Page last updated: 2024-10-18

dalteparin and 2019 Novel Coronavirus Disease

dalteparin has been researched along with 2019 Novel Coronavirus Disease in 138 studies

Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)

Research Excerpts

ExcerptRelevanceReference
"Nonischemic CRVO with cystoid macular edema was diagnosed and an intravitreal injection of ranibizumab was performed."5.72Central Retinal Vein Occlusion After Discontinuation of Rivaroxaban Therapy in a Young Patient with COVID-19 Pulmonary Embolism: A Case Report. ( Biskup, M; Kal, M; Krupińska, J; Odrobina, D; Płatkowska-Adamska, B, 2022)
"The large outbreak of coronavirus disease 2019 (COVID-19) is spreading all over the world rapidly."5.62Effectiveness of lopinavir/ritonavir on COVID-19-related pneumonia in a child with COVID-19-associated Kawasaki disease. ( Akat, H; Laloglu, F; Orbak, Z, 2021)
"In this randomized, open-label, prospective superiority trial involving hospitalized patients with confirmed mild or moderate COVID-19 disease without known thromboembolism, we assigned 230 patients to receive either once-daily oral rivaroxaban (10mg or 15mg) or once-daily subcutaneous enoxaparin (40mg or 60mg) for a median duration of 8 days."5.51Oral Rivaroxaban in the Prophylaxis of COVID-19 Induced Coagulopathy. ( Chandralekha, S; Kaimaparambil, V; Kumar, D; Lalchandani, J, 2022)
"In patients hospitalised with COVID-19 and elevated D-dimer concentration, in-hospital therapeutic anticoagulation with rivaroxaban or enoxaparin followed by rivaroxaban to day 30 did not improve clinical outcomes and increased bleeding compared with prophylactic anticoagulation."5.41Therapeutic versus prophylactic anticoagulation for patients admitted to hospital with COVID-19 and elevated D-dimer concentration (ACTION): an open-label, multicentre, randomised, controlled trial. ( Alexander, JH; Armaganijan, L; Avezum, A; Azevedo, LCP; Barbosa, LM; Berwanger, O; Bronhara, B; Canesin, MF; Cavalcanti, AB; Conceição-Souza, GE; Damiani, LP; de Alcântara Chaud, MS; de Aquino Martins, P; de Aveiro Morata, J; de Barros E Silva, PGM; de Faria, LM; de Matos Soeiro, A; de Oliveira Twardowsky, A; de Oliveira, AL; de Souza Dantas, VC; Diaz, DRA; Dracoulakis, MDA; Feitosa-Filho, GS; Fernandes, ACS; Figueiredo, EL; Furtado, RHM; Gazzana, MB; Gebara, OCE; Guimarães, PO; Hernandes, ME; Lima, RGSD; Liporace, IL; Lopes, RD; Macedo, AVS; Machado, FR; Maia, LN; Melro, LMG; Neuenschwander, FC; Nunes, VS; Queiroz, DAR; Ramacciotti, E; Ritt, LEF; Rocha, AT; Rosa, RG; Santos, SV; Tramujas, L; Veiga, VC; Viana, LS, 2021)
"A 71-year old gentleman with history of arterial hypertension treated with valsartan presented on was hospitalized at the Infectious Diseases Unit, University of Bologna (Italy) for severe acute respiratory syndrome- coronavirus-2 (SARS-CoV-2) and received treatment with hydroxychloroquine 200mg bid (400 mg bid the first day), azithromycin 400 mg qd, thrombotic prophylaxis with enoxaparin 4000 UI qd and Venturi mask oxygen delivering FiO2 of 31%."3.96Clinical experience with therapeutic dose of Low-Molecular-Weight Heparin. ( Bartoletti, M; Viale, P, 2020)
" The aim of our study was to evaluate the clinical impact of venous thromboembolism prophylaxis with fondaparinux versus enoxaparin among 100 hospitalized COVID-19 patients."3.96Fondaparinux Use in Patients With COVID-19: A Preliminary Multicenter Real-World Experience. ( Agrusta, F; Amitrano, M; Bellizzi, A; Cardillo, G; Cavalli, A; Di Micco, P; Fontanella, A; Iannuzzo, M; Lodigiani, C; Mangiacapra, S; Russo, V; Sacco, C; Viggiano, GV, 2020)
"We report a case of ophthalmic artery occlusion (OAO) in a young patient with COVID-19 infection that was on therapeutic anticoagulation with apixaban for deep venous thrombosis (DVT)."3.96Acute ophthalmic artery occlusion in a COVID-19 patient on apixaban. ( Biousse, V; Bose, S; Dumitrascu, OM; Lyden, PD; Volod, O; Wang, Y, 2020)
"SARS-CoV-2 patients with acute respiratory distress syndrome show elevated fibrinogen activity, high D-dimer levels and maximum amplitude of clot strength."3.96Thromboelastography clot strength profiles and effect of systemic anticoagulation in COVID-19 acute respiratory distress syndrome: a prospective, observational study. ( Antonelli, M; Biasucci, DG; Bocci, MG; Carelli, S; Consalvo, LM; Cutuli, SL; De Candia, E; Franceschi, F; Gori, C; Grieco, DL; Maviglia, R; Mercurio, G; Montini, L; Nardi, G; Natalini, D; Pisapia, L; Rosenkranz, R, 2020)
"The study INHIXACOVID19 was registred on ClinicalTrials."3.30Intermediate dose enoxaparin in hospitalized patients with moderate-severe COVID-19: a pilot phase II single-arm study, INHIXACOVID19. ( Bignami, EG; Brambilla, P; Castagna, A; Cosmi, B; Cristini, F; De Stefano, G; Di Perri, G; Drago, F; Fornaro, G; Frattima, S; Giannella, M; Grandone, E; Lupi, M; Mazzaferri, F; Montineri, A; Pan, A; Patacca, A; Romagnoli, A; Rozzini, R; Salvetti, M; Stella, A; Testa, S; Viale, P, 2023)
"We aimed to evaluate the effectiveness and safety of enoxaparin compared with UFH when used at their standard/intermediate dosing in COVID-19 patients."3.30Effectiveness and Safety of Enoxaparin Versus Unfractionated Heparin as Thromboprophylaxis in Hospitalized COVID-19 Patients: Real-World Evidence. ( Abraham, I; Al Saeed, J; Al-Bassam, S; Al-Makki, S; Alamer, A; AlLehaibi, LH; Almulhim, A; Alomar, M; Alrwaili, NR; Alsheef, M; Alsultan, S, 2023)
"No DVT developed in COVID-19 patients hospitalized in general wards, independently of enoxaparin dosing used for thromboprophylaxis."3.11Enoxaparin for thromboprophylaxis in hospitalized COVID-19 patients: The X-COVID-19 Randomized Trial. ( Agostinis, M; Antolini, L; Barberis, D; Birocchi, S; Bonacchini, L; Carioti, G; Cattaneo, M; Gazzaniga, G; Grazia Valsecchi, M; Massaini, G; Merli, M; Morici, N; Podda, G; Saverio Serino, F; Trezzi, M, 2022)
" Optimal thromboprophylaxis dosing in high-risk patients is unknown."3.01Efficacy and Safety of Therapeutic-Dose Heparin vs Standard Prophylactic or Intermediate-Dose Heparins for Thromboprophylaxis in High-risk Hospitalized Patients With COVID-19: The HEP-COVID Randomized Clinical Trial. ( Agrawal, N; Anderson, VE; Bonaca, M; Cohen, M; Cohoon, KP; Diab, W; Giannis, D; Gianos, E; Goldin, M; Halperin, JL; Hsia, J; Khanijo, S; Lesser, ML; Lewis, PA; Lund, JM; Mignatti, A; Ochani, K; Rahman, H; Sharifova, G; Sison, CP; Spyropoulos, AC; Tafur, A; Wang, J; Weitz, JI, 2021)
"A 61-year old patient with ankylosing spondylitis who was on secukinumab therapy for 5 months admitted with newly onset fever and gastrointestinal complaints."2.66Coronavirus disease 2019 (COVID-19) in a patient with ankylosing spondylitis treated with secukinumab: a case-based review. ( Coskun Benlidayi, I; Guzel, R; Kurtaran, B; Tirasci, E, 2020)
" The absorption rate constant of nadroparin was 3."1.91Population Pharmacokinetics and Probability of Target Attainment Analysis of Nadroparin in Different Stages of COVID-19. ( Borys, M; Cios, W; Czuczwar, M; Okuńska, P; Piwowarczyk, P; Raszewski, G; Szczukocka, M; Wiczling, P, 2023)
" Furthermore, of the simulated regimens, targeted anti-Xa levels were most adequately achieved with a dosing regimen of 5700 IU BID."1.91Population pharmacokinetics of nadroparin for thromboprophylaxis in COVID-19 intensive care unit patients. ( Endeman, H; Hunfeld, NGM; Kruip, MJHA; Preijers, T; Romano, LGR, 2023)
