dactinomycin has been researched along with Necrosis in 58 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 21 (36.21) | 18.7374 |
1990's | 14 (24.14) | 18.2507 |
2000's | 18 (31.03) | 29.6817 |
2010's | 5 (8.62) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Chen, D; Eyupoglu, IY; Savaskan, N | 1 |
Casey, BJ; Degheidy, H; Goering, PL; Kumar, G | 1 |
Beyreis, M; Helm, K; Jakab, M; Kiesslich, T; Mayr, C; Plaetzer, K; Ritter, M | 1 |
Berg, H; Traitcheva, N | 1 |
Cai, Y; Jin, C; Liu, Q; Lu, S; Lu, X; Qi, M; Wu, S; Xi, Q | 1 |
Filgueira, L; Forte, P; Groscurth, P; Matter-Reissmann, UB; Schneider, MK; Seebach, JD | 1 |
Ali, C; Lobner, D | 1 |
BACKMANN, R | 1 |
KOLFF, WJ; NAKAMOTO, S; STRAFFON, RA | 1 |
Isobe, T; Kato, Y; Koga, M; Mizuguchi, J; Saito, M; Shibuya, H; Toyota, H; Tsuboi, R | 1 |
Jung, MJ; Kweon, MH; Sung, HC | 1 |
Atamaniuk, J; Eigner, M; Karimi, A; Mueller, MM; Ruzicka, K; Stuhlmeier, KM | 1 |
Boscolo, R; Granzotto, M; Guarnieri, S; Perticarari, S; Pozzobon, C; Presani, G; Ricci, G; Sartore, A | 1 |
Manna, SK; Raghavendra, PB; Ramesh, GT; Sreenivasan, Y | 1 |
Hentze, H; Künstle, G; Latta, M; Lucas, R; Wendel, A | 1 |
Chander, R; Deorukhkar, AA; Pandey, R; Sainis, KB | 1 |
Aringer, M; Ekhart, H; Feierl, E; Karonitsch, T; Smolen, JS; Steiner, CW; Stummvoll, GH | 1 |
Ding, WX; Ni, HM; Yin, XM | 1 |
Moore, JV | 1 |
Biswas, NM; Koley, AR | 1 |
Giorgi, JV; Schmid, I; Uittenbogaart, CH | 1 |
Avella, M; Bacci, G; Casadei, R; Cazzola, A; Ferrari, S; Lari, S; Monti, C; Picci, P; Prever, BA; Ruggieri, P | 1 |
Doupe, A; Drexler, HC; Fernandez, PA; Rangini, Z; Rotello, RJ; Yuan, J | 1 |
Cotter, TG; Fernandes, RS | 1 |
Hoorens, A; Klöppel, G; Pipeleers, D; Van de Casteele, M | 1 |
Aishita, H; Chuang, DM; Ishitani, R; Sunaga, K; Tanaka, M | 1 |
Beyaert, R; Declercq, W; Fiers, W; Vandenabeele, P; Vercammen, D | 1 |
Maher, P; Tan, S; Wood, M | 1 |
Casper, E; Gorlick, R; Healey, JH; Heller, G; Huvos, AG; Lane, J; Meyers, PA | 1 |
Chambers, JT; Cracchiolo, B; Kohorn, EI; Odunsi, KO; Parkash, V; Peck, LL; Taylor, KJ | 1 |
Ayala, A; Chaudry, IH; Evans, TA | 1 |
Blom, WM; de Bont, HJ; Meijerman, I; Mulder, GJ; Nagelkerke, JF | 1 |
An, K; Consigli, RA; Fattaey, HK; Paulsen, AQ | 1 |
Gantner, F; Hentze, H; Kolb, SA; Wendel, A | 1 |
Colombo, B; Corti, A; Curnis, F; Manfredi, AA; Pelagi, M; Rovere, P; Sacchi, A | 1 |
Falcovitz, A; Goldfinger, N; Gorbunova, V; Milyavsky, M; Rotter, V; Seluanov, A; Shohat, G; Sigal, A; Zurer, I | 1 |
