dactinomycin has been researched along with Leukemia, Myeloid in 62 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 39 (62.90) | 18.7374 |
1990's | 20 (32.26) | 18.2507 |
2000's | 3 (4.84) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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AKOPYANTS, SS; BELOVA, ZN; EBERT, MK; GOSHEVA, AE; GRACHEVA, NP; KHARITONOVA, AM; PLANELLES, JJ; SILAEV, AB; SOLOVYEVA, YV | 1 |
FALKSON, G; SNYMAN, HJ | 1 |
RAVINA, A | 1 |
Chang, YS; Choe, YK; Choi, SC; Kim, JT; Kim, JW; Kim, KD; Lim, JS; Paik, SG; Yoon, DY | 1 |
Askin, FB; Bhatia, S; Burden, L; Chen, Z; Dickman, PS; Grier, HE; Krailo, MD; Link, MP; Meyers, PA; Miser, JS; Perlman, EJ; Rausen, AR; Robison, LL; Vietti, TJ | 1 |
Bodner, A; Collins, SJ; Gallo, RC; Ting, R | 1 |
Hozumi, M | 1 |
Honma, Y; Hozumi, M; Kasukabe, T; Nomura, H; Okabe-Kado, J; Tsushima, S | 1 |
Lotem, J; Sachs, L | 3 |
Honma, Y; Hozumi, M; Kasukabe, T; Okabe, J | 1 |
Burgess, AW; Cooper, PC; Metcalf, D | 1 |
Lipton, JH; Sachs, L | 1 |
Andrews, R; Begent, RH; Boshoff, C; Holden, L; Newlands, ES; Oliver, RT; Ong, J; Rustin, GJ; Skelton, M | 1 |
Felix, CA; Hosler, MR; Lange, BJ; Masterson, M; Wilson, AE; Winick, NJ | 1 |
Chen, L; Christman, JK; Xu, M | 1 |
Gileadi, C; Greenberg, PL; Han, JH; Kosek, J; Rajapaksa, R | 1 |
Archimbaud, E; Auzanneau, G; Cony-Makoul, P; Cordonnier, C; Dombret, H; Dreyfus, F; Fenaux, P; Leblond, V; Stoppa, AM; Troussard, X | 1 |
Anzai, N; Hirama, T; Kawabata, H; Masutani, H; Ohmori, M; Okuma, M; Yoshida, Y | 1 |
Drexler, HG; Hu, ZB; Ma, W; Uphoff, CC | 1 |
Behm, FG; Bowman, LC; Head, DR; Heaton, D; Hurwitz, CA; Pui, CH; Raimondi, SC; Sandoval, C | 1 |
Casanova, JL; Cayre, YE; Labbaye, C; Lanotte, M; Miller, WH; Teng, J; Zhang, J | 1 |
Huberman, E; Kharbanda, S; Kufe, D | 1 |
Iversen, PO; Lopez, AF; To, LB | 1 |
Barge, RM; Beyaert, R; Fiers, W; Vandenabeele, P; Willemze, R | 1 |
Kim, DS; Kwon, HJ | 1 |
Graeber, TG; Shuai, K | 1 |
Eddleston, AL; Galbraith, RM; Williams, R; Zuckerman, AJ | 1 |
Hayashi, M; Honma, Y; Hozumi, M; Okabe, J | 1 |
Fekete, B; Hadházy, G; Szabó, B; Szabó, G | 1 |
Honma, Y; Hozumi, M; Okabe, J | 1 |
Da Costa, M; Rothenberg, SP | 1 |
Cieslinski, LB; Torphy, TJ; Zhou, HL | 1 |
Pluznik, DH; Ruhl, S; Schwabe, M | 1 |
Datta, R; Kharbanda, S; Kufe, DW | 1 |
Bauer, KD; Bruno, S; Crissman, HA; Darzynkiewicz, Z | 1 |
Davis, C; Gansbacher, B; Oval, J; Smedsrud, M; Taetle, R | 1 |
Honma, Y; Hozumi, M; Kasukabe, T; Okabe-Kado, J; Umezawa, K | 1 |
Hassan, HT; Rees, J | 1 |
Neville, ME | 1 |
Böhmer, RM; Burgess, AW | 1 |
Chikkappa, G; Pasquale, D; Santella, D; Wang, GJ | 1 |
Champelovier, P; Kolodie, L; Leroux, D; Micouin, C; Seigneurin, D | 1 |
Kawaguchi-Nagata, K; Kitamura, Y; Maeyama, K; Okamura, H; Shoji, K; Tamura, T; Watanabe, T; Yamatodani, A | 1 |
Hamada, H; Naito, M; Tsuruo, T | 1 |
Izawa, M; Shimosato, Y; Terasaki, T | 1 |
Hirji, K; Koeffler, HP; Prokocimer, M; Yelton, L | 1 |
Berrebi, A; Lotem, J; Sachs, L | 1 |
Clarkson, BD; Yataganas, X | 1 |
