dactinomycin and Osteogenic Sarcoma

dactinomycin has been researched along with Osteogenic Sarcoma in 138 studies

Research

Studies (138)

TimeframeStudies, this research(%)All Research%
pre-199079 (57.25)18.7374
1990's41 (29.71)18.2507
2000's12 (8.70)29.6817
2010's5 (3.62)24.3611
2020's1 (0.72)2.80

Authors

AuthorsStudies
Csikos, C; Hegedűs, C; Kiss, A; Polgár, Z; Regdon, Z; Virág, L1
Burchill, SA; Jabri, S; Roundhill, EA1
Cai, HQ; Li, YC; Wang, ZG; Xu, YL; Yang, J1
Choi, YJ; Lee, HW; Lee, YS; Seo, SW; Shim, da M1
Cho, Y; Choi, Y; Chung, SH; Jung, GH; Kim, JD; Kim, JY1
Bao, CF; Li, XH; Yang, LM1
Ayala, AG; Devidas, M; Gebhardt, MC; Goorin, AM; Grier, HE; Harris, MB; Helman, LJ; Link, MP; Schwartzentruber, DJ1
D'ANGIO, GJ1
ROCHLIN, DB1
NAHUM, AM1
Goto, T; Hozumi, T; Kobayashi, H; Kondo, T; Kosaku, H1
Goi, K; Hamada, Y; Inukai, T; Nakazawa, S; Sato, H; Sugita, K; Tezuka, T; Uno, K1
Bashir, H; Crom, D; Hudson, MM; Jones, D; Metzger, M; Mulcahey, J1
Bacci, G; Balladelli, A; Bertoni, F; Briccoli, A; Ferrari, S; Forni, C; Longhi, A; Mercuri, M; Picci, P; Serra, M1
Barbieri, S; Derenzini, M; Donati, G; Govoni, M; Mazzini, G; Montanaro, L; Nardi-Pantoli, A; Treré, D; Vici, M1
Goto, T; Hozumi, T; Kondo, T; Nakada, I; Okuma, T1
Blondet, R; Bouffet, E; Brunat-Mentigny, M; Chauvot, P; Moyen, B; Philip, T1
Abeling, NG; Behrendt, H; Cranendonk, E; van Gennip, AH1
Jürgens, H; Rosen, G1
Cacavio, A; Caparros, B; Huvos, AG; Kosloff, C; Lane, JM; Marcove, RC; Mehta, B; Nirenberg, A; Rosen, G; Urban, C1
Beck, J; Beck, W; Beron, G; Brandeis, W; Ebell, W; Erttmann, R; Göbel, U; Havers, W; Henze, G; Hinderfield, L; Höcker, P; Jobke, A; Jürgens, H; Kabisch, H; Kotz, R; Landbeck, G; Preusser, P; Prindull, G; Ramach, W; Ritter, J; Salzer-Kuntschik, M; Sekera, J; Treuner, J; Winkler, K; Wüst, G1
Souhami, RL1
Beck, J; Beck, W; Beron, G; Brandeis, W; Ebell, W; Erttmann, R; Göbel, U; Kotz, R; Salzer-Kuntschik, M; Winkler, K1
Cacavio, A; Caparros, B; Groshen, S; Huvos, AG; Lane, JM; Marcove, RC; Nirenberg, A; Rosen, G1
Pan, LC; Price, PA1
Kaye, SB; Ryman, BE1
Boden, JA; Kaye, SB; Ryman, BE1
Corbett, TH; Griswold, DP; Laster, WR; Schabel, FM; Skipper, HE; Trader, MW1
Carpentier, AF; Chantelard, JV; Henin, D; Poisson, M1
Link, MP1
Bielack, SS; Delling, G; Jürgens, H; Kotz, R; Salzer-Kuntschik, M; Winkler, K1
Krailo, M; Miser, JS1
Avella, M; Bacci, G; Casadei, R; Cazzola, A; Ferrari, S; Lari, S; Monti, C; Picci, P; Prever, BA; Ruggieri, P1
Heller, G; Meyers, PA; Vlamis, V1
Delepine, G; Delepine, N; Desbois, JC1
Contesso, G; Edeline, V; Kalifa, C; Lemerle, J; Razafindrakoto, H; Valteau, D; Vanel, D; Vassal, G1
Ekert, H; Tiedemann, K1
Göeken, LN; Kamps, WA; Molenaar, WM; Postma, A; Schraffordt Koops, H; Veth, RP1
Bloem, JL; Doornbos, J; Hermans, J; Holscher, HC; Nooy, MA; van der Woude, HJ1
Bos, G; Brown, D; Fletcher, WS; Lebredo, L; Moseley, HS; Small, K; Woltering, EA1
Goorin, A; Hallowell, JA; Kharasch, VS; Lipsitz, S; Santis, W1
Baum, ES; Betcher, DL; Ettinger, LJ; Huvos, AG; Kisker, CT; Krailo, MD; Makley, JT; Miser, JS; Nachman, JB; Provisor, AJ; Yunis, EJ1
Denhardt, DT; Kageyama, R; Matsue, M; Noda, M1
Epstein, JI; North, RB; Sipos, EP; Tamargo, RJ1
Kwon, HJ; Sawamura, M; Schreiber, SL; Shimada, J1
Drüeke, TB; Yaghoobian, J1
Busch, H; Cai, ZJ; Henning, D; Perlaky, L; Valdez, BC1
Casper, E; Gorlick, R; Healey, JH; Heller, G; Huvos, AG; Lane, J; Meyers, PA1
Egawa, K; Kunimoto, S; Nishigori, H; Nose, K; Takeuchi, T1
La Thangue, NB; Lee, CW1
Haneji, T; Kido, H; Kobayashi, S; Morimoto, H; Morimoto, Y; Ohba, T1
Ben Abdallah, M; Ben Ayed, F; Ben Ghachem, M; Ben Hamida, H; Ben Hassine, H; Ben Romdhane, K; Boussen, H; Daldoul, O; Douik, M; Gamoudi, A; Karray, S; Khalfallah, S; Mezlini, A; Mezzi, F; Saadi, A1
Liu, C; Watson, CE; Werth, VP; Williams, KJ; Zhang, W1
Gebski, V; Machin, D; Tai, BC; White, I1
Arbizu, J; López de Mesa, R; Narbona, J; Sánchez-Carpintero, R; Sierrasesúmaga, L1
Albrecht, RM; Bertics, PJ; Mellon, WS; Mosavin, R; Rivera-Bermúdez, MA1
Ise, T1
Caparros, B; Gutierrez, M; Mosende, C; Rosen, G1
Laster, WR; Rose, WC; Schabel, FM; Trader, MW1
Rosen, G3
Blasková, L; Krizan, I; Krizan, Z; Látal, J; Majeský, B; Makai, F1
Evans, AE1
Ahmann, DL; Bisel, HF; Creagan, ET; Eagan, RT; Edmonson, JH; Hahn, RG1
Afridi, MA; Douglass, H; Friedman, M; Wallace, JH1
Cassady, RJ; Filler, RM; Jaffe, N; Murray, J; Traggis, D; Watts, H; Weichselbaum, R; Weinstein, H1
Jaffe, N1
Plager, C; Sinkovics, JG1
Meuret, G1
Chabora, BM; Rosen, G; Tefft, M1
Brown, BL; Lazarus, H; Modest, EJ; Sengupta, SK; Tinter, SK1
Bacci, G; Pagani, PA1
Galbraith, WM; Mellett, LB1
Cangir, A; Sullivan, MP; Sutow, WW; Wilbur, JR1
Applewhite, A; Healey, J; Heller, G; Huvos, A; Lane, J; Marcove, R; Meyers, PA; Rosen, G; Vlamis, V1
Black, T; Estrada-Aguilar, J; Greenberg, H; Hvizdala, E; Morse, S; Schroer, K; Walling, A1
Bunning, RA; Fawthrop, FW; Oyajobi, BO; Russell, RG1
Blomqvist, C; Elomaa, I; Holmström, T; Karaharju, E; Laasonen, E; Ryöppy, S; Siimes, MA1
Bröcheler, J; Mertens, R; Niedeggen, A; Röther, J; Weis, J1
Eldridge, RM; Fleming, RA; Johnson, CE; Stewart, CF1
Buchanan, GR; Pappo, A; Sanders, JM; Schneider, NR1
Glasser, DB; Lane, JM1
Alvegård, TA; Elomaa, I; Holmström, T; Saeter, G; Solheim, OP; Stenwig, AE1
Abuchaibe, O; Antillon, F; Azinovic, I; Calvo, FA; Cañadell, J; Ortiz de Urbina, D; Santos, M; Sierrasesúmaga, L1
Jurczyk-Procyk, S; Perek, D1
Allan, EH; Fukumoto, S; Gelehrter, TD; Martin, TJ; Zeheb, R1
Flanigan, P; Freshney, RI; Hamilton, TG; Kaye, SB; Merry, S1
Allan, EH; Fukumoto, S; Gelehrter, TD; Heaton, JH; Martin, TJ; Yee, JA; Zeheb, R1
Willnow, U1
Aloe, L; Carlini, S; Cavaliere, F; Cavaliere, R; Cavallero, L; Di Filippo, F; Giannarelli, D; Moscarelli, F1
Binderman, I; Kaye, AM; Mayer, H; Schlüter, KD; Sömjen, D; Wingender, E1
Green, E; Heath, D; Todd, B1
Delling, G; Knop, J; Montz, R; Stritzke, P; Winkler, K1
Eschenbach, C; Maroske, D; Winkler, K1
Delling, G; Hajek, P; Kotz, R; Kumpan, W; Lechner, G; Salzer-Kuntschik, M; Sekera, J; Wittich, GR1
Huvos, AG; Marcove, R; Nirenberg, A; Rosen, G1
Epelman, S; Jaffe, N; Pratt, CB1
Dawson, P; Dean, L; Nachman, J; Shermeta, D; Simon, MA; Vogelzang, NJ1
Bauters, F; Fenaux, P; Jouet, JP; Lai, JL; Lepelley, P1
Berger, J; Beron, G; Delling, G; Gerein, V; Heise, U; Jürgens, H; Kabisch, H; Purfürst, C; Ritter, J; Winkler, K1
Bachelot, C; Boitetot, A; Brunat-Mentigny, M; Demaille, MC; Gentet, JC; Noir, P; Olive, D; Quitana, E; Roche, H; Thyss, JP1
Contesso, G; Dubousset, J; Kalifa, C; Lumbroso, J; Mlika, N; Vanel, D1
Kettler, AH; Levy, ML; Scallan, PJ; Tschen, JA1
Bielack, S; Delling, G; Knop, J; Winkler, K1
Price, PA; Theofan, G1
Beppu, Y; Chuman, H; Fukuma, H1
Baranzelli, MC; Bouretz, JC; Demaille, MC; Dusol, F; Gosselin, P1
Avella, M; Bacchini, P; Bacci, G; Bertoni, F; Campanacci, M; Dallari, D; Fontana, M; Mercuri, M; Pignatti, G1
Heikkinen, E; Lanning, M; Lanning, P1
Birkenhäger, JC; Pols, HA; Schilte, JP; Visser, TJ1
Birkenhäger, JC; Pols, HA; Schilte, JP; van Leeuwen, JP; Visser, TJ1
Avioli, LV; Birge, SJ; Kim, YS; Miller, R1
Kamel, HM; Merry, S; Toner, PG1
Butler, WT; Noda, M; Prince, CW; Rodan, GA; Yoon, K1
Adachi, N; Fukuma, H; Hanada, M; Ohira, M; Takayama, J1
D'Souza, SM; Mundy, GR; Pfeilschifter, J1
Butler, WT; Prince, CW1
Deftos, JL; Manolagas, SC; Price, PA; Spiess, YH1
Billiau, A; Cayphas, S; Opdenakker, G; Van Damme, J; Van Snick, J1
Majeska, RJ; Nair, BC; Rodan, GA1
Atherton, E; Meienhofer, J; Patel, RP; Sano, Y1
Ahmann, DL; Cupps, RE; Soule, EH1
Freeman, JE; Malpas, JS1
Balconi, G; Morasca, L1
Ansfield, FJ; Davis, HL; Jaeschke, W; Ramirez, G; Wiley, AL; Wirtanen, GW; Wu, JP1
Freckman, HA1
Plüss, HJ1
Fernandez, CH; Gottlieb, JA1
Brown, BL; D'Angio, GJ; Farber, S; Maddock, CL1
Brown, BL; D'Angio, GJ; Maddock, CL; Tefft, M1
Philips, FS; Schwartz, HS; Sodergren, JE; Sternberg, SS1
Schwartz, HS; Sodergren, JE1
Ambaye, RY; Schwartz, HS; Sodergren, JE1
Blodi, FC1
Friedman, RM; Stern, R1
Morasca, L; Roy-Camille, R1
Meienhofer, J; Patel, RP1

