dactinomycin and Leukemia P388

dactinomycin has been researched along with Leukemia P388 in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199015 (65.22)18.7374
1990's8 (34.78)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chignell, CF; Cox, MG; Cysyk, RL; Sinha, BK1
Kelly, C; Kogan, Y; Sengupta, SK; Szabo, J1
Anderson, JE; Beltz, WR; Kogan, Y; Madhavarao, MS; Sengupta, SK; Trites, DH1
Blondin, J; Kelly, C; Madhavarao, MS; Sengupta, SK1
Corbett, TH; Griswold, DP; Laster, WR; Schabel, FM; Skipper, HE; Trader, MW1
Fujikura, R; Inaba, M; Sakurai, Y1
Behrens, CH; Behrens, DL; Chen, SF; Fredericks, JR; Kirshenbaum, MR; Papp, LM; Polkus, ST; Sipple, P; Stafford, MM; Sun, JH1
Bickle, QD; Lawson, BW; Taylor, MG1
Ling, YH; Perez-Soler, R; Priebe, W1
Inaba, M; Sakurai, Y1
Hanada, M; Hatori, M; Kamei, H; Konishi, M; Nishiyama, Y; Sugawara, K1
Chan, PK; Finch, RA1
Demidova, NS; Goncharova, SA; Konovalova, NP; Shiriaeva, OA1
Inada, H; Kikuchi, J; Kiue, A; Kohno, K; Naito, A; Okumura, M; Sano, T; Sato, S; Suzuki, K; Takano, H1
Brusentsov, NA; Glazkova, TIu; Iavorskaia, NP; Iurchenko, NIa1
Durr, FE; White, RJ1
Aldrich, MB; Chan, PK; Yung, BY1
Chou, CF; Liao, CL; Liu, YT; Shou, L; Yeh, SJ1
Ganapathi, R; Grabowski, D; Israel, M; Schmidt, H; Seshadri, R1
Kelly, C; Sehgal, RK; Sengupta, SK1
Cole, MD; Schuler, GD1
Inaba, M1
DeKoning, TF; Li, LH; Wallace, TL1

Other Studies

23 other study(ies) available for dactinomycin and Leukemia P388

ArticleYear
Synthesis and biological properties of N2-substituted spin-labeled analogues of actinomycin D.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:9

    Topics: Animals; Circular Dichroism; Dactinomycin; DNA; DNA-Directed RNA Polymerases; Electron Spin Resonance Spectroscopy; Hot Temperature; In Vitro Techniques; Leukemia L1210; Leukemia P388; Male; Mice; Nucleic Acid Denaturation; Spin Labels

1979
New actinomycin D analogues as superior chemotherapeutic agents against primary and advanced colon tumors and colon xenografts in nude mice.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:4

    Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Dactinomycin; Humans; Leukemia L1210; Leukemia P388; Male; Mice; Mice, Nude; Neoplasm Transplantation; Transplantation, Heterologous; Tumor Cells, Cultured

1988
N2- and C-7 substituted actinomycin D analogues: synthesis, DNA-binding affinity, and biochemical and biological properties. Structure-activity relationship.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:9

    Topics: Animals; Chemical Phenomena; Chemistry, Physical; Dactinomycin; DNA; Drug Stability; Humans; In Vitro Techniques; Leukemia P388; Male; Mice; Nucleic Acid Denaturation; Rats; RNA; Structure-Activity Relationship

1981
Tetracyclic chromophoric analogues of actinomycin D: synthesis, structure elucidation and interconvertibility from one form to another, antitumor activity, and structure-activity relationships.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:11

    Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Dactinomycin; Drug Evaluation, Preclinical; Humans; Indicators and Reagents; Leukemia P388; Leukemia, Lymphoid; Male; Mice; Spectrophotometry; Structure-Activity Relationship

1983
Concepts for controlling drug-resistant tumor cells.
    European journal of cancer, 1980, Volume: Suppl 1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Body Burden; Cisplatin; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Resistance; Fluorouracil; Leukemia L1210; Leukemia P388; Mammary Neoplasms, Experimental; Mice; Osteosarcoma; Sarcoma, Experimental

1980
Active efflux common to vincristine and daunorubicin in vincristine-resistant P388 leukemia.
    Biochemical pharmacology, 1981, Jul-01, Volume: 30, Issue:13