"For discriminating arterial and venous thrombosis, there was no significant difference between the ADA vs."1.91External validation of the ADA score for predicting thrombosis among acutely ill hospitalized medical patients from the APEX Trial. ( Chi, G; Cohen, AT; Gibson, CM; Goldhaber, SZ; Harrington, RA; Hernandez, AF; Hull, RD; Loffredo, L; Pignatelli, P; Spagnoli, A; Vestri, A; Violi, F, 2023)
"BACKGROUND Coronavirus disease 2019 (COVID-19) has a tremendous impact on the respiratory tract."1.72A Patient-Tailored Approach to Management of Acute Limb Ischemia in Patients with COVID-19: A Case Series. ( AlGhofili, H; Alhumaid, A; Aljabri, B; Altoijry, A; Iqbal, K, 2022)
"Despite standard thromboprophylaxis, venous thrombosis is common in critically ill patients with COVID-19."1.72[Deep venous thrombosis incidence in patients with COVID-19 acute respiratory distress syndrome, under intermediate dose of chemical thromboprophylaxis]. ( Bonelli, I; Hunter, M; López Saubidet, I; Lurbet, MF; Mandó, F; Parodi, J; Rodríguez, PO, 2022)
"COVID-19 associated acute mesenteric ischemia is a complication with high mortality."1.72Acute Mesenteric Ischemia in COVID-19 While Receiving Prophylactic Enoxaparin. ( Surendran, SA; Sureshkumar, NB, 2022)
"Background: Severe progression of coronavirus disease 2019 (COVID-19) causes respiratory failure and critical illness."1.72HIGH HEPARANASE LEVEL IN SURVIVORS OF COVID-19 - INDICATOR OF VASCULAR AND PULMONARY RECOVERY? ( Adam, EH; Brkic, D; Heinicke, U; Neb, H; Ruskowski, K; Sonntagbauer, M; Talbot, SR; von Knethen, A; Zacharowski, K, 2022)
"Nonischemic CRVO with cystoid macular edema was diagnosed and an intravitreal injection of ranibizumab was performed."1.72Central Retinal Vein Occlusion After Discontinuation of Rivaroxaban Therapy in a Young Patient with COVID-19 Pulmonary Embolism: A Case Report. ( Biskup, M; Kal, M; Krupińska, J; Odrobina, D; Płatkowska-Adamska, B, 2022)
"The data from studies presenting cerebrovascular diseases associated with SARS-Cov-2, which constituted 0."1.72Coexistence of SARS-CoV-2 and cerebrovascular diseases: does COVID-19 positivity trigger cerebrovascular pathologies? ( Ates, O; Dogan, M; Ersoz, E; Hacioglu Kasim, FB; Karaarslan, N; Ozbek, H; Yilmaz, I, 2022)
" The inability of PED to adequately protect major circulating blood cells is probably due to enhanced clearance or/and diminished bioavailability of enoxaparin during COVID."1.62Enoxaparin dose impacts blood cell phenotypes during mild SARS-CoV-2 infection: the observational single-center study. ( Buryachkovskaya, L; Docenko, J; Ermishkin, V; Lomakin, N; Melkumyants, A; Serebruany, V, 2021)
"Penile thrombosis has not been reported as a thrombotic complication of SARS-CoV-2 infection with hypercoagulability."1.62Priapism in a patient with coronavirus disease 2019 (COVID-19). ( Abbad, S; Chebbi, A; Lamamri, M; Legriel, S; Mamane, J; Munuzzolini, M; Sarfati, F, 2021)
"The large outbreak of coronavirus disease 2019 (COVID-19) is spreading all over the world rapidly."1.62Effectiveness of lopinavir/ritonavir on COVID-19-related pneumonia in a child with COVID-19-associated Kawasaki disease. ( Akat, H; Laloglu, F; Orbak, Z, 2021)
"BACKGROUND Pandemic coronavirus disease 2019 (COVID-19) originated in Wuhan, China, and is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)."1.62Superficial Cerebral Venous Thrombosis and Intracerebral Hematoma in a 48-Year-Old Man with SARS-CoV-2 Infection: A Case Report. ( Bains, SS; Cardoso, ER; Farkas, J; Robison, B, 2021)
" At 21 days, the incidence rate of death and clinical deterioration were lower in patients on higher doses than in those on the standard dosage (hazard ratio 0."1.62Increasing dosages of low-molecular-weight heparin in hospitalized patients with Covid-19. ( Abbattista, M; Aliberti, S; Artoni, A; Blasi, F; Carrafiello, G; Ciavarella, A; De Zan, V; Folli, C; Gori, A; Grasselli, G; Ierardi, AM; Martinelli, I; Monzani, V; Panigada, M; Peyvandi, F, 2021)
" Accordingly, recent data suggested a beneficial role of low molecular weight heparin (LMWH), but the optimal dosage of this treatment is unknown."1.62Clinical outcome with different doses of low-molecular-weight heparin in patients hospitalized for COVID-19. ( Aimaretti, G; Avanzi, GC; Azzolina, D; Bellan, M; Cantaluppi, V; Capponi, A; Castello, LM; Cipollone, F; Colombo, C; Corte, FD; D'Ardes, D; Foglietta, M; Gallina, S; Grisafi, L; Hayden, E; Krengli, M; Lio, V; Malerba, M; Mennuni, MG; Patti, G; Petrilli, I; Pierdomenico, SD; Pirisi, M; Renda, G; Rognoni, A; Sainaghi, PP; Savoia, P; Spinoni, E; Zeppegno, P, 2021)
"Coronavirus is a source of deep venous thrombosis (DVT) due to complications such as over-coagulation, blood stasis, and endothelial damage."1.62Ovarian vein thrombosis after coronavirus disease (COVID-19) mimicking acute abdomen: two case reports. ( Abdeladim, S; Bensahi, I; Elouarradi, A; Fatimazahra, M; Harras, ME; Kassimi, M; Oualim, S; Sabry, M, 2021)
"To develop a pharmacokinetic model of enoxaparin to predict the time-exposure profiles of various thromboprophylactic regimens in COVID-19 ICU-patients."1.62Pharmacokinetics of enoxaparin in COVID-19 critically ill patients. ( Bauters, A; Caplan, M; Delavenne, X; Dupont, A; Goutay, J; Jean, L; Lanoiselée, J; Levy, L; Poissy, J; Susen, S; Zufferey, PJ, 2021)
" An antithrombotic prophylaxis at low dosage was immediately started, then increased at prophylactic dosage."1.56How haemophilia A impacts severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) treatment: a case report. ( Campello, E; Pasca, S; Simioni, P; Spiezia, L; Vettor, R; Zanon, E, 2020)
"Acute pulmonary embolism and coronavirus disease were diagnosed."1.56COVID-19 and Acute Pulmonary Embolism in Postpartum Patient. ( Boogar, SS; Khodamoradi, Z; Kouhi, P; Shirazi, FKH, 2020)
"Key words: Coronavirus disease 2019 (COVID-19), Meningoencephalitis, Pneumonia."1.56A Case of 45-Year Man Who Succumbed to Coronavirus Disease 2019 (COVID-19). ( Khan, MA, 2020)
"We present a late presentation of saddle pulmonary embolism and thrombus-in-transit straddle the patent foramen on patient who successfully recovered from severe acute respiratory syndrome coronavirus-2 (COVID-19) pneumonia."1.56Saddle pulmonary embolism and thrombus-in-transit straddling the patent foramen ovale 28 days after COVID symptom onset. ( Fontes, JD; Fujikura, K; Taub, CC, 2020)
"A chest CT scan showed an acute type B aortic dissection (ATBAD) and bilateral lung involvement with ground-glass opacity, compatible with interstitial pneumonia."1.56An infection-oriented approach for thoracic endovascular aortic repair in a SARS-CoV-2 positive patient. A case report. ( Ferrari, SA; Muzzarelli, L; Piconi, S; Rossi, G; Sommaruga, S, 2020)
" The purpose of the study was to evaluate the association between initial dosing strategy of thromboprophylaxis in critically ill COVID-19 patients and the risk of death, thromboembolism, and bleeding."1.56Dosing of thromboprophylaxis and mortality in critically ill COVID-19 patients. ( Cronhjort, M; Dahlberg, M; Everhov, ÅH; Grip, J; Günther, M; Hollenberg, J; Järnbert-Pettersson, H; Jonmarker, S; Litorell, J; Schandl, A; Söderberg, M; Stackelberg, O, 2020)