Gao, LY; Kwaik, YA | 1 |
Belka, C; Berdel, WE; Kreuter, M; Los, M; Renz, A; Schulze-Osthoff, K | 1 |
Liu, BF; Liu, HH; Lu, YT; Zhang, L | 1 |
Gifford, GE; Ostrove, JM | 1 |
Firstater, M; Itzicovitch, L; Meshorer, A; Tadmor, A | 1 |
Di Chiro, G; Pratt, RA; Weed, JC | 1 |
Abbott, PJ; Harmon, B; Kerr, JF; Lawson, TA; Searle, J | 1 |
Cotter, TG | 1 |
Horn, M; Ruchelli, ED; Taylor, SR | 1 |
Dawson, P; Dean, L; Nachman, J; Shermeta, D; Simon, MA; Vogelzang, NJ | 1 |
Alvarez-Silvan, AM; Andrade Becerra, E; Anguita, ML; Gavilan Carrasco, F; Gracia Valles, MC; Maillo Arcega, MA; Martinez Caro, A; Pineda Cuevas, G | 1 |
Eversmann, WW; Loth, TS | 1 |
Kurosawa, T; Maejima, K | 1 |
Kratz, L; Ringleb, D; Sippel, W | 1 |
Alexandre, GP; Rombouts, JJ; Troch, R; Vincent, A | 1 |
Kohsaka, M; Mori, A; Takeuchi, H; Tateishi, J | 1 |
Cosgrove, MD; Helmbrecht, LJ | 1 |
Adkins, KF | 1 |
Merker, HJ; Schweichel, JU | 1 |
Ordy, JM; Samorajski, T; Zeman, W | 1 |
Baserga, R; Estensen, RD | 1 |
3 review(s) available for dactinomycin and Necrosis
Article | Year |
---|---|
Actinomycins.
Topics: Animals; Carcinogens; Dactinomycin; Drug Evaluation, Preclinical; Female; Hyperplasia; Male; Mice; Mitosis; Necrosis; Rabbits; Rats; Sarcoma; Skin; Transcription, Genetic | 1976 |
Induction of apoptosis in cells of the immune system by cytotoxic stimuli.
Topics: Animals; Aphidicolin; Apoptosis; Camptothecin; Cell Cycle; Dactinomycin; Humans; Immune System; Necrosis | 1992 |
[A review on endotoxin measurement].
Topics: Animals; Biological Assay; Body Weight; Bone Marrow; Dactinomycin; Endotoxins; Epinephrine; Hemorrhage; Lead; Lethal Dose 50; Necrosis; Organometallic Compounds; Pyrogens; Shwartzman Phenomenon; Skin Tests | 1985 |
4 trial(s) available for dactinomycin and Necrosis
Article | Year |
---|---|
Cell-free plasma DNA: a marker for apoptosis during hemodialysis.
Topics: Adult; Aged; Aged, 80 and over; Annexin A5; Apoptosis; Biomarkers; Cell Nucleus; Dactinomycin; DNA; Fluorescent Dyes; Humans; Leukocytes; Middle Aged; Necrosis; Renal Dialysis | 2006 |
Engulfed cell remnants, and not cells undergoing apoptosis, constitute the LE-cell phenomenon.
Topics: Antibodies, Antinuclear; Apoptosis; Dactinomycin; Female; Gliotoxin; Histones; Hot Temperature; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Male; Necrosis; Nucleic Acid Synthesis Inhibitors | 2007 |
Neoadjuvant chemotherapy for nonmetastatic osteosarcoma of the extremities: the recent experience at the Rizzoli Institute.