Reviews

7 review(s) available for dactinomycin and Osteogenic Sarcoma

ArticleYear
[Soft tissue sarcoma: postoperative chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Combined Modality Therapy; Cyclophosphamide; Dacarbazine; Dactinomycin; Doxorubicin; Drug Administration Schedule; Humans; Ifosfamide; Melphalan; Mesna; Methotrexate; Osteosarcoma; Rhabdomyosarcoma; Sarcoma; Sarcoma, Ewing; Soft Tissue Neoplasms; Vincristine

2004
Treatment of osteosarcoma: experience of the Cooperative Osteosarcoma Study Group (COSS).
    Cancer treatment and research, 1993, Volume: 62

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Clinical Protocols; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Germany; Humans; Ifosfamide; Immunologic Factors; Interferon-beta; Methotrexate; Multicenter Studies as Topic; Osteosarcoma; Prognosis; Randomized Controlled Trials as Topic; Treatment Outcome; Vincristine

1993
Osteosarcoma of the extremities: chemotherapy experience at Memorial Sloan-Kettering.
    Cancer treatment and research, 1993, Volume: 62

    Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Male; Methotrexate; New York; Osteosarcoma; Prognosis; Proportional Hazards Models; Racial Groups; Retrospective Studies; Risk; Survival Rate; Treatment Outcome

1993
The success and failure of multimodal therapy for cancer in children.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Adolescent; Age Factors; Child; Dactinomycin; Humans; Lymph Node Excision; Male; Methotrexate; Neoplasm Metastasis; Neoplasms; Neuroblastoma; Osteosarcoma; Prognosis; Retinoblastoma; Rhabdomyosarcoma; Sarcoma; Testicular Neoplasms; Vincristine; Wilms Tumor

1975
[Therapy of sarcomas].
    Deutsche medizinische Wochenschrift (1946), 1978, Feb-17, Volume: 103, Issue:7

    Topics: Adolescent; Adult; Bone Neoplasms; Child; Cyclophosphamide; Dacarbazine; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Humans; Methotrexate; Middle Aged; Osteosarcoma; Remission, Spontaneous; Rhabdomyosarcoma; Sarcoma; Sarcoma, Ewing; Soft Tissue Neoplasms; Vincristine

1978
Secondary myelodysplastic syndrome complicating therapy for osteogenic sarcoma.
    Cancer, 1991, Sep-15, Volume: 68, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Cisplatin; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Methotrexate; Myelodysplastic Syndromes; Osteosarcoma

1991
Proceedings: Recent progress in the chemotherapy of primary tumors of bone.
    Proceedings. National Cancer Conference, 1972, Volume: 7

    Topics: Antineoplastic Agents; Bone Neoplasms; Cyclophosphamide; Dactinomycin; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Humans; Osteosarcoma; Sarcoma, Ewing; Vincristine

1972

Trials

19 trial(s) available for dactinomycin and Osteogenic Sarcoma

ArticleYear
Presurgical chemotherapy compared with immediate surgery and adjuvant chemotherapy for nonmetastatic osteosarcoma: Pediatric Oncology Group Study POG-8651.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Apr-15, Volume: 21, Issue:8

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Cyclophosphamide; Dactinomycin; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Female; Humans; Leucovorin; Male; Methotrexate; Neoadjuvant Therapy; Osteosarcoma; Survival Analysis; Treatment Outcome

2003
Adjuvant chemotherapy in osteosarcoma - effects of cisplatinum, BCD, and fibroblast interferon in sequential combination with HD-MTX and adriamycin. Preliminary results of the COSS 80 study.
    Journal of cancer research and clinical oncology, 1983, Volume: 106 Suppl

    Topics: Adult; Antineoplastic Agents; Bone Neoplasms; Cisplatin; Clinical Trials as Topic; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Humans; Interferons; Methotrexate; Osteosarcoma; Preoperative Care; Random Allocation

1983
Neoadjuvant chemotherapy for osteogenic sarcoma: results of a Cooperative German/Austrian study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:6

    Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Female; Humans; Interferon Type I; Male; Methotrexate; Osteosarcoma; Prognosis

1984
Primary osteogenic sarcoma of the femur: a model for the use of preoperative chemotherapy in high risk malignant tumors.
    Cancer investigation, 1984, Volume: 2, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Child, Preschool; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Femoral Neoplasms; Humans; Leucovorin; Male; Methotrexate; Osteosarcoma; Premedication; Prognosis

1984
The multi-institutional osteosarcoma study: an update.
    Cancer treatment and research, 1993, Volume: 62

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Clinical Protocols; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Humans; Leucovorin; Life Tables; Methotrexate; Osteosarcoma; Survival Rate; Treatment Outcome; United States

1993
Osteosarcoma in adolescents and young adults: new developments and controversies. The Childrens Cancer Group (CCG) studies.
    Cancer treatment and research, 1993, Volume: 62

    Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Humans; Leucovorin; Methotrexate; Osteosarcoma; Survival Rate; Treatment Outcome; United States; Vincristine