Research

Studies (138)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's138 (100.00)2.80

Authors

AuthorsStudies
Eck, RJ1
van de Leur, JJCM1
Wiersema, R1
Cox, EGM1
Bult, W1
Spanjersberg, AJ1
van der Horst, ICC1
Lukens, MV1
Gans, ROB1
Meijer, K1
Keus, F1
Romano, LGR2
Hunfeld, NGM2
Kruip, MJHA2
Endeman, H2
Preijers, T2
Piwowarczyk, P1
Szczukocka, M1
Cios, W1
Okuńska, P1
Raszewski, G1
Borys, M1
Wiczling, P1
Czuczwar, M1
Brüggemann, R1
Gietema, H1
Jallah, B1
Ten Cate, H1
Stehouwer, C1
Spaetgens, B1
Trunfio, M1
Salvador, E1
Cabodi, D1
Marinaro, L1
Alcantarini, C1
Gaviraghi, A1
Trentalange, A1
Lipani, F1
Sciascia, S1
Roccatello, D1
Bonora, S1
Di Perri, G2
Calcagno, A1
Marcos-Jubilar, M1
Carmona-Torre, F1
Vidal, R1
Ruiz-Artacho, P1
Filella, D1
Carbonell, C1
Jiménez-Yuste, V1
Schwartz, J1
Llamas, P1
Alegre, F1
Sádaba, B1
Núñez-Córdoba, J1
Yuste, JR1
Fernández-García, J1
Lecumberri, R1
Varona, JF1
Núñez, E1
Fernández Félix, BM1
Castellano Vázquez, JM1
Cubillo, A1
Lozano, R1
Franco, ME1
Doello, K1
Amezcua, V1
Sargin Altunok, E1
Satici, C1
Dinc, V1
Kamat, S2
Alkan, M1
Demirkol, MA1
Toprak, ID1
Kostek, ME1
Yazla, S1
Esatoglu, SN1
Spyropoulos, AC3
Goldin, M2
Giannis, D2
Diab, W2
Wang, J2
Khanijo, S2
Mignatti, A2
Gianos, E2
Cohen, M2
Sharifova, G2
Lund, JM2
Tafur, A2
Lewis, PA2
Cohoon, KP1
Rahman, H2
Sison, CP2
Lesser, ML2
Ochani, K2
Agrawal, N1
Hsia, J1
Anderson, VE2
Bonaca, M2
Halperin, JL2
Weitz, JI2
Marini, CP1
Lewis, E1
Petrone, P1
Zenilman, A1
Lu, Z1
Rivera, A1
McNelis, J1
Faour, WH1
Choaib, A1
Issa, E1
Choueiry, FE1
Shbaklo, K1
Alhajj, M1
Sawaya, RT1
Harhous, Z1
Alefishat, E1
Nader, M1
Daye, M1
Oltulu, P1
Buryachkovskaya, L1
Lomakin, N1
Melkumyants, A1
Docenko, J1
Ermishkin, V1
Serebruany, V1
Morici, N2
Podda, G1
Birocchi, S1
Bonacchini, L1
Merli, M1
Trezzi, M1
Massaini, G1
Agostinis, M1
Carioti, G1
Saverio Serino, F1
Gazzaniga, G1
Barberis, D1
Antolini, L1
Grazia Valsecchi, M1
Cattaneo, M2
Di Micco, P3
Imbalzano, E1
Russo, V3
Attena, E1
Mandaliti, V1
Orlando, L1
Lombardi, M1
Di Micco, G1
Camporese, G1
Annunziata, S1
Piccinocchi, G1
Pacelli, W1
Del Guercio, M1
Szydełko-Paśko, U1
Przeździecka-Dołyk, J1
Kręcicka, J1
Małecki, R1
Misiuk-Hojło, M1
Turno-Kręcicka, A1
Alhumaid, A1
Altoijry, A1
Aljabri, B1
Iqbal, K1
AlGhofili, H1
Keskin, H1
Keskin, F1
Yildirim, E1
Saritas, S1
Polat, G1
Colak, A1
Laloglu, F2
Guler, MA1
Ozay, M1
Alp, H1
Farkouh, ME2
Stone, GW4
Lala, A2
Bagiella, E1
Moreno, PR2
Nadkarni, GN2
Ben-Yehuda, O1
Granada, JF1
Dressler, O2
Tinuoye, EO1
Granada, C2
Bustamante, J2
Peyra, C2
Godoy, LC2
Palacios, IF2
Fuster, V2
Zaragoza-Huesca, D1
Martínez-Cortés, C1
Banegas-Luna, AJ1
Pérez-Garrido, A1
Vegara-Meseguer, JM1
Peñas-Martínez, J1
Rodenas, MC1
Espín, S1
Pérez-Sánchez, H1
Martínez-Martínez, I1
Calabretta, F1
Preti, PS1
Russo, M2
Klersy, C1
Di Sabatino, A1
Hunter, M1
Lurbet, MF1
Parodi, J1
Mandó, F1
Bonelli, I1
Rodríguez, PO1
López Saubidet, I1
Elikowski, W1
Fertała, N1
Zawodna-Marszałek, M1
Karoń, J1
Skrzywanek, P1
Mozer-Lisewska, I1
Szczęśniewski, P1
Łazowski, S1
Żytkiewicz, M1
Kumar, D1
Kaimaparambil, V1
Chandralekha, S1
Lalchandani, J1
Sochet, AA1
Morrison, JM1
Jaffray, J1
Godiwala, N1
Wilson, HP1
Thornburg, CD1
Bhat, RV1
Zia, A1
Lawrence, C1
Kudchadkar, SR1
Hamblin, F1
Russell, CJ1
Streiff, MB1
Amankwah, EK1
Goldenberg, NA1
Porres-Aguilar, M1
Anaya-Ayala, JE1
Barco, S5
Voci, D4
Held, U5
Sebastian, T5
Bingisser, R5
Colucci, G5
Duerschmied, D4
Frenk, A2
Gerber, B5
Götschi, A4
Konstantinides, SV4
Mach, F5
Robert-Ebadi, H4
Rosemann, T5
Simon, NR4
Spechbach, H1
Spirk, D4
Stortecky, S5
Vaisnora, L4
Righini, M6
Kucher, N5
Cools, F1
Virdone, S1
Sawhney, J1
Lopes, RD3
Jacobson, B1
Arcelus, JI1
Hobbs, FDR1
Gibbs, H1
Himmelreich, JCL1
MacCallum, P1
Schellong, S1
Haas, S1
Turpie, AGG1
Ageno, W1
Rocha, AT2
Kayani, G1
Pieper, K1
Kakkar, AK1
Ates, O1
Yilmaz, I1
Karaarslan, N1
Ersoz, E1
Hacioglu Kasim, FB1
Dogan, M1
Ozbek, H1
Mohamed, AS1
Ahmad, HM1
Abdul-Raheem, ASA1
Kamel, FMM1
Khames, A1
Mady, AF1
AlLehaibi, LH1
Alomar, M1
Almulhim, A1
Al-Makki, S1
Alrwaili, NR1
Al-Bassam, S1
Alsultan, S1
Al Saeed, J1
Alsheef, M1
Abraham, I1
Alamer, A1
Araldi, RP1
Prezoto, BC1
Gonzaga, V1
Policiquio, B1
Mendes, TB1
D'Amélio, F1
Vigerelli, H1
Viana, M1
Valverde, CW1
Pagani, E1
Kerkis, I1
Deokar, K1
Kaliya, M1
Vachhani, K1
Singhal, S1
Parekh, A1
Schiavina, M1
Pontoriero, L1
Tagliaferro, G1
Pierattelli, R1
Felli, IC1
Płatkowska-Adamska, B1
Kal, M1
Krupińska, J1
Biskup, M1
Odrobina, D1
Eder, J1
Bermejo-Jambrina, M1
Vlaming, KE1
Kaptein, TM1
Zaderer, V1
Kemper, EM1
Wilflingseder, D1
Reitsma, S1
de Bree, GJ1
Cohn, DM1
Geijtenbeek, TBH1
Fumagalli, RM3
Hasse, B3
Keller, DI3
Rampini, SK3
Roth-Zetzsche, S3
Albisinni, R2
Vitrone, M2
Ursi, MP2
Spiezia, S2
Salemme, A2
Florio, LL2
Boccia, F2
Iossa, D2
Zampino, R2
Atripaldi, L2
Squillante, F2
Maturo, N2
Fraganza, F2
Severino, S2
Punzi, R2
Fiorentino, G2
Masjedi, M1
Azadikhah, S1
Zand, F1
Asmarian, N1
Sabetian, G1
Ostovan, M1
Naderi-Boldaji, V1
Neb, H1
Talbot, SR1
Ruskowski, K1
Brkic, D1
Sonntagbauer, M1
Adam, EH1
von Knethen, A1
Zacharowski, K1
Heinicke, U1
Chi, G1
Violi, F1
Pignatelli, P1
Vestri, A1
Spagnoli, A1
Loffredo, L1
Hernandez, AF1
Hull, RD1
Cohen, AT1
Harrington, RA1
Goldhaber, SZ4
Gibson, CM1
Sureshkumar, NB1
Surendran, SA1
Afsharirad, B1
Entezari-Maleki, T1
Tinuoye, E1
Goodman, SG1
Esper, RB1
Abizaid, A1
Varade, D1
Betancur, JF1
Ricalde, A1
Payro, G1
Castellano, JM1
Hung, IFN1
Giustino, G1
Feinman, J1
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Clinical Trials (15)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Ensayo clínico Aleatorizado, Abierto, Para Evaluar el Efecto de Dosis profilácticas o terapéuticas de Bemiparina en Pacientes Con COVID-19[NCT04604327]Phase 3164 participants (Anticipated)Interventional2020-10-26Recruiting
Systemic Anticoagulation With Full Dose Low Molecular Weight Heparin (LMWH) Vs. Prophylactic or Intermediate Dose LMWH in High Risk COVID-19 Patients (HEP-COVID Trial)[NCT04401293]Phase 3257 participants (Actual)Interventional2020-04-26Completed
FREEDOM COVID Anticoagulation Strategy Randomized Trial[NCT04512079]Phase 43,460 participants (Actual)Interventional2020-09-08Completed
COVID-19 Anticoagulation in Children - Thromboprophlaxis (COVAC-TP) Trial[NCT04354155]Phase 240 participants (Actual)Interventional2020-06-02Completed
Enoxaparin for Primary Thromboprophylaxis in Ambulatory Patients With Coronavirus: The Multicenter Randomized Controlled Ovid Trial[NCT04400799]Phase 3475 participants (Actual)Interventional2020-06-15Terminated (stopped due to due to results from interim analysis)
Early Thromboprophylaxis in COVID-19 (ETHIC Trial): an Open Label, Randomized Phase IIIb Trial of Community-based (LMWH) Versus Standard of Care (no Enoxaparin) in COVID-19 Positive Patients[NCT04492254]Phase 3219 participants (Actual)Interventional2020-10-27Terminated (stopped due to Average event rate (end point) was much lower than expected. A larger sample size would have been required to maintain same statistical power, which was not achievable in a feasible time scale. No safety concerns were identified with bleeding.)
The Role of Ischemia Modified Albumin in Patients With COVID-19[NCT05286268]194 participants (Anticipated)Observational2022-04-06Recruiting
Intermediate-dose Versus Standard Prophylactic Anticoagulation In cRitically-ill pATIents With COVID-19: An opeN Label Randomized Controlled Trial---A Randomized Trial of Atorvastatin vs. Placebo In Critically-ill Patients With COVID-19[NCT04486508]Phase 3600 participants (Actual)Interventional2020-07-30Completed
Viral Infection and Respiratory Illness Universal Study[VIRUS]: COVID-19 Registry and Validation of C2D2 (Critical Care Data Dictionary)[NCT04323787]100,000 participants (Anticipated)Observational2020-03-30Recruiting
Prospective Two-week Open-label Application Experimental Randomized Single-center Non-interventional Study of the Drug Ingaron in Patients With a New Coronavirus Infection COVID-19[NCT05386459]36 participants (Actual)Observational2020-04-21Completed
Evaluation of the Effect of Exogenous Surfactant Through Nebulizer Mask on Clinical Outcomes in Covid-19 Patients[NCT04847375]60 participants (Anticipated)Interventional2021-04-20Not yet recruiting
Randomized Clinical Trial to Evaluate a Routine Full Anticoagulation Strategy in Patients With Coronavirus (COVID-19) - COALIZAO ACTION Trial[NCT04394377]Phase 4615 participants (Actual)Interventional2020-06-21Completed
Cellular Effects of SARS-CoV-2 in Mediating Thrombotic Susceptibility[NCT05334615]60 participants (Anticipated)Observational2022-01-21Recruiting
Dynamics of Hemostatic Parameters in COVID-19 and Comparison of Intervention Strategies Through Adaptive Clinical Trial[NCT04466670]Phase 2379 participants (Anticipated)Interventional2020-07-11Recruiting
Patient Characteristics, Outcome and Thromboembolic Events Among Adult Critically Ill COVID-19 Patients With Different Anticoagulant Regimes at One of the Biggest Emergency Hospitals in Northern Europe, Sweden[NCT04412304]166 participants (Actual)Observational2020-03-06Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Composite Outcome of Arterial Thromboembolic Events, Venous Thromboembolic Events and All-cause Mortality at Day 30 ± 2 Days.

Risk of arterial thromboembolic events (including myocardial infarction, stroke, systemic embolism), venous thromboembolism (including symptomatic deep vein thrombosis (DVT) of the upper or lower extremity, asymptomatic proximal DVT of the lower extremity, non-fatal pulmonary embolism (PE)), and all-cause mortality at Day 30 ± 2 days. (NCT04401293)
Timeframe: Day 30 ± 2 days

InterventionParticipants (Count of Participants)
Full Dose LMWH Anticoagulation Therapy25
Prophylactic/Intermediate Dose LMWH or UFH Therapy31

Composite Outcome of Arterial Thromboembolic Events, Venous Thromboembolic Events and All-cause Mortality at Hospital Day 10 + 4

The composite of arterial thromboembolic events (including myocardial infarction, stroke, systemic embolism), venous thromboembolism (including symptomatic deep vein thrombosis (DVT) of the upper or lower extremity, asymptomatic proximal DVT of the lower extremity, non-fatal pulmonary embolism (PE)), and all-cause mortality at Hospital Day 10 + 4 (NCT04401293)
Timeframe: Day 10 + 4

InterventionParticipants (Count of Participants)
Full Dose LMWH Anticoagulation Therapy2
Prophylactic/Intermediate Dose LMWH or UFH Therapy3

Major Bleeding

Risk of major bleeding defined using the International Society of Thrombosis and Haemostasis (ISTH) criteria (NCT04401293)
Timeframe: Day 30 ± 2 days

InterventionParticipants (Count of Participants)
Full Dose LMWH Anticoagulation Therapy6
Prophylactic/Intermediate Dose LMWH or UFH Therapy2

Need for Intubation

Need for Intubation will be based on monitoring of patient conditions. (NCT04401293)
Timeframe: Day 30 ± 2 days.

InterventionParticipants (Count of Participants)
Full Dose LMWH Anticoagulation Therapy17
Prophylactic/Intermediate Dose LMWH or UFH Therapy21

Progression to Acute Respiratory Distress Syndrome (ARDS)

Progression to Acute Respiratory Distress Syndrome (ARDS) based on monitoring of patient conditions. (NCT04401293)
Timeframe: Day 30 ± 2 days.

InterventionParticipants (Count of Participants)
Full Dose LMWH Anticoagulation Therapy11
Prophylactic/Intermediate Dose LMWH or UFH Therapy6

Re-hospitalization

Need for Re-hospitalization will be based on monitoring of patient conditions. (NCT04401293)
Timeframe: Day 30 ± 2 days.