Artusi, T; Emilia, G; Grossi, G; Mauri, C; Torelli, U | 1 |
Grignani, F; Martelli, MF; Tonato, M | 1 |
Bolognesi, DP; Green, RW; Metzgar, RS; Miller, DS; Mohanakumar, T | 1 |
Garbarino, G; Hulin, N; Masera, P; Pileri, A | 1 |
Bertino, JR; Hillcoat, BL; Swett, V | 1 |
Gergely, L; Hadházy, G; Szegedi, G; Tóth, FD | 1 |
Catovsky, D; Das, KC; Hoffbrand, V; Tripp, E | 1 |
Dierich, MP; Ferrone, S; Pellegrino, MA; Reisfeld, RA | 1 |
De Pasquale, A; Emilia, G; Ferreira, E; Mauri, C; Quaglino, D | 1 |
Akedo, H; Mori, Y; Tanigaki, Y | 1 |
Cline, MJ | 1 |
Bernardelli, R; Brusa, L; Gavosto, F; Pileri, A; Tarocco, RP | 1 |
1 review(s) available for dactinomycin and Leukemia, Myeloid
Article | Year |
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Fundamentals of chemotherapy of myeloid leukemia by induction of leukemia cell differentiation.
Topics: Animals; Arginase; Cell Differentiation; Cell Division; Cell Line; Colony-Stimulating Factors; Dactinomycin; Glucocorticoids; Glycoproteins; Growth Inhibitors; Histones; Humans; Interferons; Interleukin-6; Leukemia Inhibitory Factor; Leukemia, Myeloid; Leukocytes; Lipids; Lymphokines; Lysosomes; Mice; Phenotype; Prostaglandins; Tetradecanoylphorbol Acetate; Vitamin A | 1983 |
1 trial(s) available for dactinomycin and Leukemia, Myeloid
Article | Year |
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Therapy-related myelodysplasia and acute myeloid leukemia after Ewing sarcoma and primitive neuroectodermal tumor of bone: A report from the Children's Oncology Group.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cyclophosphamide; Dactinomycin; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; Incidence; Infant; Leukemia, Myeloid; Male; Neoplasms, Second Primary; Neural Tube Defects; Neuroectodermal Tumors, Primitive; Proportional Hazards Models; Risk; Sarcoma, Ewing; Vincristine | 2007 |
60 other study(ies) available for dactinomycin and Leukemia, Myeloid
Article | Year |
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AURANTIN--A COMPLEX ANTIBIOTIC SUBSTANCE OF THE ACTINOMYCIN GROUP: ITS PROPERTIES AND RESULTS OF CLINICAL TRIALS ON VARIOUS TYPES OF NEOPLASMS.
Topics: Adenocarcinoma; Adrenal Cortex Hormones; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Carcinoma, Ehrlich Tumor; Dactinomycin; Dysgerminoma; Female; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Melanoma; Mice; Neoplasms; Neoplasms, Experimental; Ovarian Neoplasms; Pharmacology; Rabbits; Rectal Neoplasms; Research; Sarcoma; Sarcoma, Experimental; Tissue Culture Techniques | 1964 |
EXPERIENCE WITH CHEMOTHERAPY OF CANCER AT THE UNIVERSITY OF PRETORIA.
Topics: Antineoplastic Agents; Aziridines; Breast Neoplasms; Cyclophosphamide; Dactinomycin; Fluorouracil; Hodgkin Disease; Humans; Intestinal Neoplasms; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma; Lymphoma, Non-Hodgkin; Mannomustine; Mesothelioma; Multiple Myeloma; Neoplasms; Pancreatic Neoplasms; Sarcoma; South Africa; Stomach Neoplasms; Vinblastine | 1964 |
[THE PRACTITIONER AND ANTINEOPLASTIC CHEMOTHERAPY. RECENT DATA].