Topics: Actuarial Analysis; Adolescent; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Clinical Protocols; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Extremities; Female; Humans; Italy; Male; Methotrexate; Necrosis; Osteosarcoma; Prognosis; Salvage Therapy; Survival Analysis | 1993 |
Intensification of preoperative chemotherapy for osteogenic sarcoma: results of the Memorial Sloan-Kettering (T12) protocol.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Cyclophosphamide; Dactinomycin; Disease-Free Survival; Doxorubicin; Female; Humans; Male; Methotrexate; Necrosis; Osteosarcoma; Time Factors; Treatment Outcome | 1998 |
51 other study(ies) available for dactinomycin and Necrosis
Article | Year |
---|---|
Ferroptosis and Cell Death Analysis by Flow Cytometry.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Dactinomycin; Flow Cytometry; Humans; Indicators and Reagents; Iron; Necrosis; Niacinamide; Phenylurea Compounds; Piperazines; Propidium; Rats; Sorafenib | 2017 |
Flow cytometry evaluation of in vitro cellular necrosis and apoptosis induced by silver nanoparticles.
Topics: Animals; Annexin A5; Apoptosis; Cell Line; Cell Survival; Chemical Phenomena; Dactinomycin; Flow Cytometry; Fluorescent Dyes; Kinetics; Metal Nanoparticles; Mice; Microscopy, Electron, Transmission; Necrosis; Nephelometry and Turbidimetry; Particle Size; Rheology; Silver; Surface Properties; Toxicity Tests | 2015 |
In Vitro Cell Death Discrimination and Screening Method by Simple and Cost-Effective Viability Analysis.
Topics: Apoptosis; Biological Assay; Biomarkers; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Survival; Dactinomycin; Dose-Response Relationship, Drug; Epidermis; Gene Expression; Humans; Hydrogen Peroxide; Indicators and Reagents; Indoles; Light; Necrosis; Oxazines; Triazoles; Xanthenes | 2017 |
Electroporation and alternating current cause membrane permeation of photodynamic cytotoxins yielding necrosis and apoptosis of cancer cells.
Topics: Animals; Apoptosis; Cell Death; Cell Line, Tumor; Cell Membrane Permeability; Cytotoxins; Dactinomycin; Daunorubicin; Electrochemotherapy; Electromagnetic Fields; Electroporation; Humans; Leukemia, Erythroblastic, Acute; Lymphoma; Necrosis; Neoplasms; Photochemotherapy; Time Factors | 2010 |
Induction of the bystander effect in Chinese hamster V79 cells by actinomycin D.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Bystander Effect; Cell Line; Cell Survival; Chromosome Aberrations; Cricetinae; Cricetulus; Culture Media, Conditioned; Dactinomycin; Fibroblasts; Microscopy, Electron, Transmission; Necrosis | 2011 |
Xenogeneic human NK cytotoxicity against porcine endothelial cells is perforin/granzyme B dependent and not inhibited by Bcl-2 overexpression.
Topics: Amino Acid Chloromethyl Ketones; Ammonium Chloride; Animals; Anti-Bacterial Agents; Antigens, Heterophile; Apoptosis; Calcium; Cells, Cultured; Coculture Techniques; Cysteine Endopeptidases; Cytotoxicity, Immunologic; Dactinomycin; Endothelium, Vascular; Enzyme Inhibitors; Exocytosis; Fas Ligand Protein; Genes, bcl-2; Graft Rejection; Granzymes; Humans; Killer Cells, Natural; Macrolides; Membrane Glycoproteins; Microscopy, Electron; Necrosis; Perforin; Pore Forming Cytotoxic Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Serine Endopeptidases; Staurosporine; Swine; Tumor Necrosis Factor-alpha; Ubiquitin | 2002 |
Mechanisms of bFGF and NT-4 potentiation of necrotic neuronal death.