InterventionParticipants (Count of Participants)
Full Dose LMWH Anticoagulation Therapy1
Prophylactic/Intermediate Dose LMWH or UFH Therapy3

Sepsis-induced Coagulopathy (SIC) Score

"Sepsis-induced coagulopathy (SIC) score predicts likelihood of sepsis-induced coagulopathy based on ISTH guidelines.~The score uses the following domains:~Platelets, K/uL (thousands per microliter)~INR (International Normalized Ratio)~D-Dimer Level~Fibrinogen~Platelet count > 100 cells x 10^9/L is 0 points, platelet count 50 to 100 cells x 10^9/L is 1 point and Platelet count < 50 cells x 10^9/L is 2 points. INR < 1.3 is 0 points, INR 1.3 to 1.7 is 1 point and INR > 1.7 is 2 points. D-Dimer level < 400 ng/mL is 0 points, D-Dimer level 400-4000 ng/mL is 2 points and D-Dimer level > 4000 ng/mL is 3 points. Fibrinogen level > 100 mg/dL is 0 points and fibrinogen level < 100 mg/dL is 1 point.~Calculated (SIC) scores yields a possible 0 to 6 points, where ≥4 predicts higher mortality rates within 30 days and greater risk of pulmonary embolism." (NCT04401293)
Timeframe: Day 30 ± 2 days.

Interventionunits on a scale (Mean)
Full Dose LMWH Anticoagulation Therapy2.35
Prophylactic/Intermediate Dose LMWH or UFH Therapy2.31

Efficacy of In-hospital Thromboprophylaxis as Measured by Number of Participants With Confirmed HA-VTE

To investigate, on a preliminary basis, the efficacy of in-hospital thromboprophylaxis with twice-daily enoxaparin in children hospitalized with COVID-19, as measured by number of participants with confirmed HA-VTE. (NCT04354155)
Timeframe: Day 30

InterventionParticipants (Count of Participants)
Thromboprophylaxis2

Safety of In-hospital Thromboprophylaxis as Assessed by Number of Participants With ISTH-defined Clinically-relevant Bleeding Events During Hospitalization

"The safety of in-hospital thromboprophylaxis with twice-daily low-dose enoxaparin thromboprophylaxis will be measured by cumulative incidence (number of participants) of ISTH-defined clinically-relevant bleeding events during hospitalization. Clinically relevant bleeding episodes may include any of the following:~fatal bleeding;~clinically overt bleeding associated with a decline in hemoglobin of ≥2g/dL in a 24h period;~retroperitoneal, pulmonary, or central nervous system bleeding;~bleeding requiring surgical intervention in an operating suite;~bleeding for which a blood product is administered (blood product administration not directly attributable to the patient's underlying condition);~bleeding that requires medical or surgical intervention to restore hemostasis, other than in an operating suite." (NCT04354155)
Timeframe: Day 30

InterventionParticipants (Count of Participants)
Thromboprophylaxis0

Median Twice-daily Enoxaparin Dose Required to Achieve 4-hour Post-dose Anti-factor Xa Between 0.20-0.49 U/mL

The median twice-daily enoxaparin dose, as measured in mg/kg, required to achieve a 4-hour post-dose anti-factor Xa level of 0.20-0.49 anti-Xa U/mL in children hospitalized with COVID-19, and to compare dose-requirements by age group (<12 and those >12 years of age). (NCT04354155)
Timeframe: 4 hours post initial dose

Interventionmg/kg (Median)
Children 12 years or olderChildren less than 12 years
Thromboprophylaxis0.50.52

Reviews

8 reviews available for dalteparin and 2019 Novel Coronavirus Disease

ArticleYear
Mechanisms of COVID-19-induced kidney injury and current pharmacotherapies.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2022, Volume: 71, Issue:1

    Topics: Acute Kidney Injury; Aldosterone; Angiotensins; Antibodies, Monoclonal, Humanized; Autopsy; Biopsy;

2022
Heparin and SARS-CoV-2: Multiple Pathophysiological Links.
    Viruses, 2021, 12-11, Volume: 13, Issue:12

    Topics: Anticoagulants; COVID-19; Enoxaparin; Fondaparinux; Hemorrhage; Heparin; Heparin, Low-Molecular-Weig

2021
Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week.
    Journal of the American College of Cardiology, 2022, 03-08, Volume: 79, Issue:9

    Topics: Anticoagulants; COVID-19; Critical Care; Enoxaparin; Hospitalization; Humans; Pyrazoles; Pyridones;

2022
Enoxaparin for COVID-19: a systematic review and meta-analysis of randomized controlled trials.
    Journal of thrombosis and thrombolysis, 2023, Volume: 56, Issue:3

    Topics: Anticoagulants; COVID-19; Enoxaparin; Humans; Randomized Controlled Trials as Topic; Venous Thromboe

2023
Scientific considerations in the regulatory approval of generic (or biosimilar) version of enoxaparin sodium - A lifesaving carbohydrate polymer.
    Regulatory toxicology and pharmacology : RTP, 2023, Volume: 143

    Topics: Animals; Biosimilar Pharmaceuticals; COVID-19; Drug Approval; Drugs, Generic; Enoxaparin; Humans; Ph

2023
Coronavirus disease 2019 (COVID-19) in a patient with ankylosing spondylitis treated with secukinumab: a case-based review.
    Rheumatology international, 2020, Volume: 40, Issue:10

    Topics: Antibodies, Monoclonal, Humanized; Anticoagulants; Antirheumatic Agents; Betacoronavirus; Coronaviru

2020
Low-dose radiotherapy for COVID-19 pneumonia treatment: case report, procedure, and literature review.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2020, Volume: 196, Issue:12

    Topics: Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; Anticoagulants; Antiviral Agents; Combined

2020
Tinzaparin-a review of its molecular profile, pharmacology, special properties, and clinical uses.
    European journal of clinical pharmacology, 2022, Volume: 78, Issue:10

    Topics: Aged; Anticoagulants; COVID-19; Female; Heparin; Heparin, Low-Molecular-Weight; Humans; Pregnancy; T

2022

Trials

22 trials available for dalteparin and 2019 Novel Coronavirus Disease

ArticleYear
Therapeutic versus Prophylactic Bemiparin in Hospitalized Patients with Nonsevere COVID-19 Pneumonia (BEMICOP Study): An Open-Label, Multicenter, Randomized, Controlled Trial.
    Thrombosis and haemostasis, 2022, Volume: 122, Issue:2

    Topics: Aged; COVID-19; COVID-19 Drug Treatment; Female; Fibrin Fibrinogen Degradation Products; Heparin, Lo

2022
Efficacy and Safety of Therapeutic-Dose Heparin vs Standard Prophylactic or Intermediate-Dose Heparins for Thromboprophylaxis in High-risk Hospitalized Patients With COVID-19: The HEP-COVID Randomized Clinical Trial.
    JAMA internal medicine, 2021, 12-01, Volume: 181, Issue:12

    Topics: Adult; Aged; Anticoagulants; COVID-19; Enoxaparin; Female; Fibrin Fibrinogen Degradation Products; H

2021
Enoxaparin for thromboprophylaxis in hospitalized COVID-19 patients: The X-COVID-19 Randomized Trial.
    European journal of clinical investigation, 2022, Volume: 52, Issue:5

    Topics: Anticoagulants; COVID-19; Enoxaparin; Hemorrhage; Humans; Pulmonary Embolism; Venous Thromboembolism

2022
Oral Rivaroxaban in the Prophylaxis of COVID-19 Induced Coagulopathy.
    The Journal of the Association of Physicians of India, 2022, Volume: 70, Issue:2

    Topics: Anticoagulants; COVID-19; Enoxaparin; Hemorrhage; Humans; Prospective Studies; Rivaroxaban; Thromboe

2022
Enoxaparin Thromboprophylaxis in Children Hospitalized for COVID-19: A Phase 2 Trial.
    Pediatrics, 2022, 07-01, Volume: 150, Issue:1

    Topics: Anticoagulants; Child; COVID-19; Enoxaparin; Hemorrhage; Humans; Prospective Studies; Systemic Infla

2022
Enoxaparin for primary thromboprophylaxis in symptomatic outpatients with COVID-19 (OVID): a randomised, open-label, parallel-group, multicentre, phase 3 trial.
    The Lancet. Haematology, 2022, Volume: 9, Issue:8

    Topics: Aged; COVID-19; Enoxaparin; Female; Humans; Male; Middle Aged; Outpatients; SARS-CoV-2; Thrombosis;

2022
Thromboprophylactic low-molecular-weight heparin versus standard of care in unvaccinated, at-risk outpatients with COVID-19 (ETHIC): an open-label, multicentre, randomised, controlled, phase 3b trial.
    The Lancet. Haematology, 2022, Volume: 9, Issue:8

    Topics: COVID-19; COVID-19 Vaccines; Enoxaparin; Female; Hemorrhage; Heparin, Low-Molecular-Weight; Humans;

2022
Effectiveness and Safety of Enoxaparin Versus Unfractionated Heparin as Thromboprophylaxis in Hospitalized COVID-19 Patients: Real-World Evidence.
    The Annals of pharmacotherapy, 2023, Volume: 57, Issue:4

    Topics: Adolescent; Anticoagulants; COVID-19; Enoxaparin; Heparin; Humans; Retrospective Studies; Treatment

2023
Enoxaparin for outpatients with COVID-19: 90-day results from the randomised, open-label, parallel-group, multinational, phase III OVID trial.
    Thrombosis research, 2023, Volume: 221

    Topics: Adult; Anticoagulants; Cardiovascular Diseases; COVID-19; Enoxaparin; Female; Humans; Male; Middle A

2023
Enoxaparin for outpatients with COVID-19: 90-day results from the randomised, open-label, parallel-group, multinational, phase III OVID trial.
    Thrombosis research, 2023, Volume: 221

    Topics: Adult; Anticoagulants; Cardiovascular Diseases; COVID-19; Enoxaparin; Female; Humans; Male; Middle A

2023
Enoxaparin for outpatients with COVID-19: 90-day results from the randomised, open-label, parallel-group, multinational, phase III OVID trial.
    Thrombosis research, 2023, Volume: 221

    Topics: Adult; Anticoagulants; Cardiovascular Diseases; COVID-19; Enoxaparin; Female; Humans; Male; Middle A

2023
Enoxaparin for outpatients with COVID-19: 90-day results from the randomised, open-label, parallel-group, multinational, phase III OVID trial.
    Thrombosis research, 2023, Volume: 221

    Topics: Adult; Anticoagulants; Cardiovascular Diseases; COVID-19; Enoxaparin; Female; Humans; Male; Middle A

2023
Enoxaparin for outpatients with COVID-19: 90-day results from the randomised, open-label, parallel-group, multinational, phase III OVID trial.
    Thrombosis research, 2023, Volume: 221

    Topics: Adult; Anticoagulants; Cardiovascular Diseases; COVID-19; Enoxaparin; Female; Humans; Male; Middle A

2023
Enoxaparin for outpatients with COVID-19: 90-day results from the randomised, open-label, parallel-group, multinational, phase III OVID trial.
    Thrombosis research, 2023, Volume: 221

    Topics: Adult; Anticoagulants; Cardiovascular Diseases; COVID-19; Enoxaparin; Female; Humans; Male; Middle A