Topics: Antineoplastic Agents; Dactinomycin; Glioma; Hodgkin Disease; Leukemia; Leukemia, Myeloid; Perfusion; Thiotepa; Urinary Bladder Neoplasms; Wilms Tumor | 1965 |
Expression and regulation of NDRG2 (N-myc downstream regulated gene 2) during the differentiation of dendritic cells.
Topics: Antigens, CD34; CD40 Antigens; Cell Differentiation; Cholecalciferol; Cytokines; Dactinomycin; Dendritic Cells; Dexamethasone; Down-Regulation; Erythroid Precursor Cells; Humans; Leukemia, Myeloid; Lipopolysaccharides; Monocytes; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2003 |
Induction of morphological and functional differentiation of human promyelocytic leukemia cells (HL-60) by componuds which induce differentiation of murine leukemia cells.
Topics: Animals; Antineoplastic Agents; Cell Differentiation; Cell Line; Dactinomycin; Friend murine leukemia virus; Hemin; Humans; Leukemia, Experimental; Leukemia, Myeloid; Mice; Ouabain; Prostaglandins E; Purines; Staining and Labeling; X-Rays | 1980 |
Antileukemic effect of alkyl phospholipids. II. Prolongation of survival times of leukemic mice by alkyl ethyleneglycophospholipids.
Topics: Animals; Cell Differentiation; Dactinomycin; Ethylene Glycols; Leukemia, Myeloid; Mice; Mice, Inbred Strains; Phospholipids | 1983 |
Potential pre-screening for therapeutic agents that induce differentiation in human myeloid leukemia cells.
Topics: Antineoplastic Agents; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Complement C3; Cytarabine; Dactinomycin; Doxorubicin; Humans; Hydroxyurea; Immunoglobulin Fc Fragments; Leukemia, Myeloid; Leukocytes; Mitomycins; Muramidase; Rosette Formation | 1980 |
Survival of mice inoculated with non-differentiating myeloid leukemia cells is prolonged by the injection of an inducer of cell differentiation with a sensitizer.
Topics: Animals; Cell Differentiation; Dactinomycin; Drug Resistance; Drug Therapy, Combination; Female; Leukemia, Experimental; Leukemia, Myeloid; Lipopolysaccharides; Mice | 1980 |
Biochemical and functional characterization of mature progeny purified from a myelomonocytic leukemia cell line.
Topics: Animals; Cell Count; Cell Differentiation; Cell Division; Cell Line; Cell Separation; Clone Cells; Dactinomycin; Esterases; Immune Sera; Leukemia, Myeloid; Mice; Mice, Inbred BALB C; Muramidase | 1982 |
Characterization of macrophage- and granulocyte-inducing proteins for normal and leukemic myeloid cells produced by the Krebs ascites tumor.
Topics: Animals; Biological Assay; Bone Marrow; Carbohydrates; Carcinoma, Krebs 2; Colony-Stimulating Factors; Cycloheximide; Dactinomycin; Drug Stability; Emetine; Granulocytes; Leukemia, Experimental; Leukemia, Myeloid; Macrophages; Mice; Mice, Inbred ICR; Neoplasm Proteins; Peptide Hydrolases; Protease Inhibitors | 1981 |
Secondary tumours following etoposide containing therapy for germ cell cancer.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cohort Studies; Cyclophosphamide; Cytarabine; Dactinomycin; Dose-Response Relationship, Drug; Etoposide; Germinoma; Humans; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Neoplasms, Second Primary; Testicular Neoplasms; Vincristine | 1995 |
ALL-1 gene rearrangements in DNA topoisomerase II inhibitor-related leukemia in children.