Topics: Animals; Apoptosis; Cells, Cultured; Cerebral Cortex; Dactinomycin; Fibroblast Growth Factor 2; Glucose; Iron Compounds; Mice; Necrosis; Nerve Growth Factors; Neuroglia; Neurons; Nifedipine; Oxygen; Polymerase Chain Reaction; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Time Factors; Vasodilator Agents | 2002 |
[RADIOAUTOGRAPHIC STUDIES ON THE UPTAKE OF H 3-ACTINOMYCIN BY MOUSE ASCITES TUMOR CELLS].
Topics: Animals; Ascites; Autoradiography; Biochemical Phenomena; Biochemistry; Carcinoma; Carcinoma, Ehrlich Tumor; Dactinomycin; DNA; DNA, Neoplasm; Mice; Necrosis; Neoplasms; Neoplasms, Experimental; Research; Tritium | 1963 |
CLINICAL EXPERIENCE WITH RENAL TRANSPLANTATION.
Topics: Azathioprine; Cadaver; Dactinomycin; Drug Therapy; Hemorrhage; Humans; Hypertension; Immunosuppressive Agents; Kidney Transplantation; Necrosis; Nephrectomy; Postoperative Complications; Prednisone; Radiotherapy; Sepsis; Splenectomy; Thymectomy; Transplantation Immunology; Transplantation, Homologous | 1965 |
Induction of apoptosis and/or necrosis following exposure to antitumour agents in a melanoma cell line, probably through modulation of Bcl-2 family proteins.
Topics: Annexin A5; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Death; Cell Line, Tumor; Cell Survival; Cisplatin; Coloring Agents; Dacarbazine; Dactinomycin; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Flow Cytometry; Fluorescent Dyes; Humans; Melanoma; Necrosis; Proto-Oncogene Proteins c-bcl-2; Time Factors; Trypan Blue; Up-Regulation | 2003 |
Cytoprotective effects of heme oxygenase-1 induction by 3-O-caffeoyl-1-methylquinic acid.
Topics: Acetylcysteine; Animals; Antioxidants; Cattle; Cell Line; Cryoprotective Agents; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Induction; Ferritins; Flow Cytometry; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hydroxybenzoates; Molecular Structure; Necrosis; Protoporphyrins; Quinic Acid; Reactive Oxygen Species; RNA, Messenger; tert-Butylhydroperoxide; Time Factors; Up-Regulation | 2004 |
A new multiparameter flow cytometric method for human semen analysis.
Topics: Adult; Apoptosis; Betulinic Acid; Caspases; Dactinomycin; Enzyme Activation; Flow Cytometry; Fluorescent Dyes; Humans; Leukocyte Common Antigens; Leukocytes; Male; Necrosis; Pentacyclic Triterpenes; Reproducibility of Results; Semen; Spermatozoa; Triterpenes | 2007 |
Cardiac glycoside induces cell death via FasL by activating calcineurin and NF-AT, but apoptosis initially proceeds through activation of caspases.
Topics: Antibodies; Apoptosis; bcl-X Protein; Calcineurin; Calcineurin Inhibitors; Calcium; Cardenolides; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cell Nucleus; Cyclosporine; Dactinomycin; DNA; Enzyme Activation; Enzyme Inhibitors; Fas Ligand Protein; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Lipids; Membrane Fluidity; Necrosis; NFATC Transcription Factors; Oligopeptides; Protein Transport; Sodium-Potassium-Exchanging ATPase | 2007 |
ATP-depleting carbohydrates prevent tumor necrosis factor receptor 1-dependent apoptotic and necrotic liver injury in mice.
Topics: Adenosine; Adenosine Triphosphate; Alanine Transaminase; Animals; Apoptosis; Caspase 3; Caspase 8; Cell Survival; Cells, Cultured; Dactinomycin; Hepatocytes; Hexoses; Interferon-gamma; Interleukin-4; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred BALB C; Models, Biological; Necrosis; NF-kappa B; Receptors, Tumor Necrosis Factor, Type I; T-Lymphocytes; Tumor Necrosis Factor-alpha | 2007 |
A novel N-alkylated prodigiosin analogue induced death in tumour cell through apoptosis or necrosis depending upon the cell type.
