Newborn; Live Birth; Pre-Eclampsia; Pregnanc | 2021 |
Thrombophilia and pregnancy complications.
Topics: Abortion, Habitual; Enoxaparin; Factor V; Female; Fetal Growth Retardation; Fibrinolytic Agents; Hum | 2004 |
Antiphospholipid syndrome in pregnancy.
Topics: Abortion, Habitual; Antibodies, Antiphospholipid; Anticoagulants; Antiphospholipid Syndrome; Aspirin | 2008 |
The use of low-molecular-weight heparin for the management of venous thromboembolism in pregnancy.
Topics: Abortion, Habitual; Analgesia, Epidural; Anticoagulants; Bone Density; Dalteparin; Female; Guideline | 2002 |
26 trials available for dalteparin and Abortion, Recurrent
| Article | Year |
|---|---|
Aspirin plus heparin or aspirin alone in women with recurrent miscarriage.
Topics: Abortion, Habitual; Adult; Anticoagulants; Aspirin; Contusions; Drug Therapy, Combination; Female; H | 2010 |
Aspirin plus heparin or aspirin alone in women with recurrent miscarriage.
Topics: Abortion, Habitual; Adult; Anticoagulants; Aspirin; Contusions; Drug Therapy, Combination; Female; H | 2010 |
Aspirin plus heparin or aspirin alone in women with recurrent miscarriage.
Topics: Abortion, Habitual; Adult; Anticoagulants; Aspirin; Contusions; Drug Therapy, Combination; Female; H | 2010 |
Aspirin plus heparin or aspirin alone in women with recurrent miscarriage.
Topics: Abortion, Habitual; Adult; Anticoagulants; Aspirin; Contusions; Drug Therapy, Combination; Female; H | 2010 |
Bemiparin versus low dose aspirin for management of recurrent early pregnancy losses due to antiphospholipd antibody syndrome.
Topics: Abortion, Habitual; Adult; Antiphospholipid Syndrome; Aspirin; Embryo Loss; Female; Heparin, Low-Mol | 2012 |
Low dose aspirin and low-molecular-weight heparin in the treatment of pregnant Libyan women with recurrent miscarriage.
Topics: Abortion, Habitual; Adult; Aspirin; Birth Weight; Embryo Implantation; Enoxaparin; Female; Fibrinoly | 2014 |
Enoxaparin for prevention of unexplained recurrent miscarriage: a multicenter randomized double-blind placebo-controlled trial.
Topics: Abortion, Habitual; Adult; Anticoagulants; Double-Blind Method; Enoxaparin; Female; Follow-Up Studie | 2015 |
ALIFE2 study: low-molecular-weight heparin for women with recurrent miscarriage and inherited thrombophilia--study protocol for a randomized controlled trial.
Topics: Abortion, Habitual; Adolescent; Adult; Anticoagulants; Clinical Protocols; Drug Administration Sched | 2015 |
Randomized controlled study of pre-conception thromboprophylaxis among patients with recurrent spontaneous abortion related to antiphospholipid syndrome.
Topics: Abortion, Habitual; Adult; Antiphospholipid Syndrome; Aspirin; Drug Therapy, Combination; Egypt; Eno | 2016 |
The Prevalence of Thrombophilia in Women With Recurrent Fetal Loss and Outcome of Anticoagulation Therapy for the Prevention of Miscarriages.
Topics: Abortion, Habitual; Adolescent; Adult; Anticoagulants; Aspirin; Enoxaparin; Female; Humans; Middle A | 2018 |
Enoxaparin-metformin and enoxaparin alone may safely reduce pregnancy loss.
Topics: Abortion, Habitual; Abortion, Spontaneous; Adult; Anticoagulants; Blood Coagulation Disorders; Dose- | 2009 |
SPIN (Scottish Pregnancy Intervention) study: a multicenter, randomized controlled trial of low-molecular-weight heparin and low-dose aspirin in women with recurrent miscarriage.
Topics: Abortion, Habitual; Adult; Anticoagulants; Aspirin; Enoxaparin; Female; Humans; Infant, Newborn; Pla | 2010 |
High factor XI, recurrent pregnancy loss, enoxaparin.
Topics: Abortion, Habitual; Anticoagulants; Cohort Studies; Embryo Loss; Enoxaparin; Factor XI; Female; Homo | 2010 |
Thromboprophylaxis for recurrent miscarriage in women with or without thrombophilia. HABENOX: a randomised multicentre trial.