    Topics: Animals; Cells, Cultured; Dactinomycin; Daunorubicin; Doxorubicin; Drug Resistance; Leukemia P388; Leukemia, Experimental; Mice; Vincristine

1981
(R,R)-2,2'-[1,2-ethanediylbis[imino(1-methyl-2,1-ethanediyl)]]- bis[5-nitro-1H-benz[de]isoquinoline-1,3-(2H)-dione] dimethanesulfonate (DMP 840), a novel bis-naphthalimide with potent nonselective tumoricidal activity in vitro.
    Cancer research, 1994, Apr-15, Volume: 54, Issue:8

    Topics: Amsacrine; Animals; Antineoplastic Agents; Cell Division; Clinical Trials, Phase I as Topic; Colonic Neoplasms; Dactinomycin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Isoquinolines; KB Cells; Kinetics; Leucine; Leukemia L1210; Leukemia P388; Mammary Neoplasms, Experimental; Melanoma; Melanoma, Experimental; Mesylates; Mice; Mitoxantrone; Thymidine; Transplantation, Heterologous; Tumor Cells, Cultured; Uridine

1994
Mechanisms involved in the loss of antibody-mediated adherence of macrophages to lung-stage schistosomula of Schistosoma mansoni in vitro.
    Parasitology, 1993, Volume: 106 ( Pt 5)

    Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Antigens, Surface; Cell Adhesion; Cells, Cultured; Dactinomycin; Female; Immune Sera; Kinetics; Larva; Leukemia P388; Lung; Macrophages; Male; Mice; Opsonin Proteins; Puromycin; Rabbits; Rats; Schistosoma mansoni; Tumor Cells, Cultured

1993
Apoptosis induced by anthracycline antibiotics in P388 parent and multidrug-resistant cells.
    Cancer research, 1993, Apr-15, Volume: 53, Issue:8

    Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Calcium; Cell Membrane; Cycloheximide; Dactinomycin; DNA Damage; Doxorubicin; Drug Resistance; Leukemia P388; Mice; Tumor Cells, Cultured

1993
Enhanced efflux of actinomycin D, vincristine, and vinblastine in adriamycin-resistant subline of P388 leukemia.
    Cancer letters, 1979, Volume: 8, Issue:2

    Topics: Animals; Cell Line; Dactinomycin; Doxorubicin; Drug Resistance; Leukemia P388; Leukemia, Experimental; Mice; Vinblastine; Vincristine

1979
Protactin, a new antibiotic metabolite and a possible precursor of the actinomycins.
    The Journal of antibiotics, 1992, Volume: 45, Issue:1

    Topics: Amino Acid Sequence; Amino Acids; Animals; Antibiotics, Antineoplastic; Bacteria; Carcinoma; Chromatography, Thin Layer; Colorectal Neoplasms; Dactinomycin; Female; Fermentation; Fungi; Humans; Hydrolysis; Leukemia L1210; Leukemia P388; Magnetic Resonance Spectroscopy; Mass Spectrometry; Melanoma, Experimental; Mice; Molecular Sequence Data; Molecular Structure; Oligopeptides; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Streptomyces; Tumor Cells, Cultured

1992
Studies of actinomycin D induced B23-translocation in P388D1 cells implanted in DBA/2 mice.
    Oncology, 1992, Volume: 49, Issue:3

    Topics: Animals; Dactinomycin; Dose-Response Relationship, Drug; Female; Fluorescent Antibody Technique; Leukemia P388; Mice; Mice, Inbred DBA; Neoplasm Transplantation; Nuclear Proteins; Nucleophosmin; Time Factors; Translocation, Genetic; Tumor Cells, Cultured

1992
[Features of developing resistance during combined use of antineoplastic agents, causing multiple drug resistance].
    Doklady Akademii nauk SSSR, 1991, Volume: 319, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Colchicine; Dactinomycin; Daunorubicin; Doxorubicin; Drug Resistance; Leukemia P388; Mice; Phenotype; Vincristine

1991
Reversal by two dihydropyridine compounds of resistance to multiple anticancer agents in mouse P388 leukemia in vivo and in vitro.
    Japanese journal of cancer research : Gann, 1990, Volume: 81, Issue:10

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Dactinomycin; Dihydropyridines; Dioxins; Drug Resistance; Drug Synergism; Leukemia P388; Male; Membrane Glycoproteins; Mice; Mice, Inbred Strains; Tritium; Vinblastine; Vincristine; Vindesine