1993
Neoadjuvant chemotherapy for nonmetastatic osteosarcoma of the extremities: the recent experience at the Rizzoli Institute.
    Cancer treatment and research, 1993, Volume: 62

    Topics: Actuarial Analysis; Adolescent; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Clinical Protocols; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Extremities; Female; Humans; Italy; Male; Methotrexate; Necrosis; Osteosarcoma; Prognosis; Salvage Therapy; Survival Analysis

1993
Chemotherapy in osteogenic sarcoma: the experience of the Pediatric Department of the Gustave Roussy Institute.
    Cancer treatment and research, 1993, Volume: 62

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Feasibility Studies; Female; France; Humans; Ifosfamide; Leucovorin; Male; Methotrexate; Osteosarcoma; Survival Rate; Treatment Outcome; Vincristine

1993
Osteosarcoma of the limb: an institutional report of 10 years experience with neoadjuvant chemotherapy and delayed surgery.
    Cancer treatment and research, 1993, Volume: 62

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Humans; Leucovorin; Life Tables; Methotrexate; Osteosarcoma; Treatment Outcome; Vincristine

1993
Treatment of nonmetastatic osteosarcoma of the extremity with preoperative and postoperative chemotherapy: a report from the Children's Cancer Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cyclophosphamide; Dactinomycin; Disease-Free Survival; Extremities; Humans; Methotrexate; Osteosarcoma; Vincristine

1997
Intensification of preoperative chemotherapy for osteogenic sarcoma: results of the Memorial Sloan-Kettering (T12) protocol.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Cyclophosphamide; Dactinomycin; Disease-Free Survival; Doxorubicin; Female; Humans; Male; Methotrexate; Necrosis; Osteosarcoma; Time Factors; Treatment Outcome

1998
Competing risks analysis of patients with osteosarcoma: a comparison of four different approaches.
    Statistics in medicine, 2001, Mar-15, Volume: 20, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Cisplatin; Cyclophosphamide; Dactinomycin; Disease-Free Survival; Doxorubicin; Female; Humans; Lung Neoplasms; Male; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Proportional Hazards Models; Risk Assessment

2001
A comparative clinical trial evaluating the combination of adriamycin, DTIC, and vincristine, the combination of actinomycin D, cyclophosphamide, and vincristine, and a single agent, methyl-CCNU, in advanced sarcomas.
    Cancer treatment reports, 1976, Volume: 60, Issue:9

    Topics: Adult; Cyclophosphamide; Dacarbazine; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Female; Fibrosarcoma; Hemangiopericytoma; Histiocytoma, Benign Fibrous; Humans; Leiomyosarcoma; Lomustine; Male; Mesothelioma; Neurofibroma; Nitrosourea Compounds; Osteosarcoma; Rhabdomyosarcoma; Sarcoma; Triazenes; Vincristine

1976
Study of adjuvant chemotherapy in osteogenic sarcoma.
    Journal of clinical pharmacology, 1975, Volume: 15, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Agents; Child; Clinical Trials as Topic; Cyclophosphamide; Dactinomycin; Drug Therapy, Combination; Female; Humans; Male; Neoplasm Metastasis; Osteosarcoma; Vincristine

1975
Intraoperative radiotherapy in the multidisciplinary treatment of bone sarcomas in children and adolescents.
    Medical and pediatric oncology, 1991, Volume: 19, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Follow-Up Studies; Humans; Intraoperative Period; Male; Methotrexate; Osteosarcoma; Prospective Studies; Recurrence; Remission Induction; Sarcoma, Ewing; Vincristine

1991
[Alternative chemotherapy of malignant bone neoplasms in children].
    Problemy medycyny wieku rozwojowego, 1990, Volume: 16

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Humans; Leucovorin; Methotrexate; Organoplatinum Compounds; Osteosarcoma; Sarcoma, Ewing; Vincristine

1990
Bleomycin, cyclophosphamide, and dactinomycin in metastatic osteosarcoma: lack of tumor regression in previously treated patients.
    Cancer treatment reports, 1987, Volume: 71, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Clinical Trials as Topic; Cyclophosphamide; Dactinomycin; Female; Humans; Male; Neoplasm Metastasis; Osteosarcoma

1987
Neoadjuvant chemotherapy of osteosarcoma: results of a randomized cooperative trial (COSS-82) with salvage chemotherapy based on histological tumor response.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:2

    Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Male; Methotrexate; Osteosarcoma; Postoperative Period; Preoperative Care; Prognosis; Random Allocation

1988
[Scintigraphic follow-up of osteosarcoma during neoadjuvant chemotherapy. Results of the cooperative osteosarcoma study of the Society for Pediatric Oncology].
    Nuklearmedizin. Nuclear medicine, 1988, Volume: 27, Issue:6

    Topics: Adolescent; Adult; Altretamine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Follow-Up Studies; Humans; Methotrexate; Multicenter Studies as Topic; Osteosarcoma; Radionuclide Imaging; Technetium Tc 99m Medronate

1988

Other Studies

112 other study(ies) available for dactinomycin and Osteogenic Sarcoma

ArticleYear
NMNAT1 Is a Survival Factor in Actinomycin D-Induced Osteosarcoma Cell Death.
    International journal of molecular sciences, 2021, Aug-18, Volume: 22, Issue:16

    Topics: Antibiotics, Antineoplastic; Apoptosis; Biomarkers, Tumor; Bone Neoplasms; Cell Proliferation; Dactinomycin; Gene Expression Regulation, Neoplastic; Humans; Nicotinamide-Nucleotide Adenylyltransferase; Osteosarcoma; Poly (ADP-Ribose) Polymerase-1; Sirtuin 1; Tumor Cells, Cultured

2021
ABCG1 and Pgp identify drug resistant, self-renewing osteosarcoma cells.
    Cancer letters, 2019, 07-01, Volume: 453

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; Bone Neoplasms; Cell Growth Processes; Cell Line, Tumor; Dactinomycin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; HEK293 Cells; Hep G2 Cells; Humans; MCF-7 Cells; Neoplastic Stem Cells; Osteosarcoma; RNA, Messenger; Vincristine

2019
Effect of variation of ABCB1 and ABCC3 genotypes on the survival of bone tumor cases after chemotherapy.
    Asian Pacific journal of cancer prevention : APJCP, 2013, Volume: 14, Issue:8

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Dactinomycin; Doxorubicin; Female; Follow-Up Studies; Genotype; Humans; Male; Methotrexate; Middle Aged; Multidrug Resistance-Associated Proteins; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Osteosarcoma; Polymorphism, Single Nucleotide; Prognosis; Survival Rate; Vincristine; Young Adult

2013
RRP12 is a crucial nucleolar protein that regulates p53 activity in osteosarcoma cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:4

    Topics: Apoptosis; Cell Line, Tumor; Cell Nucleolus; Cell Survival; Dactinomycin; DNA Damage; Doxorubicin; Humans; Nuclear Proteins; Osteosarcoma; Tumor Suppressor Protein p53

2016
Long-term survivals of stage IIb osteosarcoma: a 20-year experience in a single institution.
    Clinics in orthopedic surgery, 2011, Volume: 3, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cyclophosphamide; Dactinomycin; Disease-Free Survival; Doxorubicin; Female; Follow-Up Studies; Humans; Infant; Kaplan-Meier Estimate; Leucovorin; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Osteosarcoma; Survival Rate; Vincristine; Young Adult

2011
Glutathione S-transferase P1 and DNA polymorphisms influence response to chemotherapy and prognosis of bone tumors.
    Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:11

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Cyclophosphamide; Dactinomycin; DNA-Binding Proteins; DNA, Neoplasm; Doxorubicin; Endonucleases; Female; Glutathione S-Transferase pi; Humans; Male; Methotrexate; Neoplasm Staging; Osteosarcoma; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Prognosis; Survival Rate; Vincristine; Xeroderma Pigmentosum Group D Protein; Young Adult

2012
Laboratory and clinical observations with combined actinomycin D and x-radiation.
    Laval medical, 1963, Volume: 34

    Topics: Dactinomycin; Humans; Neoplasms; Osteosarcoma; Radiation Effects; Radiotherapy; Sarcoma; Wilms Tumor; X-Rays

1963
THE THERAPY OF SARCOMAS BY ISOLATION PERFUSION.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Aorta; Aorta, Abdominal; Bone Neoplasms; Carotid Arteries; Chemotherapy, Cancer, Regional Perfusion; Chondrosarcoma; Dactinomycin; Dogs; Fibrosarcoma; Iliac Artery; Iliac Vein; Leiomyosarcoma; Liposarcoma; Lymphoma, Non-Hodgkin; Melphalan; Mesothelioma; Neoplasms; Neuroblastoma; Osteosarcoma; Rhabdomyosarcoma; Sarcoma; Sarcoma, Kaposi; Subclavian Artery; Vena Cava, Inferior

1964
OSTEOGENIC SARCOMA OF THE MANDIBLE. REPORT OF CASE TREATED BY RADIATION AND CHEMOTHERAPY.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1964, Volume: 80