2023
Enoxaparin for outpatients with COVID-19: 90-day results from the randomised, open-label, parallel-group, multinational, phase III OVID trial.
    Thrombosis research, 2023, Volume: 221

    Topics: Adult; Anticoagulants; Cardiovascular Diseases; COVID-19; Enoxaparin; Female; Humans; Male; Middle A

2023
Enoxaparin for outpatients with COVID-19: 90-day results from the randomised, open-label, parallel-group, multinational, phase III OVID trial.
    Thrombosis research, 2023, Volume: 221

    Topics: Adult; Anticoagulants; Cardiovascular Diseases; COVID-19; Enoxaparin; Female; Humans; Male; Middle A

2023
Enoxaparin for outpatients with COVID-19: 90-day results from the randomised, open-label, parallel-group, multinational, phase III OVID trial.
    Thrombosis research, 2023, Volume: 221

    Topics: Adult; Anticoagulants; Cardiovascular Diseases; COVID-19; Enoxaparin; Female; Humans; Male; Middle A

2023
Randomized Trial of Anticoagulation Strategies for Noncritically Ill Patients Hospitalized With COVID-19.
    Journal of the American College of Cardiology, 2023, 05-09, Volume: 81, Issue:18

    Topics: Anticoagulants; Blood Coagulation; COVID-19; Enoxaparin; Humans; Thromboembolism

2023
Intermediate dose enoxaparin in hospitalized patients with moderate-severe COVID-19: a pilot phase II single-arm study, INHIXACOVID19.
    BMC infectious diseases, 2023, Oct-24, Volume: 23, Issue:1

    Topics: Anticoagulants; COVID-19; Enoxaparin; Hemorrhage; Heparin; Humans; Prospective Studies; Treatment Ou

2023
Enoxaparin for primary thromboprophylaxis in ambulatory patients with coronavirus disease-2019 (the OVID study): a structured summary of a study protocol for a randomized controlled trial.
    Trials, 2020, Sep-09, Volume: 21, Issue:1

    Topics: Anticoagulants; Betacoronavirus; Blood Coagulation; Coronavirus Infections; COVID-19; Enoxaparin; Eq

2020
Therapeutic versus prophylactic anticoagulation for severe COVID-19: A randomized phase II clinical trial (HESACOVID).
    Thrombosis research, 2020, Volume: 196

    Topics: Adult; Aged; Anticoagulants; Brazil; COVID-19; COVID-19 Drug Treatment; Drug Administration Schedule

2020
Intermediate versus standard-dose prophylactic anticoagulation and statin therapy versus placebo in critically-ill patients with COVID-19: Rationale and design of the INSPIRATION/INSPIRATION-S studies.
    Thrombosis research, 2020, Volume: 196

    Topics: Anticoagulants; Atorvastatin; COVID-19; COVID-19 Drug Treatment; Critical Illness; Double-Blind Meth

2020
[Interferon gamma in the treatment of patients with moderate COVID-19].
    Voprosy virusologii, 2021, 03-07, Volume: 66, Issue:1

    Topics: Aged; Ampicillin; Anti-Infective Agents; Anticoagulants; Azithromycin; Blood Pressure; COVID-19; COV

2021
Effect of Intermediate-Dose vs Standard-Dose Prophylactic Anticoagulation on Thrombotic Events, Extracorporeal Membrane Oxygenation Treatment, or Mortality Among Patients With COVID-19 Admitted to the Intensive Care Unit: The INSPIRATION Randomized Clinic
    JAMA, 2021, 04-27, Volume: 325, Issue:16

    Topics: Aged; Anticoagulants; COVID-19; Drug Administration Schedule; Enoxaparin; Extracorporeal Membrane Ox

2021
Effect of Intermediate-Dose vs Standard-Dose Prophylactic Anticoagulation on Thrombotic Events, Extracorporeal Membrane Oxygenation Treatment, or Mortality Among Patients With COVID-19 Admitted to the Intensive Care Unit: The INSPIRATION Randomized Clinic
    JAMA, 2021, 04-27, Volume: 325, Issue:16

    Topics: Aged; Anticoagulants; COVID-19; Drug Administration Schedule; Enoxaparin; Extracorporeal Membrane Ox

2021
Effect of Intermediate-Dose vs Standard-Dose Prophylactic Anticoagulation on Thrombotic Events, Extracorporeal Membrane Oxygenation Treatment, or Mortality Among Patients With COVID-19 Admitted to the Intensive Care Unit: The INSPIRATION Randomized Clinic
    JAMA, 2021, 04-27, Volume: 325, Issue:16

    Topics: Aged; Anticoagulants; COVID-19; Drug Administration Schedule; Enoxaparin; Extracorporeal Membrane Ox

2021
Effect of Intermediate-Dose vs Standard-Dose Prophylactic Anticoagulation on Thrombotic Events, Extracorporeal Membrane Oxygenation Treatment, or Mortality Among Patients With COVID-19 Admitted to the Intensive Care Unit: The INSPIRATION Randomized Clinic
    JAMA, 2021, 04-27, Volume: 325, Issue:16

    Topics: Aged; Anticoagulants; COVID-19; Drug Administration Schedule; Enoxaparin; Extracorporeal Membrane Ox

2021
Treatment-Dose LMWH versus Prophylactic/Intermediate Dose Heparins in High-Risk COVID-19 Inpatients: Rationale and Design of the HEP-COVID Trial.
    Thrombosis and haemostasis, 2021, Volume: 121, Issue:12

    Topics: Anticoagulants; Clinical Trials, Phase III as Topic; COVID-19; COVID-19 Drug Treatment; Enoxaparin;

2021
Intermediate-Dose versus Standard-Dose Prophylactic Anticoagulation in Patients with COVID-19 Admitted to the Intensive Care Unit: 90-Day Results from the INSPIRATION Randomized Trial.
    Thrombosis and haemostasis, 2022, Volume: 122, Issue:1

    Topics: Aged; Anticoagulants; Cohort Studies; COVID-19; COVID-19 Drug Treatment; Critical Care; Dose-Respons

2022
Randomized clinical trial to evaluate a routine full anticoagulation Strategy in Patients with Coronavirus Infection (SARS-CoV2) admitted to hospital: Rationale and design of the ACTION (AntiCoagulaTlon cOroNavirus)-Coalition IV trial.
    American heart journal, 2021, Volume: 238

    Topics: Administration, Oral; Anticoagulants; Brazil; COVID-19; Drug Administration Schedule; Enoxaparin; Fi

2021
Therapeutic versus prophylactic anticoagulation for patients admitted to hospital with COVID-19 and elevated D-dimer concentration (ACTION): an open-label, multicentre, randomised, controlled trial.
    Lancet (London, England), 2021, 06-12, Volume: 397, Issue:10291

    Topics: Adult; Aged; Anticoagulants; Blood Coagulation; Brazil; COVID-19; COVID-19 Drug Treatment; Endpoint

2021
Standard prophylactic versus intermediate dose enoxaparin in adults with severe COVID-19: A multi-center, open-label, randomized controlled trial.
    Journal of thrombosis and haemostasis : JTH, 2021, Volume: 19, Issue:9

    Topics: Adult; Anticoagulants; COVID-19; Enoxaparin; Female; Humans; Male; SARS-CoV-2; Thrombosis

2021
Nebulization with alkaline hipertonic ibuprofen induces a rapid increase in platelets circulating in COVID-19 patients but not in healthy subjects.
    Platelets, 2022, Apr-03, Volume: 33, Issue:3

    Topics: Adult; Blood Platelets; COVID-19; COVID-19 Drug Treatment; Enoxaparin; Female; Humans; Ibuprofen; Ma

2022

Other Studies

108 other studies available for dalteparin and 2019 Novel Coronavirus Disease

ArticleYear
Trough anti-Xa activity after intermediate dose nadroparin for thrombosis prophylaxis in critically ill patients with COVID-19 and acute kidney injury.
    Scientific reports, 2022, 10-18, Volume: 12, Issue:1

    Topics: Acute Kidney Injury; Anticoagulants; COVID-19; Critical Illness; Humans; Nadroparin; Prospective Stu

2022
Population pharmacokinetics of nadroparin for thromboprophylaxis in COVID-19 intensive care unit patients.
    British journal of clinical pharmacology, 2023, Volume: 89, Issue:5

    Topics: Anti-Bacterial Agents; Anticoagulants; COVID-19; Critical Illness; Humans; Inflammation; Intensive C

2023
Population pharmacokinetics of nadroparin for thromboprophylaxis in COVID-19 intensive care unit patients.
    British journal of clinical pharmacology, 2023, Volume: 89, Issue:5

    Topics: Anti-Bacterial Agents; Anticoagulants; COVID-19; Critical Illness; Humans; Inflammation; Intensive C

2023
Population pharmacokinetics of nadroparin for thromboprophylaxis in COVID-19 intensive care unit patients.
    British journal of clinical pharmacology, 2023, Volume: 89, Issue:5

    Topics: Anti-Bacterial Agents; Anticoagulants; COVID-19; Critical Illness; Humans; Inflammation; Intensive C

2023
Population pharmacokinetics of nadroparin for thromboprophylaxis in COVID-19 intensive care unit patients.
    British journal of clinical pharmacology, 2023, Volume: 89, Issue:5

    Topics: Anti-Bacterial Agents; Anticoagulants; COVID-19; Critical Illness; Humans; Inflammation; Intensive C

2023
Population Pharmacokinetics and Probability of Target Attainment Analysis of Nadroparin in Different Stages of COVID-19.
    Clinical pharmacokinetics, 2023, Volume: 62, Issue:6

    Topics: Anticoagulants; COVID-19; Humans; Nadroparin

2023
Arterial and venous thromboembolic disease in a patient with COVID-19: A case report.
    Thrombosis research, 2020, Volume: 191

    Topics: Anticoagulants; Cerebral Infarction; Clopidogrel; Computed Tomography Angiography; Coronavirus Infec

2020
Anti-Xa monitoring improves low-molecular-weight heparin effectiveness in patients with SARS-CoV-2 infection.
    Thrombosis research, 2020, Volume: 196

    Topics: Aged; Aged, 80 and over; Anticoagulants; Biomarkers; Blood Coagulation; COVID-19; COVID-19 Drug Trea

2020
Efficacy and safety of therapeutic vs. prophylactic bemiparin in noncritically ill patients with COVID-19 pneumonia.
    European journal of internal medicine, 2022, Volume: 99

    Topics: Anticoagulants; COVID-19; Heparin, Low-Molecular-Weight; Humans

2022
[Incidence of heparin-induced thrombocytopenia in patients with 2019 coronavirus disease].
    Medicina clinica, 2020, 11-13, Volume: 155, Issue:9

    Topics: Aged; Aged, 80 and over; Anticoagulants; Betacoronavirus; Coronavirus Infections; COVID-19; Female;

2020
Effect of adding bemiparin and cefepime to routine treatment in cancer patients with SARS-CoV-2 infection.
    Medicina clinica, 2021, 09-24, Volume: 157, Issue:6

    Topics: Cefepime; COVID-19; Heparin, Low-Molecular-Weight; Humans; Neoplasms; SARS-CoV-2