Topics: Alkenes; Alkylation; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Membrane Permeability; Cell Survival; Dactinomycin; Diploidy; DNA Fragmentation; DNA, Neoplasm; Enzyme Inhibitors; Lymphoma, T-Cell; Mice; Necrosis; Prodigiosin; Pyrroles; Rats; Sarcoma 180; Staurosporine; Tetrazolium Salts; Thiazoles | 2008 |
Absence of Bax switched MG132-induced apoptosis to non-apoptotic cell death that could be suppressed by transcriptional or translational inhibition.
Topics: Adenosine Triphosphate; Apoptosis; bcl-2-Associated X Protein; Cycloheximide; Dactinomycin; Endoplasmic Reticulum; HCT116 Cells; Humans; Leupeptins; Necrosis; Polyubiquitin; Proteasome Inhibitors; Protein Biosynthesis; Protein Folding; Protein Structure, Quaternary; Transcription, Genetic; Vacuoles | 2007 |
Death of intestinal crypts and of their constituent cells after treatment by chemotherapeutic drugs.
Topics: Animals; Antineoplastic Agents; Carmustine; Cell Survival; Cyclophosphamide; Dactinomycin; Doxorubicin; Fluorouracil; Intestinal Mucosa; Jejunum; Male; Mechlorethamine; Mice; Necrosis | 1984 |
The effects of actinomycin D on spermatogenesis in the toad.
Topics: Animals; Bufonidae; Dactinomycin; Male; Necrosis; Spermatocytes; Spermatogenesis; Spermatogonia; Testis | 1981 |
Sensitive method for measuring apoptosis and cell surface phenotype in human thymocytes by flow cytometry.
Topics: Adult; Antigens, CD; Apoptosis; Benzimidazoles; CD4-Positive T-Lymphocytes; Cell Separation; Child; Dactinomycin; Dexamethasone; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Antibody Technique; Fluorescent Dyes; Humans; Immunophenotyping; Necrosis; Phycoerythrin; Sensitivity and Specificity; Staining and Labeling; T-Lymphocyte Subsets; Thymus Gland | 1994 |
Expression of a specific marker of avian programmed cell death in both apoptosis and necrosis.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Apoptosis; Birds; Cells, Cultured; Chick Embryo; Dactinomycin; Fluorescent Antibody Technique; In Vitro Techniques; Necrosis | 1994 |
Apoptosis or necrosis: intracellular levels of glutathione influence mode of cell death.
Topics: Alkylating Agents; Apoptosis; Camptothecin; Cell Death; Cell Line; Chlorambucil; Dactinomycin; DNA; Glutathione; Humans; Melphalan; Necrosis | 1994 |
Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program.
Topics: Animals; Apoptosis; Cell Separation; Cell Survival; Cells, Cultured; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucose; Islets of Langerhans; Male; Microscopy, Electron; Microscopy, Fluorescence; Necrosis; Rats | 1996 |
Overexpression of glyceraldehyde-3-phosphate dehydrogenase is involved in low K+-induced apoptosis but not necrosis of cultured cerebellar granule cells.
Topics: Animals; Apoptosis; Cells, Cultured; Cerebellum; Cycloheximide; Cytoplasmic Granules; Dactinomycin; Glyceraldehyde-3-Phosphate Dehydrogenases; Necrosis; Oligonucleotides, Antisense; Potassium Deficiency; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1997 |
Tumour necrosis factor-induced necrosis versus anti-Fas-induced apoptosis in L929 cells.