    Topics: Bone Neoplasms; Cobalt Isotopes; Dactinomycin; Drug Therapy; Humans; Mandible; Mandibular Neoplasms; Melphalan; Methotrexate; Neoplasms; Osteomyelitis; Osteosarcoma; Pathology; Radiography; Radium; Sarcoma

1964
A successful case of allogeneic bone marrow transplantation for osteosarcoma with multiple metastases of lung and bone.
    Bone marrow transplantation, 2006, Volume: 37, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Transplantation; Child; Cyclophosphamide; Dactinomycin; Doxorubicin; Femoral Neoplasms; Humans; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Remission Induction; Transplantation, Homologous; Treatment Outcome

2006
Cisplatin-induced hypomagnesemia and cardiac dysrhythmia.
    Pediatric blood & cancer, 2007, Volume: 49, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Cisplatin; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Gastroenteritis; Heart Arrest; Humans; Magnesium; Methotrexate; Osteosarcoma; Water-Electrolyte Imbalance

2007
Local recurrence and local control of non-metastatic osteosarcoma of the extremities: a 27-year experience in a single institution.
    Journal of surgical oncology, 2007, Aug-01, Volume: 96, Issue:2

    Topics: Adolescent; Adult; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Contraindications; Cyclophosphamide; Dactinomycin; Drug Administration Schedule; Extremities; Female; Humans; Limb Salvage; Male; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Treatment Outcome

2007
Different effects of ribosome biogenesis inhibition on cell proliferation in retinoblastoma protein- and p53-deficient and proficient human osteosarcoma cell lines.
    Cell proliferation, 2007, Volume: 40, Issue:4

    Topics: Bone Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Dactinomycin; Humans; Nucleic Acid Synthesis Inhibitors; Osteosarcoma; Retinoblastoma Protein; Ribosomes; RNA Interference; RNA, Ribosomal; Tumor Suppressor Protein p53

2007
[Preoperative adjuvant therapy for primary malignant bone tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Administration Schedule; Humans; Ifosfamide; Neoadjuvant Therapy; Neoplasm Metastasis; Osteosarcoma; Prognosis; Sarcoma, Ewing; Soft Tissue Neoplasms; Vincristine

2007
[Initial chemotherapy and conservative surgery in the current treatment of osteosarcoma. Apropos of 24 cases].
    Annales de pediatrie, 1984, Oct-15, Volume: 31, Issue:9

    Topics: Adolescent; Adult; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Follow-Up Studies; Humans; Leucovorin; Male; Methods; Methotrexate; Osteosarcoma; Vincristine

1984
Numerical changes in the various peripheral white blood cells in children as a result of antineoplastic therapy.
    Acta haematologica, 1984, Volume: 72, Issue:5

    Topics: Antineoplastic Agents; Basophils; Child; Cyclophosphamide; Dactinomycin; Doxorubicin; Eosinophils; Hodgkin Disease; Humans; Leukocyte Count; Leukocytes; Lymphocytes; Methotrexate; Monocytes; Neuroblastoma; Osteosarcoma; Rhabdomyosarcoma; Sarcoma, Ewing; Time Factors; Vincristine; Wilms Tumor

1984
[Combination chemotherapy in osteogenic sarcoma: the Memorial Sloan-Kettering cancer center experience (author's transl)].
    Klinische Padiatrie, 1980, Volume: 192, Issue:2

    Topics: Adolescent; Adult; Bleomycin; Child; Cisplatin; Cyclophosphamide; Dactinomycin; Drug Therapy, Combination; Female; Humans; Lung Neoplasms; Male; Methotrexate; Osteosarcoma; Preoperative Care

1980
Preoperative chemotherapy for osteogenic sarcoma: selection of postoperative adjuvant chemotherapy based on the response of the primary tumor to preoperative chemotherapy.
    Cancer, 1982, Mar-15, Volume: 49, Issue:6

    Topics: Antineoplastic Agents; Bleomycin; Bone Neoplasms; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Humans; Leucovorin; Methotrexate; Osteosarcoma; Prognosis; Time Factors

1982
What has adjuvant chemotherapy of osteosarcoma achieved? Discussion paper.
    Journal of the Royal Society of Medicine, 1983, Volume: 76, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Administration Schedule; Humans; Methotrexate; Osteosarcoma

1983
The effect of transcriptional inhibitors on the bone gamma-carboxyglutamic acid protein response to 1,25-dihydroxyvitamin D3 in osteosarcoma cells.
    The Journal of biological chemistry, 1984, May-10, Volume: 259, Issue:9

    Topics: Amanitins; Animals; Calcitriol; Calcium-Binding Proteins; Cell Line; Clone Cells; Cycloheximide; Dactinomycin; Kinetics; Osteocalcin; Osteosarcoma; Rats; Transcription, Genetic

1984
The fate of liposome-entrapped actinomycin D in vivo and its therapeutic effect in a solid murine tumour [proceedings].
    Biochemical Society transactions, 1980, Volume: 8, Issue:1

    Topics: Animals; Dactinomycin; Drug Stability; Kinetics; Liposomes; Mice; Osteosarcoma; Phosphatidylcholines; Sarcoma, Experimental

1980
The effect of liposome (phospholipid vesicle) entrapment of actinomycin D and methotrexate on the in vivo treatment of sensitive and resistant solid murine tumours.
    European journal of cancer, 1981, Volume: 17, Issue:3

    Topics: Animals; Dactinomycin; Dose-Response Relationship, Drug; Drug Resistance; Female; Liposomes; Methotrexate; Mice; Mice, Inbred AKR; Osteosarcoma; Sarcoma, Experimental; Tissue Distribution

1981
Concepts for controlling drug-resistant tumor cells.
    European journal of cancer, 1980, Volume: Suppl 1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Body Burden; Cisplatin; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Resistance; Fluorouracil; Leukemia L1210; Leukemia P388; Mammary Neoplasms, Experimental; Mice; Osteosarcoma; Sarcoma, Experimental

1980
Osteosarcoma following radiation treatment for meningioma: report of a case and effective treatment with chemotherapy.
    Journal of neuro-oncology, 1994, Volume: 21, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carboplatin; Cisplatin; Dactinomycin; Etoposide; Female; Gonadotropin-Releasing Hormone; Humans; Ifosfamide; Lung Neoplasms; Meningeal Neoplasms; Meningioma; Methotrexate; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Osteosarcoma; Tamoxifen; Tomography, X-Ray Computed; Vincristine

1994
A monocentric therapy study: an approach to optimize the results of the treatment of osteosarcoma by protocols based upon HDMTX, associated with systematic conservative surgery.
    Cancer treatment and research, 1993, Volume: 62

    Topics: Actuarial Analysis; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Clinical Protocols; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Follow-Up Studies; Humans; Ifosfamide; Leucovorin; Methotrexate; Middle Aged; Osteosarcoma; Pilot Projects; Remission Induction; Salvage Therapy; Treatment Outcome; Vincristine

1993
Osteosarcoma: experience with the Rosen T10 protocol at RCH, Melbourne.
    Cancer treatment and research, 1993, Volume: 62

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Leucovorin; Life Tables; Male; Methotrexate; Osteosarcoma; Survival Rate; Treatment Outcome; Victoria; Vincristine

1993
Magnetic resonance relaxation times of normal tissue in the course of chemotherapy: a study in patients with bone sarcoma.
    Skeletal radiology, 1994, Volume: 23, Issue:3

    Topics: Adipose Tissue; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Neoplasms; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Muscles; Osteosarcoma; Preoperative Care; Sarcoma, Ewing; Vincristine

1994
Hyperthermic isolation limb perfusion (HILP) in the management of extremity melanoma and sarcoma with particular reference to the dosage, pharmacokinetics, and toxicity of cisplatin.
    Cancer treatment and research, 1993, Volume: 62

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Chemotherapy, Cancer, Regional Perfusion; Cisplatin; Combined Modality Therapy; Dacarbazine; Dactinomycin; Evaluation Studies as Topic; Extremities; Humans; Hyperthermia, Induced; Incidence; Melanoma; Melphalan; Neoplasm Metastasis; Osteosarcoma; Rhabdomyolysis; Skin Neoplasms; Treatment Outcome

1993
Long-term pulmonary toxicity of multiagent chemotherapy including bleomycin and cyclophosphamide in osteosarcoma survivors.
    Medical and pediatric oncology, 1996, Volume: 27, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Cyclophosphamide; Dactinomycin; Doxorubicin; Forced Expiratory Volume; Humans; Lung; Methotrexate; Osteosarcoma; Pulmonary Diffusing Capacity; Total Lung Capacity

1996
Helix-loop-helix-type transcription factor (HES-1) is expressed in osteoblastic cells, suppressed by 1,25(OH)2 vitamin D3, and modulates 1,25(OH)2 vitamin D3 enhancement of osteopontin gene expression.
    Bone, 1997, Volume: 20, Issue:4