Topics: Abortion, Habitual; Adolescent; Adult; Aspirin; Double-Blind Method; Drug Therapy, Combination; Earl | 2011 |
Efficacy and safety of two doses of low molecular weight heparin (enoxaparin) in pregnant women with a history of recurrent abortion secondary to antiphospholipid syndrome.
Topics: Abortion, Habitual; Adult; Anticoagulants; Antiphospholipid Syndrome; Enoxaparin; Female; Humans; In | 2010 |
Outcome of pregnancies in women with thrombophilic disorders.
Topics: Abortion, Habitual; Adult; Anticoagulants; Enoxaparin; Female; Fetal Death; Humans; Live Birth; Preg | 2010 |
Enoxaparin versus unfractionated heparin in the management of recurrent abortion secondary to antiphospholipid syndrome.
Topics: Abortion, Habitual; Adult; Antibodies, Antiphospholipid; Anticoagulants; Antiphospholipid Syndrome; | 2011 |
Thromboprophylaxis improves the live birth rate in women with consecutive recurrent miscarriages and hereditary thrombophilia.
Topics: Abortion, Habitual; Adult; Birth Rate; Enoxaparin; Family Health; Female; Fibrinolytic Agents; Human | 2003 |
Pregnancy loss, polycystic ovary syndrome, thrombophilia, hypofibrinolysis, enoxaparin, metformin.
Topics: Abortion, Habitual; Abortion, Spontaneous; Adult; Blood Coagulation Disorders; Case-Control Studies; | 2004 |
Efficacy and safety of two doses of enoxaparin in women with thrombophilia and recurrent pregnancy loss: the LIVE-ENOX study.
Topics: Abortion, Habitual; Dose-Response Relationship, Drug; Drug Hypersensitivity; Enoxaparin; Female; Hem | 2005 |
Modulation of systemic hemostatic parameters by enoxaparin during gestation in women with thrombophilia and pregnancy loss.
Topics: Abortion, Habitual; Adult; Anticoagulants; Enoxaparin; Female; Fibrin Fibrinogen Degradation Product | 2005 |
A randomized study of thromboprophylaxis in women with unexplained consecutive recurrent miscarriages.
Topics: Abortion, Habitual; Abortion, Induced; Adult; Anticoagulants; Aspirin; Birth Rate; Birth Weight; Eno | 2006 |
Treatment options and pregnancy outcome in women with idiopathic recurrent miscarriage: a randomized placebo-controlled study.
Topics: Abortion, Habitual; Adult; Anti-Inflammatory Agents; Aspirin; Drug Therapy, Combination; Enoxaparin; | 2008 |
Use of a low-molecular weight heparin (enoxaparin) or of a phenformin-like substance (moroxydine chloride) in primary early recurrent aborters with an impaired fibrinolytic capacity.
Topics: Abortion, Habitual; Adult; Biguanides; Double-Blind Method; Enoxaparin; Female; Fibrinolysis; Humans | 1995 |
Enoxaparin sodium improves pregnancy outcome in aspirin-resistant antiphospholipid/antiprotein antibody syndromes.
Topics: Abortion, Habitual; Anticoagulants; Antiphospholipid Syndrome; Aspirin; Drug Resistance; Enoxaparin; | 2002 |
Low-molecular-weight heparin for women with unexplained recurrent pregnancy loss: a multicenter trial with a minimization randomization scheme.
Topics: Abortion, Habitual; Anticoagulants; Dalteparin; Female; Heparin, Low-Molecular-Weight; Humans; Injec | 2015 |
Use of heparin in women with early and late miscarriages with and without thrombophilia.
Topics: Abortion, Habitual; Adult; Age Factors; Aspirin; Biomarkers; Case-Control Studies; Dalteparin; Drug | 2009 |
Low-Molecular-Weight Heparin for the Treatment of Unexplained Recurrent Miscarriage With Negative Antiphospholipid Antibodies: A Randomized Controlled Trial.
Topics: Abortion, Habitual; Adult; Antibodies, Antiphospholipid; Female; Folic Acid; Heparin, Low-Molecular- | 2017 |
Safety and effectiveness of tinzaparin sodium in the management of recurrent pregnancy loss.
Topics: Abortion, Habitual; Adult; Aspirin; Female; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Huma | 2007 |
33 other studies available for dalteparin and Abortion, Recurrent
| Article | Year |
|---|---|
Effect of low-molecular-weight heparins on anti-Xa peak levels and adverse reactions in Chinese patients with recurrent spontaneous abortion: a single-center, observational study.
Topics: Abortion, Habitual; Adult; Anticoagulants; Asian People; Blood Coagulation; China; Dalteparin; Drug | 2021 |
Antithrombotic therapy for recurrent miscarriage?