Topics: Acute Disease; Adolescent; Bone Marrow Transplantation; Child; Child, Preschool; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 11; Combined Modality Therapy; Dactinomycin; DNA-Binding Proteins; Etoposide; Female; Genes; Histone-Lysine N-Methyltransferase; Humans; Infant; Leukemia; Leukemia, Myeloid; Leukemia, Radiation-Induced; Male; Myelodysplastic Syndromes; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Neoplasms; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogenes; Radiotherapy; Teniposide; Topoisomerase II Inhibitors; Transcription Factors; Translocation, Genetic; Whole-Body Irradiation | 1995 |
Regulation of CD9 expression during 12-O-tetradecanoyl-phorbol-13-acetate- induced differentiation of human myeloid leukemia (HL-60) cells.
Topics: Antigens, CD; Base Sequence; Biomarkers, Tumor; Cell Differentiation; Cycloheximide; Dactinomycin; DNA, Neoplasm; Humans; Leukemia, Myeloid; Membrane Glycoproteins; Methylation; Molecular Sequence Data; RNA, Messenger; Tetradecanoylphorbol Acetate; Tetraspanin 29; Transcription, Genetic; Transcriptional Activation; Tumor Cells, Cultured | 1994 |
Modulation of apoptosis in human myeloid leukemic cells by GM-CSF.
Topics: Apoptosis; Cycloheximide; Dactinomycin; DNA Damage; DNA, Neoplasm; Flow Cytometry; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Tumor Cells, Cultured | 1995 |
[Sequential chemotherapy with or without GM-CSF in acute myeloid leukemia (AML) in the advanced phase: current status of protocols EMA 86 and EMA 91].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Dactinomycin; Drug Administration Schedule; Etoposide; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Methotrexate; Middle Aged | 1994 |
Marked apoptosis of human myelomonocytic leukemia cell line P39: significance of cellular differentiation.
Topics: Apoptosis; Calcimycin; Cell Differentiation; Dactinomycin; Dimethyl Sulfoxide; Humans; Leukemia, Myeloid; Leukemia, Myelomonocytic, Chronic; Tretinoin; Tumor Cells, Cultured | 1994 |
Expression and modulation of annexin VIII in human leukemia-lymphoma cell lines.
Topics: Annexins; Blotting, Northern; Bryostatins; Cell Differentiation; Cholecalciferol; Dactinomycin; Gene Expression Regulation, Neoplastic; Half-Life; Humans; Lactones; Leukemia; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Lymphoma; Macrolides; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1993 |
Secondary acute myeloid leukemia in children previously treated with alkylating agents, intercalating topoisomerase II inhibitors, and irradiation.
Topics: Acute Disease; Adolescent; Alkylating Agents; Antineoplastic Agents; Child; Combined Modality Therapy; Dactinomycin; Doxorubicin; Female; Humans; Intercalating Agents; Leukemia, Myeloid; Male; Neoplasms, Second Primary; Podophyllotoxin; Radiotherapy; Topoisomerase II Inhibitors; Translocation, Genetic | 1993 |
Regulation of myeloblastin messenger RNA expression in myeloid leukemia cells treated with all-trans retinoic acid.
Topics: Cell Cycle; Cell Differentiation; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cycloheximide; Dactinomycin; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Myeloblastin; RNA, Messenger; RNA, Neoplasm; Serine Endopeptidases; Time Factors; Transcription, Genetic; Translocation, Genetic; Tretinoin; Tumor Cells, Cultured | 1993 |
Activation of the jun-D gene during treatment of human myeloid leukemia cells with 1-beta-D-arabinofuranosylcytosine.
Topics: Activating Transcription Factor 2; Base Sequence; Cyclic AMP Response Element Modulator; Cyclic AMP Response Element-Binding Protein; Cytarabine; Dactinomycin; DNA-Binding Proteins; Gene Expression Regulation, Leukemic; Genes, jun; Humans; Kinetics; Leucine Zippers; Leukemia, Myeloid; Molecular Sequence Data; Protein Binding; Protein Processing, Post-Translational; Repressor Proteins; RNA, Messenger; Stimulation, Chemical; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Apoptosis of hemopoietic cells by the human granulocyte-macrophage colony-stimulating factor mutant E21R.
Topics: Acute Disease; Alkaloids; Apoptosis; Cell Division; Cell Survival; Cells, Cultured; Cycloheximide; Cytokines; Dactinomycin; Enzyme Inhibitors; Genistein; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Interleukin-3; Isoflavones; Kinetics; Leukemia, Myeloid; Phosphorylation; Point Mutation; Protein Kinase C; Protein-Tyrosine Kinases; Reference Values; Staurosporine; Stem Cell Factor | 1996 |
Differential involvement of caspases in apoptosis of myeloid leukemic cells induced by chemotherapy versus growth factor withdrawal.