    Topics: Animals; Blotting, Northern; Bone Neoplasms; Calcitriol; Cell Adhesion; Cell Division; Cycloheximide; Dactinomycin; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Neoplastic; Helix-Loop-Helix Motifs; Nucleic Acid Synthesis Inhibitors; Osteoblasts; Osteopontin; Osteosarcoma; Protein Synthesis Inhibitors; Rats; RNA, Messenger; Sialoglycoproteins; TCF Transcription Factors; Transcription Factor 7-Like 1 Protein; Transcription Factors; Tumor Cells, Cultured; Up-Regulation

1997
Primary intracerebral small-cell osteosarcoma in an adolescent girl: report of a case.
    Journal of neuro-oncology, 1997, Volume: 32, Issue:2

    Topics: Adolescent; Antineoplastic Agents; Bleomycin; Brain Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Magnetic Resonance Imaging; Osteosarcoma; Radiotherapy, Adjuvant

1997
Synthesis and cellular characterization of the detransformation agent, (-)-depudecin.
    Chemistry & biology, 1995, Volume: 2, Issue:8

    Topics: 3T3 Cells; Actins; Alkadienes; Animals; Bone Neoplasms; Cell Nucleus; Cell Transformation, Neoplastic; Cycloheximide; Cytoskeleton; Dactinomycin; Epoxy Compounds; Fatty Alcohols; Genes, ras; Magnetic Resonance Spectroscopy; Mice; Osteosarcoma; Protein Synthesis Inhibitors; Signal Transduction; Spectrophotometry, Infrared; Stereoisomerism; Tumor Cells, Cultured

1995
Regulation of the transcription of parathyroid-hormone/parathyroid-hormone-related peptide receptor mRNA by dexamethasone in ROS 17/2.8 osteosarcoma cells.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1998, Volume: 13, Issue:3

    Topics: Animals; Antineoplastic Agents, Hormonal; Bone Neoplasms; Cycloheximide; Dactinomycin; Dexamethasone; Half-Life; Osteosarcoma; Parathyroid Hormone-Related Protein; Protein Biosynthesis; Protein Synthesis Inhibitors; Proteins; Rats; Receptors, Parathyroid Hormone; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured

1998
Green fluorescent protein tag for studies of drug-induced translocation of nucleolar protein RH-II/Gu.
    BioTechniques, 1998, Volume: 24, Issue:6

    Topics: Biological Transport; Carrier Proteins; Cell Nucleolus; Dactinomycin; Green Fluorescent Proteins; Humans; Luminescent Proteins; Nuclear Proteins; Osteosarcoma; Protein Inhibitors of Activated STAT; RNA Helicases; RNA Nucleotidyltransferases; Small Ubiquitin-Related Modifier Proteins; Toyocamycin; Tumor Cells, Cultured; Zinc Fingers

1998
Identification of active substances from Streptomyces culture fluids using p53-independent expression of p21/WAF1/Cip1 gene and their mode of action.
    Biological & pharmaceutical bulletin, 1998, Volume: 21, Issue:9

    Topics: Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dactinomycin; Enzyme Inhibitors; Gene Expression Regulation, Bacterial; Genes, p53; Genes, Regulator; Genes, Reporter; Humans; Hydroxamic Acids; Luciferases; Microbial Sensitivity Tests; Osteosarcoma; Phosphotransferases; Protein Synthesis Inhibitors; RNA, Messenger; Sp1 Transcription Factor; Stomach Neoplasms; Streptomyces; Transfection; Transformation, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1998
Promoter specificity and stability control of the p53-related protein p73.
    Oncogene, 1999, Jul-22, Volume: 18, Issue:29

    Topics: Adenovirus E1A Proteins; Bone Neoplasms; Cysteine Endopeptidases; Dactinomycin; DNA-Binding Proteins; GADD45 Proteins; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, myc; Genes, p53; Genes, Reporter; Genes, Tumor Suppressor; Humans; Intracellular Signaling Peptides and Proteins; Multienzyme Complexes; Multigene Family; Neoplasm Proteins; Nuclear Proteins; Nucleic Acid Synthesis Inhibitors; Osteosarcoma; Promoter Regions, Genetic; Proteasome Endopeptidase Complex; Protein Isoforms; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Proto-Oncogene Proteins p21(ras); Recombinant Fusion Proteins; RNA Splicing; Sequence Deletion; Trans-Activators; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tumor Protein p73; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

1999
Inhibitors of protein synthesis and RNA synthesis protect against okadaic acid-induced apoptosis in human osteosarcoma cell line MG63 cells but not in Saos-2 cells.
    Journal of bone and mineral metabolism, 1999, Volume: 17, Issue:4

    Topics: Apoptosis; Cell Nucleus; Cycloheximide; Dactinomycin; DNA Fragmentation; Enzyme Inhibitors; Humans; Okadaic Acid; Osteosarcoma; Protein Synthesis Inhibitors; Puromycin; RNA; Tumor Cells, Cultured

1999
[Primary chemotherapy with the Rosen T10 protocol before conservative surgery in limb primitive osteosarcomas: results about 56 cases].
    Bulletin du cancer, 2000, Volume: 87, Issue:2

    Topics: Adolescent; Adult; Alkaline Phosphatase; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; L-Lactate Dehydrogenase; Leucovorin; Magnetic Resonance Imaging; Male; Methotrexate; Osteosarcoma; Prospective Studies; Survival Analysis; Tomography, X-Ray Computed; Vincristine

2000
Glucocorticoids induce a near-total suppression of hyaluronan synthase mRNA in dermal fibroblasts and in osteoblasts: a molecular mechanism contributing to organ atrophy.
    The Biochemical journal, 2000, Jul-01, Volume: 349, Issue:Pt 1

    Topics: Atrophy; Blotting, Northern; Cell Nucleus; Cells, Cultured; Cloning, Molecular; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Fibroblasts; Glucocorticoids; Glucuronosyltransferase; Glycosyltransferases; Hormone Antagonists; Humans; Hyaluronan Synthases; Membrane Proteins; Mifepristone; Nucleic Acid Synthesis Inhibitors; Osteoblasts; Osteosarcoma; RNA, Messenger; Skin; Time Factors; Transcription, Genetic; Transferases; Tumor Cells, Cultured; Uridine; Xenopus Proteins

2000
Transient posterior encephalopathy induced by chemotherapy in children.
    Pediatric neurology, 2001, Volume: 24, Issue:2

    Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain; Child; Cyclophosphamide; Dactinomycin; Female; Humans; Hypertension; Magnesium Deficiency; Male; Methotrexate; Neurotoxicity Syndromes; Osteosarcoma; Radiopharmaceuticals; Remission Induction; Syndrome; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon

2001
1,25-Dihydroxyvitamin D3 selectively translocates PKCalpha to nuclei in ROS 17/2.8 cells.
    Molecular and cellular endocrinology, 2002, Feb-25, Volume: 188, Issue:1-2

    Topics: Blotting, Northern; Bone Neoplasms; Calcitriol; Calcium Channel Agonists; Cell Nucleus; Dactinomycin; Fluorescent Antibody Technique; Gene Expression; Humans; Immunoblotting; Isoenzymes; Osteocalcin; Osteosarcoma; Protein Kinase C; Protein Kinase C-alpha; RNA, Messenger; Subcellular Fractions; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured

2002
[Planning of chemotherapy in cancer of children].
    Nihon rinsho. Japanese journal of clinical medicine, 1975, May-10, Volume: 33, Issue:5

    Topics: Age Factors; Child; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Humans; Neuroblastoma; Osteosarcoma; Rhabdomyosarcoma; Wilms Tumor

1975
Combination chemotherapy with bleomycin, cyclophosphamide and dactinomycin for the treatment of osteogenic sarcoma.
    Cancer, 1977, Volume: 40, Issue:6

    Topics: Adolescent; Bleomycin; Bone Marrow; Bone Neoplasms; Child; Cyclophosphamide; Dactinomycin; Drug Therapy, Combination; Female; Humans; Lung Neoplasms; Male; Neoplasm Metastasis; Osteosarcoma; Vomiting

1977
Comparative antitumor activity of actinomycin analogs in mice bearing Ridgway osteogenic sarcoma or P388 leukemia.
    Cancer treatment reports, 1978, Volume: 62, Issue:5

    Topics: Animals; Antineoplastic Agents; Dactinomycin; Leukemia, Experimental; Mice; Mice, Inbred AKR; Mice, Inbred C57BL; Mice, Inbred DBA; Osteosarcoma; Sarcoma, Experimental

1978
Malignant bone tumors: spindle-cell sarcomas.
    Pediatric annals, 1978, Volume: 7, Issue:8

    Topics: Adolescent; Amputation, Surgical; Bleomycin; Bone Neoplasms; Child; Cyclophosphamide; Dactinomycin; Dose-Response Relationship, Drug; Humans; Leucovorin; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Preoperative Care; Prostheses and Implants; Radiography; Vincristine