Topics: Abortion, Habitual; Anticoagulants; Aspirin; Drug Therapy, Combination; Female; Humans; Nadroparin; | 2010 |
[Successful pregnancy outcome in the woman with thrombophilia and multiple miscarriages].
Topics: Abortion, Habitual; Adult; Anticoagulants; Aspirin; Cesarean Section; Factor V; Female; Heterozygote | 2003 |
Tumour necrosis factor inhibitor combined with intravenous immunoglobulin and heparin for treatment of recurrent spontaneous abortion: A two-centre, retrospective, cohort study.
Topics: Abortion, Habitual; Anticoagulants; Cohort Studies; Enoxaparin; Female; Heparin; Humans; Immunoglobu | 2022 |
Tumour necrosis factor inhibitor combined with intravenous immunoglobulin and heparin for treatment of recurrent spontaneous abortion: A two-centre, retrospective, cohort study.
Topics: Abortion, Habitual; Anticoagulants; Cohort Studies; Enoxaparin; Female; Heparin; Humans; Immunoglobu | 2022 |
Tumour necrosis factor inhibitor combined with intravenous immunoglobulin and heparin for treatment of recurrent spontaneous abortion: A two-centre, retrospective, cohort study.
Topics: Abortion, Habitual; Anticoagulants; Cohort Studies; Enoxaparin; Female; Heparin; Humans; Immunoglobu | 2022 |
Tumour necrosis factor inhibitor combined with intravenous immunoglobulin and heparin for treatment of recurrent spontaneous abortion: A two-centre, retrospective, cohort study.
Topics: Abortion, Habitual; Anticoagulants; Cohort Studies; Enoxaparin; Female; Heparin; Humans; Immunoglobu | 2022 |
Giant intrahepatic venous malformation with localized intravascular coagulopathy. Follow-up and treatment during pregnancy.
Topics: Abortion, Habitual; Adult; Anticoagulants; Blood Coagulation Disorders; Cesarean Section; Enoxaparin | 2020 |
Successful pregnancy after Intralipid addition to sildenafil and enoxaparin in woman with history of recurrent pregnancy loss (RPL).
Topics: Abortion, Habitual; Adult; Enoxaparin; Female; Humans; Pregnancy; Pregnancy Outcome; Sildenafil Citr | 2016 |
Outcomes of threatened abortions after anticoagulation treatment to prevent recurrent pregnancy loss.
Topics: Abortion, Habitual; Abortion, Threatened; Adult; Anticoagulants; Enoxaparin; Female; Humans; Live Bi | 2017 |
Enoxaparin (or plus aspirin) for the prevention of recurrent miscarriage: a meta-analysis of randomized controlled studies.
Topics: Abortion, Habitual; Anticoagulants; Aspirin; Enoxaparin; Female; Humans; Pregnancy; Prospective Stud | 2019 |
Comparative incidence of pregnancy outcomes in treated obstetric antiphospholipid syndrome: the NOH-APS observational study.
Topics: Abortion, Habitual; Abortion, Spontaneous; Adolescent; Adult; Antibodies, Anticardiolipin; Antibodie | 2014 |
Recurrent pregnancy loss: drop the heparin needles….
Topics: Abortion, Habitual; Enoxaparin; Female; Humans; Pregnancy; Pregnancy Complications | 2015 |
Are anti-beta-glycoprotein-I antibodies markers for recurrent pregnancy loss in lupus anticoagulant/anticardiolipin seronegative women?
Topics: Abortion, Habitual; Adult; Antibodies, Anticardiolipin; Antibodies, Antiphospholipid; Anticoagulants | 2008 |
On some treatment analyses.
Topics: Abortion, Habitual; Bias; Data Interpretation, Statistical; Enoxaparin; Fibrinolytic Agents; Humans; | 2009 |
Treatment of patients with dysfibrinogenemia and a history of abortions during pregnancy.
Topics: Abortion, Habitual; Abruptio Placentae; Adult; Afibrinogenemia; Enoxaparin; Female; Fibrinogen; Fibr | 2009 |
Treatment of recurrent miscarriage and antiphospholipid syndrome with low-dose enoxaparin and aspirin.
Topics: Abortion, Habitual; Adult; Anticoagulants; Antiphospholipid Syndrome; Aspirin; Dose-Response Relatio | 2009 |
Comparative immunological effect of anticoagulant and antioxidant therapy in the prevention of abortion in mice.
Topics: Abortion, Habitual; Abortion, Induced; Animals; Anticoagulants; Antioxidants; Enoxaparin; Female; Hu | 2011 |
Recurrent miscarriages: caution regarding development of clinical trials using low molecular weight heparin and pregnancy.