Topics: Adjuvants, Immunologic; Animals; Antibodies, Monoclonal; Apoptosis; Dactinomycin; Enzyme Inhibitors; fas Receptor; Humans; Lithium Chloride; Mice; Necrosis; Nucleic Acid Synthesis Inhibitors; Serine Proteinase Inhibitors; Staurosporine; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Oxidative stress induces a form of programmed cell death with characteristics of both apoptosis and necrosis in neuronal cells.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Aurintricarboxylic Acid; Buthionine Sulfoximine; Cell Line, Transformed; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dactinomycin; DNA Fragmentation; Enzyme Inhibitors; Glutamic Acid; Glutathione Synthase; Hippocampus; Mice; Microscopy, Electron; Necrosis; Neurons; Oxidative Stress; Protein Kinase C; Protein Synthesis Inhibitors; RNA; Sulfones; Trypsin Inhibitors | 1998 |
Necrosis of myometrial choriocarcinoma with fulminating sepsis complicating chemotherapy for trophoblastic tumor.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Etoposide; Female; Humans; Methotrexate; Myometrium; Necrosis; Neoplasms, Multiple Primary; Pregnancy; Remission Induction; Sepsis; Trophoblastic Neoplasms; Uterine Neoplasms; Vincristine | 1998 |
Does hepatocellular injury in sepsis involve apoptosis?
Topics: Animals; Annexin A5; Apoptosis; Cell Membrane Permeability; Coloring Agents; Dactinomycin; Humans; Liver; Male; Mice; Mice, Inbred C3H; Necrosis; Sepsis; Tumor Necrosis Factor-alpha | 1998 |
Induction of apoptosis and changes in nuclear G-actin are mediated by different pathways: the effect of inhibitors of protein and RNA synthesis in isolated rat hepatocytes.
Topics: Actins; Animals; Apoptosis; Caspases; Cell Nucleus; Cell Survival; Cycloheximide; Dactinomycin; Emetine; Liver; Male; Necrosis; Protein Synthesis Inhibitors; Puromycin; Rats; Rats, Wistar; RNA | 1999 |
Murine polyomavirus infection of 3T6 mouse cells shows evidence of predominant necrosis as well as limited apoptosis.
Topics: Animals; Apoptosis; Caspases; Cell Line; Dactinomycin; DNA Fragmentation; Fibroblasts; Flow Cytometry; Mice; Microscopy, Electron; Necrosis; Polyomavirus | 2000 |
Depletion of hepatic glutathione prevents death receptor-dependent apoptotic and necrotic liver injury in mice.
Topics: Amanitins; Animals; Antigens, CD; Apoptosis; Caspases; Cell Death; Concanavalin A; Cytokines; Dactinomycin; Dose-Response Relationship, Drug; Glutathione; Liver; Male; Mice; Mice, Inbred BALB C; Necrosis; Nucleic Acid Synthesis Inhibitors; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Shock, Septic | 2000 |
Caspase inhibition reveals functional cooperation between p55- and p75-TNF receptors in cell necrosis.
Topics: Amino Acid Chloromethyl Ketones; Animals; Antibodies, Monoclonal; Antigens, CD; Caspase Inhibitors; Cysteine Proteinase Inhibitors; Cytotoxicity Tests, Immunologic; Dactinomycin; Humans; Mice; Mice, Inbred C57BL; Models, Biological; Necrosis; Protein Synthesis Inhibitors; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2000 |
Change of the death pathway in senescent human fibroblasts in response to DNA damage is caused by an inability to stabilize p53.
Topics: Acridine Orange; Antibiotics, Antineoplastic; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Separation; Cells, Cultured; Cellular Senescence; Cisplatin; Cysteine Endopeptidases; Dactinomycin; DNA Damage; Electrophoresis, Polyacrylamide Gel; Etoposide; Fibroblasts; Flow Cytometry; Fluorescent Dyes; Humans; Models, Biological; Multienzyme Complexes; Necrosis; Nucleic Acid Synthesis Inhibitors; Proteasome Endopeptidase Complex; Time Factors; Transfection; Tumor Suppressor Protein p53; Ultraviolet Rays | 2001 |
The mechanism of killing and exiting the protozoan host Acanthamoeba polyphaga by Legionella pneumophila.