2021
Comparison of demographic and clinical characteristics of hospitalized COVID-19 patients with severe/critical illness in the first wave versus the second wave.
    Journal of medical virology, 2022, Volume: 94, Issue:1

    Topics: Aged; Amides; Antibodies, Monoclonal, Humanized; Azithromycin; C-Reactive Protein; Comorbidity; COVI

2022
Incidence and effects of deep vein thrombosis on the outcome of patients with coronavirus disease 2019 infection.
    Journal of vascular surgery. Venous and lymphatic disorders, 2022, Volume: 10, Issue:4

    Topics: Adult; Aged; Anticoagulants; COVID-19; Enoxaparin; Female; Humans; Incidence; Male; Middle Aged; Pul

2022
An AGEP case due to COVİD-19 or favipiravir or enoxaparin.
    Journal of cosmetic dermatology, 2022, Volume: 21, Issue:1

    Topics: Amides; COVID-19; Enoxaparin; Humans; Pyrazines; SARS-CoV-2

2022
Enoxaparin dose impacts blood cell phenotypes during mild SARS-CoV-2 infection: the observational single-center study.
    Reviews in cardiovascular medicine, 2021, 12-22, Volume: 22, Issue:4

    Topics: Anticoagulants; Blood Platelets; COVID-19; Enoxaparin; Humans; Phenotype; Retrospective Studies; SAR

2021
Arteritic Anterior Ischemic Optic Neuropathy in the Course of Giant Cell Arteritis After COVID-19.
    The American journal of case reports, 2022, Jan-11, Volume: 23

    Topics: Aged; COVID-19; Enoxaparin; Female; Giant Cell Arteritis; Humans; Optic Neuropathy, Ischemic; SARS-C

2022
A Patient-Tailored Approach to Management of Acute Limb Ischemia in Patients with COVID-19: A Case Series.
    The American journal of case reports, 2022, Feb-07, Volume: 23

    Topics: Adult; Aged; Arterial Occlusive Diseases; COVID-19; Enoxaparin; Female; Humans; Ischemia; Male; Midd

2022
Case of Venous Thromboembolia Under Enoxaparin Prophylaxis After Recovering From Acute Ischemic Stroke in Consequence of COVID-19-Related MIS-C.
    The Pediatric infectious disease journal, 2022, 05-01, Volume: 41, Issue:5

    Topics: Anticoagulants; Brain Ischemia; COVID-19; Enoxaparin; Humans; Ischemic Stroke; Systemic Inflammatory

2022
Identification of Kukoamine A, Zeaxanthin, and Clexane as New Furin Inhibitors.
    International journal of molecular sciences, 2022, Mar-03, Volume: 23, Issue:5

    Topics: Amino Acid Chloromethyl Ketones; Catalytic Domain; Cell Line, Tumor; Cell Survival; COVID-19; Enoxap

2022
The role of heparin in reducing in-hospital complications and three-month mortality rates in hospitalized COVID-19 patients.
    European journal of internal medicine, 2022, Volume: 101

    Topics: Anticoagulants; COVID-19; Enoxaparin; Heparin; Hospitals; Humans

2022
[Deep venous thrombosis incidence in patients with COVID-19 acute respiratory distress syndrome, under intermediate dose of chemical thromboprophylaxis].
    Medicina, 2022, Volume: 82, Issue:2

    Topics: Anticoagulants; COVID-19; Cross-Sectional Studies; Enoxaparin; Humans; Incidence; Respiratory Distre

2022
Retroperitoneal hematoma in COVID-19 patients - case series.
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2022, Apr-19, Volume: 50, Issue:296

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; COVID-19; Enoxaparin; Female; Hematoma; Heparin, Low

2022
[Comment on article "Enoxaparin dose associated with decreased risk of death in COVID-19"].
    Revista medica del Instituto Mexicano del Seguro Social, 2022, May-02, Volume: 60, Issue:3

    Topics: Anticoagulants; COVID-19; Enoxaparin; Humans

2022
Coexistence of SARS-CoV-2 and cerebrovascular diseases: does COVID-19 positivity trigger cerebrovascular pathologies?
    Journal of infection in developing countries, 2022, 06-30, Volume: 16, Issue:6

    Topics: Aspirin; Brain Ischemia; Cerebrovascular Disorders; Clopidogrel; COVID-19; Enoxaparin; Humans; Manni

2022
Thromboprophylaxis and clinical outcomes in moderate COVID-19 patients: A comparative study.
    Research in social & administrative pharmacy : RSAP, 2022, Volume: 18, Issue:12

    Topics: Anticoagulants; COVID-19; Enoxaparin; Humans; Rivaroxaban; Venous Thromboembolism

2022
Advanced cell therapy with low tissue factor loaded product NestaCell® does not confer thrombogenic risk for critically ill COVID-19 heparin-treated patients.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 149

    Topics: Cell- and Tissue-Based Therapy; Clinical Trials as Topic; COVID-19; Critical Illness; Enoxaparin; He

2022
Is Rivaroxaban Superior to Enoxaparin for Thromboprophylaxis in Hospitalized Patients of COVID-19?`.
    The Journal of the Association of Physicians of India, 2022, Volume: 70, Issue:9

    Topics: Anticoagulants; COVID-19; Enoxaparin; Humans; Rivaroxaban; Venous Thromboembolism

2022
The Role of Disordered Regions in Orchestrating the Properties of Multidomain Proteins: The SARS-CoV-2 Nucleocapsid Protein and Its Interaction with Enoxaparin.
    Biomolecules, 2022, 09-15, Volume: 12, Issue:9

    Topics: COVID-19; Enoxaparin; Humans; Nucleocapsid Proteins; Polyelectrolytes; RNA; SARS-CoV-2

2022
Central Retinal Vein Occlusion After Discontinuation of Rivaroxaban Therapy in a Young Patient with COVID-19 Pulmonary Embolism: A Case Report.
    The American journal of case reports, 2022, Nov-01, Volume: 23

    Topics: Adult; Angiogenesis Inhibitors; COVID-19; COVID-19 Serotherapy; Enoxaparin; Glucocorticoids; Humans;

2022
Inhalation of Low Molecular Weight Heparins as Prophylaxis against SARS-CoV-2.
    mBio, 2022, 12-20, Volume: 13, Issue:6

    Topics: COVID-19; Enoxaparin; Heparin, Low-Molecular-Weight; Humans; SARS-CoV-2

2022
Clinical evaluation of the safety and efficacy of enoxaparin in patients with COVID-19.
    Blood transfusion = Trasfusione del sangue, 2022, Volume: 20, Issue:6

    Topics: Aged; Anticoagulants; COVID-19; COVID-19 Drug Treatment; Enoxaparin; Hemorrhage; Humans; Male; SARS-

2022
Clinical evaluation of the safety and efficacy of enoxaparin in patients with COVID-19.
    Blood transfusion = Trasfusione del sangue, 2022, Volume: 20, Issue:6

    Topics: Aged; Anticoagulants; COVID-19; COVID-19 Drug Treatment; Enoxaparin; Hemorrhage; Humans; Male; SARS-

2022
Clinical evaluation of the safety and efficacy of enoxaparin in patients with COVID-19.
    Blood transfusion = Trasfusione del sangue, 2022, Volume: 20, Issue:6

    Topics: Aged; Anticoagulants; COVID-19; COVID-19 Drug Treatment; Enoxaparin; Hemorrhage; Humans; Male; SARS-

2022
Clinical evaluation of the safety and efficacy of enoxaparin in patients with COVID-19.
    Blood transfusion = Trasfusione del sangue, 2022, Volume: 20, Issue:6

    Topics: Aged; Anticoagulants; COVID-19; COVID-19 Drug Treatment; Enoxaparin; Hemorrhage; Humans; Male; SARS-

2022
The Effectiveness of the Intermediate and Therapeutic Doses of Enoxaparin in COVID-19 Patients: A Comparative Study of Factor Xa Inhibition.
    Acta haematologica, 2023, Volume: 146, Issue:2

    Topics: Anticoagulants; COVID-19; Cross-Sectional Studies; Enoxaparin; Factor Xa; Factor Xa Inhibitors; Hepa

2023
HIGH HEPARANASE LEVEL IN SURVIVORS OF COVID-19 - INDICATOR OF VASCULAR AND PULMONARY RECOVERY?
    Shock (Augusta, Ga.), 2022, 12-01, Volume: 58, Issue:6

    Topics: Cohort Studies; COVID-19; COVID-19 Drug Treatment; Endothelium, Vascular; Enoxaparin; Glucuronidase;

2022
External validation of the ADA score for predicting thrombosis among acutely ill hospitalized medical patients from the APEX Trial.
    Journal of thrombosis and thrombolysis, 2023, Volume: 55, Issue:2

    Topics: Anticoagulants; COVID-19; Enoxaparin; Humans; Risk Assessment; Risk Factors; Venous Thromboembolism;

2023
Acute Mesenteric Ischemia in COVID-19 While Receiving Prophylactic Enoxaparin.
    Clinical medicine & research, 2022, Volume: 20, Issue:4

    Topics: Anticoagulants; COVID-19; Enoxaparin; Female; Humans; Mesenteric Ischemia; Treatment Outcome

2022
Enoxaparin's potential mechanisms against SARS-CoV-2.
    International journal of surgery (London, England), 2023, 01-01, Volume: 109, Issue:1

    Topics: Anticoagulants; COVID-19; Enoxaparin; Humans; SARS-CoV-2

2023
Clinical experience of prophylactic enoxaparin dosage adjustment guided by AntiXa factor levels in critical care patients with COVID-19-induced pneumonia: observational study.
    Medicina intensiva, 2023, Volume: 47, Issue:8

    Topics: Anticoagulants; COVID-19; Critical Care; Enoxaparin; Heparin, Low-Molecular-Weight; Humans

2023
Pulmonary Embolism and Increased Levels of d-Dimer in Patients with Coronavirus Disease.
    Emerging infectious diseases, 2020, Volume: 26, Issue:8

    Topics: Acute Disease; Aged; Antibodies, Monoclonal, Humanized; Anticoagulants; Betacoronavirus; Biomarkers;

2020
COVID-19 and Acute Pulmonary Embolism in Postpartum Patient.
    Emerging infectious diseases, 2020, Volume: 26, Issue:8

    Topics: Acute Disease; Adult; Anticoagulants; Betacoronavirus; Cesarean Section; Clinical Laboratory Techniq

2020
Systematic assessment of venous thromboembolism in COVID-19 patients receiving thromboprophylaxis: incidence and role of D-dimer as predictive factors.
    Journal of thrombosis and thrombolysis, 2020, Volume: 50, Issue:1

    Topics: Aged; Anticoagulants; Coronavirus Infections; COVID-19; Enoxaparin; Female; Fibrin Fibrinogen Degrad

2020
Is thromboprophylaxis with high-dose enoxaparin really necessary for COVID-19 patients? A new "prudent" randomised clinical trial.
    Blood transfusion = Trasfusione del sangue, 2020, Volume: 18, Issue:3

    Topics: Anticoagulants; Betacoronavirus; Coronavirus Infections; COVID-19; Enoxaparin; Hemostasis; Humans; I