Topics: Animals; Apoptosis; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dactinomycin; Enzyme Activation; Interleukin-3; Leukemia, Myeloid; Mice; Proto-Oncogene Proteins c-bcl-2; Serpins; Tumor Cells, Cultured; Viral Proteins | 1997 |
Identification of an endonuclease secreted by human B lymphoblastic IM9 cells.
Topics: Burkitt Lymphoma; Dactinomycin; Deoxyribonuclease I; DNA, Superhelical; Electrophoresis, Polyacrylamide Gel; Endodeoxyribonucleases; Humans; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid; Magnesium; Plasmids; Protein Synthesis Inhibitors; Substrate Specificity; Tumor Cells, Cultured | 1998 |
Rapid gene repression triggered by interleukin-6 at the onset of monocyte differentiation.
Topics: Antigens, CD; CD24 Antigen; Cell Differentiation; Cycloheximide; Dactinomycin; fms-Like Tyrosine Kinase 3; Gene Expression Regulation; Genes, myb; Genes, myc; Humans; Interleukin-6; Kinetics; Leukemia, Myeloid; Membrane Glycoproteins; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Receptors, Cell Surface; Transcription, Genetic; Tumor Cells, Cultured | 2000 |
Fulminant hepatic failure in leukaemia and choriocarcinoma related to withdrawal of cytotoxic drug therapy.
Topics: Adult; Antineoplastic Agents; Chlorambucil; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Female; Hepatitis B; Hepatitis B Antigens; Humans; Immunosuppression Therapy; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Prednisolone; Pregnancy; Substance Withdrawal Syndrome; Vincristine | 1975 |
Control of normal differentiation of myeloid leukemic cells. VI. Inhibition of cell multiplication and the formation of macrophages.
Topics: Animals; Blood; Bromodeoxyuridine; Cell Adhesion; Cell Differentiation; Cell Division; Cell Movement; Clone Cells; Cycloheximide; Cytarabine; Dactinomycin; Endotoxins; Floxuridine; Hydroxyurea; Idoxuridine; Leukemia, Myeloid; Macrophages; Mice; Mitomycins; Thymidine; Vinblastine | 1975 |
Differentiation of mouse myeloid leukemia cells is inhibited by a factor from non-differentiating leukemia cells.
Topics: Animals; Ascitic Fluid; Cell Line; Clone Cells; Culture Media; Dactinomycin; Drug Resistance; Floxuridine; Growth Inhibitors; Hematopoiesis; Leukemia, Experimental; Leukemia, Myeloid; Leukocytes; Mice; Peptide Hydrolases; Phagocytosis; Rats | 1978 |
Interferon production by human leukaemic leucocytes.
Topics: Adult; Aged; Cells, Cultured; Child; Child, Preschool; Cycloheximide; Dactinomycin; Humans; Immunosuppressive Agents; Interferons; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Middle Aged; Parainfluenza Virus 1, Human; Puromycin | 1976 |
Inhibition of RNA and protein syntheses makes non-differentiating mouse myeloid leukemia cells sensitive to a factor(s) stimulating differentiation.
Topics: Animals; Antibiotics, Antineoplastic; Ascitic Fluid; Cell Differentiation; Cell Line; Cell Movement; Clone Cells; Dactinomycin; Granulocytes; Leukemia, Experimental; Leukemia, Myeloid; Macrophages; Neoplasm Proteins; Phagocytosis; Rats; RNA, Neoplasm | 1977 |
Studies with the folate binding protein in chronic granulocytic leukaemia cells. I. Synthesis and release of binder by cells in short-term culture.
Topics: Carrier Proteins; Chromatography, Agarose; Dactinomycin; Folic Acid; Humans; Leukemia, Myeloid; Protein Binding; Time Factors | 1976 |
Stimulation of beta adrenoceptors in a human monocyte cell line (U937) up-regulates cyclic AMP-specific phosphodiesterase activity.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Albuterol; Cyclic AMP; Cycloheximide; Dactinomycin; Dinoprostone; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid; Monocytes; Protein Kinases; Pyrrolidinones; Receptors, Adrenergic, beta; Rolipram; Tumor Cells, Cultured; Up-Regulation | 1992 |
Interleukin 1 augments the expression of the interleukin 2 receptor alpha-chain in interleukin 6-stimulated myeloid cells by a transcriptional and posttranscriptional mechanism.