Topics: Acanthamoeba; Animals; Annexin A5; Apoptosis; Coloring Agents; Dactinomycin; Fluorescein-5-isothiocyanate; In Situ Nick-End Labeling; Legionella pneumophila; Microscopy, Confocal; Mutation; Necrosis; Propidium | 2000 |
Rapid extracellular release of cytochrome c is specific for apoptosis and marks cell death in vivo.
Topics: Adult; Aged; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Biomarkers; Biomarkers, Tumor; Chick Embryo; Cysteine Proteinase Inhibitors; Cytochrome c Group; Cytosol; Dactinomycin; Enzyme Inhibitors; Extracellular Space; Female; Hematologic Neoplasms; Humans; Hydrogen Peroxide; Jurkat Cells; L Cells; L-Lactate Dehydrogenase; Male; Mice; Middle Aged; Mitochondria; Necrosis; Neoplasm Proteins; Nucleic Acid Synthesis Inhibitors; Protein Transport; Staurosporine; Tumor Necrosis Factor-alpha | 2001 |
Pharmaceutical-induced cell apoptosis characterized by capillary zone electrophoresis.
Topics: Animals; Apoptosis; Cell Line; Dactinomycin; DNA Damage; DNA Fragmentation; Electrophoresis, Agar Gel; Electrophoresis, Capillary; Insecta; Necrosis | 2001 |
Stimulation of RNA synthesis in L-929 cells by rabbit tumor necrosis factor.
Topics: Animals; BCG Vaccine; Cell Survival; Cells, Cultured; Corynebacterium; Cytotoxins; Dactinomycin; Endotoxins; Mice; Mycobacterium bovis; Necrosis; Neoplasms; Rabbits; RNA; Uridine | 1979 |
The acute effects of various cytotoxic compounds injected into the prostate glands of dogs.
Topics: Animals; Antineoplastic Agents; Dactinomycin; Dogs; Ethoglucid; Fluorouracil; Inflammation; Injections; Male; Mitomycins; Necrosis; Prostate; Thiotepa | 1978 |
Cerebral necrosis following irradiation and chemotherapy for metastatic choriocarcinoma.
Topics: Adult; Antineoplastic Agents; Brain; Brain Diseases; Brain Neoplasms; Chlorambucil; Choriocarcinoma; Dactinomycin; Female; Humans; Methotrexate; Necrosis; Neoplasm Metastasis; Pregnancy; Radiation Injuries; Radiotherapy; Tomography, X-Ray Computed; Uterine Neoplasms | 1977 |
An electron-microscope study of the mode of cell death induced by cancer-chemotherapeutic agents in populations of proliferating normal and neoplastic cells.
Topics: Animals; Antineoplastic Agents; Ascitic Fluid; Cell Count; Cell Nucleus; Cell Survival; Cilia; Cycloheximide; Cytarabine; Dactinomycin; Endoplasmic Reticulum; Epithelial Cells; Epithelium; Golgi Apparatus; Injections, Intraperitoneal; Intestinal Mucosa; Lysosomes; Male; Microscopy, Electron; Mitochondria; Mitomycins; Necrosis; Neutrophils; Rats; Ribosomes; Sarcoma 180; Time Factors | 1975 |
Severe chemotherapy-related hepatic toxicity associated with MZ protease inhibitor phenotype.
Topics: Alleles; alpha 1-Antitrypsin; alpha 1-Antitrypsin Deficiency; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Dactinomycin; Disease Susceptibility; Hemorrhage; Heterozygote; Humans; Infant; Kidney Neoplasms; Liver Diseases; Liver Transplantation; Male; Necrosis; Phenotype; Vincristine; Wilms Tumor | 1990 |
Disparate histologic responses in simultaneously resected primary and metastatic osteosarcoma following intravenous neoadjuvant chemotherapy.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Necrosis; Osteosarcoma; Postoperative Care; Preoperative Care; Vincristine | 1987 |
Preservation of anaplastic features in Wilms' tumors after preoperative chemotherapy.