2020
Rebuttal to letter "Is thromboprophylaxis with high-dose enoxaparin really necessary for COVID-19 patients? A new "prudent" randomised clinical trial".
    Blood transfusion = Trasfusione del sangue, 2020, Volume: 18, Issue:3

    Topics: Anticoagulants; Betacoronavirus; Coronavirus Infections; COVID-19; Enoxaparin; Humans; Pandemics; Pn

2020
Cerebral Infarction in an Elderly Patient with Coronavirus Disease.
    Revista da Sociedade Brasileira de Medicina Tropical, 2020, Volume: 53

    Topics: Aged, 80 and over; Anticoagulants; Aspirin; Betacoronavirus; Cerebral Infarction; Coronavirus; Coron

2020
Pulmonary embolism: A complication of COVID 19 infection.
    Thrombosis research, 2020, Volume: 193

    Topics: Adult; Aged; Anticoagulants; Betacoronavirus; Coronavirus Infections; COVID-19; Enoxaparin; Female;

2020
Clinical experience with therapeutic dose of Low-Molecular-Weight Heparin.
    Le infezioni in medicina, 2020, Jun-01, Volume: 28, Issue:suppl 1

    Topics: Aged; Anti-Inflammatory Agents; Anticoagulants; Antihypertensive Agents; Azithromycin; Combined Moda

2020
Heart transplant recipient patient with COVID-19 treated with tocilizumab.
    Transplant infectious disease : an official journal of the Transplantation Society, 2020, Volume: 22, Issue:6

    Topics: Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; Anticoagulants; Cardiomyopathy, Dilated; C

2020
Rhabdomyolysis as an initial presentation in a patient diagnosed with COVID-19.
    BMJ case reports, 2020, Jun-24, Volume: 13, Issue:6

    Topics: Aged; Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; Anticoagulants; Azithromycin; Betaco

2020
Large artery ischemic stroke in severe COVID-19.
    Journal of neurology, 2020, Volume: 267, Issue:12

    Topics: Aged; Brain Ischemia; Cerebral Arteries; Computed Tomography Angiography; Coronavirus Infections; CO

2020
Acute Portal Vein Thrombosis in SARS-CoV-2 Infection: A Case Report.
    The American journal of gastroenterology, 2020, 07-01, Volume: 115, Issue:7

    Topics: Acute Disease; Aged; Anticoagulants; Betacoronavirus; Coronavirus Infections; COVID-19; Enoxaparin;

2020
Incidence of deep vein thrombosis among non-ICU patients hospitalized for COVID-19 despite pharmacological thromboprophylaxis.
    Journal of thrombosis and haemostasis : JTH, 2020, Volume: 18, Issue:9

    Topics: Aged; Aged, 80 and over; COVID-19; Enoxaparin; Female; Fondaparinux; Guidelines as Topic; Hospitaliz

2020
Covid-19: A systemic disease treated with a wide-ranging approach: A case report.
    Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharmacologie clinique, 2020, Jul-03, Volume: 27, Issue:S Pt 1

    Topics: Adrenal Cortex Hormones; Antibodies, Monoclonal, Humanized; Azithromycin; China; Coronavirus Infecti

2020
How haemophilia A impacts severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) treatment: a case report.
    Journal of thrombosis and thrombolysis, 2020, Volume: 50, Issue:4

    Topics: Aged; Betacoronavirus; Blood Coagulation; Coronavirus Infections; COVID-19; Enoxaparin; Female; Fibr

2020
Acute ophthalmic artery occlusion in a COVID-19 patient on apixaban.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2020, Volume: 29, Issue:8

    Topics: Arterial Occlusive Diseases; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatm

2020
Venous thromboembolism in non-critically ill patients with COVID-19 infection.
    Thrombosis research, 2020, Volume: 193

    Topics: Aged; Anticoagulants; Betacoronavirus; Coronavirus Infections; COVID-19; Enoxaparin; Female; Fondapa

2020
VTE in ICU Patients With COVID-19.
    Chest, 2020, Volume: 158, Issue:5

    Topics: Adult; Aged; Anticoagulants; Betacoronavirus; C-Reactive Protein; Computed Tomography Angiography; C

2020
Severe rapidly progressive Guillain-Barré syndrome in the setting of acute COVID-19 disease.
    Journal of neurovirology, 2020, Volume: 26, Issue:5

    Topics: Acute Disease; Aged; Anticoagulants; Betacoronavirus; Coronavirus Infections; COVID-19; Disease Prog

2020
A Case of 45-Year Man Who Succumbed to Coronavirus Disease 2019 (COVID-19).
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2020, Volume: 30, Issue:6

    Topics: Anti-Bacterial Agents; Anticoagulants; Betacoronavirus; Clinical Laboratory Techniques; Coronavirus;

2020
COVID-19 Pulmonary Infection with Pneumothorax in a Young Patient.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2020, Volume: 30, Issue:6

    Topics: Anti-Bacterial Agents; Anticoagulants; Antiviral Agents; Azithromycin; Betacoronavirus; Coronavirus;

2020
A Rare Finding of Upper Limb Deep Venous Thrombosis in a Patient with COVID-19.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2020, Volume: 30, Issue:6

    Topics: Anticoagulants; Arm; Aspirin; Betacoronavirus; Coronavirus Infections; COVID-19; Edema; Enoxaparin;

2020
Priapism in a patient with coronavirus disease 2019 (COVID-19).
    The American journal of emergency medicine, 2021, Volume: 39

    Topics: Anticoagulants; COVID-19; Enoxaparin; Humans; Male; Middle Aged; Priapism; Thrombosis

2021
Saddle pulmonary embolism and thrombus-in-transit straddling the patent foramen ovale 28 days after COVID symptom onset.
    Echocardiography (Mount Kisco, N.Y.), 2020, Volume: 37, Issue:8

    Topics: Aged; Anticoagulants; Computed Tomography Angiography; COVID-19; Dyspnea; Echocardiography; Enoxapar

2020
Use of awake proning to avoid invasive ventilation in a patient with severe COVID-19 pneumonitis.
    BMJ case reports, 2020, Aug-03, Volume: 13, Issue:8

    Topics: Anticoagulants; Betacoronavirus; Chemoprevention; Computed Tomography Angiography; Coronavirus Infec

2020
COVID-19 associated with extensive pulmonary arterial, intracardiac and peripheral arterial thrombosis.
    BMJ case reports, 2020, Aug-03, Volume: 13, Issue:8

    Topics: Anticoagulants; Betacoronavirus; Clinical Deterioration; Computed Tomography Angiography; Coronaviru

2020
COVID-19 patient with immune thrombocytopenic purpura.
    International journal of laboratory hematology, 2020, Volume: 42, Issue:6

    Topics: Aged, 80 and over; Anticoagulants; Autoantibodies; Betacoronavirus; Combined Modality Therapy; Coron

2020
Safety of intermediate dose of low molecular weight heparin in COVID-19 patients.
    Journal of thrombosis and thrombolysis, 2021, Volume: 51, Issue:2

    Topics: Aged; Aged, 80 and over; COVID-19; COVID-19 Drug Treatment; Enoxaparin; Female; Follow-Up Studies; H

2021
COVID-19 in a pediatric patient with Glanzmann thrombasthenia.
    Pediatric blood & cancer, 2020, Volume: 67, Issue:10

    Topics: Adolescent; Amoxicillin; Anti-Bacterial Agents; C-Reactive Protein; Computed Tomography Angiography;

2020
An infection-oriented approach for thoracic endovascular aortic repair in a SARS-CoV-2 positive patient. A case report.
    Annali italiani di chirurgia, 2020, Volume: 91

    Topics: Anesthesia, Local; Antibiotic Prophylaxis; Anticoagulants; Antiviral Agents; Aortic Aneurysm, Thorac

2020
Rotational thromboelastometry in young, previously healthy patients with SARS-Cov2.
    Journal of clinical anesthesia, 2020, Volume: 67

    Topics: Adult; Anticoagulants; Blood Coagulation Disorders; COVID-19; Enoxaparin; Heparin; Humans; Pyrazoles

2020
Inferior mesenteric vein thrombosis and COVID-19.
    Revista da Sociedade Brasileira de Medicina Tropical, 2020, Volume: 53

    Topics: Adult; Analgesics; Anticoagulants; Betacoronavirus; Coronavirus; Coronavirus Infections; COVID-19; E

2020
The hazard of fondaparinux in non-critically ill patients with COVID-19: Retrospective controlled study versus enoxaparin.
    Thrombosis research, 2020, Volume: 196

    Topics: Aged; Aged, 80 and over; Anticoagulants; COVID-19; COVID-19 Drug Treatment; Enoxaparin; Factor Xa In

2020
Clinical Characteristics and Outcomes of Patients Hospitalized for COVID-19 in Africa: Early Insights from the Democratic Republic of the Congo.
    The American journal of tropical medicine and hygiene, 2020, Volume: 103, Issue:6

    Topics: Adolescent; Adult; Asymptomatic Diseases; Azithromycin; Chloroquine; COVID-19; COVID-19 Drug Treatme

2020
Fondaparinux Use in Patients With COVID-19: A Preliminary Multicenter Real-World Experience.
    Journal of cardiovascular pharmacology, 2020, Volume: 76, Issue:4

    Topics: Aged; Anticoagulants; Antithrombins; Coronavirus Infections; COVID-19; Enoxaparin; Factor Xa Inhibit

2020
Thrombo-prophylaxis prevents thrombotic events in home-managed COVID patients. A registry study.
    Minerva medica, 2020, Volume: 111, Issue:4

    Topics: Aged; Anticoagulants; Body Mass Index; Case-Control Studies; COVID-19; Enoxaparin; Female; Heparin,

2020
The impact of protocol-based high-intensity pharmacological thromboprophylaxis on thrombotic events in critically ill COVID-19 patients.
    Anaesthesia, 2021, Volume: 76, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Clinical Protocols; COVID-19; Critical Care; Critica

2021
Venous thromboembolism and COVID-19: a case report and review of the literature.
    Journal of medical case reports, 2020, Oct-15, Volume: 14, Issue:1

    Topics: Aged; Anticoagulants; Betacoronavirus; Computed Tomography Angiography; Coronavirus Infections; COVI

2020
Treatment of COVID-19 induced chilblains with topical nitroglycerin.
    International journal of dermatology, 2020, Volume: 59, Issue:12

    Topics: Administration, Cutaneous; Anticoagulants; Betacoronavirus; Chilblains; Coronavirus Infections; COVI

2020
Effectiveness of lopinavir/ritonavir on COVID-19-related pneumonia in a child with COVID-19-associated Kawasaki disease.
    Cardiology in the young, 2021, Volume: 31, Issue:3

    Topics: Ampicillin; Anti-Bacterial Agents; Anticoagulants; Antiviral Agents; Azithromycin; Child; COVID-19;

2021
Low molecular weight heparin in COVID-19 patients prevents delirium and shortens hospitalization.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2021, Volume: 42, Issue:4

    Topics: Aged; Aged, 80 and over; Anticoagulants; C-Reactive Protein; Cognition Disorders; Cohort Studies; Co