Topics: Acute Disease; Animals; Blotting, Northern; Bone Marrow; Dactinomycin; DNA, Neoplasm; Drug Synergism; Flow Cytometry; Half-Life; Interleukin-1; Interleukin-2; Interleukin-6; Iodine Radioisotopes; Leukemia, Myeloid; Mice; Protein Processing, Post-Translational; Receptors, Interleukin-2; RNA, Messenger; Time Factors; Transcription, Genetic; Tumor Cells, Cultured | 1992 |
Transcriptional and posttranscriptional regulation of H1 histone gene expression by 1-beta-D-arabinofuranosylcytosine.
Topics: Cycloheximide; Cytarabine; Dactinomycin; Down-Regulation; Gene Expression Regulation, Leukemic; Histones; Humans; Leukemia, Experimental; Leukemia, Myeloid; Protein Processing, Post-Translational; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1992 |
Changes in cell nuclei during S phase: progressive chromatin condensation and altered expression of the proliferation-associated nuclear proteins Ki-67, cyclin (PCNA), p105, and p34.
Topics: Cell Division; Cell Nucleus; Chromatin; Cyclins; Dactinomycin; DNA Replication; DNA, Neoplasm; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression; Humans; Immunohistochemistry; Ki-67 Antigen; Leukemia, Experimental; Leukemia, Myeloid; Nuclear Proteins; S Phase | 1991 |
Analysis of granulocyte-macrophage colony-stimulating factor action in differentiating myeloid leukemia cells: treatment with DMSO may reveal a common pathway for growth factor gene regulation.
Topics: Blotting, Northern; Cell Differentiation; Cell Line; Dactinomycin; Dimethyl Sulfoxide; Epidermal Growth Factor; ErbB Receptors; Gene Expression Regulation, Leukemic; Genes, myc; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Phenotype; Proto-Oncogene Proteins c-myc; Transcription, Genetic | 1991 |
Inhibition of abl oncogene tyrosine kinase induces erythroid differentiation of human myelogenous leukemia K562 cells.
Topics: Alkaloids; Antibiotics, Antineoplastic; Azepines; Benzoquinones; Cell Differentiation; Cell Division; Dactinomycin; Dose-Response Relationship, Drug; Doxorubicin; Erythrocytes; Genes, abl; Genistein; Humans; Hydroquinones; In Vitro Techniques; Isoflavones; Lactams, Macrocyclic; Leukemia, Myeloid; Myosin-Light-Chain Kinase; Oligonucleotides, Antisense; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-abl; Quinones; Rifabutin; RNA, Messenger; Sphingosine; Staurosporine | 1990 |
Triple combination of retinoic acid plus actinomycin D plus dimethylformamide induces differentiation of human acute myeloid leukaemic blasts in primary culture.
Topics: Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; Dimethylformamide; Drug Interactions; Drug Screening Assays, Antitumor; Humans; Leukemia, Myeloid; Tretinoin; Tumor Cells, Cultured | 1990 |
51Cr-uptake assay. A sensitive and reliable method to quantitate cell viability and cell death.
Topics: Azides; Cell Line; Cell Survival; Chromium Radioisotopes; Cytotoxicity Tests, Immunologic; Dactinomycin; Humans; Leukemia, Experimental; Leukemia, Myeloid; Methods; Mitomycin; Mitomycins; Sodium Azide | 1987 |
Granulocytic colony-stimulating factor (G-CSF) does not induce differentiation of WEHI3B(D+) cells but is required for the survival of the mature progeny.
Topics: Animals; Cell Count; Cell Cycle; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Colony-Stimulating Factors; Dactinomycin; Granulocyte Colony-Stimulating Factor; Granulocytes; Leukemia, Myeloid; Mice; Tumor Cells, Cultured | 1988 |
Granulocyte colony-stimulating factor (G-CSF) induces synthesis of alkaline phosphatase in neutrophilic granulocytes of chronic myelogenous leukemia patients.