1978
[Cytostatic treatment as supplement in osteosarcoma and Ewing's sarcoma. Preliminary communication (author's transl)].
    Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca, 1979, Volume: 46, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Agents; Bone Neoplasms; Child; Cyclophosphamide; Dactinomycin; Drug Therapy, Combination; Female; Humans; Long-Term Care; Male; Osteosarcoma; Prognosis; Sarcoma, Ewing; Vincristine

1979
Simultaneous radiation and drug therapy: tumor response and toxicity.
    Journal of surgical oncology, 1977, Volume: 9, Issue:6

    Topics: Adult; Antineoplastic Agents; Bone Neoplasms; Dactinomycin; Doxorubicin; Female; Humans; Male; Neoplasms; Osteosarcoma; Radiotherapy; Rhabdomyosarcoma; Soft Tissue Neoplasms; Vincristine

1977
Multidisciplinary treatment for childhood sarcoma.
    American journal of surgery, 1977, Volume: 133, Issue:4

    Topics: Adolescent; Age Factors; Antineoplastic Agents; Bone Neoplasms; Child; Child, Preschool; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infant; Leucovorin; Lymphatic Metastasis; Male; Methods; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Rhabdomyosarcoma; Sarcoma; Sarcoma, Ewing; Soft Tissue Neoplasms; Vincristine

1977
Current concepts in the management of disseminated malignant bone disease in childhood.
    Canadian journal of surgery. Journal canadien de chirurgie, 1977, Volume: 20, Issue:6

    Topics: Bone Neoplasms; Child; Cyclophosphamide; Dactinomycin; Doxorubicin; Humans; Leucovorin; Methotrexate; Osteosarcoma; Sarcoma, Ewing; Vincristine

1977
Bone sarcomas: clinical experience.
    Canadian journal of surgery. Journal canadien de chirurgie, 1977, Volume: 20, Issue:6

    Topics: Age Factors; Bone Neoplasms; Chondrosarcoma; Cyclophosphamide; Dactinomycin; Doxorubicin; Humans; Leucovorin; Osteosarcoma; Sarcoma, Ewing; Vincristine

1977
Radiation in bone sarcomas: a re-evaluation in the era of intensive systemic chemotherapy.
    Cancer, 1977, Volume: 39, Issue:2 Suppl

    Topics: Bone Neoplasms; Child; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Humans; Leucovorin; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Radiation Tolerance; Radiotherapy Dosage; Radiotherapy, High-Energy; Sarcoma, Ewing; Vincristine

1977
7-substituted actinomycin D analogs. Chemical and growth-inhibitory studies.
    Journal of medicinal chemistry, 1975, Volume: 18, Issue:12

    Topics: Animals; Dactinomycin; Humans; Lactobacillus; Leukemia L1210; Leukemia, Experimental; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred Strains; Osteosarcoma; Sarcoma, Experimental; Structure-Activity Relationship

1975
[Supplementary antiblastic polychemotherapy in localized malignant bone tumors. I. Ewing's sarcoma and osteosarcoma].
    La Chirurgia degli organi di movimento, 1975, Volume: 62, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Agents; Child; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged; Osteosarcoma; Sarcoma, Ewing; Vincristine

1975
Management of malignant bone tumors in children and adolescents.
    Pediatric clinics of North America, 1976, Volume: 23, Issue:1

    Topics: Adolescent; Bone Neoplasms; Child; Cyclophosphamide; Dactinomycin; Diagnosis, Differential; Doxorubicin; Drug Therapy, Combination; Female; Humans; Male; Neoplasm Metastasis; Osteosarcoma; Prognosis; Sarcoma, Ewing; Vincristine

1976
Disposition of [3H]actinomycin D in tumor-bearing mice.
    Cancer research, 1976, Volume: 36, Issue:4

    Topics: Animals; Dactinomycin; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred Strains; Osteosarcoma; Regression Analysis; Sarcoma, Experimental

1976
Chemotherapy for nonmetastatic osteogenic sarcoma: the Memorial Sloan-Kettering experience.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1992, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bleomycin; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Male; Methotrexate; Osteosarcoma; Proportional Hazards Models; Risk Factors; Survival Analysis

1992
Primary treatment of pelvic osteosarcoma. Report of five cases.
    Cancer, 1992, Mar-01, Volume: 69, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Etoposide; Fluid Therapy; Follow-Up Studies; Humans; Ifosfamide; Injections, Intra-Arterial; Lung Neoplasms; Osteosarcoma; Pelvic Bones; Radiotherapy Dosage; Survival Rate

1992
The effect of transforming growth factor beta on the plasminogen activator activity of normal human osteoblast-like cells and a human osteosarcoma cell line MG-63.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1992, Volume: 7, Issue:12

    Topics: Bone Remodeling; Cells, Cultured; Cycloheximide; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Humans; Indomethacin; Interleukin-1; Osteoblasts; Osteosarcoma; Recombinant Proteins; Tissue Plasminogen Activator; Transforming Growth Factor beta; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator

1992
Ten years' experience in patients with osteogenic sarcoma in Finland.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1990, Volume: 16, Issue:2

    Topics: Actuarial Analysis; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Finland; Humans; Male; Methotrexate; Osteosarcoma; Survival Rate

1990
Unusually long survival time after resection and irradiation of a brain metastasis from osteosarcoma.
    Neurosurgical review, 1990, Volume: 13, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms; Child; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Femoral Neoplasms; Humans; Interferon Type I; Male; Methotrexate; Osteosarcoma; Prognosis

1990
Disposition of high-dose methotrexate in an obese cancer patient.
    Cancer, 1991, Sep-15, Volume: 68, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Half-Life; Humans; Leucovorin; Methotrexate; Obesity; Osteosarcoma; Tibia; Vincristine

1991
Stage IIB osteogenic sarcoma.
    Clinical orthopaedics and related research, 1991, Issue:270

    Topics: Adolescent; Adult; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Child, Preschool; Clinical Protocols; Cohort Studies; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; New York City; Osteosarcoma; Osteotomy; Postoperative Care; Predictive Value of Tests; Preoperative Care; Survival Analysis; Survival Rate

1991
Treatment of osteosarcoma of the extremities with the T-10 protocol, with emphasis on the effects of preoperative chemotherapy with single-agent high-dose methotrexate: a Scandinavian Sarcoma Group study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1991, Volume: 9, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arm; Bleomycin; Bone Neoplasms; Child; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Leg; Male; Methotrexate; Osteosarcoma; Survival Analysis

1991
Glucocorticoid regulation of plasminogen activator inhibitor-1 messenger ribonucleic acid and protein in normal and malignant rat osteoblasts.
    Endocrinology, 1992, Volume: 130, Issue:2

    Topics: Animals; Animals, Newborn; Blotting, Northern; Cell Line; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Dihydrotestosterone; Estradiol; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Kinetics; Osteoblasts; Osteosarcoma; Plasminogen Activators; Plasminogen Inactivators; Progesterone; Rats; RNA, Messenger

1992
Circumvention of pleiotropic drug resistance in subcutaneous tumours in vivo with verapamil and clomipramine.
    European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Clomipramine; Dactinomycin; Doxorubicin; Drug Resistance; Etoposide; Female; Male; Mice; Mice, Inbred AKR; Osteosarcoma; Verapamil; Vincristine

1991
Transforming growth factor beta inhibits plasminogen activator (PA) activity and stimulates production of urokinase-type PA, PA inhibitor-1 mRNA, and protein in rat osteoblast-like cells.
    Journal of cellular physiology, 1991, Volume: 149, Issue:1

    Topics: Animals; Cycloheximide; Dactinomycin; Fibrinolysin; Osteoblasts; Osteosarcoma; Plasminogen Activators; Plasminogen Inactivators; Protein Biosynthesis; Rats; RNA, Messenger; Tissue Plasminogen Activator; Transforming Growth Factor beta; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator

1991
[Effect by proliferation kinetics of malignant tumors of children of hyperthermia].
    Acta histochemica. Supplementband, 1990, Volume: 39

    Topics: Autoradiography; Bone Neoplasms; Cell Division; Child; Cyclophosphamide; Dactinomycin; Doxorubicin; Hot Temperature; Humans; In Vitro Techniques; Kidney Neoplasms; Neoplasms, Germ Cell and Embryonal; Neuroblastoma; Osteosarcoma; Rhabdomyosarcoma; Thymidine; Tritium; Uridine; Wilms Tumor

1990
The role of hyperthermic perfusion in the treatment of tumors of the extremities.
    Advances in experimental medicine and biology, 1990, Volume: 267

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusion; Cisplatin; Dactinomycin; Extracorporeal Circulation; Extremities; Humans; Hyperthermia, Induced; Melanoma; Melphalan; Neoplasm Recurrence, Local; Osteosarcoma; Sarcoma; Soft Tissue Neoplasms; Survival Rate

1990
Stimulation by defined parathyroid hormone fragments of cell proliferation in skeletal-derived cell cultures.
    The Biochemical journal, 1990, Dec-15, Volume: 272, Issue:3