2021
Anticoagulation in COVID-19: Effect of Enoxaparin, Heparin, and Apixaban on Mortality.
    Thrombosis and haemostasis, 2020, Volume: 120, Issue:12

    Topics: Aged; Aged, 80 and over; Anticoagulants; Biomarkers; Blood Coagulation; Cohort Studies; COVID-19; CO

2020
Prognostic factors and predictors of outcome in patients with COVID-19 and related pneumonia: a retrospective cohort study.
    Bioscience reports, 2020, 12-23, Volume: 40, Issue:12

    Topics: Aged; Aged, 80 and over; Anticoagulants; Antiviral Agents; Cardiovascular Diseases; Comorbidity; COV

2020
The unusual experience of managing a severe COVID-19 case at home: what can we do and where do we go?
    BMC infectious diseases, 2020, Nov-19, Volume: 20, Issue:1

    Topics: Adrenal Cortex Hormones; Ambulatory Care; Antiparasitic Agents; Betacoronavirus; Coronavirus Infecti

2020
A case of Evans syndrome secondary to COVID-19.
    Blood transfusion = Trasfusione del sangue, 2021, Volume: 19, Issue:1

    Topics: Adult; Anemia, Hemolytic, Autoimmune; Anticoagulants; COVID-19; Enoxaparin; Humans; Immunoglobulins,

2021
Antiphospholipid antibodies in patients with coronavirus disease 2019 infection hospitalized in conventional unit.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2021, Mar-01, Volume: 32, Issue:2

    Topics: Aged; Aged, 80 and over; Antibodies, Antiphospholipid; Anticoagulants; COVID-19; COVID-19 Drug Treat

2021
Thromboelastography clot strength profiles and effect of systemic anticoagulation in COVID-19 acute respiratory distress syndrome: a prospective, observational study.
    European review for medical and pharmacological sciences, 2020, Volume: 24, Issue:23

    Topics: Aged; Aged, 80 and over; Anticoagulants; Antithrombins; Blood Coagulation Disorders; Blood Coagulati

2020
Superficial Cerebral Venous Thrombosis and Intracerebral Hematoma in a 48-Year-Old Man with SARS-CoV-2 Infection: A Case Report.
    The American journal of case reports, 2021, Jan-01, Volume: 22

    Topics: Anticoagulants; Cerebral Hemorrhage; COVID-19; Enoxaparin; Hematoma; Humans; Intracranial Thrombosis

2021
Increasing dosages of low-molecular-weight heparin in hospitalized patients with Covid-19.
    Internal and emergency medicine, 2021, Volume: 16, Issue:5

    Topics: Aged; Body Mass Index; Cohort Studies; COVID-19; COVID-19 Drug Treatment; Enoxaparin; Female; Hepari

2021
Prolonged treatment of COVID-19 pneumonia with high-flow nasal oxygen: A story of oxygen and resilience.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2020, 10-08, Volume: 110, Issue:12

    Topics: Anti-Bacterial Agents; Anticoagulants; Anxiety; Blood Gas Analysis; Cannula; Citalopram; Counseling;

2020
Efficacy and Safety of D-dimer, Weight, and Renal Function-Adjusted Thromboprophylaxis in Patients with Coronavirus Disease 2019 (COVID-19).
    Seminars in thrombosis and hemostasis, 2021, Volume: 47, Issue:4

    Topics: Aged; Aged, 80 and over; Anticoagulants; Body Weight; C-Reactive Protein; COVID-19; Dose-Response Re

2021
Acute respiratory distress syndrome and COVID-19 in a child with systemic lupus erythematosus.
    Lupus, 2021, Volume: 30, Issue:5

    Topics: Antiviral Agents; Child, Preschool; COVID-19; COVID-19 Drug Treatment; Cytokine Release Syndrome; Cy

2021
American Society of Hematology 2021 guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19.
    Blood advances, 2021, 02-09, Volume: 5, Issue:3

    Topics: Anticoagulants; COVID-19; Enoxaparin; Evidence-Based Medicine; Guidelines as Topic; Humans; SARS-CoV

2021
Early initiation of prophylactic anticoagulation for prevention of coronavirus disease 2019 mortality in patients admitted to hospital in the United States: cohort study.
    BMJ (Clinical research ed.), 2021, 02-11, Volume: 372

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; COVID-19; Enoxaparin; Female; Hemorrhage; Humans; Ma

2021
Fondaparinux and bleeding risk in COVID-19: unsolved question.
    Thrombosis research, 2021, Volume: 200

    Topics: Anticoagulants; COVID-19; Enoxaparin; Fondaparinux; Humans; Retrospective Studies; SARS-CoV-2

2021
Thromboelastography-Guided Management of Anticoagulated COVID-19 Patients to Prevent Hemorrhage.
    Seminars in thrombosis and hemostasis, 2021, Volume: 47, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Algorithms; Anticoagulants; Blood Coagulation Tests; Blood Proteins;

2021
Clinical outcome with different doses of low-molecular-weight heparin in patients hospitalized for COVID-19.
    Journal of thrombosis and thrombolysis, 2021, Volume: 52, Issue:3

    Topics: Aged; Aged, 80 and over; Anticoagulants; COVID-19; Enoxaparin; Female; Hospital Mortality; Hospitali

2021
Healthcare disparities among anticoagulation therapies for severe COVID-19 patients in the multi-site VIRUS registry.
    Journal of medical virology, 2021, Volume: 93, Issue:7

    Topics: Anticoagulants; Blood Coagulation; COVID-19; COVID-19 Drug Treatment; Enoxaparin; Female; Healthcare

2021
The impact of different prophylactic anticoagulation doses on the outcomes of patients with COVID-19.
    Thrombosis research, 2021, Volume: 202

    Topics: Anticoagulants; Blood Coagulation; COVID-19; Enoxaparin; Humans; SARS-CoV-2

2021
Pulmonary embolism in patients with severe COVID-19 treated with intermediate- to full-dose enoxaparin: A retrospective study.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2021, Mar-16, Volume: 91, Issue:3

    Topics: Anticoagulants; COVID-19; Enoxaparin; Humans; Pulmonary Embolism; Retrospective Studies; SARS-CoV-2;

2021
Ovarian vein thrombosis after coronavirus disease (COVID-19) mimicking acute abdomen: two case reports.
    Journal of thrombosis and thrombolysis, 2021, Volume: 52, Issue:2

    Topics: Abdomen, Acute; Adult; Anticoagulants; COVID-19; Diagnosis, Differential; Enoxaparin; Female; Fibrin

2021
Use of repurposed and adjuvant drugs in hospital patients with covid-19: multinational network cohort study.
    BMJ (Clinical research ed.), 2021, 05-11, Volume: 373

    Topics: Administrative Claims, Healthcare; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and ov

2021
Massive Pulmonary Embolism in an Adolescent With Multisystem Inflammatory Syndrome Due to COVID-19.
    Clinical pediatrics, 2021, Volume: 60, Issue:8

    Topics: Adolescent; Computed Tomography Angiography; COVID-19; Enoxaparin; Female; Fibrinolytic Agents; Huma

2021
Incidence of deep vein thrombosis through an ultrasound surveillance protocol in patients with COVID-19 pneumonia in non-ICU setting: A multicenter prospective study.
    PloS one, 2021, Volume: 16, Issue:5

    Topics: Aged; Aged, 80 and over; Anticoagulants; COVID-19; Enoxaparin; Female; Fondaparinux; Humans; Inciden

2021
DIC-Like Syndrome Following Administration of ChAdOx1 nCov-19 Vaccination.
    Viruses, 2021, 06-01, Volume: 13, Issue:6

    Topics: ChAdOx1 nCoV-19; Clinical Laboratory Techniques; COVID-19; COVID-19 Vaccines; Dexamethasone; Dissemi

2021
High-Dose Prophylactic Anticoagulation in Severe COVID-19 Pneumonia.
    Chest, 2021, Volume: 160, Issue:1

    Topics: Anticoagulants; Blood Coagulation; COVID-19; Enoxaparin; Humans; SARS-CoV-2

2021
Pharmacokinetics of enoxaparin in COVID-19 critically ill patients.
    Thrombosis research, 2021, Volume: 205

    Topics: Anticoagulants; COVID-19; Critical Illness; Enoxaparin; Humans; Retrospective Studies; SARS-CoV-2

2021
Acetylsalicylic Acid Compared with Enoxaparin for the Prevention of Thrombosis and Mechanical Ventilation in COVID-19 Patients: A Retrospective Cohort Study.
    Clinical drug investigation, 2021, Volume: 41, Issue:8

    Topics: Anticoagulants; Aspirin; COVID-19; Enoxaparin; Humans; Respiration, Artificial; Retrospective Studie

2021
COVID-19 and Hepatic Artery Thrombosis: A Case Report.
    The American journal of case reports, 2021, Aug-01, Volume: 22

    Topics: COVID-19; Enoxaparin; Female; Hepatic Artery; Humans; Middle Aged; SARS-CoV-2; Thrombosis

2021
First case report of a successfully managed severe COVID-19 infection in Malawi.
    Malawi medical journal : the journal of Medical Association of Malawi, 2020, Volume: 32, Issue:4

    Topics: Administration, Intravenous; Anti-Bacterial Agents; Anticoagulants; Ceftriaxone; COVID-19; COVID-19

2020
Severe COVID-19 infection associated with endothelial activation.
    Thrombosis research, 2020, Volume: 190

    Topics: Aged; Antibodies, Antiphospholipid; Anticoagulants; Betacoronavirus; Blood Coagulation; Coronavirus

2020
Severe COVID-19 infection associated with endothelial activation.
    Thrombosis research, 2020, Volume: 190

    Topics: Aged; Antibodies, Antiphospholipid; Anticoagulants; Betacoronavirus; Blood Coagulation; Coronavirus

2020
Severe COVID-19 infection associated with endothelial activation.
    Thrombosis research, 2020, Volume: 190

    Topics: Aged; Antibodies, Antiphospholipid; Anticoagulants; Betacoronavirus; Blood Coagulation; Coronavirus

2020
Severe COVID-19 infection associated with endothelial activation.
    Thrombosis research, 2020, Volume: 190

    Topics: Aged; Antibodies, Antiphospholipid; Anticoagulants; Betacoronavirus; Blood Coagulation; Coronavirus

2020
Image-proven thromboembolism in patients with severe COVID-19 in a tertiary critical care unit in the United Kingdom.
    Thrombosis research, 2020, Volume: 193

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Betacoronavirus; Coronavirus Infections; COVID-19; C

2020
A single-centre, prospective cohort study of COVID-19 patients admitted to ICU for mechanical ventilatory support.
    Acta anaesthesiologica Scandinavica, 2021, Volume: 65, Issue:3

    Topics: Anticoagulants; Cohort Studies; COVID-19; COVID-19 Drug Treatment; Critical Care; Dalteparin; Female

2021
Dosing of thromboprophylaxis and mortality in critically ill COVID-19 patients.
    Critical care (London, England), 2020, 11-23, Volume: 24, Issue:1

    Topics: Aged; Anticoagulants; APACHE; COVID-19; Critical Illness; Dalteparin; Female; Humans; Intensive Care

2020