Topics: Alkaline Phosphatase; Cells, Cultured; Colony-Forming Units Assay; Colony-Stimulating Factors; Culture Media; Dactinomycin; Enzyme Induction; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Monocytes; Neutrophils; Tumor Cells, Cultured | 1988 |
Establishment and characterization of a granulocytic subclone (UM 384) from the monoblastic cell line U 937.
Topics: Antigens, Differentiation; Butyrates; Butyric Acid; Cell Differentiation; Clone Cells; Dactinomycin; Granulocytes; Histocytochemistry; Humans; In Vitro Techniques; Leukemia, Myeloid; Microscopy, Electron; Monocytes; Tretinoin; Tumor Cells, Cultured | 1989 |
Increase of histidine decarboxylase activity in murine myelomonocytic leukemia cells (WEHI-3B) in parallel to their differentiation into macrophages.
Topics: Animals; Antigens, Surface; Blood; Carboxy-Lyases; Cell Differentiation; Cell Line; Culture Media; Dactinomycin; Escherichia coli; Histamine; Histidine Decarboxylase; Kinetics; Leukemia, Myeloid; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Rats; Rats, Inbred Strains; Tumor Cells, Cultured | 1988 |
ATP/Mg2+-dependent binding of vincristine to the plasma membrane of multidrug-resistant K562 cells.
Topics: Adenosine Triphosphate; Binding Sites; Biological Transport; Camptothecin; Cell Membrane; Dactinomycin; Doxorubicin; Drug Resistance; Fluorouracil; Kinetics; Leukemia, Myeloid; Magnesium; Tumor Cells, Cultured; Verapamil; Vinblastine; Vincristine | 1988 |
Ribosomal RNA on the surfaces of nonleukemic mouse ascites tumor cells.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Line; Cell Membrane; Cell Movement; Centrifugation, Density Gradient; Dactinomycin; Electrophoresis; Fluorescent Antibody Technique; Injections; Leukemia L1210; Leukemia, Experimental; Leukemia, Myeloid; Mice; Pronase; RNA, Ribosomal | 1986 |
Study of differentiation of fresh myelogenous leukemic cells by compounds that induce a human promyelocytic leukemic line (HL-60) to differentiate.
Topics: Adult; Aged; Cell Differentiation; Cell Line; Dactinomycin; Dimethyl Sulfoxide; Humans; Hypoxanthine; Hypoxanthines; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Middle Aged; Nitroblue Tetrazolium; Phagocytosis; Thioguanine | 1985 |
Screening for induction of differentiation and toxicity to blast cells by chemotherapeutic compounds in human myeloid leukemia.
Topics: Antineoplastic Agents; Bone Marrow; Cell Differentiation; Cells, Cultured; Dactinomycin; Drug Evaluation, Preclinical; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Time Factors | 1985 |
Flow microfluorometric analysis of cell killing with cytotoxic drugs.
Topics: Autoanalysis; Bleomycin; Cell Division; Cell Line; Cell Survival; Cytarabine; Dactinomycin; Demecolcine; DNA, Neoplasm; Histocytochemistry; Humans; Hydroxyurea; Leukemia, Myeloid; Methods; Microscopy, Fluorescence; Mitosis; Staining and Labeling; Thymidine; Time Factors; Tritium | 1974 |
[Radioautographic studies on the RNA and protein metabolism of immature cells in acute leukemia. Preliminary report].
Topics: Autoradiography; Dactinomycin; Humans; In Vitro Techniques; Leukemia, Myeloid; Nucleosides; Proteins; RNA, Neoplasm | 1965 |
Dihydrofolic reductase in human blood cells. II. Enzyme activity after amethopterin and actinomycin C administration.
Topics: Blood Cells; Bone Marrow; Bone Marrow Cells; Dactinomycin; Depression, Chemical; Enzyme Induction; Erythrocytes; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocytes; Methotrexate; Stimulation, Chemical; Tetrahydrofolate Dehydrogenase; Time Factors | 1967 |
Human leukemia antigens: partial isolation and characterization.