Topics: Anaplasia; Child; Dactinomycin; Humans; Necrosis; Preoperative Care; Vincristine; Wilms Tumor | 1989 |
Treatment methods for extravasations of chemotherapeutic agents: a comparative study.
Topics: Animals; Antidotes; Antineoplastic Agents; Carmustine; Dactinomycin; Debridement; Disease Models, Animal; Doxorubicin; Extravasation of Diagnostic and Therapeutic Materials; Injections, Intradermal; Irritants; Mitomycins; Necrosis; Rats; Skin Ulcer; Time Factors; Vincristine | 1986 |
[Studies on understanding the problematics of radiologic-cytostatic combination treatment. 8. Syncytostatic studies using actinomycin].
Topics: Animals; Antineoplastic Agents; Body Weight; Dactinomycin; Edema; Growth; Growth Disorders; Male; Mice; Necrosis; Organ Size; Radiation Effects; Radiotherapy Dosage; Tail; Testis; Wound Healing | 1970 |
Epiphyseal osteonecrosis in transplanted patients: effect of surgical treatment.
Topics: Adolescent; Adult; Age Factors; Antilymphocyte Serum; Arthroplasty; Azathioprine; Bone Diseases; Child; Dactinomycin; Epiphyses; Female; Femur Head Necrosis; Glucocorticoids; Hip; Humans; Kidney Transplantation; Male; Middle Aged; Necrosis; Prednisolone; Prostheses and Implants; Radiography; Transplantation, Homologous | 1972 |
[Brain injuries induced in the cat by actinomycind injected into the cerebrospinal fluid; comparison with actimomycinic acid].
Topics: Animals; Brain; Brain Diseases; Cats; Dactinomycin; Electrodes, Implanted; Electroencephalography; Granuloma; Injections, Spinal; Meningitis; Necrosis; Seizures | 1974 |
Triple therapy for leiomyosarcoma of kidney.
Topics: Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Head and Neck Neoplasms; Humans; Kidney Neoplasms; Leiomyosarcoma; Lung Neoplasms; Male; Middle Aged; Necrosis; Neoplasm Metastasis; Nephrectomy; Piperazines; Radiography | 1974 |
The effect of actinomycin D on differentiation of odontoblasts in the rat.
Topics: Ameloblasts; Animals; Cell Differentiation; Dactinomycin; Dental Pulp; Dentin; Edema; Incisor; Necrosis; Odontoblasts; Rats; Tooth Diseases; Tooth Germ | 1972 |
The morphology of various types of cell death in prenatal tissues.
Topics: Abnormalities, Drug-Induced; Animals; Cell Survival; Cyclophosphamide; Dactinomycin; Embryo, Mammalian; Embryonic and Fetal Development; Female; Fetus; Magnesium Deficiency; Mercaptopurine; Mice; Mice, Inbred Strains; Microscopy, Electron; Necrosis; Niacinamide; Pregnancy; Rats; Rats, Inbred Strains; Vincristine; Vitamin A | 1973 |
Modification of acute radiation effect on cerebellar neurons of mice by actinomycin D.
Topics: Animals; Cerebellar Cortex; Dactinomycin; Mice; Necrosis; Purkinje Cells; Radiation Effects; Time Factors | 1968 |
Puromycin-induced necrosis of crypt cells of the small intestine of mouse.
Topics: Animals; Antimetabolites; Autoradiography; Cell Division; Cytarabine; Dactinomycin; DNA; Heart; Intestine, Small; Leucine; Liver; Male; Mice; Necrosis; Nucleosides; Protein Biosynthesis; Proteins; Puromycin; RNA; Spleen; Thymidine; Tritium; Uridine | 1966 |