Topics: Abortion, Habitual; Adult; Anticoagulants; Clinical Trials as Topic; Dose-Response Relationship, Dru | 2011 |
Two vs. three or more primary recurrent pregnancy losses--are there any differences in epidemiologic characteristics and index pregnancy outcome?
Topics: Abortion, Habitual; Abortion, Spontaneous; Anticoagulants; Apgar Score; Cohort Studies; Enoxaparin; | 2012 |
Emerging nonanticoagulant role of low molecular weight heparins on extravillous trophoblast functions and on heparin binding-epidermal growth factor and cystein-rich angiogenic inducer 61 expression.
Topics: Abortion, Habitual; Anticoagulants; Cell Differentiation; Cell Movement; Cells, Cultured; Cysteine-R | 2012 |
Low molecular weight heparin for repeated pregnancy loss: is it based on solid evidence?
Topics: Abortion, Habitual; Clinical Protocols; Clinical Trials as Topic; Enoxaparin; Female; Heparin, Low-M | 2005 |
The long and winding road ... towards LMWH for pregnancy loss.
Topics: Abortion, Habitual; Clinical Protocols; Enoxaparin; Female; Heparin, Low-Molecular-Weight; Humans; P | 2005 |
Effects of enoxaparin on late pregnancy complications and neonatal outcome in women with recurrent pregnancy loss and thrombophilia: results from the Live-Enox study.
Topics: Abortion, Habitual; Enoxaparin; Female; Humans; Infant, Newborn; Live Birth; Pregnancy; Pregnancy Co | 2005 |
Thrombophilia and pregnancy loss in first intended pregnancy.
Topics: Abortion, Habitual; Abortion, Spontaneous; Enoxaparin; Female; Gravidity; Humans; Pregnancy; Pregnan | 2005 |
The natural course of women with recurrent fetal loss.
Topics: Abortion, Habitual; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Enoxaparin; Female; Fibrinolyt | 2006 |
Antithrombotic prophylaxis during pregnancy in women with deficiency of natural anticoagulants.
Topics: Abortion, Habitual; Adult; Anticoagulants; Cohort Studies; Enoxaparin; Female; Humans; Live Birth; P | 2008 |
The effect of thrombophylaxis on pregnancy outcome in patients with recurrent pregnancy loss associated with factor V Leiden mutation.
Topics: Abortion, Habitual; Adult; Anticoagulants; Aspirin; Drug Therapy, Combination; Enoxaparin; Factor V; | 2000 |
Gestational outcome in thrombophilic women with recurrent pregnancy loss treated by enoxaparin.
Topics: 3' Untranslated Regions; Abortion, Habitual; Activated Protein C Resistance; Adult; Anticoagulants; | 2000 |
[Treatment with enoxaparin adapted to the fertility programs in women with recurrent abortion and thrombophilia].
Topics: Abortion, Habitual; Adult; Biomarkers; Embryo Loss; Enoxaparin; Female; Fibrinolytic Agents; Heparin | 2001 |
Pharmacokinetic profile of a low-molecular weight heparin (reviparin) in pregnant patients. A prospective cohort study.
Topics: Abortion, Habitual; Anticoagulants; Body Weight; Cohort Studies; Factor Xa Inhibitors; Female; Hepar | 2000 |
Recurrent Massive Perivillous Fibrin Deposition and Chronic Intervillositis Treated With Heparin and Intravenous Immunoglobulin: A Case Report.
Topics: Abortion, Habitual; Abortion, Spontaneous; Adult; Anticoagulants; Aspirin; Chorionic Villi; Daltepar | 2017 |
Effects of Sildenafil Citrate and Heparin Treatments on Placental Cell Morphology in a Murine Model of Pregnancy Loss.
Topics: Abortion, Habitual; Animals; Anticoagulants; Dalteparin; Disease Models, Animal; Female; Lipopolysac | 2016 |
A longitudinal study of maternal dose response to low molecular weight heparin in pregnancy.
Topics: Abortion, Habitual; Analysis of Variance; Anticoagulants; Area Under Curve; Dalteparin; Dose-Respons | 2003 |
Dalteparin sodium injection treatment in patients with immunologic recurrent pregnancy loss.
Topics: Abortion, Habitual; Adult; Anticoagulants; Dalteparin; Female; Humans; Injections, Subcutaneous; Pre | 2000 |
Tinzaparin safety and efficacy in pregnancy.
Topics: Abortion, Habitual; Adolescent; Adult; Drug Hypersensitivity; Female; Fibrinolytic Agents; Hemorrhag | 2014 |