Topics: Animals; Antigens, Neoplasm; Cell Line; Cell Membrane; Centrifugation; Chromatography, Gel; Cycloheximide; Cytarabine; Cytotoxicity Tests, Immunologic; Dactinomycin; Haplorhini; Histocompatibility Antigens; Humans; Immune Sera; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Lymphocytes; Microscopy, Electron; Neuraminidase; Papain; Potassium Chloride; Pronase; Puromycin; Rabbits; Subcellular Fractions; Temperature; Trypsin | 1974 |
Myeloid cell actinomycin binding in human myeloid leukaemia.
Topics: Autoradiography; Binding Sites; Bone Marrow; Bone Marrow Cells; Chromatin; Dactinomycin; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Tritium | 1974 |
Increase of dihydrofolate reductase activity in cultured mammalian cells after exposure to methotrexate.
Topics: Culture Techniques; Cycloheximide; Dactinomycin; Floxuridine; Humans; Leucine; Leukemia, Myeloid; Lymphocytes; Methotrexate; Neoplasm Proteins; Nucleosides; Puromycin; RNA, Neoplasm; Tetrahydrofolate Dehydrogenase; Tritium | 1967 |
Comparative study on the interferon production by the leukocytes of healthy and leukaemic subjects.
Topics: Amnion; Culture Techniques; Dactinomycin; Humans; Interferons; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Newcastle disease virus; Parainfluenza Virus 1, Human; RNA, Neoplasm; Viral Interference | 1967 |
Transport of methotrexate into normal haemopoietic cells and into leukaemic cells and its effects on DNA synthesis.
Topics: Bone Marrow; Bone Marrow Cells; Carbon Radioisotopes; Culture Techniques; Cyclic AMP; Dactinomycin; Deoxyuridine; DNA; Folic Acid; Humans; Lectins; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphocyte Activation; Methotrexate; Mitosis; Phosphodiesterase Inhibitors; Puromycin; RNA; Theophylline; Thymidine; Tritium | 1973 |
Effect of inhibitors of macromolecular synthesis on HL-A antibody mediated lysis of cultured lymphoblasts.
Topics: Anemia, Sideroblastic; Animals; Burkitt Lymphoma; Carbon Radioisotopes; Cell Line; Cell Membrane; Cells, Cultured; Complement System Proteins; Cycloheximide; Cytotoxicity Tests, Immunologic; Dactinomycin; Depression, Chemical; Histocompatibility Antigens; Humans; Immune Sera; Isoantibodies; Leucine; Leukemia, Myeloid; Lymphocytes; Macromolecular Substances; Puromycin; Rabbits; Thymidine; Time Factors; Tritium | 1974 |
Different blocks in the differentiation of myeloid leukemic cells.
Topics: Animals; Binding Sites, Antibody; Blood; Cell Differentiation; Cell Membrane; Cells, Cultured; Complement System Proteins; Cytarabine; Dactinomycin; Endotoxins; Erythrocytes; Granulocytes; Immune Adherence Reaction; Immunoglobulins; Leukemia, Experimental; Leukemia, Myeloid; Leukocytes; Macrophages; Mice; Prednisolone; Sheep; Uracil | 1974 |
Relationship between RNA metabolism and cell cycle in acute leukaemia.
Topics: Acute Disease; Autoradiography; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Dactinomycin; Humans; Lectins; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphocytes; RNA; Tritium; Uridine | 1972 |
Changes induced by concanavalin A in morphological and adhesive properties of suspension cells.
Topics: Cell Adhesion; Cell Line; Cells, Cultured; Concanavalin A; Cycloheximide; Dactinomycin; Edetic Acid; Galactose; Glass; Glycosides; Humans; Lectins; Leukemia, Myeloid; Lymphoma; Mannose; Mast-Cell Sarcoma; Microscopy, Phase-Contrast; Plant Lectins; Temperature; Trypsin; Vegetables | 1973 |
Ribonucleic acid biosynthesis in human leukocytes: the fate of rapidly labeled RNA in normal and abnormal leukocytes.
Topics: Agammaglobulinemia; Dactinomycin; Humans; Hypertension; Infectious Mononucleosis; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocytes; Lymphatic Diseases; Lymphocytosis; Polycythemia Vera; RNA | 1966 |
Changes in protein metabolism in proliferating and non-proliferating human acute leukaemia cells treated with actinomycin-D.
Topics: Blood Proteins; Dactinomycin; Depression, Chemical; Humans; In Vitro Techniques; Leucine; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphocytes; RNA; Tritium | 1969 |