    Topics: Animals; Cell Division; Cell Line; Cells, Cultured; Creatine Kinase; Cyclic AMP; Cycloheximide; Dactinomycin; DNA Replication; Embryo, Mammalian; Enzyme Induction; Growth Plate; Humans; Kinetics; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Peptide Fragments; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1990
Mechanism of glucocorticoid regulation of alkaline phosphatase gene expression in osteoblast-like cells.
    European journal of biochemistry, 1990, Feb-22, Volume: 188, Issue:1

    Topics: Alkaline Phosphatase; Animals; Antibodies, Monoclonal; Blotting, Northern; Cell Line; Cycloheximide; Dactinomycin; Dexamethasone; Dichlororibofuranosylbenzimidazole; Drug Interactions; Gene Expression Regulation, Enzymologic; Molecular Probes; Osteoblasts; Osteosarcoma; Puromycin; Rats; RNA, Messenger; Transcription, Genetic

1990
[Bone scintigraphy in assessing the success of chemotherapy in osteosarcoma].
    Nuklearmedizin. Nuclear medicine, 1985, Volume: 24, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone and Bones; Bone Neoplasms; Child; Cisplatin; Cyclophosphamide; Dactinomycin; Diphosphonates; Drug Evaluation; Female; Humans; Male; Osteosarcoma; Preoperative Care; Radionuclide Imaging; Technetium; Technetium Tc 99m Medronate; Time Factors

1985
[Successful treatment of several metachronous pulmonary metastases of a chondroblastic osteosarcoma].
    Zeitschrift fur Kinderchirurgie : organ der Deutschen, der Schweizerischen und der Osterreichischen Gesellschaft fur Kinderchirurgie = Surgery in infancy and childhood, 1985, Volume: 40, Issue:4

    Topics: Amputation, Surgical; Bleomycin; Child; Chondroblastoma; Cyclophosphamide; Dactinomycin; Female; Humans; Ifosfamide; Leucovorin; Lung Neoplasms; Methotrexate; Osteosarcoma; Tibia

1985
The angiographic response of osteosarcoma following pre-operative chemotherapy.
    Skeletal radiology, 1986, Volume: 15, Issue:2

    Topics: Adolescent; Adult; Angiography; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Cisplatin; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Male; Methotrexate; Osteosarcoma; Preoperative Care; Vincristine

1986
Telangiectatic osteogenic sarcoma. Improved survival with combination chemotherapy.
    Clinical orthopaedics and related research, 1986, Issue:207

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Leucovorin; Male; Methotrexate; Osteosarcoma

1986
Neoadjuvant chemotherapy for osteogenic sarcoma: a model for the treatment of other highly malignant neoplasms.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1986, Volume: 103

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Humans; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma

1986
Disparate histologic responses in simultaneously resected primary and metastatic osteosarcoma following intravenous neoadjuvant chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:8

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Necrosis; Osteosarcoma; Postoperative Care; Preoperative Care; Vincristine

1987
Translocation t(9;11)(p21;q23) with acute myelomonocytic leukemia after chemotherapy for osteosarcoma: good response to antileukemic drugs.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:8

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 9; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Methotrexate; Neoplasms, Multiple Primary; Osteosarcoma; Translocation, Genetic

1987
[The reproduction in France of Rosen's protocol for osteosarcomas].
    Bulletin du cancer, 1988, Volume: 75, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Administration Schedule; Female; Humans; Male; Methotrexate; Middle Aged; Osteosarcoma; Prognosis

1988
[Experience with protocol T10 in the pediatric service at the Gustave-Roussy Institute].
    Bulletin du cancer, 1988, Volume: 75, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Administration Schedule; Female; Humans; Infant; Male; Methotrexate; Osteosarcoma; Prognosis

1988
Neutrophilic eccrine hidradenitis. Evidence implicating bleomycin as a causative agent.
    Cancer, 1988, Dec-15, Volume: 62, Issue:12

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Cyclophosphamide; Dactinomycin; Eccrine Glands; Female; Humans; Inflammation; Neutrophils; Osteosarcoma; Sweat Gland Diseases

1988
Bone Gla protein messenger ribonucleic acid is regulated by both 1,25-dihydroxyvitamin D3 and 3',5'-cyclic adenosine monophosphate in rat osteosarcoma cells.
    Molecular endocrinology (Baltimore, Md.), 1989, Volume: 3, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcitriol; Calcium-Binding Proteins; Cell Count; Cholera Toxin; Colforsin; Cyclic AMP; Dactinomycin; Gene Expression Regulation; Osteocalcin; Osteosarcoma; Parathyroid Hormone; Pertussis Toxin; Rats; RNA, Messenger; Tumor Cells, Cultured; Virulence Factors, Bordetella

1989
[Preoperative systemic chemotherapy of patients with osteosarcoma: a preliminary study of nine cases].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:4 Pt 2-3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Humans; Male; Methotrexate; Osteosarcoma; Premedication

1989
[Mirror-image osteosarcoma of the radius. A case].
    Presse medicale (Paris, France : 1983), 1989, Jun-24, Volume: 18, Issue:25

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Follow-Up Studies; Humans; Methotrexate; Neoplasms, Multiple Primary; Osteosarcoma; Prognosis; Radius

1989
Primary chemotherapy and delayed surgery (neoadjuvant chemotherapy) for telangiectatic osteogenic sarcoma of the extremities.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:3

    Topics: Adolescent; Adult; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Arm; Bleomycin; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Female; Follow-Up Studies; Humans; Leg; Male; Methotrexate; Osteosarcoma; Postoperative Complications; Premedication

1989
Secondary cerebral astrocytoma 3 years after diagnosis of primary osteogenic sarcoma: a case report.
    Pediatric hematology and oncology, 1987, Volume: 4, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Bleomycin; Brain Neoplasms; Child; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Electroencephalography; Femoral Neoplasms; Humans; Male; Methotrexate; Neoplasms, Multiple Primary; Osteosarcoma

1987
Evidence that the self-induced metabolism of 1,25-dihydroxyvitamin D-3 limits the homologous up-regulation of its receptor in rat osteosarcoma cells.
    Biochimica et biophysica acta, 1988, Jun-30, Volume: 970, Issue:2

    Topics: Animals; Calcitriol; Cell Line; Culture Media; Cycloheximide; Dactinomycin; Ketoconazole; Kinetics; Osteosarcoma; Rats; Receptors, Calcitriol; Receptors, Steroid; Tumor Cells, Cultured

1988
Heterologous up-regulation of the 1,25-dihydroxyvitamin D3 receptor by parathyroid hormone (PTH) and PTH-like peptide in osteoblast-like cells.
    Biochemical and biophysical research communications, 1988, Oct-14, Volume: 156, Issue:1

    Topics: Animals; Calcitriol; Cell Line; Cyclic AMP; Cycloheximide; Dactinomycin; Kinetics; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Peptide Fragments; Rats; Receptors, Calcitriol; Receptors, Steroid; Teriparatide

1988
Early manifestations of vitamin D effects in rat osteogenic sarcoma cells.
    Calcified tissue international, 1987, Volume: 41, Issue:4

    Topics: Animals; Bone Neoplasms; Calcitriol; Calcium; Cell Count; Cell Line; Dactinomycin; Dose-Response Relationship, Drug; Osteosarcoma; Rats; Tumor Cells, Cultured

1987
Mechanism of actinomycin D-induced resistance in Ridgway osteogenic sarcoma: an ultrastructural study.
    Journal of submicroscopic cytology and pathology, 1988, Volume: 20, Issue:1

    Topics: Animals; Cell Line; Dactinomycin; Disease Models, Animal; Drug Resistance; Female; Male; Mice; Microscopy, Electron; Osteosarcoma; Sarcoma, Experimental; Tumor Cells, Cultured

1988
Transcriptional regulation of osteopontin production in rat osteosarcoma cells by type beta transforming growth factor.
    The Journal of biological chemistry, 1988, Sep-25, Volume: 263, Issue:27

    Topics: Animals; Calcitriol; Collagen; Dactinomycin; Dexamethasone; Electrophoresis, Polyacrylamide Gel; Fibronectins; Half-Life; Kinetics; Osteoblasts; Osteopontin; Osteosarcoma; Peptides; Rats; RNA, Messenger; Sialoglycoproteins; Transcription, Genetic; Transforming Growth Factors; Tumor Cells, Cultured

1988
[Autologous bone marrow transplantation in osteosarcoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:5 Pt 2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Bone Neoplasms; Child; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Male; Melphalan; Methotrexate; Osteosarcoma; Transplantation, Autologous

1987
Effects of transforming growth factor-beta on osteoblastic osteosarcoma cells.
    Endocrinology, 1987, Volume: 121, Issue:1

    Topics: Alkaline Phosphatase; Animals; Calcitriol; Cell Division; Cell Line; Collagen; Cycloheximide; Dactinomycin; DNA; Growth Substances; Osteoblasts; Osteosarcoma; Peptides; Rats; Transforming Growth Factors

1987
1,25-Dihydroxyvitamin D3 regulates the biosynthesis of osteopontin, a bone-derived cell attachment protein, in clonal osteoblast-like osteosarcoma cells.
    Collagen and related research, 1987, Volume: 7, Issue:4