1990
[Antineoplastic activity of combinations of cytostatics and dextran-ferrite administered to mice with leukemia P-388].
    Eksperimental'naia onkologiia, 1990, Volume: 12, Issue:6

    Topics: Animals; Antineoplastic Agents; Cisplatin; Cyclophosphamide; Dactinomycin; Daunorubicin; Doxorubicin; Drug Combinations; Fluorouracil; Iron-Dextran Complex; Leukemia P388; Melphalan; Methotrexate; Mice; Tegafur

1990
Development of mitoxantrone.
    Investigational new drugs, 1985, Volume: 3, Issue:2

    Topics: Animals; Anthraquinones; Antineoplastic Agents; Cell Line; Chemistry, Pharmaceutical; Colonic Neoplasms; Cricetinae; Cricetulus; Dactinomycin; DNA; Doxorubicin; Drug Evaluation; Drug Synergism; Female; Heart; Humans; Intercalating Agents; Interphase; Leukemia L1210; Leukemia P388; Melanoma; Mice; Mitoxantrone; RNA; RNA, Double-Stranded; Structure-Activity Relationship

1985
Nucleolar protein B23 translocation after doxorubicin treatment in murine tumor cells.
    Cancer research, 1987, Jul-15, Volume: 47, Issue:14

    Topics: Animals; Dactinomycin; Daunorubicin; Doxorubicin; Fluorescent Antibody Technique; HeLa Cells; Humans; Leukemia P388; Leukemia, Experimental; Liver Neoplasms, Experimental; Mice; Microscopy, Phase-Contrast; Nuclear Proteins; Nucleophosmin; Ribonucleoproteins; RNA

1987
Mechanism of action of chounghwamycin A.
    Proceedings of the National Science Council, Republic of China. Part B, Life sciences, 1989, Volume: 13, Issue:4

    Topics: Animals; Antibiotics, Antineoplastic; Carcinoma, Ehrlich Tumor; Dactinomycin; DNA; DNA, Circular; Electrophoresis, Agar Gel; Kinetics; Leukemia P388; Protein Biosynthesis; RNA

1989
Calmodulin inhibitor trifluoperazine selectively enhances cytotoxic effects of strong vs weak DNA binding antitumor drugs in doxorubicin-resistant P388 mouse leukemia cells.
    Biochemical and biophysical research communications, 1985, Sep-16, Volume: 131, Issue:2

    Topics: Aminoacridines; Amsacrine; Animals; Anthraquinones; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Line; Dactinomycin; Daunorubicin; DNA; Doxorubicin; Drug Interactions; Drug Resistance; Leukemia P388; Leukemia, Experimental; Menogaril; Mice; Mitoxantrone; Naphthacenes; Nogalamycin; Trifluoperazine

1985
"Reverse" and "symmetrical" analogues of actinomycin D: metabolic activation and in vitro and in vivo tumor growth inhibitory activities.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:5

    Topics: Animals; Biotransformation; Cattle; Chemical Phenomena; Chemistry, Physical; Dactinomycin; DNA; DNA, Neoplasm; Free Radicals; In Vitro Techniques; Leukemia P388; Male; Melanoma; Mice; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; RNA, Neoplasm; Sonication; Superoxides

1985
GM-CSF and oncogene mRNA stabilities are independently regulated in trans in a mouse monocytic tumor.
    Cell, 1988, Dec-23, Volume: 55, Issue:6

    Topics: Animals; Base Sequence; Colony-Stimulating Factors; Dactinomycin; Gene Expression Regulation; Genetic Linkage; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Half-Life; Leukemia P388; Mice; Molecular Sequence Data; Oncogenes; RNA, Messenger; Transcription, Genetic

1988
[Studies on the mechanism of multidrug resistance].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:3 Pt 2

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; Doxorubicin; Drug Resistance; Leukemia P388; Leukemia, Experimental; Mice; Naphthacenes; Podophyllotoxin; Quinacrine; Vinca Alkaloids; Vincristine

1987
Relationship between modulation of natural killer cell activity and antitumor activity of bropirimine when used in combination with various types of chemotherapeutic drugs.
    Cancer research, 1987, Nov-15, Volume: 47, Issue:22

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Cytosine; Cytotoxicity, Immunologic; Dactinomycin; Drug Synergism; Killer Cells, Natural; Leukemia P388; Leukemia, Experimental; Male; Mice; Mice, Inbred Strains

1987