    Topics: Animals; Calcitriol; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Molecular Weight; Osteoblasts; Osteopontin; Osteosarcoma; Phosphoproteins; Phosphorylation; Radioimmunoassay; Rats; Sialoglycoproteins

1987
Phenotype-associated changes in the effects of 1,25-dihydroxyvitamin D3 on alkaline phosphatase and bone GLA-protein of rat osteoblastic cells.
    Endocrinology, 1986, Volume: 118, Issue:4

    Topics: Alkaline Phosphatase; Animals; Calcitriol; Calcium-Binding Proteins; Cell Line; Clone Cells; Dactinomycin; Osteoblasts; Osteocalcin; Osteosarcoma; Phenotype; Rats; Time Factors

1986
Interleukin 1 and poly(rI).poly(rC) induce production of a hybridoma growth factor by human fibroblasts.
    European journal of immunology, 1987, Volume: 17, Issue:1

    Topics: Animals; B-Lymphocytes; Biological Products; Cell Line; Cells, Cultured; Concanavalin A; Cricetinae; Cricetulus; Cycloheximide; Cytokines; Dactinomycin; Female; Fibroblasts; Growth Substances; Humans; Hybridomas; Interferon Type I; Interleukin-1; Kinetics; L Cells; Leukocytes; Mice; Osteosarcoma; Ovary; Poly I-C; Skin

1987
Glucocorticoid regulation of alkaline phosphatase in the osteoblastic osteosarcoma cell line ROS 17/2.8.
    Endocrinology, 1985, Volume: 116, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alkaline Phosphatase; Animals; Cell Division; Cell Line; Cycloheximide; Dactinomycin; Dexamethasone; Isoproterenol; Kinetics; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Rats

1985
Synthesis of actinomycin D lactam, [1',1'-bis(L-threo- , -diaminobutyric acid)]actinomycin D.
    Journal of medicinal chemistry, 1973, Volume: 16, Issue:4

    Topics: Aminobutyrates; Animals; Antibiotics, Antineoplastic; Dactinomycin; Lactams; Lacticaseibacillus casei; Lactobacillus; Lethal Dose 50; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred Strains; Osteosarcoma; Sarcoma, Experimental

1973
Treatment of pulmonary metastatic disease with radiation therapy and adjuvant actinomycin D. Preliminary observations.
    Cancer, 1969, Volume: 24, Issue:4

    Topics: Adenocarcinoma; Adult; Carcinoma, Squamous Cell; Cobalt Isotopes; Dactinomycin; Ependymoma; Female; Fibrosarcoma; Hemangiopericytoma; Hemangiosarcoma; Humans; Infusions, Parenteral; Liposarcoma; Lung Neoplasms; Male; Mesenchymoma; Osteosarcoma; Radiotherapy Dosage; Radiotherapy, High-Energy; Retrospective Studies; Rhabdomyosarcoma; Sarcoma; Sarcoma, Ewing; Sarcoma, Synovial; Teratoma

1969
Blood and neoplastic diseases. Solid tumours in children.
    British medical journal, 1974, Dec-21, Volume: 4, Issue:5946

    Topics: Adolescent; Biopsy; Child; Child, Preschool; Cyclophosphamide; Dactinomycin; Diagnosis, Differential; Doxorubicin; Hodgkin Disease; Humans; Infant; Methods; Methotrexate; Neoplasms; Neuroblastoma; Nitrogen Mustard Compounds; Osteosarcoma; Prednisolone; Prognosis; Radiography; Retinoblastoma; Rhabdomyosarcoma; Sarcoma, Ewing; Vincristine; Wilms Tumor

1974
Different sensitivity to actinomycin D of biopsies of human tumors cultivated in vitro.
    European journal of cancer, 1973, Volume: 9, Issue:4

    Topics: Biopsy; Carcinoma; Cells, Cultured; Dactinomycin; Humans; Osteosarcoma; Sarcoma; Time Factors

1973
Combined intra-arterial chemotherapy and radiotherapy with special reference to osteogenic sarcoma.
    Annals of clinical research, 1974, Volume: 6, Issue:6

    Topics: Adolescent; Angiography; Cobalt Radioisotopes; Dactinomycin; Female; Femur; Humans; Injections, Intra-Arterial; Male; Osteosarcoma; Radioisotope Teletherapy

1974
Results in 169 patients with cancer of the head and neck treated by intra-arterial infusion therapy.
    American journal of surgery, 1972, Volume: 124, Issue:4

    Topics: Antineoplastic Agents; Brachial Artery; Brachiocephalic Trunk; Carcinoma, Squamous Cell; Carotid Artery, Internal; Catheterization; Cyclophosphamide; Dactinomycin; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Laryngeal Neoplasms; Melanoma; Methods; Methotrexate; Mouth Neoplasms; Neoplasms; Osteosarcoma; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Skin Neoplasms; Skull Neoplasms; Vinblastine

1972
[Chemotherapy of bone tumors].
    Helvetica chirurgica acta, 1973, Volume: 40, Issue:1

    Topics: Antineoplastic Agents; Bone Neoplasms; Cyclophosphamide; Dactinomycin; Doxorubicin; Humans; Lymphoma, Large B-Cell, Diffuse; Osteosarcoma; Sarcoma, Ewing; Vincristine

1973
The enhanced response of the Ridgway osteogenic sarcoma to roentgen radiation combined with actinomycin D.
    Cancer research, 1965, Volume: 25, Issue:7

    Topics: Animals; Dactinomycin; Mice; Osteosarcoma; Sarcoma, Experimental

1965
The effect of combined radiation and actinomycin D therapy on incompletely removed mouse tumors.
    The American journal of roentgenology, radium therapy, and nuclear medicine, 1966, Volume: 97, Issue:4

    Topics: Animals; Dactinomycin; Osteosarcoma; Sarcoma, Experimental

1966
Actinomycin D: effects on Ridgway osteogenic sarcoma in mice.
    Cancer research, 1966, Volume: 26, Issue:9

    Topics: Animals; Dactinomycin; Injections, Intravenous; Intermittent Claudication; Mice; Osteosarcoma; Sarcoma, Experimental

1966
Actinomycin D effects on nucleic acids during tumor regression.
    Cancer research, 1968, Volume: 28, Issue:3

    Topics: Animals; Axilla; Carbon Isotopes; Colorimetry; Dactinomycin; DNA; DNA, Neoplasm; Female; Intestine, Small; Mice; Neoplasm Proteins; Neoplasm Transplantation; Osteosarcoma; Phosphorus Isotopes; Proteins; RNA; RNA, Neoplasm; Sarcoma, Experimental; Thymidine; Uridine

1968
Actinomycin D: drug concentrations and actions in mouse tissues and tumors.
    Cancer research, 1968, Volume: 28, Issue:2

    Topics: Animals; Chromatography, Paper; Dactinomycin; Female; Intestine, Small; Liver; Mice; Neoplasms, Experimental; Osteosarcoma; RNA; Salivary Glands; Spleen; Thymus Gland; Time Factors; Tritium; Uridine

1968
Unusual orbital neoplasms.
    American journal of ophthalmology, 1969, Volume: 68, Issue:3

    Topics: Aged; Dactinomycin; Deafness; Diplopia; Female; Humans; Middle Aged; Myxosarcoma; Neoplasm Recurrence, Local; Orbital Neoplasms; Osteitis Deformans; Osteosarcoma; Radiography; Skull; Temporal Lobe

1969
Double-stranded RNA synthesized in animal cells in the presence of actinomycin D.
    Nature, 1970, May-16, Volume: 226, Issue:5246

    Topics: Albinism; Animals; Burkitt Lymphoma; Cell Line; Centrifugation, Density Gradient; Chick Embryo; Chromatography, Gel; Dactinomycin; Fibroblasts; HeLa Cells; Hematologic Diseases; Hodgkin Disease; In Vitro Techniques; Infectious Mononucleosis; Kidney; Leukocytes; Light; Liver; Lymphocytes; Osteosarcoma; Rats; Ribonucleases; RNA; RNA, Neoplasm; Spleen; Tritium; Uridine

1970
[In vitro study of the sensitivity of osteosarcoma to antineoplastic agents: the antimitogram].
    La Presse medicale, 1971, Jun-26, Volume: 79, Issue:32

    Topics: Antineoplastic Agents; Culture Techniques; Dactinomycin; Osteosarcoma

1971
Synthesis of an actinomycin analog with substituted lactone oxygens (1',1'-bis(L-,-diaminopropionic acid))-actinomycin C (C 1).
    International journal of protein research, 1971, Volume: 3, Issue:6

    Topics: Amino Acids; Animals; Antineoplastic Agents; Benzyl Compounds; Chemical Phenomena; Chemistry; Dactinomycin; Formates; Lactams; Lactobacillus; Nitrobenzenes; Osteosarcoma; Propionates; Rats; Sarcoma, Experimental; Serine

1971